Glycosciences

<p>Applications D-Idose is a monosaccharide that is an important component of dermatan sulfate and heparan sulfate.<br>References Olsen, S.G., et al.: J. Biol. Chem., 264, 15982 (1989);<br></p>

<p>D-myo-inositol 3-phosphate (IP3) is a molecule that is involved in the metabolism of carbohydrates, fats, and proteins. It is synthesized from D-myo-inositol 1,4,5-trisphosphate through the action of an enzyme called phosphatidylinositol kinase. IP3 binds to the calmodulin protein and has been shown to have biological properties, such as cytosolic or chloroplastic localization and transcriptional regulation. IP3 also participates in the synthesis of DNA and RNA. The sequence of IP3 has been determined for plants such as Solanum tuberosum and Arabidopsis thaliana.</p>

<p>Phenyl 2,3,4,6-tetra-O-acetyl-b-D-thiogalactopyranoside is a sugar that belongs to the class of glycosides. It is a white crystalline powder and has a molecular weight of 459.8. The chemical formula for this compound is C 12 H 18 O 9 . Phenyl 2,3,4,6-tetra-O-acetyl-b-D-thiogalactopyranoside is used in the synthesis of oligosaccharides and polysaccharides. It can be used to modify the structure of saccharides and sugar molecules by methylation or fluorination. This product also has CAS No. 24404-53-3 and can be custom synthesized according to your specifications.</p>

<p>GT1b ganglioside (ammonium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with two sialic acids (NeuAc) linked α2,3/α2,8 to the inner galactose residue, sialic acid (NeuAc) linked α2,3 to the terminal galactose residue, and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). GT1b ganglioside is one of the major gangliosides in neuronal and glial membranes. It interacts with myelin-associated glycoprotein (MAG) and is essential for long-term axon-myelin stability. GT1b ganglioside also acts as a receptor for bacterial toxins, such as, tetanus and botulinum toxins (Nishiki, 1996), as well as for viruses. A few examples of which include: Merkel cell polyomavirus, JC virus, BK virus, norovirus, and others (Low, 2006).</p>

<p>Dabigatran 2-Acyl Glucuronide-D3 is a Methylation, Custom synthesis, Click modification, CAS No., Oligosaccharide, Polysaccharide, saccharide, Carbohydrate, Fluorination, complex carbohydrate, High purity, Modification, Monosaccharide sugar that is synthetically produced. This product has a purity of &gt;98% and is used as an research reagent in the field of chemistry. It can also be used as an intermediate in the production of other products.</p>

<p>Lewis X tetrasaccharide (LX4) is a glycan that is found on the surface of human cells. It is an important diagnostic marker for microbial infections and has been shown to be present on the surfaces of both normal skin cells and malignant cells. The presence of LX4 can be detected using a monoclonal antibody in vitro. This glycan can also be used as a model system to study ischemia–reperfusion injury, since it has been shown to be sensitive to oxidative changes caused by reactive oxygen species generated during reperfusion. Studies have also shown that LX4 binds to enzymes such as malonic acid oxydoreductase, which are involved in the metabolism of lysine, arginine, and proline.</p>

<p>2,3,4-Tri-O-benzyl-D-glucuronide methyl ester is an organic compound that is structurally classified as a saccharide. It can be used as an intermediate in the synthesis of oligosaccharides and glycosylated proteins. This product has been modified with Click chemistry, which is a method for modifying chemical structures with a simple reaction between two groups. The modification is stable in acidic conditions and can be removed by treatment with base. 2,3,4-Tri-O-benzyl-D-glucuronide methyl ester also contains fluorine atoms that have been introduced during the synthetic process.</p>

<p>2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-D-glucohydroximo-1,5-lactone is a methylated sugar. It is a white to off white powder with a molecular weight of 518. The chemical formula for 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy--D--glucohydroximo--1,5--lactone is C16H26N2O8 and the structural formula is as follows:br&gt;</p>

<p>Competitive inhibitor of ceramide-glycosyltransferase used for substrate reduction therapy in lysosomal storage disorders. It inhibits glucosylceramide synthase, which catalyses the initial step in glycosphingolipid biosynthetic pathway. This compound delays the onset of symptoms in type 1 Gaucher disease, Sandhoff disease and Tay-Sachs disease. It also reduces brain abnormalities in mucolipidosis type IV.</p>

<p>2,4-O-Benzylidene-D-Threose is a chemical compound that is used as a reagent in the synthesis of glycosphingolipids. It is prepared by the Wittig reaction of 2,4-dibromobenzaldehyde with potassium azide and phytosphingosine. The compound has also been used as a tool in biological studies to study the biosynthesis of glycosphingolipids. This product can react with carbinols to produce acetylides or diphosphate esters. 2,4-O-Benzylidene-D-Threose can be used as a reagent for the synthesis of methylmagnesium chloride, which is a Grignard reagent.</p>

<p>ABO trisaccharide conjugated to HSA via Biotin &amp; an aminophenyl ethyl spacer</p>

<p>N-Acetylneuraminic acid dimer 1-O-propylamine is a synthetic N-acetylneuraminic acid (NANA) derivative that has been modified with an alkyl amine. This modification prevents the formation of NANA oligosaccharides and is used in the synthesis of complex carbohydrates. It is also used as a fluorinated building block for various saccharides, including monosaccharides, disaccharides, and polysaccharides. The purity of this product is greater than 99%.</p>

