CymitQuimica logo
Apoptosi

Apoptosi

Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.

Sottocategorie di "Apoptosi"

Mostrare 6 più sottocategorie

Trovati 6231 prodotti di "Apoptosi"

Ordinare per

Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
prodotti per pagina.
  • CV-4-26


    CV-4-26 (Compound 22) acts as a covalent inhibitor of TEAD. By inhibiting YAP/TEAD-driven transcription, it diminishes the expression of CTGF and CYR61. Furthermore, CV-4-26 impedes colony formation in Huh7 and HepG2 cells, inducing cell cycle arrest and apoptosis (apoptosis). This compound demonstrates anti-tumoral activity against hepatocellular carcinoma (HCC) and hepatoblastoma (HB).
    Colore e forma:Odour Solid

    Ref: TM-T200708

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Shepherdin (79-87)

    CAS:
    Shepherdin 79-87: Amino acid fragment 79-87 of Hsp90/Survivin antagonist with anticancer properties.
    Formula:C41H64N12O12S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:949.09

    Ref: TM-T12896

    25mg
    1.369,00€
  • Varlilumab

    CAS:
    Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and can be used to study advanced solid tumors.
    Purezza:SDS-PAGE:95% SEC-HPLC:98.65%
    Colore e forma:Liquid
    Peso molecolare:146 kDa

    Ref: TM-T76706

    1mg
    200,00€
    5mg
    485,00€
    10mg
    802,00€
    25mg
    1.215,00€
    50mg
    1.639,00€
  • ILS-920

    CAS:
    ILS-920, a Rapamycin analog, has reduced immunosuppression, enhanced neuroprotection, and preferentially binds FKBP52 and L-type VGCC β1.
    Formula:C57H86N2O14
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1023.3

    Ref: TM-T13734

    25mg
    1.369,00€
  • Anticancer agent 157


    Anticancer Agent 157 (compound 15) is a nitric oxide (NO) inhibitor with IC50 values of 0.62 μg/mL, exhibiting both anti-inflammatory and anticancer effects.
    Formula:C14H20O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:220.31

    Ref: TM-T78855

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Albanol B

    CAS:
    Albanol B, from mulberries, combats Alzheimer's, bacteria, and oxidation, hinders cancer growth, and triggers cell arrest and apoptosis.
    Formula:C34H22O8
    Colore e forma:Solid
    Peso molecolare:558.53

    Ref: TM-T75602

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • YN14-H


    YN14-H is a PROTAC degrader that targets KRASG12C. It effectively inhibits the growth of NCI-H358 and MIA PaCa-2 cells, with IC50 values of 0.042 μM and 0.021 μM, respectively, and DC50 values of 28.9 nM and 18.1 nM. YN14-H significantly induces apoptosis and suppresses cell migration. It demonstrates favorable pharmacokinetics and excellent in vivo antitumor activity.
    Colore e forma:Odour Solid

    Ref: TM-T206431

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • RTX-002


    RTX-002 is a human monoclonal antibody (mAb) targeting PDCD1/PD-1/CD279. This compound is applicable in the research of autoimmune diseases such as systemic lupus erythematosus and multiple sclerosis.
    Colore e forma:Odour Liquid

    Ref: TM-T9901A-1582

    1mg
    Prezzo su richiesta
    5mg
    Prezzo su richiesta
  • PL120131


    PL120131 is a PD-1/PD-L1 inhibitory peptide that disrupts the interaction between PD-1 and PD-L1 by binding to PD-1. This compound can inhibit the apoptosis signaling pathway mediated by PD-1, thereby preventing apoptosis (apoptosis) in Jurkat cells and primary lymphocytes. Additionally, PL120131 supports cytotoxic T lymphocytes (CTL) in exhibiting antitumor activity.
    Formula:C62H105N19O18
    Colore e forma:Solid
    Peso molecolare:1404.61

    Ref: TM-TP3086

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Apoptosis Compound Library


    A unique collection of 1760 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;
    Colore e forma:Odour Solid

    Ref: TM-L9000

    1mg
    Prezzo su richiesta
    30μL*10mM (DMSO)
    Prezzo su richiesta
    50μL*10mM (DMSO)
    Prezzo su richiesta
    100μL*10mM (DMSO)
    Prezzo su richiesta
    250μL*10mM (DMSO)
    Prezzo su richiesta
  • Bleomycin A5

    CAS:
    Bleomycin A5, or Pingyangmycin, is an oral glycopeptide antibiotic and acts as an antineoplastic and apoptosis inducer.
    Formula:C57H89N19O21S2
    Colore e forma:Solid
    Peso molecolare:1440.56

    Ref: TM-T75508

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Pomalidomide-C5-Dovitinib

    CAS:
    Pomalidomide-C5-Dovitinib (compound 2) is a PROTAC that links Pomalidomide and Dovitinib via a CRBN connector, exhibiting potent antiproliferative activity in
    Formula:C39H38FN9O6
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:747.77

    Ref: TM-T81421

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Tubulin polymerization-IN-45


    Tubulin polymerization-IN-45, a tubulin-targeting agent, acts as a tubulin polymerization inhibitor by binding to the tubulin's colchicine site.
    Formula:C20H18N4O3
    Colore e forma:Solid
    Peso molecolare:362.38

    Ref: TM-T79341

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • TNF-α (31-45), human

    CAS:
    TNF-α (31-45), human is a peptide of tumor necrosis factor-α.
    Formula:C69H122N26O22
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1667.895

