Composés et métabolites pharmaceutiques et vétérinaires

<p>5-Methoxy-5-oxopentanoic acid (mono-Methyl glutarate) is a metabolite of dibasic esters(DBEs) by nasal respiratory and olfactory mucosae.</p>

<p>Transcrocetin (8,8'-Diapocarotenedioic Acid) is a singlet oxygen quencher.</p>

<p>Methylglutaric acid, a leucine byproduct, is linked to two metabolic disorders, detected in patient urine.</p>

<p>Malic acid reduces L. monocytogenes in poultry and may help treat calcium kidney stones.</p>

<p>5-Hydroxytryptamine creatinine sulfate monohydrate (Serotonin creatinine sulfate monohydrate) is a neurotransmitter.</p>

<p>Zinc Protoporphyrin is an oral HO-1 inhibitor that reduces PG's protection against H2O2 and has anti-cancer properties.</p>

<p>Norbenzetimide, an organic compound, is prepared from benzetimide by catalytic transfer hydrogenolysis.</p>

<p>2-METHYLVALERIC ACID is a natural product.</p>

<p>Tyrosol (2-(4-Hydroxyphenyl)ethanol) is a phenolic antioxidant that is naturally present in several foods such as wines and green tea and is present most</p>

<p>ATP disodium salt hydrate (Adenosine disodium triphosphate) is a nucleoside triphosphate used in cells as a coenzyme.</p>

<p>DL-Homocysteine (2-Amino-4-mercaptobutyric acid) is a potential marker for tumor cell growth.</p>

<p>1,4-D-Gulonolactone, precursor to vitamin C, is an enzyme substrate linked to oxidative stress and absent in scurvy-susceptible species.</p>

<p>Miquelianin (Quercetin 3-glucuronide) is a potent stilbene oxidase inhibitor, it has antioxidant, anti-atherogenic, and anti-inflammatory activities.</p>

<p>β-nicotinamide mononucleotide (NMN) is a natural nucleotide and a key intermediate in the synthesis of coenzyme I (NAD+). Cost effective and quality assured.</p>

<p>Petroselinic acid (5-Heptadecylene-1-carboxylic acid) is a monounsaturated omega-12 fatty acid found naturally in plant and animal oils and fats.</p>

<p>Ethoxyacetic acid is an endogenous metabolite of ethylene glycol monoethyl ether acetate.</p>

<p>Betulin (betulinol) (lup-20(29)-ene-3β, 28-diol) is an abundant, naturally occurring triterpene.</p>

<p>Histidine (H) is a charged, polar alpha-amino acid, essential in protein synthesis and active in enzyme sites. Its synthesis links to nucleotide pathways.</p>

<p>D-Desthiobiotin, a biotin derivative for affinity/protein chromatography, cell labeling, and separation.</p>

<p>3-demethylcolchicine is a natural product isolated from Gloriosa superba.Inhibitory effect on the polymerization of purified bovine brain tubulin.</p>

<p>H-HoArg-OH, a homologue arginine, is a strong inhibitor of human liver and bone alkaline phosphatase.</p>

<p>Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit.</p>

<p>Nicotinuric acid: a minor acyl glycine metabolite of fatty acids, synthesized by glycine N-acyltransferase.</p>

<p>5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA.</p>

<p>Calcifediol (U 32070E) is a natural product derived from the metabolism of vitamin D3 in the liver, a VDR ligand. Cost effective and quality assured.</p>

<p>H-Tyr(3-I)-OH (3-Iodo-L-tyrosine) is an inhibitor of tyrosine hydroxylase (Ki = 0.39 M) and an intermediate in the synthesis of thyroid hormones</p>

<p>Nerolidol (Peruviol) shows sedative effects in animals, oxidative process plays a crucial role on neuronal pathological consequence.</p>

<p>4-Methoxybenzoic acid could be used as raw material in cosmetic and dermatologic products, it has antiinflammatory and antimicrobial activities.</p>

<p>Isorhamnetin (3-methylquercetin) is the methylated metabolite of quercetin.</p>

<p>N-Acetylornithine is found in human blood plasma (avg. 1.1±0.4 μmol/L) and urine (~1 μmol/day).</p>

<p>Succinyl phosphonate trisodium salt is an inhibitor of α-ketoglutarate dehydrogenase (KGDHC)</p>

<p>Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.</p>

<p>Tomatidine serves as an anti-inflammatory agent by inhibiting NF-κB and JNK signaling pathways.</p>

<p>AMP is a purine nucleotide, vital in cell signaling and energy regulation, and inhibits EC 3.1.3.11 and 3.1.3.1, also an A1 receptor agonist.</p>

<p>L-Cysteine HCl hydrate: precursor to H2S, taurine, glutathione; suppresses ghrelin, reducing appetite.</p>

<p>N-Methylsarcosine improves athletic performance, boosts immunity, treats autism/epilepsy, tracks COPD, and aids in ionic liquid development.</p>

