Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(6 prodotti)
- BCL(11 prodotti)
- Caspasi(127 prodotti)
- FOXO1(3 prodotti)
- IAP(65 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(126 prodotti)
- PDK(9 prodotti)
- PERK(24 prodotti)
- Chinasi di serina/treonina(15 prodotti)
- Survivin(13 prodotti)
- TNF(91 prodotti)
- c-RET(51 prodotti)
- p53(62 prodotti)
Mostrare 6 più sottocategorie
Trovati 5622 prodotti di "Apoptosi"
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Apolizumab
CAS:<p>Apolizumab (Hu1D10) is a humanized antibody targeting HLA-DR beta-chain; induces apoptosis in CLL cells in vitro.</p>Colore e forma:LiquidMK-0731
CAS:<p>MK-0731 inhibits kinesin spindle protein, disrupting mitosis and triggering apoptosis in KSP-overexpressing tumor cells.</p>Formula:C25H28F3N3O2Colore e forma:SolidPeso molecolare:459.5Kurzipene D
CAS:<p>Kurzipene D: anticancer, induces apoptosis, halts HepG2 at S phase, anti-tumor in zebrafish, inhibits tumor growth and spread.</p>Formula:C26H36O8Colore e forma:SolidPeso molecolare:476.56Sincalide ammonium
CAS:<p>Sincalide ammonium, a CCK analog, stimulates bile release, gallbladder contraction, and sphincter relaxation, aiding in diagnoses.</p>Formula:C49H65N11O16S3Purezza:98.46%Colore e forma:SolidPeso molecolare:1160.3Prolgolimab
CAS:<p>Prolgolimab (BCD-100) is an anti-PD-1 antibody used in melanoma research.</p>Purezza:>95%Colore e forma:LiquidPROTAC Bcl-xL ligand-1
<p>PROTAC Bcl-xL ligand-1 serves as a ligand targeting Bcl-xL, essential in synthesizing PROTACs [1].</p>Formula:C32H29IN4O4S2Colore e forma:SolidPeso molecolare:724.63Akt/NF-κB/MAPK-IN-1
<p>Akt/NF-κB/MAPK-IN-1 (compound 2m) serves as a potent, orally active inhibitor targeting NO with an IC50 of 7.70 μM and demonstrates low toxicity.</p>Formula:C38H56N2O4Purezza:98%Colore e forma:SolidPeso molecolare:604.86Pidilizumab
CAS:<p>Pidilizumab (CT-011), a humanized IgG1κ anti-PD-1 monoclonal antibody, serves as a DLL1 antagonist with potential applications in researching hematologic</p>Purezza:98%Colore e forma:LiquidCamrelizumab
CAS:<p>Camrelizumab (SHR-1210) is a human IgG4-κ monoclonal antibody with high affinity and directed against PD-1.Camrelizumab binds PD-1 with a binding affinity of up</p>Purezza:95% - 98.6%Colore e forma:LiquidPeso molecolare:143.7 kDaMALT1-IN-13
MALT1-IN-13 (compound 10m) is an inhibitor of the mucosa-associated lymphoid tissue lymphoma translocation protein (MALT1), forming a covalent and irreversible bond with the MALT1 protease, thereby inhibiting its activity with an IC50 of 1.7 μM. It suppresses the proliferation of ABC-DLBCL and induces apoptosis in ABC-DLBCL HBL1 cells. Additionally, MALT1-IN-13 regulates the mTOR and PI3K-Akt pathways.Formula:C20H15BrClN3O3S2Peso molecolare:522.94267HDAC6-IN-28
<p>HDAC6-IN-28 (compound 10C) is a potent inhibitor of HDAC6 with an IC50 of 261 nM. It significantly induces apoptosis in B16-F10 cells and causes S phase arrest. Additionally, HDAC6-IN-28 effectively increases the expression of acetylated-α-tubulin both in vitro and in vivo.</p>Formula:C23H16FN3O2Peso molecolare:385.12265Antitumor photosensitizer-3
<p>Antitumor Photosensitizer-3 (Compound I), a chlorin derivative, effectively induces apoptosis and necrosis in tumor cells upon exposure to 650 nm laser</p>Formula:C48H34N4O4Colore e forma:SolidPeso molecolare:730.81ECDD-S16