    Ref: TM-T19584

    100mg
    Prezzo su richiesta
    500mg
    Prezzo su richiesta
  • CS4


    CS4 is a selective HDAC inhibitor, with IC50 values for HDAC1, HDAC6, HDAC8, HDAC4, and HDAC11 reported as 38 nM, 12 nM, 5.8 μM, 19 μM, and 61 μM, respectively. It enhances the acetylation of α-tubulin and histone 3 (histone 3). Additionally, CS4 activates PPARγ and blocks glycolysis (glycolysis). It induces cell cycle arrest at the G2 phase and triggers apoptosis (apoptosis), exhibiting anticancer effects both in vitro and in vivo.
    Colore e forma:Odour Solid

    Ref: TM-T206840

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Nrf2 activator-9


    Nrf2 activator-9 (compound D-36) is an agent that mitigates oxidative stress by inhibiting the apoptosis of HUVEC cells induced by oxidized low-density
    Formula:C26H27N5O4
    Colore e forma:Solid
    Peso molecolare:473.52

    Ref: TM-T79702

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Endoplasmic Reticulum Stress Compound Library


    A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS);
    Colore e forma:Odour Solid

    Ref: TM-L9700

    1mg
    Prezzo su richiesta
    30μL*10mM (DMSO)
    Prezzo su richiesta
    50μL*10mM (DMSO)
    Prezzo su richiesta
    100μL*10mM (DMSO)
    Prezzo su richiesta
    250μL*10mM (DMSO)
    Prezzo su richiesta
  • PROTAC KDM4 degrader-1


    PROTACKDM4 degrader-1 (Compound 11) is a proteolysis-targeting chimera (PROTAC) degrader specifically designed for KDM4. It effectively degrades KDM4A-C while sparing KDM4D. In esophageal cancer cells, PROTACKDM4 degrader-1 demonstrates strong antiproliferative activity, inducing apoptosis and cell cycle arrest, and inhibits lysine demethylation of histone H3.
    Colore e forma:Odour Solid

    Ref: TM-T206971

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • 1,2,3,4-Tetrahydronaphthalen-2-ol

    CAS:
    1,2,3,4-Tetrahydronaphthalen-2-ol exhibits weak inhibitory activity against Bcl-xL and is widely used in biochemical experiments and drug synthesis research.
    Formula:C10H12O
    Colore e forma:Solid
    Peso molecolare:148.2

    Ref: TM-TN9646

    1mg
    96,00€
    5mg
    178,00€
    10mg
    276,00€
    25mg
    469,00€
  • PH14


    PH14, a dual PI3K/HDAC inhibitor, demonstrates potent inhibition with IC50 values of 20.3 nM for PI3Kα and 24.5 nM for HDAC3.
    Purezza:98%
    Colore e forma:Odour Solid

    Ref: TM-T81499

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • KC01

    CAS:
    KC01 selectively inhibits ABHD16A (IC50: 0.2-0.5 μM), much more potent than KC02 (>10 μM); human ABHD16A IC50: 90±20 nM.
    Formula:C22H39NO3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:365.558

    Ref: TM-T22888

    500µg
    358,00€
    1mg
    627,00€
  • Avotaciclib hydrochloride


    Avotaciclib hydrochloride, a CDK1 inhibitor, is the hydrochloride salt of Avotaciclib and exhibits potential therapeutic use in specific malignancies, including
    Formula:C13H12ClN7O
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:317.73

    Ref: TM-T78137

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Thalidomide-NH-C6-NH2 TFA

    CAS:
    Thalidomide-based cereblon ligand linked to PROTAC technology as E3 ligase ligand-linker.
    Formula:C21H25F3N4O6
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:486.44

    Ref: TM-T18809

    2mg
    63,00€
    5mg
    92,00€
  • P1D-34


    P1D-34 is a Pin1 PROTAC degrader with a DC50 value of 177 nM. It downregulates Pin1 substrate proteins, including Cyclin D1, Rb, Mcl-1, Akt, and c-Myc. Additionally, P1D-34 exhibits antiproliferative activity across various acute myeloid leukemia (AML) cell lines and induces DNA damage and apoptosis by generating reactive oxygen species (ROS).
    Colore e forma:Odour Solid

    Ref: TM-T206664

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • S65487 hydrochloride

    CAS:
    S65487 (VOB560) hydrochloride, a potent and selective Bcl-2 inhibitor, is effective against BCL-2 mutations, including G101V and D103Y.
    Formula:C41H42Cl2N6O4
    Colore e forma:Solid
    Peso molecolare:753.73

    Ref: TM-T39135

    10mg
    627,00€
    25mg
    1.341,00€
  • Anti-inflammatory agent 61


    Compound 5b (Anti-inflammatory agent 61) is a potent anti-inflammatory agent that diminishes TNF-α expression in LPS-induced inflammation within RAW 264.7 cells
    Colore e forma:Odour Solid

    Ref: TM-T83051

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Bim BH3

    CAS:
    Bim BH3 is a bioactive peptide that belongs to the pro-apoptotic Bcl-2 family of proteins.
    Formula:C108H170N32O31S
    Colore e forma:Solid
    Peso molecolare:2444.77