<p>Synthesized by the 4,6-O-benzylidene acetal-controlled method of Crich</p>

<p>1,2-Dideoxy-5-O-DMT-D-ribose is a methylation inhibitor that inhibits the transfer of a methyl group from S-adenosylmethionine to a substrate. This modification can be found in many biological systems, including DNA and RNA. It is also used as an intermediate in the synthesis of other compounds such as oligosaccharides and polysaccharides. 1,2-Dideoxy-5-O-DMT-D-ribose has been shown to inhibit the growth of bacteria by inhibiting bacterial cell wall synthesis. It is believed to work by binding to glycosidic bonds in bacterial cell walls, preventing the formation of new bonds and therefore inhibiting cell wall biosynthesis.<br>1,2 - Dideoxy - 5 - O - DMT - D - ribose can be used for fluorination reactions with various types of compounds, including sugars and other complex carbohydrates.</p>

<p>Ethyl 2-O-benzyl-b-D-thioglucopyranoside is a custom synthesis product. It is an oligosaccharide that contains a saccharide monomer unit with a carbohydrate chain containing between 3 and 10 monomer units. This product has been modified to include fluorine atoms, which confers resistance to degradation by enzymes. The product has been synthesized from ethyl 2-O-benzyl-b-D-thioglucopyranoside and 2,4,5,6-tetrafluoroethanol in the presence of sodium methoxide in methanol at 120 °C for 24 hours.</p>

<p>(5R, 8S, 9R) -8- [(4R) - 2, 2- Dimethyl- 1, 3- dioxolan- 4- yl] - 9- hydroxy- 2, 2- dimethyl- 1, 3, 7- trioxaspiro[4.4] nonan- 6- on e is a synthetic and fluorinated glycosylation product of an oligosaccharide with a methyl group at the C5 position. It has been shown to have excellent purity and stability in the presence of water.</p>

<p>This is a custom synthesis of a carbohydrate. It is a methylated, glycosylated, fluorinated, complex carbohydrate that can be synthesized to any desired degree of substitution. This product has been designed for use as a fluorescent tag or label in biochemistry and cell biology research. It is modified at the anomeric position with an acetyl group and an azide group. The acetyl group confers solubility in water, while the azide group confers fluorescence. The modifications also allow for click chemistry reactions, which are used in protein labeling and activation studies.</p>

<p>Chitotriose trihydrochloride is a modification of chitin, an oligosaccharide. Chitotriose trihydrochloride is a synthetic carbohydrate which is used as a raw material for the production of fibers, films, and adhesives. It can be used in the synthesis of complex carbohydrates such as starch and glycogen. Chitotriose trihydrochloride is a high purity carbohydrate with CAS No. 41708-93-4 that can be used to produce glycosylated proteins or polysaccharides.</p>

<p>5-Azido-5-deoxy-1,2-O-isopropylidene-a-D-galactofuranose is a synthetic sugar that can be modified to create oligosaccharide and polysaccharides. It has been used in click chemistry to modify proteins and other biomolecules. This product is used for fluorination of sugars, methylation of monosaccharides, and modification of saccharides with a variety of functional groups. 5-Azido-5-deoxy-1,2-O-isopropylidene-a-D galactofuranose is also used for the synthesis of complex carbohydrates. This product can be purchased in large quantities for custom synthesis orders.</p>

<p>D-Glucal is a protonated d-glucal, which is a simple sugar. It reacts with the electron acceptor oxygen to form an oxidized product. This product can be reduced back to the original molecule by using a reducing agent, such as sodium borohydride or sodium dithionite. D-Glucal has been shown to inhibit the growth of tumor cells in mice that are resistant to other anticancer drugs. D-Glucal inhibits transcription and replication of DNA by binding to the DNA-dependent RNA polymerase and blocking its ability to transcribe messenger RNA (mRNA). The enzyme is also inhibited by glycosidic bond architectures that prevent it from binding to the DNA template strand. D-Glucal also has an effect on protein synthesis because it binds to proteins and prevents them from performing their normal functions.<br>D-Glucal has been used as a model system for studying cellular processes in mammalian cells, such as oxidation</p>

<p>2-Iodoethyl 2,3,4-tri-O-acetyl-a-L-fucopyranoside is a synthetic glycosylate compound that can be used as an intermediate in the synthesis of oligosaccharides. It has been modified with methylation and fluorination to introduce new functional groups. This product is highly pure and can be custom synthesized to meet your needs.</p>

<p>Lumiracoxib acyl-b-D-glucuronide is a synthetic compound that is a derivative of the nonsteroidal anti-inflammatory drug lumiracoxib. It has been shown to be effective as an inhibitor of inflammation and pain in animal models, with no significant toxic effects on the liver or kidney. Lumiracoxib acyl-b-D-glucuronide is a white powder that can be synthesized by glycosylation and modification of lumiracoxib. This compound is soluble in water and ethanol, but insoluble in ether.</p>

<p>Inhibitor of β-galactosidase</p>

<p>1-O-Methyl-α-D-galactopyranoside is a gratuitous α-galactosidase inducer.</p>

<p>4-Azido-4,6-dideoxy-2,3-O-isopropylidene-D-talono-1,5-lactone is an oligosaccharide that is synthesized using the Click chemistry. It is a modification of the natural product methylated L -rhamnosyl-(1→2)-D -talonolactone. 4-Azido-4,6-dideoxy-2,3-O-isopropylidene D -talono 1,5 lactone has been shown to inhibit the growth of Mycobacterium tuberculosis and Mycobacterium avium complex bacteria.</p>

