Glucides et Glycoconjugués

<p>Stability Hygroscopic, Light Sensitive, Temperature Sensitive<br>Applications An intermediate in the Maillard reaction of proteins with glucose, which is metabolised to 3-Deoxyfructose. An intermediate in the formation of pyrraline, which might contribute to a pathological effect, such as carcinogenesis.<br>References Kato, H. et al.: Agric. Biol. Chem., 51, 683 (1987), Hayase, F. et al.: J. Biol. Chem., 264, 3758 (1989), Kato, H. et al.: Biochimica et Biophysica Acta, 1035, 71 (1990)<br></p>

<p>Applications Citric Acid Monohydrate is a useful buffer component for antigen and epitope unmasking.<br></p>

<p>Applications Lauramine Oxide, is an frequently-used amine oxide surfactant. It is strongly hydrophilic , and it forms normal micelles and normal liquid crystalline phases.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kocherbitov, v., et al.: J. Molec. Struct.: Theochem., 808, 111 (2007); Kocherbitov, v., et al.: J. Phys. Chem. B., 110 (27), 13649 (2006);<br></p>

<p>Applications Contained in tobacco flavor additives.<br>References Sumoto, K., et al.: Chem. Pharm. Bull., 39, 792 (1991), Shimamura, T., et al.: Biosci., Biotechnol., Biochem., 67, 295 (2003),<br></p>

<p>Stability Store in freezer<br>Applications Prepared by acetolysis of chitin. Studies have shown this compound to have anti tumor effects.<br>References Barker, S.A., et al.: J. Chem. Soc., 2218 (1958); Suzuki, K., et al.: Carbohydrate Research, 151, 403 (1986)<br></p>

<p>Applications D-Glucosaminic Acid is a useful starting material for the synthesis of aldonic acids containing a free carboxyl group and having all hydroxyl functions esterified with a simple carboxylic acid are well established deriviatives.<br>References Major, R.T., et al.: J.A.C.S., 58, 2474 (1936), Hurd, C.D., et al.: J.A.C.S., 60, 235 (1938), Wolfrom, M., et al.: J.A.C.S., 61, 574 (1939)<br></p>

<p>Applications trans-4-[[(2-Amino-5-bromophenyl)methyl]amino]-cyclohexanol is an impurity of Ambroxol (A575900), a bronchosecretolytic drug and a metabolite of Bromohexine.<br>References Jauch, R., et al.: Arzneim-Forsch., 13, 474 (1963)<br></p>

<p>Applications 6-O-β-D-Galactopyranosyl-D-galactose can be as a substrate of β-galactosidase in research studies.<br>References Kotake, T., et al.: Plant Physio., 138(3), 1563-1576 (2005)<br></p>

<p>Applications Useful for the synthesis of Biocytin containing peptides to study the mechanism of reactions catalyzed by biotin - containing enzymes.<br>References Bodanszky, M., and Fagan, D.T.: J. Am. Chem. Soc., 99, 235 (1977)<br></p>

<p>Stability Very Hygroscopic<br>Applications 4-Nitrophenyl 3-O-(α-D-Mannopyranosyl)-α-D-mannopyranoside (cas# 93979-06-7) is a compound useful in organic synthesis.<br></p>

<p>Applications Xylobiose is a disaccharide that can reduce the blood sugar and blood fat and inhibit the fat accumulation of diet-induced obese rats.<br>References Chen, H., et al.: Shipin Kexue, 35, 255 (2014)<br></p>

<p>Applications A Vitamin D derivative.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Koeffler, M.R., et al.: Blood, 74, 82 (1989),<br></p>

<p>Applications rac FTY720 is a sphingosine 1-phosphate receptor modular, ameliorates experimental autoimmune encephalomyelitis by inhibition of T cell infiltration.<br>References Igarashi, J., et al.: J. Biol. Chem., 275, 32363 (2000), Bandhuvula, P., et al.: J. Biol. Chem., 280, 33697 (2005),<br></p>

<p>Stability Very Hygroscopic<br>Applications CDPcholine cholinephosphotransferase analog.<br>References Kennedy, E.P., et al.: J. Biol. Chem.,222,185 (1956),<br></p>

<p>Applications Cytidine 5’-Phosphate Methyl Ester Sodium Salt is an byproduct formed in the synthesis of analogs of Cytidine 5’-Diphosphate with an important role in the metabolism of phospholipids.<br>References Trotter, P., et al.: J. Biol. Chem., 270, 6062 (1995), Janssen, M., et al.: Yeast, 16, 641 (2000), Henneberry, A., et al.: Mol. Biol. Cell, 12, 511 (2001), Boumann, H., et al.: Biochemistry, 42, 3054 (2003),<br></p>