    Ref: TM-T80038

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • FHD-286

    CAS:
    FHD-286 is an inhibitor of BRM/BRG1 ATPase and can be used for studies on the treatment of BAF-related disorders such as acute myeloid leukemia.
    Formula:C24H30N6O6S2
    Purezza:99.73%
    Colore e forma:Solid
    Peso molecolare:562.66

    Ref: TM-T9749

    1mg
    144,00€
    5mg
    283,00€
    1mL*10mM (DMSO)
    359,00€
    10mg
    454,00€
    25mg
    615,00€
    50mg
    777,00€
    100mg
    1.064,00€
  • PRMT5-IN-31


    PRMT5-IN-31 (Compound 3m), a selective PRMT5 inhibitor (IC50: 0.31 μM), increases hnRNP E1 protein levels by occupying the substrate site of PRMT5 and
    Formula:C21H24N2O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:336.43

    Ref: TM-T79274

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • RMC-9805

    CAS:
    RMC-9805(Zoldonrasib) is a KRAS G12D inhibitor with anti-tumor and anti-proliferative activity for the study of pancreatic cancer.
    Formula:C63H88F3N11O7
    Purezza:98.10% - 99.99%
    Colore e forma:Solid
    Peso molecolare:1168.44

    Ref: TM-T78212

    1mg
    120,00€
    5mg
    295,00€
    10mg
    460,00€
    1mL*10mM (DMSO)
    650,00€
    25mg
    753,00€
    50mg
    1.099,00€
    100mg
    1.620,00€
  • MS105

    CAS:
    MS105 is an orally active, selective protein tyrosine kinase 6 (PTK6) PROTAC degrader. It recruits the VHL E3 ligase through a VHL ligand fragment, facilitating ubiquitination and proteasomal degradation of PTK6, thereby inhibiting the proliferation and migration of breast cancer cells and inducing apoptosis (apoptosis). MS105 is a promising compound for breast cancer research.
    Formula:C56H70FN13O6S
    Colore e forma:Solid
    Peso molecolare:1072.30

    Ref: TM-T207347

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • FR900359

    CAS:
    FR900359 is a macrocyclic Gq protein inhibitor that inhibits melanoma cell proliferation and can be used to study asthma, inflammation and cancer.
    Formula:C49H75N7O15
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1002.16

    Ref: TM-T27387

    1mg
    1.198,00€
  • Pimagedine

    CAS:
    Pimagedine is a prototype therapeutic agent for the prevention of formation of advanced glycation endproducts.
    Formula:CH6N4
    Colore e forma:Solid
    Peso molecolare:74.09

    Ref: TM-T34066

    25mg
    1.369,00€
  • Z-VEID-FMK

    CAS:
    Z-VEID-FMK is a selective caspase-6 peptide inhibitor that irreversibly covalently binds to the enzyme, thereby inhibiting apoptosis and DNA breakage.
    Formula:C31H45FN4O10
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:652.71

    Ref: TM-T23555

    1mg
    99,00€
    5mg
    254,00€
    10mg
    421,00€
    25mg
    672,00€
  • Sterigmatocystine

    CAS:
    Sterigmatocystine, a G1 phase and DNA synthesis inhibitor, curbs p21 and is a mycotoxin precursor from Aspergillus versicolor.
    Formula:C18H12O6
    Purezza:98%
    Colore e forma:Pale-Yellow Crystals Pale Yellow Solid
    Peso molecolare:324.28

    Ref: TM-T16942

    10mg
    Prezzo su richiesta
    1mg
    328,00€
  • Disitertide

    CAS:
    Disitertide (P144) is an inhibitor of TGF-β1.
    Formula:C68H109N17O22S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1580.84

    Ref: TM-T11052

    1mg
    577,00€
  • Thalidomide-5-propoxyethanamine

    CAS:
    Thalidomide-5-propoxyethanamine acts as a cereblon (CRBN) ligand derived from Thalidomide, and it serves the purpose of recruiting the CRBN protein.
    Formula:C18H21N3O5
    Colore e forma:Solid
    Peso molecolare:359.38

    Ref: TM-T39892

    25mg
    1.369,00€
  • YL5084

    CAS:
    YL5084 is a selective JNK2/3 inhibitor with IC50s: JNK2 (70 nM), JNK3 (84 nM), and antiproliferative, apoptosis-inducing effects.
    Formula:C35H36N8O2
    Colore e forma:Solid
    Peso molecolare:600.71

    Ref: TM-T74850

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • PROTAC GPX4 degrader-4

    CAS:
    PROTACGPX4 degrader-4 is a GPX4 PROTAC degrader with a DC50 of 5.32 nM. It inhibits the activity of cancer cell lines RT4, T24, and J82 with IC50 values of 0.09, 2.97, and 7.58 μM, respectively. This compound elevates lipid ROS levels and induces ferroptosis in T24 and RT4 cells. In T24 tumor-bearing BALB/c nude mouse models, PROTACGPX4 degrader-4 demonstrates antitumor activity. It is applicable to bladder cancer research.
    Formula:C43H58N2O13
    Colore e forma:Solid
    Peso molecolare:810.93

    Ref: TM-T207431

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • (±)-Enterodiol

    CAS:
    "(±)-Enterodiol, the racemate of Enterodiol, is metabolized from lignans found in whole-grain cereals, nuts, legumes, flaxseed, and vegetables by human intestinal bacteria. This compound exhibits apoptotic effects in colorectal cancer (CRC) cells and has been identified to possess anti-cancer activities [1] [2]."
    Formula:C18H22O4
    Colore e forma:Solid
    Peso molecolare:302.36

