Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(11 prodotti)
- Caspasi(144 prodotti)
- FOXO1(3 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(139 prodotti)
- PDK(9 prodotti)
- PERK(26 prodotti)
- Chinasi di serina/treonina(18 prodotti)
- Survivin(14 prodotti)
- TNF(93 prodotti)
- c-RET(62 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 6070 prodotti di "Apoptosi"
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Fosbretabulin [free base]
CAS:<p>Fosbretabulin is a natural cis-stilbene that interferes with cellular tubulin dynamics and selectively destroys tumor blood vessels.</p>Formula:C18H21O8PColore e forma:SolidPeso molecolare:396.33Aloeresin G
CAS:Aloeresin G, a chromone glycoside isolated from Aloe, exhibits a moderate inhibitory effect on TNFα-induced NF-κB transcriptional activity, evidenced by an IC50Formula:C29H30O10Colore e forma:SolidPeso molecolare:538.54QZ2135
<p>QZ2135 (compound 20) is a PROTAC degrader that specifically targets RET and exhibits antitumor activity in vivo within a Ba/F3-KIF5B-RET-G810C xenograft mouse model. The compound demonstrates degradation activity with DC50 values of 4.7 nM (WT), 17.2 nM (V804M), and 73.8 nM (G810C) when targeting KIF5B-RET. QZ2135 is composed of the target protein ligand (red part) RETligand-3, the E3 ligase ligand (blue part) Lenalidomide-F, and the PROTAC Linker (black part) 7-Iodohept-1-yne, wherein the target protein ligand combined with the linker forms the conjugate RETLigand-Linker Conjugate-1.</p>Formula:C53H54N12O4Colore e forma:SolidPeso molecolare:923.07Tulinercept
CAS:Tulinercept (OPRX-106), a monoclonal antibody, may be utilized in a range of biochemical research applications [1].Colore e forma:LiquidOsajin
CAS:Osajin is the major bioactive iso avone present in the fruit of Maclura pomifera. It has antitumor, antioxidant, and anti-inflammatory activities.Formula:C25H24O5Purezza:98%Colore e forma:SolidPeso molecolare:404.46Targaprimir-96
CAS:Targaprimir-96 is a potent microRNA-96 (miR-96) processing inhibitor.Formula:C77H102N18O7Purezza:98%Colore e forma:SolidPeso molecolare:1391.75Aluminum phthalocyanine disulfonate disodium
CAS:AlPcS2 disodium: a photosensitizer for cancer therapies, isomeric mix, and used as a dye, reagent, and luminescent agent.Formula:C32H14AlClN8Na2O6S2Colore e forma:SolidPeso molecolare:779.05PPA-904 FA
PPA-904 FA is a cationic photosensitizer with antimicrobial activity that can be used to study chronic leg ulcers and diabetic foot ulcers.Formula:C29H43N3O2SPurezza:98%Colore e forma:SolidPeso molecolare:497.74β-Amyloid (1-40) (rat)
CAS:Rat form of the beta-Amyloid (1-40) peptideFormula:C190H291N51O57SPurezza:98%Colore e forma:SolidPeso molecolare:4233.76Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III)
CAS:Iron(III) compound induces ferroptosis in NB1 cells at 3μM, not apoptosis/necroptosis; inhibits various cancers, effective against drug-resistant NALM-6.Formula:C20H14ClFeN2O2Colore e forma:SolidPeso molecolare:405.64Fuscin
CAS:Fuscin, a quinonoid from O. fuscum, inhibits ADP/ATP translocase, depletes glutathione, disrupts NADH oxidation, and blocks MIP-1α/CCR5 binding (IC50: 21µM).Formula:C15H16O5Colore e forma:SolidPeso molecolare:276.288(±)-Silybin
CAS:(±)-Silybin, a racemate of Silybin, demonstrates a range of biological activities including inducing apoptosis and possessing hepatoprotective, antioxidant, anti-inflammatory, and anti-cancer properties [1] [2].Formula:C25H22O10Colore e forma:SolidPeso molecolare:482.44KWCN-41