ECDD-S16 is a potent inhibitor of pyroptosis. It effectively suppresses pyroptosis in Raw264.7 cells activated by surface and endosomal TLR ligands.Formula:C35H31FO12Peso molecolare:662.17995Bursehernin
CAS:<p>Bursehernin is a useful organic compound for research related to life sciences and the catalog number is T124894.</p>Formula:C21H22O6Colore e forma:SolidPeso molecolare:370.401PROTAC GPX4 degrader-2
<p>PROTACGPX4 degrader-2 (compound 18a) is a proteolysis-targeting chimera (PROTAC) that targets the degradation of glutathione peroxidase 4 (GPX4), with a DC50, 48h value of 1.68 μM. It induces the accumulation of lipid peroxides and mitochondrial depolarization, subsequently triggering ferroptosis. Additionally, PROTACGPX4 degrader-2 exhibits antiproliferative activity.</p>Formula:C50H61ClN8O9Peso molecolare:952.425OPBP-1
<p>OPBP-1 is a D-peptide developed through phage display screening, molecular docking, and molecular dynamics simulations. It exhibits high stability, strong antitumor activity, and oral bioavailability. OPBP-1 selectively binds to the PD-L1 protein, significantly blocking the interaction between PD-1 and PD-L1, which helps restore and enhance T lymphocyte function while reducing the proportion of myeloid-derived suppressor cells (MDSCs), counteracting tumor-induced immune evasion. OPBP-1 is applicable for research in cancer immunotherapy.</p>Formula:C64H92N20O19SPeso molecolare:1476.65683Antiproliferative agent-23
<p>Antiproliferative agent-23: destabilizes microtubules, induces apoptosis in cancer cells via mitochondrial path, and triggers ER stress.</p>Formula:C23H28Cl3N3O6PtColore e forma:SolidPeso molecolare:743.93PROTAC GPX4 degrader-4
CAS:<p>PROTACGPX4 degrader-4 is a GPX4 PROTAC degrader with a DC50 of 5.32 nM. It inhibits the activity of cancer cell lines RT4, T24, and J82 with IC50 values of 0.09, 2.97, and 7.58 μM, respectively. This compound elevates lipid ROS levels and induces ferroptosis in T24 and RT4 cells. In T24 tumor-bearing BALB/c nude mouse models, PROTACGPX4 degrader-4 demonstrates antitumor activity. It is applicable to bladder cancer research.</p>Formula:C43H58N2O13Colore e forma:SolidPeso molecolare:810.93Vinepidine sulfate
CAS:Vinepidine (LY-119863) sulfate, a derivative of vincristine, exhibits antitumor activity .Formula:C46H58N4O13SColore e forma:SolidPeso molecolare:907.04IDH1/2-IN-1
<p>IDH1/2-IN-1 (Compound 6b) is a dual inhibitor of IDH1(R132H)/IDH2(R140Q) with IC50 values of 0.22 μM and 1.6 μM, respectively. This compound effectively inhibits tumor growth by suppressing tumor cell proliferation and activating antioxidative enzymes to enhance host defense. Additionally, IDH1/2-IN-1 reduces inflammation and promotes apoptosis, demonstrating significant anti-tumor activity. It is also utilized in leukemia research.</p>Colore e forma:Odour SolidPBE-AMF
PBE-AMF is a prodrug that activates H2O2 and exhibits anticancer activity. It impedes tumor proliferation by inhibiting DNA synthesis, reducing ATP levels, inducing cell death (apoptosis), and blocking the cell cycle. PBE-AMF effectively and selectively inhibits the proliferation of MDA-MB-231 cells (IC50=6.4 μM) while sparing non-cancerous MCF-10A cells.Colore e forma:Odour SolidTNF-α Antagonist