    Ref: TM-TN7345

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • RMC-6291

    CAS:
    RMC-6291: Oral, covalent KRAS G12C inhibitor, blocks signaling, forms tri-complex with CypA, suppresses RAS activity in tumors.
    Formula:C55H78FN9O8
    Purezza:98.73% - 99.92%
    Colore e forma:Solid
    Peso molecolare:1012.26

    Ref: TM-T75131

    1mg
    150,00€
    5mg
    289,00€
    10mg
    522,00€
    1mL*10mM (DMSO)
    580,00€
    25mg
    1.063,00€
    50mg
    1.755,00€
  • CPTH2 (hydrochloride) (357649-93-5 free base)

    CAS:
    CPTH2 is an inhibitor of the HAT activity of Gcn5.
    Formula:C14H15Cl2N3S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:328.26

    Ref: TM-T22693

    5mg
    316,00€
    10mg
    416,00€
  • PROTAC Bcl-xL degrader-2


    PROTAC Bcl-xL degrader-2, based on von Hippel-Lindau ligand, is a potent degrader of Bcl-xL (a Bcl-2 family member), demonstrating an IC 50 of 0.6 nM.
    Formula:C68H80N8O14S3
    Colore e forma:Solid
    Peso molecolare:1329.6

    Ref: TM-T74138

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • NEP162

    CAS:
    NEP162 is a BRD4 PROTAC degrader with DC50 values of 1.2 μM in SW480 cells and 1.6 μM in U2OS cells. NEP162 exhibits antiproliferative activity, effectively inhibiting tumor growth and inducing apoptosis. It is applicable in research on cancers such as osteosarcoma, colorectal cancer, and non-small cell lung cancer.
    Formula:C50H56ClN11O3S
    Colore e forma:Solid
    Peso molecolare:926.57

    Ref: TM-T211584

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Monactin

    CAS:
    Monactin is a Marcrotetrolide antibiotic produced by cycloheximide producing species of Streptomyces. It is a homolog of nonactin from the same species.
    Formula:C41H66O12
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:750.96

    Ref: TM-T25827

    1mg
    610,00€
    5mg
    2.277,00€
  • Akt/NF-κB/MAPK-IN-1


    Akt/NF-κB/MAPK-IN-1 (compound 2m) serves as a potent, orally active inhibitor targeting NO with an IC50 of 7.70 μM and demonstrates low toxicity.
    Formula:C38H56N2O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:604.86

    Ref: TM-T78838

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • HDAC6-IN-22


    HDAC6-IN-22 (compound 30), an HDAC6 inhibitor, exhibits an IC50 of 4.63 nM and demonstrates antiproliferative effects against multiple myeloma both in vitro and
    Formula:C24H24N4O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:400.47

    Ref: TM-T79771

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Mcl-1 inhibitor 3

    CAS:
    Mcl-1 inhibitor 3 shows good pharmacokinetic properties and excellent in vivo efficacy without toxicity.Mcl-1 inhibitor 3 is a highly potent and orally activate
    Formula:C40H52ClF2N5O7S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:820.39

    Ref: TM-T11972

    25mg
    1.369,00€
  • GR-1405


    GR-1405 is a human monoclonal antibody (mAb) that targets B7-H1/PD-L1/CD274. It enhances the antitumor immune response mediated by cytotoxic T lymphocytes (CTL) against tumor cells expressing PD-L1. GR-1405 is applicable in research related to lymphomas and solid tumors.
    Colore e forma:Odour Liquid

    Ref: TM-T9901A-1689

    1mg
    Prezzo su richiesta
    5mg
    Prezzo su richiesta
  • Thalidomide-O-C6-NH2

    CAS:
    Thalidomide-O-C6-NH2 is a synthesized E3 ligase ligand-linker conjugate used in the PROTAC dTAG-13, a degrader of FKBP12F36V and BET[1].
    Formula:C19H23N3O5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:373.4

    Ref: TM-T18825

    100mg
    Prezzo su richiesta
    500mg
    Prezzo su richiesta
  • Human PD-L1 inhibitor IV

    CAS:
    PD-L1 inhibitor IV, a polypeptide, competitively blocks hPD-1 with a Kd of 1.38 μM, preventing hPD-1/hPD-L1 interaction.
    Formula:C80H113N25O27
    Colore e forma:Solid
    Peso molecolare:1856.932

    Ref: TM-T39588

    5mg
    202,00€
  • RIPK1-IN-17

    CAS:
    RIPK1-IN-17 is a dual inhibitor of RIPK1 and RIPK3 inhibits necrosis by inhibiting phosphorylation of RIPK1, RIPK3 and MLKL,in a tnf-induced inflammation model.
    Formula:C26H19F4N3O3S
    Purezza:95.22%
    Colore e forma:Solid
    Peso molecolare:529.51

    Ref: TM-T81268

    1mg
    50,00€
    5mg
    99,00€
    10mg
    152,00€
    25mg
    250,00€
    50mg
    369,00€
  • FPR1 antagonist 1


    Compound 24a, an FPR1 antagonist, demonstrates potent inhibition of the formyl peptide receptor 1 (FPR1) with an IC50 value of 25 nM.
    Formula:C25H28O5
    Colore e forma:Solid
    Peso molecolare:408.49