CAS:KWCN-41, a RIPK1 inhibitor with 88 nM IC50, blocks necrosis, spares apoptosis, and is anti-inflammatory.Formula:C18H17N3O2Colore e forma:SolidPeso molecolare:307.35Thalidomide-O-PEG4-NHS ester
CAS:Thalidomide-O-PEG4-NHS ester is a polyethylene glycol (PEG)-based linker, commonly employed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].Formula:C28H33N3O13Purezza:98%Colore e forma:SolidPeso molecolare:619.57Anti-inflammatory agent 45
Compound 2v (Anti-inflammatory agent 45) demonstrates anticancer properties with direct inhibitory impacts on the proliferation of various blood malignancies,Formula:C25H22BrNO6Purezza:98%Colore e forma:SolidPeso molecolare:512.35Sec61-IN-4
Sec61-IN-4 (Compound 16b) is a potent Sec61 inhibitor with an IC50 value of 0.04 nM in U87-MG cells [1].Colore e forma:Odour SolidThiocolchicine
CAS:Thiocolchicine inhibits tubulin polymerization (IC50: 2.5 µM, Ki: 0.7 µM), induces apoptosis, and serves as an ADC cytotoxin.Formula:C22H25NO5SPurezza:98.19%Colore e forma:SolidPeso molecolare:415.5ARV-393 HCl
ARV-393 HCl is an orally active and potent PROTAC targeting BCL6 with antitumor activity for the study of non-Hodgkin's lymphoma.Formula:C46H54Cl2FN9O7Purezza:99.79%Colore e forma:SolidPeso molecolare:934.88PROTAC ATR degrader-2
CAS:PROTAC ATR degrader-2 (Compound 8i) serves as a PROTAC degrader targeting ATR, effectively degrading it in acute myeloid leukemia (AML) cell lines MV-4-11 and MOLM-13, with DC50 values of 22.9 and 34.5 nM, respectively. This compound induces apoptosis and inhibits the proliferation of AML cells. Additionally, PROTAC ATR degrader-2 demonstrates favorable pharmacokinetic properties and potent antitumor activity in a mouse model of AML.Formula:C40H41N9O6Peso molecolare:743.81Jacaric Acid
CAS:Conjugated 18-C ω-6 fatty acid from Jacaranda seeds, induces cancer cell apoptosis via oxidative stress; metabolizes to cytotoxic CLA.Formula:C18H30O2Colore e forma:SolidPeso molecolare:278.436Sym029
Sym029 is a human IgG monoclonal antibody (mAb) that targets TNFRSF5/CD40. It is applicable for cancer research. The suggested isotype control is Human IgG1 kappa, Isotype Control.SF1126
CAS:SF1126 is a first-in-class PI3K/BRD4 inhibitor and RGDS-conjugated LY294002 prodrug, enhancing solubility and targeting tumor integrins.Formula:C39H48N8O14Purezza:98%Colore e forma:SolidPeso molecolare:852.84HL435
HL435 is a heterobifunctional molecule that degrades BRD4 by linking with JQ1, with DC50 values of 11.9 nM and 21.9 nM in MDA-MB-231 and MCF-7 cells, respectively. It inhibits the proliferation of MDA-MB-231, MCF-7, 22Rv1, and A549 cells, arrests the cell cycle, and induces apoptosis. Additionally, HL435 exhibits antitumor activity in mouse models.Formula:C47H48BrClF3N7O7SPeso molecolare:1025.21599DRI-C21041 (DIEA)
DRI-C21041 DIEA serves as an inhibitor of CD40/CD40L interaction, exhibiting an inhibitory concentration (IC50) of 0.31 μM.Formula:C38H40N4O7SColore e forma:SolidPeso molecolare:696.81DHFR-IN-23
DHFR-IN-23 (compound 5) is a dual inhibitor of DNA binders/DHFR, exhibiting an IC50 value of 0.08 μM against hDHFR. It serves as an apoptosis inducer and is applicable in research on ER+ breast cancer.Colore e forma:Odour SolidHDAC-IN-57
CAS:HDAC-IN-57 is an orally active pan-inhibitor of histone deacetylase (HDAC), inhibiting HDAC1, HDAC2, HDAC6, and HDAC8 with IC50 values of 2.07 nM, 4.71 nM, 2.4Formula:C21H19N3O4Purezza:98.62%Colore e forma:SoildPeso molecolare:377.39Mcl-1 inhibitor 14