CAS:<p>TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction with</p>Formula:C58H71N11O15S2Colore e forma:SolidPeso molecolare:1226.39YX0798
<p>YX0798 is a selective, orally active CDK9 inhibitor (Kd: 0.28 nM). It downregulates the oncogenic protein c-MYC and the pro-survival protein MCL-1. YX0798 disrupts the cell cycle and causes transcriptome reprogramming, ultimately leading to apoptosis. The compound exhibits antitumor activity.</p>Formula:C21H19ClF3N5O2Colore e forma:SolidPeso molecolare:465.86ASR-488
CAS:<p>ASR-488, an activator of the mRNA-binding protein CPEB1, promotes apoptosis and suppresses the growth of bladder cancer [1].</p>Formula:C33H40O7SColore e forma:SolidPeso molecolare:580.73Zeluvalimab
CAS:<p>Zeluvalimab (AMG-404) is a monoclonal antibody designed to target the PD-1 receptor, and is utilized in cancer research [1].</p>Colore e forma:LiquidFL118
CAS:FL118 is a novel survivin inhibitor that inhibits cancer stem cell-like properties.FL118 is a novel camptothecin analog with anticancer activity that inhibitsFormula:C21H16N2O6Purezza:97.14%Colore e forma:SoildPeso molecolare:392.36Dehydrobruceine B
CAS:<p>Dehydrobruceine B, from Brucea javanica, enhances Cisplatin-induced apoptosis by affecting AIF, Bax, and Keap1-Nrf2.</p>Formula:C23H26O11Colore e forma:SolidPeso molecolare:478.45Reproxalap
CAS:<p>Reproxalap (NS-2) is a dry eye treatment that neutralizes aldehydes like malondialdehyde.</p>Formula:C12H13ClN2OPurezza:99.4% - 99.97%Colore e forma:SolidPeso molecolare:236.7Photosensitizer-6
CAS:<p>Photosensitizer-6 (Compound 4) is a metal ion complex that inhibits TrxR. It induces apoptosis in 4T1 cells, targeting cancer cells and eliminating tumors through chemophototherapy and immunogenic cell death under illumination. Additionally, Photosensitizer-6 can be utilized for tumor imaging.</p>Formula:C47H35AuF6N4P2SColore e forma:SolidPeso molecolare:1060.78Anticancer agent 134
<p>Anticancer Agent 134 (Compound 6a), an environment-sensitive fluorescent probe, induces apoptosis and selectively differentiates between tumor and normal</p>Formula:C34H36ClN7O3S2Purezza:98%Colore e forma:SolidPeso molecolare:690.28NSC90616
<p>NSC90616 is a mutant p53 rescue compound [1] .</p>Formula:C23H30FNa2O9PColore e forma:SolidPeso molecolare:546.43sEH inhibitor-19
<p>sEH inhibitor-19 (Compound (R)-14i) is an orally active soluble epoxide hydrolase (sEH) inhibitor with an IC50 of 1.2 nM. This compound suppresses the expression of TNF-α and IL-6 and exhibits anti-inflammatory effects in mouse models of acute pancreatitis and Carrageenan-induced edema.</p>Formula:C28H28F3N3O4Colore e forma:SolidPeso molecolare:527.535Ac-Trp-Glu-His-Asp-Aldehyde
CAS:<p>Ac-Trp-Glu-His-Asp-Aldehyde is a powerful and selective inhibitor of caspase-1, demonstrating a K_i value of 56 pM [1] [2].</p>Formula:C28H33N7O9Colore e forma:SolidPeso molecolare:611.64-Nitrothalidomide
CAS:<p>4-Nitrothalidomide is a modified form of thalidomide that inhibits the growth and proliferation of HUVEC cells and is commonly used in the synthesis of pomalidomide, which has anticancer potential.</p>Formula:C13H9N3O6Purezza:99.94%Colore e forma:SolidPeso molecolare:303.23Emfizatamab
CAS:<p>Emfizatamab (GNC-038) is a tetravalent antibody that activates CD3 and 4-1BB on T cells while targeting CD19 or PD-L1 on tumor cells, resulting in T-cell-mediated cytotoxicity against human leukemia and lymphoma cells.</p>Colore e forma:LiquidTPP-1 TFA