    Ref: TM-T79781

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • 7-Methoxy-1-tetralone

    CAS:
    7-Methoxy-1-tetralone may have insecticidal activity.
    Formula:C11H12O2
    Purezza:99.85% - 99.89%
    Colore e forma:White Crystal
    Peso molecolare:176.21

    Ref: TM-Fr12275

    2g
    33,00€
    1mL*10mM (DMSO)
    34,00€
  • Cefatrizine

    CAS:
    Cefatrizine inhibits eEF-2 kinase, affecting apoptosis, autophagy, and ER stress in cancers.
    Formula:C18H18N6O5S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:462.5

    Ref: TM-T26973

    25mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
    100mg
    Prezzo su richiesta
  • PROTAC FLT-3 degrader 1

    CAS:
    PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 degrader of internal tandem duplication (ITD)(IC50 0.6 nM),with anti-proliferative activity.
    Formula:C52H61N9O9S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1020.23

    Ref: TM-T12555

    100mg
    Prezzo su richiesta
    500mg
    Prezzo su richiesta
  • ARD-61

    CAS:
    ARD-61: potent PROTAC, degrades AR/PR in AR+ cancers, triggers apoptosis, inhibits tumor growth in mice.
    Formula:C61H71ClN8O7S
    Colore e forma:Solid
    Peso molecolare:1095.8

    Ref: TM-T39853

    25mg
    1.369,00€
  • FLT3-IN-29


    FLT3-IN-29 (Compound MY-10) is an FLT3 inhibitor with IC50 values of 6.5 nM and 10.3 nM for FLT3-ITD and FLT3-D835Y mutants, respectively. It induces cell cycle arrest at the G0/G1 phase and effectively triggers apoptosis (Apoptosis). Additionally, FLT3-IN-29 reduces reactive oxygen species (ROS) and mitochondrial membrane potential (MMP), displaying anti-leukemic properties.
    Formula:C25H30N6O2
    Colore e forma:Solid
    Peso molecolare:446.545

    Ref: TM-T204337

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • MKC-1

    CAS:
    MKC-1 (Ro-31-7453) is an oral bisindolylmaleimide inhibitor that disrupts tubulin polymerization, potentially halting cancer cell division.
    Formula:C22H16N4O4
    Purezza:99.63% - 99.85%
    Colore e forma:Solid
    Peso molecolare:400.39

    Ref: TM-T9831

    500mg
    Prezzo su richiesta
    1mg
    54,00€
    5mg
    118,00€
    1mL*10mM (DMSO)
    127,00€
    10mg
    168,00€
    25mg
    293,00€
    50mg
    423,00€
    100mg
    588,00€
  • PROTAC GPX4 degrader-1

    CAS:
    PROTAC GPX4 Degrader-1 (DC-2) is a PROTAC-based compound that efficiently degrades GPX4, demonstrating a degradation concentration (DC 50) of 0.03 μM in HT1080
    Formula:C50H57ClN10O10
    Colore e forma:Solid
    Peso molecolare:993.5

    Ref: TM-T74796

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • L-threo-PPMP

    CAS:
    L-threo-PPMP blocks GlcT, curbs glycosphingolipid creation, and triggers cell death, showing anti-cancer effects.
    Formula:C29H50N2O3
    Colore e forma:Solid
    Peso molecolare:474.73

    Ref: TM-T39478

    5mg
    873,00€
  • XZ739

    CAS:
    XZ739: Cereblon-based PROTAC, degrades BCL-XL (DC50 2.5 nM in MOLT-4, 16hr), induces caspase apoptosis.
    Formula:C65H76ClF3N8O12S3
    Colore e forma:Solid
    Peso molecolare:1349.99

    Ref: TM-T39909

    5mg
    1.153,00€
    10mg
    1.900,00€
  • 2,2'-Dihydroxy chalcone

    CAS:
    2,2'-Dihydroxy chalcone inhibits β-glucuronidase (IC50=1.6 μM) and lysozyme (IC50=1.4 μM), and fights E. coli, S. fowleri, S. albicans, S. aureus.
    Formula:C15H12O3
    Purezza:99.70%
    Colore e forma:Solid
    Peso molecolare:240.25

    Ref: TM-TN7224

    1mg
    85,00€
    5mg
    168,00€
    10mg
    240,00€
    25mg
    371,00€
    50mg
    513,00€
    100mg
    687,00€
    200mg
    928,00€
  • Pyridinium bisretinoid A2E

    CAS:
    Pyridinium bisretinoid A2E (A2E) is a fluorescent molecule isolated from the lipofuscin of retinal pigment epithelium, a weak photosensitizer.
    Formula:C42H58NO
    Purezza:83.65%
    Colore e forma:Solid
    Peso molecolare:592.92

    Ref: TM-T74051

    1mg
    839,00€
  • HDAC-IN-84


    HDAC-IN-84 (compound 4a) is a potent HDAC inhibitor with IC50 values of 0.0045, 0.015, 0.013, 0.038, 5.8, and 26 μM for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC11, respectively. It effectively inhibits the proliferation of leukemia cells without causing toxicity.
    Formula:C17H21N3O5S
    Colore e forma:Solid
    Peso molecolare:379.431