<p>3-Amino-4-hydroxybenzoic acid (3-amino-4-hydroxybenzenecarboxylic acid) is a useful research chemical.</p>

<p>β-Caryophyllene ((-)-(E)-Caryophyllene) acts as an CB2 receptor agonist.</p>

<p>L-Ascorbic acid sodium salt (Vitamin C sodium salt) is a more bioavailable form of vitamin C that is an alternative to taking ascorbic acid as a supplement.</p>

<p>Sodium Demethylcantharidate (Sodium norcantharidin) is extracted from Mylabris phqlarata pallas and has potent antitumor activity.</p>

<p>Sarsasapogenin (Parigenin) is a steroidal sapogenin, that is the aglycosidic portion of a plant saponin.</p>

<p>GHK-Cu is a copper complex with the peptide glycyl-L-histidyl-L-lysine, found in human plasma, saliva, and urine.</p>

<p>3-Methyl-2-oxobutanoic acid: neurotoxin byproduct of amino acid breakdown; causes metabolic acidosis.</p>

<p>H-HomoArg-OH.HCl (L-Homoarginine hydrochloride) is a specific inhibitor of liver-type alkaline phosphatase.</p>

<p>DL-O-Phosphoserine (DL-SOP), a normal metabolite in human biofluid, is an ester of serine and phosphoric acid.</p>

<p>H-Val-Ala-OH, a metabolite, is a dipeptide of L-Valine and L-Alanine.</p>

<p>Orotic acid zinc (Zinc Orotate) salt dihydrate is an intermediate product in pyrimidine synthesis.</p>

<p>L-Carnosine is an antioxidant found in muscles and brain, may slow aging-related biochemical changes.</p>

<p>Isoalantolactone (Isohelenin), isolated from Inula spp., can inhibit the growth of several types of Y cells.</p>

<p>L-Alanine (L-2-Aminopropionic acid) is an Amino Acid. Alanine is involved in the metabolism of tryptophan and vitamin pyridoxine.</p>

<p>N4-Acetylcytidine: a nucleoside from tRNA degradation, urinary marker for colorectal cancer.</p>

<p>3-Amino-2-oxazolidinone (AOZ) is the metabolite of Furazolidone. It is always be detected as a indicator of furazolidone residues in vivo.</p>

<p>L-Threonine is an essential amino acid for human nervous system, metabolism, liver health, digestion support, and can ease anxiety.</p>

<p>2-Methylacetophenone is a human endogenous metabolite.</p>

<p>(Z)-Aconitic acid is the cis-isomer of Aconitic acid.is an intermediate in the tricarboxylic acid cycle produced by the dehydration of citric acid.</p>

<p>Vardenafil hydrochloride is a New Phosphodiesterase Type 5(PDE5) Inhibitor, in the Treatment of Erectile Dysfunction in Men With Diabetes</p>

<p>Indole-3-carbinol (I3C), a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB and IκBα kinase</p>

<p>Alkaline phosphatase is a membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters under alkaline conditions. High-Quality, Low-Cost!</p>

<p>Formamide detects DMF exposure in workers, linked to prostate cancer risk.</p>

<p>Orotic acid monohydrate is an intermediate product in pyrimidine metabolism.</p>

<p>α-Pyridone (2-Hydroxypyridine)e is a catalyst for generating β-oxopropyl carbonates from cyclic carbonates and alcohols and in aminolysis of a polyglutamate.</p>

<p>2,2-Dihydroxyacetic acid (Formylformic acid) is an organic compound that is both an aldehyde and a carboxylic acid, is associated with primary hyperoxaluria.</p>

<p>Creosol is an agent of Antioxidant and Antibacterial.</p>

<p>Glycochenodeoxycholic Acid (Lithocholylglycine) is a glycine conjugate of lithocholic acid, a bile acid.</p>

<p>2-Phenylglycine (DL-α-Phenylglycine) is a metabolite in breast milk during the lactation period.</p>

<p>Pharmatose DCL 14 (D-Lactose monohydrate) is the major sugar present in milk and the main source of energy supplied to the newborn mammalian in mother's milk.</p>

<p>DPPC (129Y83) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes.</p>

<p>4-Methylbiphenyl (4-Phenyltoluene) is a human endogenous metabolite.</p>

<p>N-Methylhydantoin, a low-weight polar compound, degrades from creatinine and metabolizes from dupracetam in humans.</p>

<p>3-Indoleacetic acid sodium is a natural auxin hormone promoting growth; high levels can inhibit it, leading to its use as a herbicide.</p>

<p>Lauric Acid (Dodecylic acid),which is found naturally in plant and animal fats and oils, is a saturated medium-chain fatty acid with a 12-carbon backbone.</p>

<p>Scyllo-Inositol (Scyllitol) is one of the inositol stereoisomers, rare in the nature, and expected as a promising disease-modifying therapeutic agent for</p>