<p>TPP-1 TFA is a high-affinity PD-L1 inhibitor (KD=95nM) that boosts T-cell function to curb tumor growth.</p>Formula:C109H151F3N34O34S2Colore e forma:SolidPeso molecolare:2602.69EGFR/DHFR-IN-2
<p>EGFR/DHFR-IN-2 (9b) is a dual inhibitor of h-DHFR/EGFR TK, exhibiting IC50 values of 0.192 μM for h-DHFR and 0.109 μM for EGFR. It causes cell cycle arrest at the G1/S phase and induces apoptosis. Additionally, EGFR/DHFR-IN-2 (9b) is a potential inhibitor of CYP2C9 and CYP3A4. This compound can be utilized in cancer research.</p>Formula:C24H16N4O5Colore e forma:SolidPeso molecolare:440.112075-Fluorouracil-13C,15N2
CAS:<p>5-Fluorouracil-13C,15N2 is a standard for quantifying 5-fluorouracil via GC/LC-MS and blocks DNA synthesis, causing cell apoptosis.</p>Formula:C4H3FN2O2Colore e forma:SolidPeso molecolare:133.057Anagrelide hydrochloride monohydrate
CAS:<p>Anagrelide HCl monohydrate is a platelet-reducing imidazoquinazoline for ET and PV research.</p>Formula:C10H10Cl3N3O2Colore e forma:SolidPeso molecolare:310.56Ganglioside GD3 disodium salt
CAS:<p>Ganglioside GD3 disodium salt is a melanoma-associated antigen often targeted in immune therapy for melanomas.</p>Formula:C70H123N3Na2O29Colore e forma:SolidPeso molecolare:1516.71R1-ICR-5
CAS:<p>R1-ICR-5 is a selective PROTAC degrader targeting serine/threonine-protein kinase 1 (RIPK1). Mediated by VHL, R1-ICR-5 promotes the degradation of RIPK1, disrupting the TNFR1 and TLR3/4 signaling hubs, enhancing NF-κB, MAPK, and IFN signal output, and facilitating RIPK3 activation and necroptosis induction. R1-ICR-5 holds potential for research in cancer and inflammatory diseases.</p>Formula:C54H70N8O7S2Colore e forma:SolidPeso molecolare:1007.31Necroptosis-IN-4
<p>Necroptosis-IN-4 is an effective inhibitor of necroptosis, specifically targeting RIP kinase 1 (RIPK1) without inhibitory activity against RIPK3. It exhibits weak inhibitory effects on VEGFR1/2 and PDGFR-α.</p>Colore e forma:Odour SolidHSP70-IN-6
<p>HSP70-IN-6 (Compound JL-15) acts as an inhibitor of the Hsp70-Bim protein-protein interactions (PPI) with an IC50 value of 70 nM. It induces apoptosis in chronic myeloid leukemia (CML) cells with EC50 values of 0.43 μM (BV173), 0.88 μM (K562), and 0.19 μM (K562-R3).</p>Colore e forma:Odour SolidCYP51/PD-L1-IN-3
<p>CYP51/PD-L1-IN-3 (compound L21), a quinazoline with antifungal properties, serves as a dual inhibitor targeting CYP51 (IC50: 0.205 μM) and PD-L1 (IC50: 0.039 μM</p>Formula:C27H28N6O2Colore e forma:SolidPeso molecolare:468.55Antitumor agent-64
CAS:<p>Antitumor Agent-64 (Compound 8d), a diosgenin derivative, exhibits potent cytotoxic activity against the A549 cell line and induces apoptosis in A549 cells</p>Formula:C35H47N3O3SColore e forma:SolidPeso molecolare:589.83Mcl-1 inhibitor 15
<p>Mcl-1 Inhibitor 15 (Compound (Ra)-15), with a K i of 0.02 nM, is utilized in cancer research [1].</p>Formula:C40H42ClFN6O4SColore e forma:SolidPeso molecolare:757.32Odoroside A
CAS:Odoroside A, from Nerium oleander leaves, induces cancer cell death via ROS/p53, causing apoptosis and cell cycle arrest.Formula:C30H46O7Colore e forma:SolidPeso molecolare:518.68Beclin1-Bcl-2 interaction inhibitor 1