    Ref: TM-T204799

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • IDH1/2-IN-1


    IDH1/2-IN-1 (Compound 6b) is a dual inhibitor of IDH1(R132H)/IDH2(R140Q) with IC50 values of 0.22 μM and 1.6 μM, respectively. This compound effectively inhibits tumor growth by suppressing tumor cell proliferation and activating antioxidative enzymes to enhance host defense. Additionally, IDH1/2-IN-1 reduces inflammation and promotes apoptosis, demonstrating significant anti-tumor activity. It is also utilized in leukemia research.
    Colore e forma:Odour Solid

    Ref: TM-T88989

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Tubulin polymerization-IN-67


    Tubulin polymerization-IN-67 (Compound 5h) serves as an inhibitor of microtubule protein polymerization at the colchicine binding site, exhibiting an IC50 value of 2.92 μM. It effectively inhibits the proliferation of various cancer cell lines including HT29, A549, U2OS, MG-63, and HeLa, with IC50 values ranging from 0.12 to 4.13 μM. Additionally, Tubulin polymerization-IN-67 induces cell cycle arrest at the G2/M phase and triggers apoptosis in U2OS cells. It also inhibits cell migration in A549 and reduces mitochondrial membrane potential (MMP) while increasing intracellular ROS levels, thereby suppressing angiogenesis in HUVEC cells. Furthermore, this compound demonstrates antitumor activity in mice.
    Colore e forma:Odour Solid

    Ref: TM-T89235

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Antagonist G

    CAS:
    Antagonist G is an anticancer peptide and is also a broad spectrum neuropeptide growth factor antagonist.
    Formula:C49H66N12O6S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:951.19

    Ref: TM-T20481

    25mg
    858,00€
  • NA-Ir

    CAS:
    NA-Ir is a ferroptosis (Ferroptosis) inducer that targets mitochondrial DNA (mtDNA) and activates the cGAS-STING pathway to stimulate ferritin autophagy (). It also induces the production of reactive oxygen species (ROS) through photodynamic therapy (PDT), depletes glutathione (GSH), and downregulates glutathione peroxidase 4 (GPX4), thereby triggering lipid peroxidation and ferroptosis. NA-Ir exhibits enhanced anticancer activity under light exposure and selectively inhibits cancer cells with high H2S content.
    Formula:C49H36F6IrN8O4P
    Colore e forma:Solid
    Peso molecolare:1138.04

    Ref: TM-T200615

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Sanggenon G

    CAS:
    Sanggenon G inhibits XIAP by binding its BIR3 domain; affinity is 34.26 μM, boosting caspase activation.
    Formula:C40H38O11
    Colore e forma:Solid
    Peso molecolare:694.72

    Ref: TM-T73876

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Vinepidine sulfate

    CAS:
    Vinepidine (LY-119863) sulfate, a derivative of vincristine, exhibits antitumor activity .
    Formula:C46H58N4O13S
    Colore e forma:Solid
    Peso molecolare:907.04

    Ref: TM-T88271

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • AS-99 TFA


    AS-99 TFA: potent ASH1L inhibitor, IC50=0.79 μM, combats leukemia, inhibits cell growth, induces apoptosis.
    Colore e forma:Solid

    Ref: TM-T36978

    5mg
    482,00€
    10mg
    818,00€
  • Pantinin-1

    CAS:
    Pantinin-1 is an antimicrobial peptide found in the venom of the emperor scorpion (Pandinus imperator). This compound exhibits strong antibacterial activity against Gram-positive bacteria and fungi, but has weaker effects on Gram-negative bacteria. Additionally, Pantinin-1 demonstrates very low hemolytic activity on human red blood cells and possesses anticancer properties, specifically inducing apoptosis in tumor cells.
    Formula:C75H119N17O18
    Colore e forma:Solid
    Peso molecolare:1546.85

    Ref: TM-TP2756

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • HDAC-IN-79


    HDAC-IN-79 (compound 4) is an orally active dual inhibitor of xanthine oxidase and HDAC, exhibiting potent anti-hyperuricemia and antitumor activities in vivo (Xanthine oxidase: IC50=6.6 nM; HDAC1: IC50=134 nM; HDAC2: IC50=284 nM; HDAC3: IC50=173 nM; HDAC6: IC50=1.32 nM). Among leukemia cells, it is most effective in inhibiting the growth of HL60 cells (IC50=0.706 μM) and induces both apoptosis and autophagy. HDAC-IN-79 also modulates the expression levels of biomarkers associated with intracellular HDAC inhibition.
    Colore e forma:Odour Solid

    Ref: TM-T200527

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • c-MYC/BCL2 ligand 1 iodide


    c-MYC/BCL2 ligand 1 iodide is a dual-target ligand that specifically interacts with the G-quadruplex (G4) regions of the c-MYC and Bcl-2 promoters, exhibiting Kd values of 0.90 μM for c-MYCG4 and 0.56 μM for Bcl-2G4. It works by binding to these G4-forming sequences to inhibit transcription of the c-MYC and Bcl-2 genes, leading to reduced protein expression. This compound effectively suppresses MCF-7 cell proliferation and migration, induces G1 phase cell cycle arrest, and triggers apoptosis. Additionally, it significantly hampers tumor growth in the 4T1 homogenous model with negligible toxicity. c-MYC/BCL2 ligand 1 iodide is applicable in breast cancer research.
    Colore e forma:Odour Solid