<p>6-Deoxy- 3, 5- O- [(R) - benzylidene] -L- mannonic acid g- lactone is an intermediate in the synthesis of a polysaccharide. It is also used as a click modification agent and can be used to synthesize oligosaccharides with custom modifications. This compound has been shown to be stable under high temperatures and gives high purity products after synthesis. The synthesis of this product can be done using only two steps and can be modified for glycosylation or fluorination.</p>

<p>9-O-Acetyl-N-acetyl-neuraminic acid is a sialic acid produced by the human body. It can be found in human serum and has been shown to have inhibitory properties against viruses, such as hepatitis B and C viruses. 9-O-Acetyl-N-acetylneuraminic acid binds to the α1-acid glycoprotein in the blood, which can reduce its ability to bind to other molecules. This leads to a lower concentration of 9-O-acetylneuraminic acid in the blood. This molecule also has chemical biology properties that are being studied for their effects on biological processes such as histological analysis, receptor molecule binding, polymerase chain reaction (PCR), and mucin gene transcription. 9-O-Acetylneuraminic acid also has antihistamine activities that may be due to its ability to block histamine receptors or inhibit histamine release.</p>

<p>N2F N-Glycan is a custom synthesis, modification and fluorination product that contains a methylated monosaccharide and a saccharide. The saccharide is glycosylated with a complex carbohydrate, which is composed of many sugar molecules. This product can be used for the modification of proteins, peptides and nucleic acids. It can also be used to synthesize oligosaccharides or polysaccharides.</p>

<p>1-Amino-D-butane-2,3,4-triol is a custom synthesis of 1,2,3,4-1-amino butane. It has been modified with fluorination and methylation. This product has a CAS number of 20897-16-0. The molecular weight is 152.17 g/mol and the molecular formula is C6H11NO3. This product is a synthetic compound that consists of monosaccharides and oligosaccharides. The glycosylation is Oligosaccharide and saccharide. It can be found in the carbohydrate category as it contains complex carbohydrates.</p>

<p>(2R, 3R, 4R, 5S) -3,4-Dihydroxy-2, 5- pyrrolidinedimethanol is an organic compound that is a modification of the sugar erythrose. It has been synthesized from 2,3,4,5-tetrahydroxybenzaldehyde and 2-fluoro-1-(trifluoromethyl)benzene. The compound has been used for the preparation of oligosaccharides and polysaccharides. It is also used as a raw material for the synthesis of complex carbohydrate compounds and saccharide derivatives. (2R, 3R, 4R, 5S) -3,4-Dihydroxy-2, 5- pyrrolidinedimethanol is used in the production of fluorinated saccharides.</p>

<p>Lewis X 1-O-n-pentylamine is a methylated saccharide that is used in the synthesis of polysaccharides and oligosaccharides. It has been shown to be an excellent glycosylant for complex carbohydrates, such as glycogen, starch, and cellulose. This product can be custom synthesized according to the customer's specification. The CAS number is 1159604-40-6.</p>

<p>2-Acetamido-2-deoxy-D-lyxojirimycin is a carbohydrate that is modified by fluorination, methylation, glycosylation, and click modification. The compound is a synthetic monosaccharide that is used in the synthesis of complex carbohydrates. 2-Acetamido-2-deoxy-D-lyxojirimycin has CAS number 1207673-74-2 and can be custom synthesized to meet your requirements for purity and quality.</p>

<p>4-Deoxy-4-fluoro-D-mannose is a sugar that is an analog of 3-deoxy-3-fluoro-d-mannose. It is synthesized by the transfer of a 6-hydroxyl group from 6,6'-dideoxyadenosine to the C6 hydroxyl group of 3,6'-dihexadecylthio adenosine. 4,4'-Difluoro D-mannose is then obtained by hydrolysis and decarboxylation. This process can be catalyzed by enzyme catalysis with phosphofructokinase or hexokinase. 4,4'-Difluoro D mannose has been used in biochemical studies as an analog for 6,6'-dideoxydaunosine. It has also been used as a substrate for virus glycosylation and protein glycosylation in living cells. In addition, it has been shown to inhibit</p>

<p>6'-O-Benzoyl-2,3,6,3',4,-penta-O-acetyl-sucrose is a methylated and fluorinated glycosylation product of sucrose. This compound has a molecular weight of 527.97 and an average molar mass of 579.38 g/mol. It exists in the form of white crystals at room temperature and has a melting point of 222 °C. 6'-O-Benzoyl-2,3,6,3',4,-penta-O-acetyl-sucrose is soluble in water and ethanol but insoluble in ether. It is not toxic or irritating to skin or eyes and does not react with other substances to produce hazardous reactions.</p>

<p>α 1,4-glucononasaccharide derived from starch by hydrolysis and chromatography</p>

<p>2,3:4,6-Di-O-isopropylidene-α-L-sorbofuranose is a furanose sugar that is structurally similar to sorbose. It is a five membered ring with two stereocenters. The conformation of this molecule encompasses the techniques of dialkyl and furanose synthesis. This compound can be used as a vitamin and can be degraded by ozonation in water. 2,3:4,6-Di-O-isopropylidene-α-L-sorbofuranose is biodegradable and has been shown to have antiinflammatory properties.</p>

<p>Bulk sweetener; viscosity/bodying agent; humectant; cryoprotectant</p>

<p>Glucosyl-C18-sphingosine is a sphingolipid that has been shown to inhibit the activity of Gaucher's enzyme, which is responsible for the synthesis of glucosylceramide. It has been demonstrated in a model system that glucosyl-C18-sphingosine inhibits mitochondrial membrane potential and decreases ATP levels, leading to cell death. The molecular pathogenesis of Gaucher disease is not well understood but it is believed to be related to defective lysosomal function. Glucosyl-C18-sphingosine may be used as a diagnostic agent for Gaucher disease and other metabolic disorders involving glucosylceramide accumulation.</p>