Compound (Ra)-10, also known as Mcl-1 inhibitor 14, is a potent inhibitor of myeloid cell leukemia-1 (MCL-1), exhibiting a K_i of 0.018 nM, and holds potentialFormula:C39H41ClFN5O5SColore e forma:SolidPeso molecolare:746.29Suc-Ala-Leu-Pro-Phe-pNA
CAS:Suc-Ala-Leu-Pro-Phe-pNA (Suc-ALPF-pNA), a substrate for FK-506 binding protein (FKBP) [1], showcases the intricate interactions necessary for specificFormula:C33H42N6O9Peso molecolare:666.72BAY 1892005
CAS:BAY 1892005 is a p53 protein modulator that targets the p53 condenser for the study of diseases associated with misfolded p53 proteinFormula:C11H8ClFN2OSPurezza:99.42%Colore e forma:SoildPeso molecolare:270.71Fluorene
CAS:Compound PDK0379, with CAS No. 86-73-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0379 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C13H10Peso molecolare:166.21Anti-inflammatory agent 61
Compound 5b (Anti-inflammatory agent 61) is a potent anti-inflammatory agent that diminishes TNF-α expression in LPS-induced inflammation within RAW 264.7 cellsColore e forma:Odour SolidSB-1295
SB-1295, an orally active CDK9/T1 inhibitor with an IC50 of 0.17 μM, exhibits antiproliferative effects on HCT 116 and MIA PaCa-2 cells.Formula:C23H22ClNO6Purezza:98%Colore e forma:SolidPeso molecolare:443.88HC Toxin
CAS:HC Toxin: cyclic tetrapeptide, reversible HDAC inhibitor (IC50=30 nM), upregulates 15-lipoxygenase-1, induces fetal hemoglobin, from C. carbonum.Formula:C21H32N4O6Colore e forma:SolidPeso molecolare:436.50922-SLF
22-SLF is a PROTAC degrader that operates by FBXO22-dependent degradation of FK506 Binding Protein 12 (FKBP12) with a DC50 of 0.5 µM. Additionally, 22-SLF can degrade other endogenous proteins, such as BRD4 and the EML4-ALK fusion protein (EML4-ALK fusion protein).HDAC3-IN-2
HDAC3-IN-2 (compound 4i), a pyrazinyl hydrazide-based HDAC3 inhibitor with an IC50 of 14 nM, effectively targets triple-negative breast cancer cells.Formula:C16H21N5O2Purezza:98%Colore e forma:SolidPeso molecolare:315.37Trehalose-6,6'-dibehenate
CAS:Trehalose-6,6'-dibehenate, a bioactive glycolipid, is applicable for the preparation of vaccine adjuvant [1].Formula:C56H106O13Peso molecolare:987.43Emavusertib Phosphate
CAS:Emavusertib Phosphate (also known as CA-4948) is a potent inhibitor of IRAK4 and FLT3, exhibiting antitumor activity. In ABC DLBCL and AML cell lines, it demonstrates significant cellular efficacy. Furthermore, CA-4948 shows moderate to high selectivity across a panel of 329 kinases and possesses favorable ADME and PK profiles, including good oral bioavailability in mice, rats, and dogs. It achieves over 90% tumor growth inhibition in relevant tumor models and correlates excellently with in vivo PD modulation.Formula:C24H28N7O9PPeso molecolare:589.49Atacicept
CAS:Atacicept (TACI-Ig) is a homodimeric fusion protein that inhibits B cell stimulation.Purezza:97.9% (SDS-PAGE); 98.7% (SEC-HPLC) - 97.9% (SDS-PAGE); 98.7% (SEC-HPLC)Colore e forma:LiquidLWY713
LWY713 is a PROTAC-based FLT3 degrader (DC50=0.64 nM) that selectively induces FLT3 degradation through a cereblon and proteasome-dependent mechanism. It inhibits cell proliferation and causes G0/G1 phase arrest and apoptosis (apoptosis) in MV4-11 cells. In MV4-11 xenograft models, LWY713 demonstrates significant in vivo antitumor activity. The E3 ligase ligand and linker consist of Lenalidomide-Glycolic acid, while the target protein ligand's active control is NaproxenGilteritinib.Formula:C43H54N10O8Peso molecolare:838.41261BMS-986156