    Ref: TM-T211076

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Epoprostenol sodium

    CAS:
    Epoprostenol sodium (Prostaglandin I2 sodium salt) is a vasodilator and a synthetic prostacyclin that can be used to study pulmonary hypertension.
    Formula:C20H31NaO5
    Purezza:98%
    Colore e forma:White Crystalline Powder
    Peso molecolare:374.45

    Ref: TM-T15238

    1mg
    239,00€
    5mg
    1.018,00€
    10mg
    1.783,00€
    25mg
    4.365,00€
  • Aloeresin G

    CAS:
    Aloeresin G, a chromone glycoside isolated from Aloe, exhibits a moderate inhibitory effect on TNFα-induced NF-κB transcriptional activity, evidenced by an IC50
    Formula:C29H30O10
    Colore e forma:Solid
    Peso molecolare:538.54

    Ref: TM-T79961

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • QZ2135


    QZ2135 (compound 20) is a PROTAC degrader that specifically targets RET and exhibits antitumor activity in vivo within a Ba/F3-KIF5B-RET-G810C xenograft mouse model. The compound demonstrates degradation activity with DC50 values of 4.7 nM (WT), 17.2 nM (V804M), and 73.8 nM (G810C) when targeting KIF5B-RET. QZ2135 is composed of the target protein ligand (red part) RETligand-3, the E3 ligase ligand (blue part) Lenalidomide-F, and the PROTAC Linker (black part) 7-Iodohept-1-yne, wherein the target protein ligand combined with the linker forms the conjugate RETLigand-Linker Conjugate-1.
    Formula:C53H54N12O4
    Colore e forma:Solid
    Peso molecolare:923.07

    Ref: TM-T205359

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Z-Asp-CH2-DCB

    CAS:
    Z-Asp-CH2-DCB is an irreversible inhibitor of broad spectrum caspase.
    Formula:C20H17Cl2NO7
    Purezza:99.08%
    Colore e forma:Solid
    Peso molecolare:454.26

    Ref: TM-T13378

    25mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
    10mg
    43,00€
  • JAK05


    JAK05 exhibits inhibitory activity against Helicobacter pylori, effectively suppressing strains J63, J196, and J107, with a MIC of 3-5 µg/mL. It shows affinity for binding to H+/K+-ATPase, COX-1/2, TNF-α, and PGE2, and possesses antioxidant and anti-inflammatory properties. In a rat model of ethanol-induced gastric ulcers, JAK05 demonstrates anti-ulcer activity.
    Formula:C27H27ClN4O9S
    Colore e forma:Solid
    Peso molecolare:619.043

    Ref: TM-T204688

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Targaprimir-96

    CAS:
    Targaprimir-96 is a potent microRNA-96 (miR-96) processing inhibitor.
    Formula:C77H102N18O7
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1391.75

    Ref: TM-T13085

    25mg
    1.369,00€
  • MS41

    CAS:
    MS41 is a selective eleven-nineteen leukemia (ENL) PROTAC degrader, with DC50s values of 3.50 nM (MV4;11), 2.84 nM (SEMK2), 3.03 nM (Jurkat), and 26.58 nM (KASUMI1). This compound effectively inhibits the growth of ENL-dependent leukemia cells, induces G1 cell cycle arrest, and increases cellular apoptosis (Apoptosis). Additionally, MS41 reduces chromatin occupancy related to ENL-mediated transcription elongation mechanisms and suppresses the expression of oncogenes and the progression of leukemia.
    Formula:C56H70N8O9S
    Colore e forma:Solid
    Peso molecolare:1031.27

    Ref: TM-T200591

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Ac-FEID-CMK


    Ac-FEID-CMK: Potent inhibitor for zebrafish GSDMEb, reduces pyroptosis, and lessens septic AKI.
    Formula:C27H37ClN4O9
    Colore e forma:Solid
    Peso molecolare:597.06

    Ref: TM-T76251

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • ChoKα inhibitor-3


    ChoKα Inhibitor-3, a sulfur-containing choline kinase inhibitor, effectively inhibits HChoK α1 with an IC50 value of 0.66 μM and possesses the capability to
    Formula:C50H54Br2Cl2N4S2
    Colore e forma:Solid
    Peso molecolare:1005.83

    Ref: TM-T75024

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Trichostatin C

    CAS:
    Trichostatin C, a natural glycosylated hydroxamate, is a histone deacetylase inhibitor with antifungal properties and can induce cell differentiation.
    Formula:C23H32N2O8
    Colore e forma:Solid
    Peso molecolare:464.515

    Ref: TM-T35825

    500µg
    652,00€
  • Thalidomide-O-amido-PEG3-C2-NH2

    CAS:
    Thalidomide-O-amido-PEG3-C2-NH2 is a cereblon ligand-linker for PROTACs with a 3-unit PEG.
    Formula:C23H30N4O9
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:506.51

    Ref: TM-T17915

    100mg
    Prezzo su richiesta
    500mg
    Prezzo su richiesta
  • [1,1'-Biphenyl]-3-amine

    CAS:
    [1,1'-Biphenyl]-3-amine is an inhibitor of MAO-A and MAO-B and can inhibit the cell viability of HT-29, HEK 293, and MCF-7 cells.
    Formula:C12H11N
    Purezza:99.78%
    Colore e forma:Solid
    Peso molecolare:169.22