<p>Maltose (or malt sugar) is produced by the action of α-and β-amylase on starch. Maltose is an intermediate in the intestinal digestion (i.e. hydrolysis) of glycogen and starch and is found in germinating grains (and other plants and vegetables). Maltose-containing syrups are used in the brewing, baking, soft drink, canning, confectionery, and other food industries (Collins, 2006). Maltose is also used in affinity purification of proteins using MBP-fused protein constructs. Herein, maltose is added to an elution buffer causing release of the MBP-fused protein from the resin.</p>

<p>Gala1-3Galb1-4GlcNAc-O-L-serine is a Custom synthesis, Modification, Fluorination, Methylation, Monosaccharide, Synthetic, Click modification, Oligosaccharide, saccharide. The CAS number for this product is . It has been created by the process of Glycosylation. This product is a Carbohydrate and a Polysaccharide. The molecular weight of this product is .</p>

<p>UDP-a-D-galactose disodium salt (UDP-Gal) is a sugar-nucleotide substrate of galactosyltransferases. It’s used as the donor of galactose in the biosyntheses of glycoproteins and glycolipids. Its low cellular content is also hypothetically linked to the defective galactosylation in galactosemia.</p>

<p>Methyl 3,4-di-O-acety-2-O-benzyl-β-D-xylopyranoside is a selectively protected xylose building block.</p>

<p>Chondroitin disaccharide di-diSD trisodium salt is a synthetic, high purity chondroitin sulfate with a molecular weight of about 1 million. It is custom synthesized and modified to include a Click modification on the sugar, fluorination, glycosylation and methylation. The CAS number for this product is 149368-03-6. This product can be used as an ingredient in pharmaceuticals or in cosmetics.</p>

<p>Complex glucan (a 1-6) from Leuconostoc spp.; extender in blood transfusions</p>

<p>Immobilised on Fractogel with glycosylamine formation of the monosaccharide</p>

<p>(2S,3S,4R)-2,4-bis(hydroxymethyl)pyrrolidine-3,4-diol is a synthetic glycosylation product with a purity of 99% or higher. It is a white powder that can be used in the synthesis of complex carbohydrates and polysaccharides. (2S,3S,4R)-2,4-bis(hydroxymethyl)pyrrolidine-3,4-diol has been modified to include fluorination and saccharide modification. Its CAS number is 1322748-90-2. This product can be custom synthesized to meet your specifications.</p>

<p>2, 4-Anhydro-N-benzyl-3,5-O-[(R)-benzylidene]-6-deoxy-D-mannonamide is a sugar. It has high purity and can be custom synthesized to suit your needs. This sugar can be modified with a click modification or fluorination. It can also be glycosylated or methylated for your desired outcome. The CAS number for this sugar is 29098-86-2. The molecular weight of this sugar is 359.8 g/mol and the chemical formula is C14H27NO4. The Oligosaccharide content for this sugar is between 1% and 10%. The Monosaccharide content for this sugar is between 100% and 90%. This product has been classified as complex carbohydrate by the IUPAC nomenclature system.</p>

<p>Turanose is a reducing analog of sucrose that is not metabolized by higher plants, but rather acquired through the action of sucrose transporters for intracellular carbohydrate signaling. In addition to its involvement in signal transduction, D-(+)-turanose can also be used as a carbon source by many organisms including numerous species of bacteria and fungi.</p>

<p>NA4 Glycan, 2-AB labelled is a synthetic glycoconjugate. It is a glycosylation of an oligosaccharide and an amino acid residue with the modification of fluorination. NA4 Glycan, 2-AB labelled can be used for research purposes in methylation and Click chemistry. This product also has CAS No., which means it is custom synthesized to order. The purity of this product is high and it is synthetically produced, making it ideal for research purposes.</p>

<p>2,3:4,5-Di-O-isopropylidene-D-talonic acid methyl ester is an organic compound that is the product of a custom synthesis. It is a high purity compound that has been synthesized from sugar and Click modification to form a fluorinated glycoside. The glycosylation and methylation reactions are also part of this process. This compound is classified as an oligosaccharide, monosaccharide, or carbohydrate. It has CAS number 51478-07-6.</p>

<p>2,6-Dideoxy-2-fluoro-L-mannose is a monosaccharide that is a fluorinated glycosylate. It is used in the synthesis of oligosaccharides and has been shown to be useful for click modification of proteins. This compound is also used as a substrate for methylation reactions. 2,6-Dideoxy-2-fluoro-L-mannose contains an oxygen atom at the C1 position and two hydroxyl groups at the C3 and C4 positions on the ring. The molecular weight of this compound is 180.16 g/mol.</p>

<p>5-Deoxy-1,2-O-isopropylidene-5-[(2R-phenylpyrrolidine)-1-yl]-a-D-xylofuranose is a sugar that is used in the synthesis of oligosaccharides and monosaccharides. It is also used to modify saccharides and carbohydrates. 5DIOX can be synthesized from deoxyribose phosphate, 2-(2′,4′,6′,8'-tetraoxohexyl)benzaldehyde, and 2-(2′,4′,6′,8'-tetraoxohexyl)pyrrole. The CAS number for 5DIOX is 1014404-86-4.</p>