BMS-986156 is a fully humanized IgG1 agonist monoclonal antibody that targets the glucocorticoid-induced tumor necrosis factor receptor-related protein (GITR). It binds to GITR and enhances the activation of T effector cells while deactivating T regulatory cells. BMS-986156 is applicable for research in advanced solid tumors.Amiloride hydrochloride dihydrate
CAS:Amiloride hydrochloride dihydrate (Amiloride HCl dihydrate) is a pyrazine compound inhibiting SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride hydrochloride dihydrate is used in conjunction with DIURETICS to spare POTASSIUM loss.Formula:C6H8ClN7O·HCl·2H2OPurezza:99.07% - >99.99%Colore e forma:SolidPeso molecolare:302.12NFh-NMe-2
<p>NFh-NMe-2 is a photosensitizer that interacts with nitroreductase (nitroreductase) to generate singlet oxygen in tumor cells, exhibiting cytotoxicity in cancer cells and inducing apoptosis (apoptosis). In mouse models, NFh-NMe-2 demonstrates antitumor activity.</p>Formula:C32H33IN2OColore e forma:SolidPeso molecolare:588.522FF2049
FF2049 is a selective HDAC PROTAC degrader with a DC50 of 257 nM for HDAC1. It facilitates the ubiquitination and degradation of HDAC and promotes apoptosis (Apoptosis). FF2049 is applicable in research involving hematological and solid tumors.Formula:C31H38ClN7O7Colore e forma:SolidPeso molecolare:656.129AKT-IN-24
AKT-IN-24 (Compound M17) is an allosteric inhibitor of AKT exhibiting antitumor activity. In combination with Trametinib, it targets the AKT/mTOR and MEK/ERK signaling pathways while inhibiting epithelial-mesenchymal transition, resulting in a synergistic suppression effect on TNBC. This combination promotes apoptosis and inhibits cell proliferation and migration.Formula:C32H28N2O10Colore e forma:SolidPeso molecolare:600.572NLRP3-IN-60
<p>NLRP3-IN-60 (Compound 39) is an orally bioavailable inhibitor of NLRP3. It effectively suppresses pyroptosis in THP-1 cells with an IC50 of 13 nM and inhibits IL-1β release in human whole blood, exhibiting an IC50 of 225 nM.</p>Formula:C23H24F2N4O4SColore e forma:SolidPeso molecolare:490.5238-hydroxy Efavirenz
CAS:8-hydroxy Efavirenz, a main efavirenz metabolite by CYP2B6, causes apoptosis in rat neurons at 0.01 μM.Formula:C14H9ClF3NO3Colore e forma:SolidPeso molecolare:331.68PROTAC LZK-IN-1
CAS:<p>PROTAC LZK-IN-1 (Compound 21A) is a PROTAC molecule that targets the degradation of LZK (leucine zipper kinase, encoded by MAP3K13). At a concentration of 10 μM, PROTAC LZK-IN-1 facilitates the degradation of LZK and inhibits the expression of p53 and c-MYC, leading to reduced viability of global head and neck squamous cell carcinoma (HNSCC) cell lines. This compound is applicable in anticancer research.</p>Formula:C51H64F2N10O5SColore e forma:SolidPeso molecolare:967.18Mepacrine
CAS:Mepacrine (Erion) is an acridine derivative formerly widely used as an antimalarial.Formula:C23H30ClN3OPurezza:98.78%Colore e forma:Bright Yellow CrystalsPeso molecolare:399.96Ref: TM-T24449
5mg35,00€10mg56,00€25mg101,00€50mg166,00€100mg259,00€200mg376,00€1mL*10mM (DMSO)37,00€PAK4-IN-3
PAK4-IN-3 (compound 27e) is a PAK4 inhibitor exhibiting an IC50 of 10 nM and demonstrates antiproliferative effects on A549 cells with an IC50 of 0.61μM.Purezza:98%Colore e forma:Odour SolidTRF2-IN-1
