Acides cinnamiques

Applications BENZYL CINNAMATE (cas# 103-41-3) is a useful research chemical.

Applications Isoamyl 4-Methoxycinnamate is used in the highly protective sunscreen composition against the UVA/UVB.
References Cuderman, P., et al: Anal. Bioanal. Chem., 387, 1343 (2007), Zhao, X., et al.: Environ. Sci. Technol., 42, 1201 (2008), Dubrovski, P., et al.: Text Res. J., 79, 351 (2009),

Applications trans-p-Coumaric Acid is the E-isomer of p-Coumaric Acid (C755365), a hydroxy derivative of Cinnamic Acid with antioxidant properties. p-Coumaric acid is a is a major component of lignocellulose. Studies suggest that p-Coumaric Acid may reduce the risk of cancer by reducing the formation of carcinogenic nitrosamines.
References Kikugawa, K. et al.: J. Agric. Food Chem., 1, 780 (1983); Ferguson, L.R. et al.: Mol. Nutrit. Food Res., 585 (2005); Chung, F.L. et al.: IARC Sci. Pub., 57, 797 (1984);

3,5-Dihydroxycinnamic acid is a metabolite of the amino acid tyrosine and an intermediate in the biosynthesis of phenylalanine. It has been shown to have anti-inflammatory properties that may be due to its ability to inhibit prostaglandin synthesis. 3,5-Dihydroxycinnamic acid has also been identified as a carcinogen and is associated with an increased risk of cancer in women. 3,5-Dihydroxycinnamic acid is found in urine samples at concentrations between 2 and 10 µmol/L.

Caffeic acid is naturally produced by the metabolism of plants and fungi. Caffeic acid has an antioxidant activity that can be higher than tocopherol in oil-in-water emulsions. Caffeic acid has proven antimicrobial activity against Staphylococcus aureus. In mice, caffeic acid inhibits the enzyme 5-lipoxygenase thus inhibititing the biosynthesis of the inflammatory mediators leukotrienes.

Cis-4-Chloro-3-nitrocinnamic acid is an aromatic organic compound with potential utility in biochemical research and synthesis. This compound is typically derived from synthetic chemical processes involving chlorination and nitration reactions on cinnamic acid derivatives. Its molecular structure, characterized by both chloro and nitro functional groups, allows it to interact in unique ways with various biochemical pathways and molecular frameworks.

Ferulic acid is a plant polyphenol that has been shown to induce apoptosis in human leukemia cells and inhibit the production of tumor necrosis factor-α (TNF-α), thereby improving glucose tolerance. Ferulic acid inhibits the mitochondrial membrane potential by binding to the Mcl-1 protein and inducing its degradation, leading to anion radical scavenging. This compound also has significant cytotoxicity in a model system and has been shown to have hypoglycemic effects in animal studies. Ferulic acid also induces cell cycle arrest by inhibiting the expression of cyclin D1, which is involved in regulating the G1 phase of the cell cycle.

Trans-4-nitrocinnamic acid is an organic compound that is synthesized from 4-hydroxycinnamic acid by nitration with aqueous or alcoholic nitric acid. Trans-4-Nitrocinnamic acid has been shown to inhibit tyrosinase activity in the presence of metal hydroxides, such as copper, zinc, and iron. The reaction mechanism is unclear but may involve an initial protonation of the phenolic group followed by an electron transfer to the nitro group. This reaction results in an irreversible inhibition of tyrosinase activity. Trans-4-Nitrocinnamic acid also reacts with hydrochloric acid to produce a carboxylate salt that can be used for sample preparation.

Cis-4-Hydroxycinnamic acid is a phenolic acid that is found in plants and is a natural compound. It has been shown to be an inhibitor of cell proliferation. Cis-4-Hydoxycinnamic acid inhibits the synthesis of DNA and RNA, which may inhibit the growth of bacteria and fungi. This compound can be extracted from plant materials by acetate extract or preparative high-performance liquid chromatography (HPLC). Cis-4-Hydoxycinnamic acid also has anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.

4-Aminocinnamic acid is a monomer that can be polymerized to form polymers. It is soluble in organic solvents and is resistant to UV light. 4-Aminocinnamic acid has been shown to have photochemical properties and can be used to produce hydrogen bonds with other molecules. This compound has been used as a carbon source for microbial growth and has been shown to be an effective genetic control agent for the bacteria Escherichia coli. 4-Aminocinnamic acid has also been shown to inhibit the growth of butyric acid producing bacteria, such as Clostridium butyricum, while promoting the growth of lactic acid producing bacteria, such as Lactobacillus plantarum.