<p>Beclin1-Bcl-2 Interaction Inhibitor 1 effectively disrupts the binding of Beclin 1 to Bcl-2, and is utilized in cancer and neurodegeneration research [1].</p>Colore e forma:Odour SolidTripchlorolide
<p>Tripchlorolide is a useful organic compound for research related to life sciences and the catalog number is T126047.</p>Formula:C20H25ClO6Colore e forma:SolidPeso molecolare:396.86Diprovocim-1
CAS:<p>Diprovocim-1: TLR1/2 agonist; triggers TNF-α in THP-1 cells; boosts ovalbumin IgG1 & CTLs against tumors with anti-PD-L1 in mice.</p>Formula:C56H56N6O6Colore e forma:SolidPeso molecolare:909.1Cytostatin
CAS:<p>Cytostatin: Natural antitumor, inhibits cell adhesion, blocks B16 melanoma, induces apoptosis, selectively targets PP2A (IC50 = 29 nM).</p>Formula:C21H33O7PColore e forma:SolidPeso molecolare:428.462hCAIX-IN-13
CAS:<p>hCAIX-IN-13 (Pt2) inhibits CAIX with 6.57 μM IC50, curbs cancer cell growth, and induces apoptosis for cancer research.</p>Formula:C37H33F3N6O7PtS2Colore e forma:SolidPeso molecolare:989.9Angiogenesis inhibitor 3
CAS:<p>Angiogenesis Inhibitor 3 (compound 8) is a potent anti-cancer agent, blocking HUVEC/HCT-15 cell growth and inducing apoptosis.</p>Formula:C44H42BrN3O9Colore e forma:SolidPeso molecolare:836.72Lactoferrin (17-41)
CAS:<p>Amino acids 17-41 of lactoferrin, lactoferricin B, enhance anti-fungal effects, targeting Candida Albicans.</p>Formula:C141H224N46O29S3Purezza:98%Colore e forma:SolidPeso molecolare:3123.77cis-Clovamide
CAS:<p>cis-Clovamide is a naturally occurring phenolic compound with noteworthy antioxidant, anti-inflammatory, and antiapoptotic properties.</p>Formula:C18H17NO7Colore e forma:SolidPeso molecolare:359.334MS41
CAS:<p>MS41 is a selective eleven-nineteen leukemia (ENL) PROTAC degrader, with DC50s values of 3.50 nM (MV4;11), 2.84 nM (SEMK2), 3.03 nM (Jurkat), and 26.58 nM (KASUMI1). This compound effectively inhibits the growth of ENL-dependent leukemia cells, induces G1 cell cycle arrest, and increases cellular apoptosis (Apoptosis). Additionally, MS41 reduces chromatin occupancy related to ENL-mediated transcription elongation mechanisms and suppresses the expression of oncogenes and the progression of leukemia.</p>Formula:C56H70N8O9SColore e forma:SolidPeso molecolare:1031.27CDK9-IN-24
<p>CDK9-IN-24 (compound 21a) is a potent and selective inhibitor of CDK9 that exhibits a pronounced inhibitory impact on tumor proliferation.</p>Formula:C27H31N3O4Purezza:98%Colore e forma:SolidPeso molecolare:461.55Met-12
CAS:Met-12 is a peptide inhibitor of the Fas receptor. It suppresses Fas receptor-mediated apoptosis in photoreceptor cells and reduces Caspase activation, making it a potential candidate for research on photoreceptor protectants.Formula:C71H99N17O17Colore e forma:SolidPeso molecolare:1462.65D-CopA3
CAS:<p>D-CopA3 is an inhibitor of MDM2 and an activator of the p53 signaling pathway. It exhibits cytotoxicity in colorectal cancer cells HCT-116, LoVo, and RKO with IC50 values of 15-18 μM and induces JNK/Beclin-1 mediated autophagy. D-CopA3 downregulates the expression of the cell cycle inhibitor protein p21Cip1/Waf1, enhances mucosal barrier function, and reduces infiltration of inflammatory mediators. It shows anti-inflammatory properties in mouse models of acute enteritis induced by C. difficile toxin A and chronic colitis induced by DSS. Additionally, D-CopA3 demonstrates antitumor activity in a mouse HCT-116 xenograft model.</p>Formula:C96H184N30O18S2Colore e forma:SolidPeso molecolare:2110.81TAT-NEP1-40 acetate