<p>TRF2-IN-1 (compound F2) is a potent inhibitor of telomere repeat-binding factor 2 (TRF2). It exhibits antiproliferative activity and induces apoptosis. TRF2-IN-1 binds directly to the TRF2TRFH domain, selectively inhibiting TRF2 protein expression and telomere localization. Additionally, TRF2-IN-1 possesses anticancer properties and shows potential for osteosarcoma research.</p>Formula:C18H17BrO4Colore e forma:SolidPeso molecolare:377.229Thailanstatin D
CAS:<p>Thailanstatin D blocks AR-V7 splicing, disrupts U2AF65/SAP155 binding, and induces apoptosis in CRPC xenografts.</p>Formula:C28H41NO8Colore e forma:SolidPeso molecolare:519.635TrxR-IN-7
TrxR-IN-7 (14f) is a potent inhibitor of thioredoxin reductase (TrxR), with an IC50 value of 3.5 µM. It exhibits antiproliferative activity and can induce apoptosis and the production of reactive oxygen species (ROS).Formula:C22H21NO3Colore e forma:SolidPeso molecolare:347.407LD4172
CAS:LD4172 is a PROTAC degrader capable of degrading RIP kinase (RIPK1) with a DC50 in the nanomolar range. When used in combination with TNF-α, LD4172 can induce apoptosis in B16F10 cells. In mouse models, it demonstrates antitumor activity. (Pink: ligand for target protein; Black: linker; Blue: ligand for E3 ligase VHL)Formula:C61H75F3N10O7SColore e forma:SolidPeso molecolare:1149.37CSN5-IN-1
CSN5-IN-1 (compound Ac-11) serves as an inhibitor of CSN5, exhibiting IC50 values of 12.56 μM in FP assay and 19 μM in fluorescence assay. Additionally, it influences cellular protein expression by downregulating PD-L1 and upregulating NEDD8-Cul1.Formula:C17H22N2O2SColore e forma:SolidPeso molecolare:318.43TS-IN-5
TS-IN-5 (Compound 15) is an inhibitor of thymidylate synthase (TS). It induces apoptosis by modulating the proteins Bax, BCL-2, PI3K, and STAT1. TS-IN-5 exhibits antitumor activity against liver cancer, breast cancer, and colon cancer.Formula:C16H17N5OSColore e forma:SolidPeso molecolare:327.404Anticancer agent 157
Anticancer Agent 157 (compound 15) is a nitric oxide (NO) inhibitor with IC50 values of 0.62 μg/mL, exhibiting both anti-inflammatory and anticancer effects.Formula:C14H20O2Purezza:98%Colore e forma:SolidPeso molecolare:220.31C8 D-threo Ceramide (d18:1/8:0)
CAS:C8 D-threo Ceramide, a potent bioactive sphingolipid, is cytotoxic with IC50=17µM, enhances DNA fragmentation and pore formation, and activates CAPK.Formula:C26H51NO3Colore e forma:SolidPeso molecolare:425.698PK7088
CAS:PK7088, a pyrazole-based peptide, selectively reactivates mutant p53 to a conformation with wild-type characteristics, demonstrating anticancer activity inFormula:C14H13N3Purezza:98%Colore e forma:SolidPeso molecolare:223.27Tizanidine
CAS:Tizanidine, an α2-adrenergic receptor agonist, suppresses the release of neurotransmitters from central nervous system (CNS) noradrenergic neurons.Formula:C9H8ClN5SPurezza:99.11%Colore e forma:White SolidPeso molecolare:253.71Thalidomide-O-PEG4-Boc
CAS:Thalidomide-O-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].Formula:C28H38N2O11Purezza:98%Colore e forma:SolidPeso molecolare:578.61Citatuzumab bogatox
CAS:Citatuzumab bogatox is a recombinant immunotoxin targeting EpCAM with the toxin bouganin, inducing apoptosis in EpCAM-positive tumors.Colore e forma:Liquid6-Formylpterin
CAS:<p>6-Formylpterin (Pterin-6-aldehyde) is an inhibitor of Xanthine Oxidase, which induces ROS generation and apoptosis in HL-60 cells.</p>Formula:C7H5N5O2Purezza:98%Colore e forma:SolidPeso molecolare:191.15Lacto-N-neotetraose