<p>Guanidinoethyl sulfonate (Taurocyamine) is a competitive glycine receptor antagonist.</p>

<p>(±)-Leucine (DL-2-Aminmo-4-methylvalerianic acid) can be found in Green bell peppers, Green zucchinis, Italian sweet red peppers, and Red bell peppers.</p>

<p>p,p'-DDE (p,p'-dichlorodiphenyldichloroethylene) is a metabolite and degradation product of the organochlorine pesticide DDT</p>

<p>RGX-202 (β-GPA) is an orally active inhibitor of the SLC6A8 transport protein. RGX-202 is a creatine analog that alters skeletal muscle energy expenditure.</p>

<p>Monobenzyl phthalate (Phthalic Acid Monobenzyl Ester) is Phthalate metabolite.</p>

<p>Homogentisic acid: antioxidant with anti-radical effects, protects against thermal cholesterol damage, melanin precursor, and Pfnek-1 inhibitor.</p>

<p>Canthaxanthin (E 161g) is a red-orange carotenoid that belongs to the xanthophyll group.</p>

<p>Norathiol (N-methyl-N-dithiocarboxyglucamine) is a metal chelator that promotes the excretion of 109Cd and may be used in the treatment of cadmium poisoning.</p>

<p>Vardenafil (Vivanza) is an oral therapy for the treatment of erectile dysfunction.</p>

<p>Estrone sulfate sodium, an inactive estrogen ester, transforms into estrone via steroid sulfatase. It's studied for targeting polypeptide transporters.</p>

<p>"(S)-(−)-Perillyl alcohol, a lavender monoterpene, inhibits Ras farnesylation, promotes apoptosis, and has anti-cancer effects."</p>

<p>3-Hydroxybutyric acid sodium (β-Hydroxybutyric acid sodium) is a metabolite present in type I diabetic patients that has the property of regulating membrane</p>

<p>(±)-1,2-Propanediol (Methyl ethyl glycol) is an aliphatic alcohol that is frequently used as an excipient to improve solubility and stability of drugs.</p>

<p>Ramiprilat is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.</p>

<p>Methionine (D-Methionine) (MRX-1024; D-Methionine) is an effective chemoprotective agent which can also inhibit the neuronal activity through GABAA receptor</p>

<p>Oleamide (Oleic acid amide) is an endogenous fatty acid amide and can be used in the synthesis of de novo in the mammalian nervous system.</p>

<p>(+)-Longifolene is a naturally occurring.</p>

<p>Theobromine (3,7-Dimethylxanthine), a xanthine alkaloid, is used as a bronchodilator and as a vasodilator.</p>

<p>Applications (S)​-​(-​)​-​1,​2,​4-​Butanetriol is a general reagent used in organic synthesis. Used in the enantioselective preparation of a cyclobutane analogue of Milnacipran.<br>References Nguyen, D. et al.: Org. Chem. Front., 4, 1276 (2017);<br></p>

<p>Ethyl cis-4,7,10,13,16,19-Docosahexaenoate is DHA's ethyl ester, concentrated from tuna oil via alcoholysis.</p>

<p>Tetrasodium glutamate diacetate (Glutamate diacetate tetrasodium) is a degradable chelating agent used as a dietary ingredient.</p>

<p>Leucic acid (α-Hydroxyisocaproic acid) is an amino acid widely found in plants and animals that prevents muscle loss and is broken down into glucose.</p>

<p>Xanthine, a purine breakdown product, is turned into uric acid by xanthine oxidase and blocks adenosine receptors.</p>

<p>D-Glucose-13C6 (Dextrose-13C6), a C13 marker, serves as a metabolic tracer and can be used to study metabolism-related diseases in the body.</p>

<p>Alcohol dehydrogenase is a widely distributed zinc-containing enzyme involved in the detoxification mechanism of environmental alcohols.</p>

<p>4-Vinylphenol, a metabolite from lactic acid bacteria in wine, induces apoptosis. Found in Hedyotis diffusa Willd.</p>

<p>Stability Hygroscopic<br>Applications Retrorsine N-oxide is a pyrrolizidine alkaloid that is naturally found in Senecio isatideus, a flowering plant that is native to the Netherlands. Retrorsine N-oxide is also known to raise blood pressure and can induce abnormal changes in the liver if ingested by animals or humans.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cooper, R.: Trop. Anim. Health Pro., 39, 439 (2007); Mattocks, A.: Xenobiotica, 1, 563 (1971); Neumann, C. &amp; Boland, W.: Helv. Chim. Acta, 73, 754 (1990); Vera, R., et al.: J. Essent. Oil Res., 6, 21 (1994)<br></p>

<p>Estrone-d4 3-Sulfate Sodium Salt is a deuterated compound of Estrone 3-Sulfate Sodium Salt. Estrone 3-Sulfate Sodium Salt has a CAS number of 438-67-5.</p>