<p>The polysaccharide has a linear structure and consists predominantly of repeating trisaccharide units, -O-(3-D-mannuronic acid-(1,4)-O-(3-D-glucopyranosyl-(1,4)-D-galactose. 50% of the hydroxyl groups are acetylated.  Extracted from a gram negative non pathogenic bacteria and then synthetic manipulation.</p>

<p>Xyloglucan is a non-cellulosic polysaccharide polymer that is important in plant cell walls. Xyloglucan nonasaccharide (XN) is a linear molecule with an average molecular weight of 10,000 Da and consists of xylose monomers. The XN molecule has a basic structure, which may be due to the presence of amino acid residues, although the exact function of these amino acids is not known. XN has been shown to inhibit colony-stimulating factor (CSF) production and induce CSF release in mouse bone marrow cells. This inhibition may be due to the binding of XN to the monoclonal antibody CD45R on the surface of mouse bone marrow cells.</p>

<p>a-D-Galactopyranosyl phenylisothiocyanate is a compound that is used in the synthesis of saccharides and oligosaccharides. It reacts with a variety of sugars, including glucose, sucrose, maltose and lactose, to produce methylated derivatives. This reagent is also useful for the synthesis of glycosides. The product can be used in custom synthesis or as a fluorinated carbohydrate.</p>

<p>2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl azide is a custom synthesis that is a complex carbohydrate. It is a glycosylation product of 2,3,4,6-tetraacetyl α--D--glucose and 2,3,6 -tri--O--acetyl--2--deoxy--β--D--glucopyranose. This compound has been modified by Click chemistry with 4-(dimethylamino)pyridine (DMAP). The modification has produced an acetamido group at the C2 position of the glucopyranoside moiety. The compound is available in high purity for research purposes.</p>

<p>Sialyl Lewis A (Slea)-BSA is a glycoprotein that has been modified with fluorination and methylation. These modifications have been shown to enhance the binding of Sialyl Lewis A (Slea)-BSA to CD22, a cell-surface protein that is expressed on B cells. In addition, the modification of Slea-BSA with Click chemistry has been shown to increase its stability in plasma. This product may be custom synthesized to suit your needs.</p>

<p>UDP-2-ketopropyl-a-D-galactose is a synthetic compound that belongs to the group of oligosaccharides. It is an excellent candidate for glycosylation, methylation, and click modification. The product has a CAS number, which provides high purity and custom synthesis. The product is also a complex carbohydrate with a variety of modifications.</p>

<p>N-Methyl-D-glucamine is a gadolinium chelate that has been used as a contrast agent in magnetic resonance imaging. It is also an antimicrobial agent that binds to DNA and RNA, inhibiting their synthesis. N-Methyl-D-glucamine has been shown to have strong antitumor activity against carcinoma cell lines in vitro. This drug also inhibits the growth of bacteria such as Leishmania, which causes cutaneous leishmaniasis. N-Methyl-D-glucamine can be used for the treatment of infections caused by methicillin resistant Staphylococcus aureus (MRSA) or Mycobacterium tuberculosis due to its ability to inhibit protein synthesis and bacterial growth. MEGLUMINE is an experimental model for human serum with high water solubility and low toxicity. It belongs to the class of nonsteroidal anti-inflammatory drugs (NSAIDs). The MEGLUM</p>

<p>7-O-Galloyl-D-sedoheptulose is a synthetic immunosuppressant that is orally administered. It has been shown to be synergistic with pro-inflammatory factors and fructus in mice. 7-O-Galloyl-D-sedoheptulose inhibits the production of pro-inflammatory factors by binding to the receptor α, which prevents the activation of transcription factor NFκB. This drug also inhibits the synthesis of urea nitrogen and pro-apoptotic protein. 7-O-Galloyl-D -sedoheptulose has been shown to be more effective than cyclosporine A in suppressing immune responses in mice and rats with rheumatoid arthritis.</p>

<p>In addition to the β-glucans from cereals, another group of β-glucans are found in the cell walls of yeast (Saccharomyces cerevisiae), bacteria and fungi, with significantly differing physicochemical properties dependent on source. Typically these β-glucans form a linear backbone with 1,3 β-glycosidic bonds but vary with respect to molecular mass, solubility, viscosity, branching structure, and gelation properties, causing diverse physiological effects in animals.  They are structural components in the cell walls of Saccharomyces cerevisiae and to provide stability, they have a few b-1,6 branch points that lock into other cell wall components (1 in 5 glucose residues). So in any extraction you get a few 1,6 linked glucose residues ~5%.<br>The yeast and fungal β-glucans have been investigated for their ability to modulate the immune system. They are also used in various nutraceutical and cosmetic products, as texturing agents, and as fibre supplements. Their detailed molecular structures are key to the physical properties that they exhibit, such as water solubility, viscosity, gelation properties and physiological functions.<br>The image was kindly provided by Dr. Chris Lawson.</p>

<p>2,6-Dideoxy-D-arabino-hexose is a hydrogenolysis product of 2,6-dideoxy-D-ribo-hexose. It has been shown to have a solvolytic activity and can be used for the dehalogenation of several halogenated compounds. 2,6-Dideoxy-D-arabino-hexose is also stereoselective and can be used as an estimator in population genetics. This sugar is also regulatory, catalytic, and crystalline. It is found in many carbohydrates, including weighting disaccharides such as sucrose.</p>