CAS:LNnT is a metabolite that reduces IL-8, has anti-inflammatory effects, and aids in wound healing.Formula:C26H45NO21Colore e forma:SolidPeso molecolare:707.63Ref: TM-T75694
1mg55,00€5mg122,00€10mg177,00€25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaBr-DAPI
CAS:IST5-002 (N6-Benzyladenosine-5'-phosphate) is a Stat5a/b inhibitor with anticancer activity and is used in cancer research.Formula:C16H14BrN5Purezza:100%Colore e forma:SolidPeso molecolare:356.22Isoalantolactone
CAS:Formula:C15H20O2Purezza:>98.0%(HPLC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:232.32Primidone (Standard)
CAS:Primidone (Standard) is the standard substance of Primidone, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Primidone (NCI-C56360) is a potent anticonvulsant agent. It is a neuronal voltage-gated sodium channel blocker and has value in the study of epilepsy, essential tremor, and psychiatric disorders.Formula:C12H14N2O2Peso molecolare:218.25Necrostatin 2 S enantiomer
CAS:Necrostatin 2 S enantiomer is the S enantiomer of Necrostatin 2Formula:C13H12ClN3O2Purezza:98%Colore e forma:SolidPeso molecolare:277.71Lestaurtinib
CAS:Lestaurtinib (CEP 701) is a FLT3 inhibitor that inhibits the phosphorylation of RPTKs and can be used to study leukemia.Formula:C26H21N3O4Purezza:99.17%Colore e forma:Off-White SolidPeso molecolare:439.46PARG-IN-4
CAS:PARG-IN-4 (compound A) is an orally active and cell-membrane permeable PARG inhibitor (EC50=1.9 nM) that inhibits tumour growth in mice with antitumour .Formula:C20H25F2N7O2S2Purezza:98.51%Colore e forma:SolidPeso molecolare:497.59Propylparaben sodium
CAS:Propylparaben sodium, a plant-based preservative used in cosmetics, pharma, and food, hinders follicle growth and sperm health.Formula:C10H12NaO3Colore e forma:SolidPeso molecolare:203.193Vandetanib
CAS:Formula:C22H24BrFN4O2Purezza:>98.0%(T)(HPLC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:475.36Buparlisib Hydrochloride
CAS:Buparlisib Hydrochloride is an inhibitor of pan-class I PI3K (IC50: 52 nM/166 nM/116 nM/262 nM for p110α/p110β/p110δ/p110γ, respectively).Formula:C18H22ClF3N6O2Purezza:98.94%Colore e forma:SolidPeso molecolare:446.85PB28 dihydrochloride
CAS:ZD-6888 Hydrochloride (ZD-6888 HCl) is an angiotensin II antagonist that mediates AII receptor blockade and induces AII-mediated inhibition of renin release.Formula:C24H40Cl2N2OPurezza:99.97%Colore e forma:SolidPeso molecolare:443.49FPA-124
CAS:FPA-124 is a cell-permeable copper complex that acts as a selective Akt (protein kinase B) inhibitor to induce apoptosis in a variety of cancer cell lines.Formula:C11H9Cl2CuN3O2SPurezza:95.04%Colore e forma:SolidPeso molecolare:381.73Thalidomide-Piperazine 5-fluoride
CAS:Thalidomide-Piperazine 5-fluoride: a cereblon ligand-linked E3 ligase via PROTAC tech.Formula:C17H17FN4O4Colore e forma:SolidPeso molecolare:360.34Traumatic Acid
CAS:Traumatic Acid aids wound healing in plants by stimulating cell division to create a callus.Formula:C12H20O4Purezza:99.64%Colore e forma:SolidPeso molecolare:228.28Belinostat
CAS:Formula:C15H14N2O4SPurezza:>98.0%(HPLC)Colore e forma:White to Light yellow to Light orange powder to crystalPeso molecolare:318.35Thalidomide-O-C6-NH2 TFA
CAS:Thalidomide-O-C6-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate used in the PROTAC dTAG-13, a degrader of FKBP12F36V and BET[1].Formula:C21H24F3N3O7Purezza:98%Colore e forma:SolidPeso molecolare:487.432'-Aminoacetophenone