    Ref: TM-TN9371

    50mg
    39,00€
    100mg
    52,00€
  • ZYH-23


    ZYH-23 is a potent inhibitor of necroptosis. It targets HSP90 to inhibit the phosphorylation of RIPK1, RIPK3, and MLKL, effectively blocking programmed cell necrosis.
    Formula:C41H50N4O3
    Colore e forma:Solid
    Peso molecolare:646.38829

    Ref: TM-T207337

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • UNC10245380


    UNC10245380 is a CIB1 inhibitor with an IC50 of 8 μM. It also inhibits the phosphorylation of AKT and ERK while upregulating the expression of TRAIL-R1/D5. UNC10245380 specifically kills cancer cells that are dependent on CIB1, demonstrating its potential value in the development of CIB1 probes and cancer research.
    Colore e forma:Odour Solid

    Ref: TM-T89144

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • PD1-PDL1-IN 1 TFA


    PD1-PDL1-IN 1 TFA (compound 16) is a potent inhibitor of programmed cell death 1 (PD-1), functioning as an immune modulator [1].
    Formula:C16H24F3N7O8
    Colore e forma:Solid
    Peso molecolare:499.4

    Ref: TM-T73630

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • TMX1

    CAS:
    TMX1 is a molecular glue degrader targeting BRD4, selectively recruiting the ubiquitin ligase CUL4-DCAF16 complex to BRD4 (BD2.
    Formula:C26H28N4O3S
    Purezza:99.57%
    Colore e forma:Solid
    Peso molecolare:476.59

    Ref: TM-T75139

    5mg
    863,00€
  • β-Glucuronide-dPBD-PEG5-NH2 TFA

    CAS:
    β-Glucuronide-dPBD-PEG5-NH2 TFA is a β-glucuronide-linked pyrrolobenzodiazepine dimer employed in the synthesis of the antibody-drug conjugate (ADC) cIRCR201-
    Formula:C80H102F3N7O37
    Colore e forma:Solid
    Peso molecolare:1810.69

    Ref: TM-T74438

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Fuscin

    CAS:
    Fuscin, a quinonoid from O. fuscum, inhibits ADP/ATP translocase, depletes glutathione, disrupts NADH oxidation, and blocks MIP-1α/CCR5 binding (IC50: 21µM).
    Formula:C15H16O5
    Colore e forma:Solid
    Peso molecolare:276.288

    Ref: TM-T37714

    5mg
    2.025,00€
  • Thalidomide-O-C7-NH2

    CAS:
    Thalidomide-O-C7-NH2 is a cereblon ligand-linked E3 ligase for PROTAC use.
    Formula:C20H25N3O5
    Colore e forma:Solid
    Peso molecolare:387.436

    Ref: TM-T39511

    25mg
    1.369,00€
  • Trilexium

    CAS:
    Trilexium (TRX-E-009-1), a third-generation benzopyran structurally related to TRX-E-002-1, increases p21 protein expression, induces apoptosis, depolymerizes microtubules, and demonstrates broad anti-cancer activity [1] [2].
    Formula:C24H23FO6
    Colore e forma:Solid
    Peso molecolare:426.43

    Ref: TM-T87565

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Azalamellarin N

    CAS:
    Azalamellarin N is a pyroptosis inhibitor that exhibits varying inhibitory effects on different pyroptosis inducers. It functions by targeting molecules upstream of NLRP3 inflammasome activation, instead of directly affecting the components of the NLRP3 inflammasome. Its inhibitory potency against various inducers is ranked as follows: Nigericin > R837 [1].
    Formula:C28H22N2O7
    Colore e forma:Solid
    Peso molecolare:498.48

    Ref: TM-T85784

    25mg
    2.840,00€
    50mg
    4.104,00€
    100mg
    5.169,00€
  • PBE-AMF


    PBE-AMF is a prodrug that activates H2O2 and exhibits anticancer activity. It impedes tumor proliferation by inhibiting DNA synthesis, reducing ATP levels, inducing cell death (apoptosis), and blocking the cell cycle. PBE-AMF effectively and selectively inhibits the proliferation of MDA-MB-231 cells (IC50=6.4 μM) while sparing non-cancerous MCF-10A cells.
    Colore e forma:Odour Solid

    Ref: TM-T88991

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • A947

    CAS:
    A947 is a potent and selective SMARCA2 PROTAC that induces the degradation of SMARCA2, with significant antitumor activity in SMARCA4-mutant NSCLC cells.
    Formula:C61H76N12O7S
    Purezza:98.84%
    Colore e forma:Solid
    Peso molecolare:1121.4

    Ref: TM-T74686

    1mg
    1.083,00€
    5mg
    2.311,00€
    10mg
    3.465,00€
  • ZZM-1220


    ZZM-1220, a covalent inhibitor of histone lysine methyltransferase G9a/GLP, exhibits IC50 values of 458 nM for G9a and 924 nM for GLP.
    Formula:C25H29N5O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:447.53

    Ref: TM-T79776

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Boc-Asp(OBzl)-CMK

    CAS:
    Boc-Asp(OBzl)-CMK, an inhibitor of IL-1 converting enzyme (ICE, caspase1), prevents the death of CHP100 neuroblastoma cells and inhibits IL-1β release induced by the viral coat protein [1].
    Formula:C17H22ClNO5
    Colore e forma:Solid
    Peso molecolare:355.81

    Ref: TM-T85867

    25mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
    100mg
    Prezzo su richiesta