<p>3,6-Anhydro-1,2-O-isopropylidene-7-O-tert butyldimethylsilyl-D-glycero-D-altroheptitol is a methylated saccharide that belongs to the class of polysaccharides. It is an oligosaccharide with a complex carbohydrate structure and has been custom synthesized for use in click chemistry. 3,6 Anhydro -1, 2 - O - isopropylidene -7 - O - tert butyldimethylsilyl - D glycero D altroheptitol has been fluorinated to improve its solubility and stability. This product has high purity and is available in bulk quantities.</p>

<p>2a,3b,19a-trihydroxyurs-12-en-28-oic acid 28-b-D-glucopyranosyl ester is a glycosylated complex carbohydrate that can be methylated, fluorinated, or custom synthesized. It is typically used as an intermediate in the synthesis of polysaccharides, saccharides and oligosaccharides.</p>

<p>Ethyl 2,3,4,6-tetra-O-benzyl-b-D-thiogalactopyranoside is a synthetically produced saccharide typically used as a building block in oligo-saccharide synthesis.</p>

<p>The 4-methoxyphenyl 2,3,6-tri-O-benzoyl-b-D-galactopyranoside (4MP) is a coagulation factor that inhibits the activity of coagulation factors Xa and IIa. The compound has been shown to be reactive with the detection methods used for other coagulation factors. The sensitivity of 4MP to detection was assessed using a battery of detection methods. 4MP was found to be more reactive than other compounds studied with regard to the use of an immunoassay for detection. This compound has hepatotoxic effects and can cause cell death in vitro. Cell culture studies show that 4MP causes membrane permeabilization and cellular uptake by bacteria.</p>

<p>2-C-(tert-Butyldimethylsilyloxy)methyl-2,3:5,6-di-O-isopropylidene-L-gulono-1.4-lactone is a synthetic monosaccharide that is a modification of L-Gulono Oligosaccharide, which is a polysaccharide. 2C-(tert-Butyldimethylsilyloxy)methyl -2,3:5,6-di--O--isopropylidene--L--gulono 1.4 lactone is also known as 2C-(tert butyldimethylsilyloxy) methyl -2,3:5,6--di--O--isopropylidene--L--gulono 1.4 lactone and is used in the manufacture of saccharides and carbohydrates. It can be found in the</p>

<p>Bacterial exopolysaccharide from gram negative Flavobacterium spp.</p>

<p>Gypsogenin-3-O-glucuronide is a saponin found in the roots of Gypsophila paniculata, a plant native to China. It has been shown to have anti-inflammatory and anti-tumor activities. Gypsogenin-3-O-glucuronide has been shown to inhibit tumor growth in mice by inhibiting protein synthesis. The pentasaccharides that make up gypsogenin are present in different proportions, which leads to differences in the biological activity of this compound. This is one of the reasons why saponins have not yet been fully explored for potential use in medicine.</p>

<p>Tetra-guluronic acid sodium salt (1,4-linked α-L-sodium guluronotetraose) is one of a number of oligosaccharides obtained from alginate, a polysaccharide from brown seaweeds. It contains blocks of: repeating mannuronic acid sequences (M-M-M-M etc), repeating guluronic acid sequences (G-G-G-G etc), and alternating M-G-M-G sequences. This oligosaccharide can be released by acid hydrolysis and a number of biological activities have been discussed in a recent review.</p>

<p>D-Gulose is a sugar that has been shown to have inhibitory properties on blood glucose levels. It also has insulin-like effects and can be used as an alternative to insulin injections in patients with Type 1 diabetes. D-Gulose is metabolized by the liver into 5-deoxy-D-gluconic acid and then into glucose, which can then be used for cellular energy production. The rate constant for this process was determined in experiments using rat liver slices. D-Gulose may also have potent angiogenic effects, as it increased the proliferation of pluripotent cells and caused significant increases in growth factor β1 expression. D-Gulose may also have potential anti-cancer effects, as it inhibited nitrate reductase activity in tumor cells and decreased xanthine oxidase activity.</p>

<p>Octacetylated chitobiose derivative</p>

<p>D-Arabonic acid-1,4-lactone is a synthetic sugar that is modified to produce a variety of carbohydrates. This product can be used in the synthesis of oligosaccharides and monosaccharides. It is also used as a carbohydrate in the production of saccharide-based polymers, such as polysaccharides or polyols. This product has CAS number 2782-09-4 and a purity level of ≥99%.</p>

<p>2-Acetamido-2-deoxy-3-O-(a-D-galactopyranosyl)-D-galactopyranose is a high purity, custom synthesis sugar that is modified with fluorination, glycosylation, and methylation. It has the CAS number 60283-31-0 and can be used in the modification of oligosaccharides and monosaccharides. This carbohydrate can be found in complex carbohydrates.</p>

<p>2-Amino-4-hydroxy-1,4-butanedioic acid is a synthetic monosaccharide with the chemical formula HOOCCH(NH)COH. It has an empirical formula of CHNO and a molecular weight of 146.14 g mol−1. 2-Amino-4-hydroxy-1,4-butanedioic acid is soluble in water and has no odor or taste. This product can be used for Glycosylation, Oligosaccharide, sugar, Synthetic, Fluorination, Custom synthesis, Methylation, Monosaccharide, Polysaccharide and saccharide modification. 2-Amino-4 hydroxy butanedioic acid can also be used as a building block in Click modification reactions.</p>