<p>TAT-NEP1-40 acetate, a potential therapeutic for axonal regeneration and functional recovery post-stroke, safeguards PC12 cells from oxygen and glucose</p>Formula:C268H438N88O77·xC2H4O2Purezza:98%Colore e forma:SolidPeso molecolare:6124.89 (free base)CAY10726
CAS:<p>CAY10726, an arylurea fatty acid, cuts ATP by 28% and promotes apoptosis in breast cancer cells by depleting mitochondrial lipids.</p>Formula:C24H36ClF3N2O3Colore e forma:SolidPeso molecolare:493Pipernonaline
CAS:<p>Pipernonaline is a useful organic compound for research related to life sciences. The catalog number is T124000 and the CAS number is 88660-10-0.</p>Formula:C21H27NO3Colore e forma:SolidPeso molecolare:341.451eIF4E-IN-2
CAS:<p>eIF4E-IN-2 effectively inhibits eIF4e, crucial for research on diseases like cancer.</p>Formula:C37H33ClF2N8O4S2Colore e forma:SolidPeso molecolare:791.29DB2115 tertahydrochloride
CAS:<p>DB2115 (tertahydrochloride) inhibits PU.1, key in leukemia; potential for cancer research.</p>Formula:C32H34Cl4N8O2Colore e forma:SolidPeso molecolare:704.48FD2157
<p>FD2157, a photosensitive PI3K inhibitor, exhibits inhibitory IC50 values of 43 nM for PI3Kα, 83 nM for PI3Kβ, 84 nM for PI3Kγ, and 14 nM for PI3Kδ.</p>Formula:C27H21ClN6O8SPurezza:98%Colore e forma:SolidPeso molecolare:625.01Anticancer agent 106
<p>Compound 106 (compound 10ic) induces apoptosis in B16-F10 melanoma cells and potently inhibits metastatic nodules in mouse models of lung metastatic melanoma,</p>Formula:C26H25N3O4SPurezza:98%Colore e forma:SolidPeso molecolare:475.56Antiproliferative agent-27
<p>Antiproliferative Agent-27 (Compound 11) is a notable antiproliferative agent that markedly diminishes tumor cell colony formation and induces apoptosis,</p>Formula:C26H40FNO6SPurezza:98%Colore e forma:SolidPeso molecolare:513.66Ferroptosis-IN-1
<p>Ferroptosis-IN-1, a diterpene derived from A.</p>Formula:C22H34O5Purezza:98%Colore e forma:SolidPeso molecolare:378.5EGFR-IN-78
<p>EGFR-IN-78 (compound A5), a 2-aminopyrimidine derivative, serves as a reversible EGFR C797S-TK inhibitor and an apoptosis inducer.</p>Formula:C23H32BrN7O2SPurezza:98%Colore e forma:SolidPeso molecolare:550.51GPX4-IN-7
<p>GPX4-IN-7 (Compound 31), an indirubin derivative, serves as a ferroptosis inducer in colon cancer treatment.</p>Formula:C25H23ClN4O4Purezza:98%Colore e forma:SolidPeso molecolare:478.93Anti-Mouse PD-1 (LALA-PG) Antibody (RMP1-14)
<p>Anti-MousePD-1(LALA-PG) Antibody (RMP1-14) is an IgG2a, κ antibody inhibitor derived from mice that targets and inhibits mouse PD-1.</p>Colore e forma:Odour LiquidTQB-2858
<p>TQB-2858 is a bifunctional fusion protein composed of an anti-PD-L1 monoclonal antibody fused with the extracellular domain of the TGF-β receptor. It exhibits high affinity for PD-L1, TGF-β1, and TGF-β3, and demonstrates a high target occupancy rate for PD-L1. TQB-2858 can be used in research on osteosarcoma and alveolar soft part sarcoma (ASPS).</p>Colore e forma:Odour Liquidfac-[Re(CO)3(L6)(H2O)][NO3]
<p>Compound 6, fac-[Re(CO)3(L6)(H2O)][NO3], a rhenium(I) tricarbonyl aqua complex, serves as an anticancer agent by disrupting mitochondrial function.</p>Formula:C24H14N5O7ReSPurezza:98%Colore e forma:SolidPeso molecolare:702.67Anticancer agent 133