<p>Applications Citric Acid-13C6 is an isotope labelled compound of citric acid (C521000). Citric acid is mainly used as an acidifier, flavoring agent and chelating agent. Citric acid is also a metabolite of Dimethyl Fumarate (D464965), a compound used as a treatment for the relapsing forms of multiple sclerosis and psoriasis.<br>References Dawson, R.M., et al.: Data for Biochem. Rsch., (1959); Gruber, C. M., et al.: J. Pharmacol. Exp. Ther., 94, 65 (1948); Lofty, W.A., et al.: Bioresource. Tech., 98, 3470 (2007); Schimrigk, S., et al.: Eur. J. Neurol., 13, 604 (2006)<br></p>

<p>Applications Monoglycerides fatty acid esters are useful for improvement of texture and flavor of beverages. 93% 1-Oleoyl, 7% 2-oleoyl.<br>References Lee, T.-H., et al.: J. Nat. Prod., 72, 1960 (2009),<br></p>

<p>Applications An Amadori compound having the potential to alter cellular adhesion, inhibit cancer metastasis and induce apoptosis.<br>References Horiuchi, T., et al.: Agric. Biol. Chem., 55, 333 (1991), Sosnovsky, G., et al.: J. Pharm. Sci., 82, 649 (1993), Glinsky, G., et al.: Cancer Res., 56, 5319 (1996),<br></p>

<p>Applications Thymidine-alpha,alpha,alpha,6-d4 (CAS# 347841-67-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications D-(-)-Tartaric Acid the synthetic enantiomer of L-(+)-Tartaric Acid (T007630), used in the preparation of synthetic analgesics.<br>References Van Bever, W. et al.: J. Med. Chem., 17, 1047 (1974);<br></p>

<p>Stability Temperature Sensitive<br>Applications A metabolite of Shikimic Acid.<br>References Lauhon, C.T. and Bartlett, P.A.: Biochemistry, 33, 14100 (1994), Balasubramanian, S., et al.: Biochemistry, 34, 341 (1995),<br></p>

<p>Applications Xylotetrose is a xylose oligomer that is of interest to many fields of study and is an intermediate reaction product of the hydrolysis of hemicelluloses.<br>References Bunnell, K., et al.: J. Liq. Chromatogr. R. T., 38, 801 (2015)<br></p>

<p>Applications Labelled 2-Oleoylglycerol (O528020). A metabolite of 2-acylglycerol used as biomarker.<br>References Owen, M., et al.: Biochem. J., 323, 17 (1997), Waterman, I., et al.: J. Lipid Res., 43, 1555 (2002), Chon, S., et al.: J. Biol. Chem., 282, 33346 (2007),<br></p>

<p>Impurity Biotin EP Impurity B<br>Applications Biotin Diacid (Biotin EP Impurity B) is an impurity of Biotin (B389040).<br>References Trotter, J., et al.: Biochemistry, 5, 713 (1966), Suurkuusk, J., et al.: Eur. J.Biochem., 28, 438 (1972),<br></p>

<p>Stability Very Hygrocsopic<br>Applications A labile hydrolysis product of the antitumor nuceloside 5-Azacytidine (A796000).<br>References Beisler, J. A. et al.: J. Med. Chem., 21, 204 (1978); Chan, K.K. et al.: J. Pharmac. Sci., 68, 807 (1979);<br></p>

<p>Applications L-Thioproline is used to create a monolayer on gold electrodes for the determination Copper(II). L-Thioproline has shown to be an effect inhibitor of proline absorption in Saccharomyces chevalieri.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cui, X., et. al.: Sci. China Chem., 53, 257 (2010); Magana-Schwenchke, N., Schwencke, J.: BBA-Biomembranes, 173, 313 (1969)<br></p>

<p>Applications A labelled metabolite of Bromohexine. Ambroxol Hydrochloride is a bronchosecretolytic drug.<br>References Jauch, R., et al.: Arzneim-Forsch., 13, 474 (1963)<br></p>

<p>Applications An impurity found in fingolimod (F805000).<br></p>

<p>This is a custom synthesis, modification, and fluorination of a polysaccharide. The monosaccharide units are methylated and then modified with a click reaction. The saccharides are glycosylated with 2-O-a-D-mannopyranosyl moieties for the purpose of increasing their water solubility. This saccharide has been synthesized by the modification of an oligosaccharide that has been modified to include a hydroxyl group. The carbohydrate is complex and contains many different types of sugars including glucose, mannose, and galactose.</p>

<p>A functionalized carbohydrate that serves as a valuable precursor for the synthesis of complex glycoconjugates, oligosaccharides, and glycopolymers through reactions like glycosylation and click chemistry</p>