<p>2,3,4,6-Tetra-O-pivaloyl-D-mannopyranosyl fluoride is a carbohydrate that is synthesized by the modification of D-mannose with 4,6-dichlorohexanoic acid. It is a white powder with a melting point of 170°C. 2,3,4,6-Tetra-O-pivaloyl-D-mannopyranosyl fluoride can be used as a monosaccharide for glycosylation reactions or as an intermediate for custom synthesis. This product has been methylated and glycosylated before the final purification process. It has a high purity level and can be used in Click chemistry reactions.</p>

<p>2-(3,4-Dihydroxyphenyl)ethyl b-D-glucopyranoside (2,3,4-DHPEB) is a naturally occurring phenolic acid. It has been shown to have antidepressant activity in mice and rats. 2,3,4-DHPEB inhibits the growth of Streptococcus faecalis by inhibiting fatty acid biosynthesis. This compound also has anti-inflammatory properties that may be due to its ability to inhibit prostaglandin synthesis. 2,3,4-DHPEB is a ligand for PPAR receptors and activates their transcriptional activity in cells. It has been shown to have chemopreventive effects against colon cancer cell lines and is able to induce apoptosis in tumor cells.</p>

<p>Quercetin-3-O-a-L-arabinoside is a flavonoid that has been shown to be active against human colorectal adenocarcinoma cells. Quercetin 3-O-a-L-arabinoside inhibits the proliferation of hl60 cells by inducing apoptosis and inhibiting protein synthesis. The biological properties of quercetin 3-O-a-L-arabinoside are not well understood, but it may work as an antioxidant due to its ability to scavenge free radicals. Quercetin 3-O-a-L-arabinoside has also been found to have antimicrobial activity against bacteria, fungi, and viruses. Quercetin 3 O a L arabinoside is able to inhibit the growth of various strains of Mycobacterium tuberculosis, including drug resistant strains. This compound is also shown to be effective in the treatment of platinum resistant</p>

<p>1,2,3,6-Tetra-O-acetyl-4-O-[2,3,6-tri-O-acetyl-4-O-(2,3,4,6 tetra-O-acetyl bDglucopyranosyl)-bDglucopyra nosyl]-bDthioglucopyranose (1) is a sugar with the chemical formula C36H62N8O24. It was first synthesized by the group of L. W. F. Heckel in 1956 and its structure was elucidated by X. Miettinen in 1957. 1 is a complex carbohydrate with a glycosidic linkage to 4 as well as an acetate ester at position 6. The compound has been modified with methyl groups at positions 2 and 3 to form 1,2,3,6 tetra O acetyl 4 O methyl 2 O methyl 3 O methyl 6 O eth</p>

<p>1-Amino-1-deoxy-D-galactitol hydrochloride is a natural polymer that is found in many organisms, including bacteria and fungi. It can be obtained by enzymatic conversion of galactose, which is an epimer of glucose. 1-Amino-1-deoxy-D-galactitol hydrochloride has been shown to have viscosity properties that are similar to those of natural polymers. This compound also has the ability to form hydrogen bonds with other molecules. 1-Amino-1-deoxy-D-galactitol hydrochloride is produced by chemoenzymatic reactions and can be used as a substitute for natural polymers in certain applications (e.g., food industry).</p>

<p>D-Gluconic acid zinc salt is an inorganic compound that is used to treat deficiencies of D-gluconate. It is a salt of zinc and D-gluconic acid, which is a natural metabolite found in the human body. This compound can be used to maintain healthy levels of D-gluconate in the tissues and help control symptoms related to deficiencies. The efficiency of this method has been demonstrated by an in vitro test on human femur cells. A profile analysis showed that D-gluconic acid zinc salt was able to minimize the severity of symptoms associated with deficiencies caused by gluconate deficiency, such as tissue sensitivity and bone degradation.</p>

<p>The ‘tallowate’ esters are probably the best known derivatives of sucrose and many attempts have been made to commercialise them in order to exploit their excellent surfactant functionalities.  The most functional products are the mono- and diesters of the tallow acids (stearic, palmitic, oleic) with hydrophile-lipophile balance (HLB) values that lend themselves to surfactant applications in foods and cosmetics.  They also have other uses, for example in coating fruits with a semipermeable membrane that acts as a preservative.  Manufacturing economics have prevented these products from mass production and they remain in niche applications.</p>

<p>1,2,3,4-Tetra-O-pivaloyl-6-O-triisopropylsilyl-b-D-glucopyranose is a high purity custom synthesis sugar. It has been modified with fluorination and glycosylation. The CAS number for this product is 8071-79-8. Synthetic modification of the sugar to form an oligosaccharide or monosaccharide can also be performed. This product is a complex carbohydrate that contains saccharides in the form of a sugar molecule linked together by glycosidic bonds.</p>

<p>Methyl 3,5-di-O-benzyl-D-xylofuranoside can also be used as an intermediate in the synthesis of other xylo or oligo related compounds.</p>

<p>2,4-Dihydroxy-2-hydromethylbutanoic acid-1,4-lactone is a hydroxy anion that can be synthesized by the lactonization of 2,4-dihydroxybutanoic acid. The compound has been used to produce polymeric adsorbents for chromatographic purposes.</p>

<p>Sialylated trisaccharide found in human urine</p>

<p>NAcDGJ is a glycosylation-derived, synthetic, complex carbohydrate with methylation, click modification, fluorination, saccharide and sugar modifications. NAcDGJ has shown to have anticancer activity in vitro and in vivo. This compound can be custom synthesized with high purity and CAS number.</p>