<p>Compound Rh2 (Anticancer agent 133) is a cytotoxic and antimetastatic agent that induces cell cycle arrest, apoptosis, and autophagy.</p>Formula:C24H19Cl3N5ORhPurezza:98%Colore e forma:SolidPeso molecolare:602.71Antimycin A2c
<p>Anticancer Agent 141 (Compound AE), an antimycin alkaloid, exhibits inhibitory potential against HPV-infected cervical cancer.</p>Formula:C28H40N2O9Purezza:98%Colore e forma:SolidPeso molecolare:548.63RET-IN-26
<p>RET-IN-26 (compound D5) is a kinase inhibitor that selectively targets the RET protein with an IC50 value of 0.33 μM [1].</p>Colore e forma:Odour SolidAnti-inflammatory agent 45
<p>Compound 2v (Anti-inflammatory agent 45) demonstrates anticancer properties with direct inhibitory impacts on the proliferation of various blood malignancies,</p>Formula:C25H22BrNO6Purezza:98%Colore e forma:SolidPeso molecolare:512.35BAY 1892005
CAS:<p>BAY 1892005 is a p53 protein modulator that targets the p53 condenser for the study of diseases associated with misfolded p53 protein</p>Formula:C11H8ClFN2OSPurezza:99.62%Colore e forma:SoildPeso molecolare:270.71Ferroptosis-IN-13
<p>Ferroptosis-IN-13 (compound NY-26) is an inhibitor of ferroptosis. It effectively suppresses RSL3-induced ferroptosis in 786-O cells, with an EC50 value of 62 nM.</p>Formula:C32H30F2N4O3Colore e forma:SolidPeso molecolare:556.602BK60106
<p>BK60106 is a selective and direct inhibitor of the transmembrane protein CD99, which causes cell death in Ewing Sarcoma cells.</p>Formula:C15H15FN6O3Purezza:99.30% - >99.99%Colore e forma:SolidPeso molecolare:346.321,8-Cineole
CAS:<p>Eucalyptol, a natural monoterpenoid and cyclic ether found in eucalyptus species, effectively controls excessive airway mucus secretion and asthma by inhibiting pro-inflammatory cytokines. It serves as an efficacious treatment for non-purulent sinusitis, reducing inflammation and pain when applied topically, and demonstrating leukemic cell-killing capabilities in vitro.</p>Formula:C10H18OPurezza:97.44% - 97.44%Colore e forma:SolidPeso molecolare:154.25p53-Mdm2 inhibitor 4
CAS:<p>p53-Mdm2 inhibitor 4 inhibits the p53-MDM2 protein-protein interaction.</p>Formula:C23H20FN3O3Purezza:98.66%Colore e forma:SoildPeso molecolare:405.42Kusunokinin
<p>Kusunokinin is a useful organic compound for research related to life sciences and the catalog number is T124612.</p>Formula:C21H22O6Colore e forma:SolidPeso molecolare:370.401(E/Z)-Squalene
CAS:<p>(E/Z)-Squalene modulates ROS, triggers apoptosis/necrosis, reduces liver cholesterol and triglycerides.</p>Formula:C30H50Purezza:99.28%Colore e forma:SolidPeso molecolare:410.72CST626
CAS:<p>CST626 is a PROTAC degrader that targets XIAP, cIAP1, and cIAP2.</p>Formula:C61H82N8O9SPurezza:95.87%Colore e forma:SolidPeso molecolare:1103.42Δ8-Tetrahydrocannabinoquinone
CAS:<p>Δ8-Tetrahydrocannabinoquinone (HU-336) is a potent anti-angiogenic agent that inhibits angiogenesis by directly inducing apoptosis in vascular endothelial cells. It achieves this without altering the expression of pro-angiogenic and anti-angiogenic cytokines and receptors. Δ8-Tetrahydrocannabinoquinone also shows significant effectiveness against tumor xenografts in nude mice.</p>Formula:C21H28O3Colore e forma:SolidPeso molecolare:328.45AKT-IN-18