<p>Zymosan is prepared from the cell walls of baker's yeast (Saccharomyces cerevisiae) and consists of polysaccharide chains of various molecular weights, containing approximately 73% polysaccharide, 15% protein, 7% lipid and other inorganic components. When injected into animals, it induces inflammation and has been used for many years in inflammation and immunology research. The conditions activated include components of the complement system, prostaglandins and leukotrienes, platelet aggregation factor, and lysosomal enzymes. Zymosan preparations are often insoluble but can be made soluble for separation on DE cellulose or Sepharose to produce more active fractions.</p>

<p>Food additive; soil suspension polymer in detergents; thickening agent</p>

<p>4-Methoxyphenyl 3,4-di-O-benzyl-2,6-di-O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-b-D-glucopyranosyl)-a-D -mannopyranoside is a synthetic glycoside that can be custom synthesized to order. It is considered to be of high purity with a CAS number 58314−10−1. This product has been fluorinated and glycosylated and is synthetically produced. 4MPBP has the following modifications: methylation, modification, and glycosylation. 4MPBP is an oligosaccharide that is composed of saccharides and a complex carbohydrate.</p>

<p>3-O-(b-D-Galactopyranosyl)-D-mannopyranose is a synthetic sugar that is modified with fluorine at the C-3 position. It is a member of the carbohydrate family and has been shown to be useful for glycosylation or click chemistry. 3-O-(b-D-Galactopyranosyl)-D-mannopyranose can be custom synthesized to meet your needs. This product also features high purity and methylation, which makes it an excellent candidate for synthesis projects. This product can be used in research applications, such as complex carbohydrate modification, glycosylation, or click chemistry.</p>

<p>2-Acetamido-4-O-{2-acetamido-4-O-[3-O-[2,4-di-O-(2-acetamido-2,6-dideoxyb -D-glucopyranosyl)-a,D -mannopyranosyl]-6-O-[2,6 -di(2 -acetamido)-b -D -glucopyranosyl]-b D mannopyranosyl]] b D mannopyranosyl} 2,6 dideoxy b D glucopyranosyl} 6 O-(a L fucopyranosyl)}</p>

<p>Mixed DP 7/8 Na galacturonans (α-1,4 galacturonoheptoses and octaoses), are derived from pectin or pectic acid, by enzymatic or partial acid hydrolysis. They are used in galacturonic acid metabolism research as a substrate to identify, differentiate, and characterized endo- and exopolygalacturonase(s), and gluconase(s). The addition of very short fragments of homogalacturonan oligosaccharides, restores development in dark-grown, de-etiolated seedling mutants, suggesting that they are unable to generate de-methylesterified pectin fragments. A model of spatiotemporally separated photoreceptive and signal-responsive cell types has been proposed, that contains overlapping subsets of the regulatory network of light-dependent seedling development.</p>

<p>GalNAca1-3Galb1-3GalNAc</p>

<p>2,3,6-Tri-O-acetyl-4-O-(2,3,6-tri-O-acetyl-4-O-[(2,3,4,6-tetra-O-acetyl bDgalactopyranosyl)]bDglucopyranosyl)-aDglucopyranosyldimethyl bromide is a synthetic sugar that is used as a building block for the synthesis of glycosides. This monosaccharide has been modified using click chemistry to obtain a methylated form that can be used in the synthesis of oligosaccharides and polysaccharides. It is also used to produce an acetal derivative that can be used in the synthesis of glycosidic linkages.</p>

<p>Hexaacetylchitohexaose is a hexamer of N-acetylgucosamine subunits which are linked by β-(1,4)-glucosidic bonds. N-acetylgucosamine is the monomeric unit of the natural polymer chitin which is degraded by chitinases, in mammals, to form smaller fragments that can induce an immune response. Like chitin and some of its derivatives, hexaacetylchitohexaose is a substrate of lysozymes. Hexaacetylchitohexaose has been shown to significantly inhibit tumour growth in mice by the activation of innate and adaptive immune cells.</p>

<p>4-O-(2,3,4,6-Tetra-O-acetyl-b-D-glucopyranosyl)-1,2,3,6-tetra-O-acetyl-b-D-thioglucopyranose is a glycosylated saccharide that belongs to the group of complex carbohydrates. The glycosylation of 4-O-(2,3,4,6,-Tetra-O-acetyl b -D -glucopyranosyl)-1,2,3,6,-tetra -O -acetyl b -D -thioglucopyranose is achieved by the enzymatic reaction of an acetate donor and an acceptor molecule in the presence of glucose 1 phosphate (G1P) and UDP sugar pyrophosphorylase. It has been modified by methylation with dimethyl sulphate in the presence of</p>

<p>Inhibitor that targets cellulase enzymes engaged in the degradation of cellulose.</p>