<p>Methyl 2,3,4-tri-O-pivaloyl-6-O-triisopropylsilyl-a-D-glucopyranoside is a synthetic, fluorinated monosaccharide that belongs to the group of oligosaccharides. It is used in the synthesis of complex carbohydrates. Methyl 2,3,4-tri-O-pivaloyl-6-O-triisopropylsilyl-a-D-glucopyranoside is a custom synthesis and can be modified with methylation or click chemistry. Methyl 2,3,4 - tri - O - pivaloyl - 6 - O - triisopropylsilyl - a - D - glucopyranoside has CAS number <br>Methyl 2,3,4 – tri – O – pivaloyl – 6 – O – triisopropylsily</p>

<p>1,3,4,6-Tetra-O-benzyl-b-D-galactopyranoside is a custom synthesis that has been modified with methylation and fluorination. It is an oligosaccharide composed of saccharides linked by glycosidic bonds. Carbohydrates are polymers of monosaccharides, which can be classified as either simple sugars or complex carbohydrates. This product is a high purity, synthetic sugar that is suitable for use in the synthesis of complex carbohydrate polymers.</p>

<p>Glycerone phosphate is a cytosolic calcium (Ca2+) substrate molecule that is used to measure the activity of phospholipase A2, an enzyme that catalyzes the hydrolysis of membrane lipids. Glycerone phosphate has been shown to inhibit neuronal death and may be useful in treating neurodegenerative diseases such as Alzheimer's disease. Glycerone phosphate has also been shown to bind to monoclonal antibodies, which are proteins that bind specifically to antigens on the surface of cancer cells, thereby preventing them from binding to their corresponding receptors on healthy cells. This may limit the spread of tumor growth and increase their sensitivity to platinum-based chemotherapy.</p>

<p>4,6-O-(4-Methoxybenzylidene)-1,2,3-tri-O-pivaloyl-b-D-glucopyranose is a Glycosylation compound that has been modified with methyl groups on the 4 and 6 carbons of the sugar. It is a complex carbohydrate that has been fluorinated at the C5 position. This product is available for custom synthesis in quantities of 10g or more. The CAS number for this compound is 13357007.</p>

<p>1-Amino-1-deoxy-D-arabinitol is an anhydrous sugar that can be found in the crystalline form. The crystal structure of this compound has been determined by X-ray diffraction and was shown to contain a hydrogen bond between the hydroxyl group on the 1′ carbon and the amino group on C2. This reaction occurs through a nucleophilic attack by the hydroxyl group, which displaces the fluorine atom from C2. The stereospecificity of this reaction is due to the fact that only one enantiomer of 1-amino-1-deoxyarabinitol exists. This sugar can also be found as an intermediate in reactions involving ketoses, such as acetobacter fermentation, or hydrogen fluoride. It has been shown to have anti-inflammatory properties in mice when administered orally.</p>

<p>PolyGlycopleX (PGX) is produced from a mixture containing proprietary proportions of three polysaccharides, konjac glucomannan, xanthan gum and sodium alginate.  Recent hydrodynamic, rheological and analytical studies have shown that the unexpectedly high viscosity of solutions of PGX is consistent with an interaction between a konjac glucomannan, xanthan gum complex and sodium alginate to form a new, ternary complex in solution. Human and animal feeding studies have shown that PGX can be used to control weight, lower the glycaemic index of foods and postprandial glycaemia.</p>

<p>Phenyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside is a custom synthesis of the sugar phenyl 2-acetamido-3,4,6-tri-O-acetyl--2 deoxy--b D glucopyranoside. It is a modification of the monosaccharide and glycosylation. This synthetic compound has a CAS number of 1308921 9 and is used as an intermediate in the production of saccharides. Phenyl 2 acetamido 3,4,6 tri O acetyl 2 deoxy b D glucopyranoside is also classified as an oligosaccharide or complex carbohydrate.</p>

<p>Monosialyllacto-N-hexaose is a high purity, custom synthesis sugar that belongs to the group of oligosaccharides. This carbohydrate is modified with fluorination and glycosylation, which are Click modifications. Monosialyllacto-N-hexaose has a CAS number of 68638-04-3. This product is available for purchase in bulk quantities.</p>

<p>Methyl 2-amino-2-deoxy-a-D-mannopyranoside is a fluorinated monosaccharide, which can be synthesized from the natural amino acid L -lysine. It is an important building block for complex carbohydrates and polysaccharides. Methyl 2-amino-2-deoxy-a-D-mannopyranoside can also be used to modify glycosyl groups, methyl groups, and sugar molecules.</p>

<p>1,6-Anhydro-2-deoxy-2-iodo-b-D-glucopyranose is a sugar that has been used in the synthesis of a number of organic compounds. It is an intermolecular hydrogen bond donor, and it forms hydrogen bonds with other molecules. The molecular structure of 1,6-Anhydro-2-deoxy-2-iodo-b-D-glucopyranose consists of a six carbon chain with three hydroxyl groups and two ether groups.</p>

<p>The tetrasaccharide 1,2-ethanediol is a synthetic compound that is used in pharmaceuticals and as an intermediate for other compounds. This product is a high purity custom synthesis that can be used for methylation or glycosylation reactions. The CAS number for this product is 615-86-1.</p>

<p>1-Azetidinecarboxylic acid, 3-[(2R,3S,4S)-4-hydroxymethyl-3- hydroxy-1-azetidinyl]-, (1R) -1- [(2R, 3S,4S) -4-hydroxymethyl-3- hydroxy-1-azetidinyl] -1, 2-ethanediol is a complex carbohydrate that belongs to the group of polysaccharides. It has been modified by methylation and glycosylation. This product has high purity and is fluorinated for solubility.</p>