<p>AKT-IN-18, an Akt inhibitor, demonstrates an IC50 value of 69.45 μM in A549 cells, effectively impeding Akt activity.</p>Formula:C19H14ClN5O2SPurezza:98%Colore e forma:SolidPeso molecolare:411.86BM-962
CAS:<p>BM-962 (Compound 31) is a potent small-molecule inhibitor with an IC50 value of 4 nM (Ki=0.8 nM) for Bcl-2 and an IC50 of 3.9 nM (Ki<1 nM) for Bcl-xL. It inhibits H1417 and H146 cell lines with IC50 values of 9 and 13 nM, respectively, and shows potential for use in cancer research.</p>Formula:C53H58ClF3N6O7S3Colore e forma:SolidPeso molecolare:1079.71AZD5582 TFA
<p>AZD5582 TFA is a potent IAP antagonist that binds to the BIR3 domain of cIAP1, cIAP2, and XIAP with IC50 values of 15, 21, and 15 nM, respectively.AZD5582 TFA</p>Formula:C60H79F3N8O10Purezza:99.89%Colore e forma:SoildPeso molecolare:1129.31Diphenhydramine hydrochloride
CAS:<p>DPH: antihistamine for cough, nausea, itching, allergy, Parkinson's, sleep aid, cold remedy.</p>Formula:C17H22ClNOPurezza:99.84%Colore e forma:Taste Ph (5% Aqueous Solution) 4-6 (Ntp 1992)Peso molecolare:291.82MYC-RIBOTAC
<p>MYC-RIBOTAC, a ribonuclease-targeting chimera (RIBOTAC) specific to the MYC internal ribosome entry site (IRES), comprises an MYC mRNA-binding element tethered</p>Formula:C55H58N10O11SPurezza:98%Colore e forma:SolidPeso molecolare:1067.17TAPI 0
CAS:<p>ADAM-17 (TACE) and MMP inhibitor; attenuates TNF-α processing. Acts in concert with GM6001 to inhibit Chlamydia trachomatis growth.</p>Formula:C24H32N4O5Purezza:98%Colore e forma:SolidPeso molecolare:456.5484-B10
CAS:<p>84-B10 provides protection in cisplatin-induced acute kidney injury, reversing lipid peroxidation accumulation and downregulation of key ferroptosis inhibitors.</p>Formula:C25H22F3NO5Purezza:99.76%Colore e forma:SolidPeso molecolare:473.44Ac-Pro-Gly-Pro-OH
CAS:<p>Ac-Pro-Gly-Pro-OH can be used as a CXCR2 agonist with bactericidal and anti-inflammatory activity for the study of sepsis and lung inflammation.</p>Formula:C14H21N3O5Purezza:98.32%Colore e forma:SolidPeso molecolare:311.33Z-VDVA-(DL-Asp)-FMK
CAS:<p>Z-VDVA-(DL-Asp)-FMK is a derivative compound of Z-VDVAD-FMK specifically designed as an inhibitor targeting caspase-2.</p>Formula:C32H46FN5O11Colore e forma:SolidPeso molecolare:695.742Thalidomide-O-amido-C6-NH2
CAS:<p>Thalidomide-O-amido-C6-NH2 is a synthetic E3 ligase used for PROTAC creation, containing cereblon ligand and linker.</p>Formula:C21H26N4O6Colore e forma:SolidPeso molecolare:430.45Tilogotamab
CAS:<p>Tilogotamab (GEN-1029) is an agonistic hexameric complex targeting two independent epitopes on DR5, used for studying multiple myeloma (MM).</p>Purezza:95%Colore e forma:LiquidBorrelidin
CAS:<p>Borrelidin (Treponemycin) is an inhibitor of trehalose-6-phosphate synthase, a nitrogen-containing macrolide antibiotic isolated from Streptomyces rochei.</p>Formula:C28H43NO6Purezza:98%Colore e forma:White To Off-White PowderPeso molecolare:489.64PROTAC Bcl-xL degrader-3
CAS:<p>PROTAC Bcl-xL degrader-3 is a potent ROTAC Bcl-xL degrader.</p>Formula:C82H105ClF3N11O11S4Colore e forma:SolidPeso molecolare:1641.49MD-222
CAS:MD-222: a first-in-class, highly potent PROTAC that degrades MDM2, activates p53, and exhibits anticancer properties.Formula:C48H47Cl2FN6O6Colore e forma:SolidPeso molecolare:893.84