CAS:Compound Fr14273 is a natural product for research related to life sciences. The catalog number is Fr14273 and the CAS number is 551-93-9.Formula:C8H9NOPurezza:99.88%Colore e forma:Pale Yellow Solid Solid CrystallinePeso molecolare:135.17Monensin sodium salt (Standard)
CAS:Monensin sodium salt (Standard) is the standard substance of Monensin sodium salt, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Monensin sodium is an antiprotozoal agent produced by Streptomyces cinnamonensis.Monensin sodium salt (Monensin A sodium salt) causes a marked enlargement of the MVBs and regulates exosome secretionFormula:C36H61NaO11Peso molecolare:692.85M47
CAS:<p>M47 is a selective CRY1 (Cryptochrome 1) degradator that enhances nuclear degradation of CRY1, thereby extending the lifespan of p53 knockout mice.</p>Formula:C28H22ClNO4Colore e forma:SolidPeso molecolare:471.93Ref: TM-T74743
1mgPrezzo su richiesta5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaAmoscanate
CAS:Amoscanate is an antiparasitic agent. It is highly effective in animals against the four major species of schistosomes which infect humans.Formula:C13H9N3O2SColore e forma:SolidPeso molecolare:271.29GO-203
CAS:GO-203 is a useful organic compound for research related to life sciences. The catalog number is T35351 and the CAS number is 1222186-26-6.Formula:C89H171F3N52O21S2Colore e forma:SolidPeso molecolare:2426.81Iodoacetyl-LC-Biotin
CAS:Iodoacetyl-LC-Biotin (Iaa-Biotin) is a sulfhydryl-responsive probe that forms irreversible thioether bonds at alkaline pH, label protein cysteines.Formula:C18H31IN4O3SPurezza:97.47%Colore e forma:SolidPeso molecolare:510.43KS100
CAS:KS100 inhibits ALDH1A1, ALDH2, ALDH3A1, boosts ROS, triggers apoptosis, and has anti-cancer properties.Formula:C17H14Br3N3O2SPurezza:97.05%Colore e forma:SolidPeso molecolare:564.09KT-474
CAS:KT-474 (KYM-001) is a PROTAC degrader targeting IRAK4 with antitumor activity for the study of autoimmune diseases.Formula:C44H49F2N11O6Purezza:98.50% - 99.57%Colore e forma:SolidPeso molecolare:865.93Methoxyacetic acid
CAS:Methoxyacetic acid is an endogenous metabolite.Formula:C3H6O3Colore e forma:Less Liquid (Ntp 1992) Physical Description Colorless Liquid (Ntp 1992)Peso molecolare:90.08Ulipristal Acetate
CAS:Formula:C30H37NO4Purezza:>98.0%(T)(HPLC)Colore e forma:White to Yellow to Green powder to crystalPeso molecolare:475.63Venetoclax-d8
CAS:Venetoclax-d8 (ABT-199-d8) is a deuterated form of Venetoclax, a potent, selective, and orally active Bcl-2 inhibitor that induces autophagy and apoptosis.Formula:C45H42D8ClN7O7SColore e forma:SolidPeso molecolare:876.49GSK-843
CAS:GSK-843 (GSK'843) is a RIP3 inhibitor with analgesic activity, inhibits RIP3 expression, and can be used as an adjunctive treatment for inflammation.Formula:C19H15N5S2Purezza:99.18%Colore e forma:SolidPeso molecolare:377.49Terfenadine (Standard)
CAS:Terfenadine (Standard) is the standard substance of Terfenadine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Terfenadine ((±)-Terfenadine) is a prodrug that is metabolized by intestinal CYP3A4 to the active form fexofenadine, a selective histamine H1-receptor antagonist with antihistaminic and non-sedative effects.Formula:C32H41NO2Peso molecolare:471.67PBOX 6
CAS:PBOX 6 is a pyrrolo-1,5-benzoxazepine (PBOX) compound with anticancer and antitumor activity that inhibits the growth of breast cancer cells.Formula:C25H20N2O3Purezza:98.18% - 98.71%Colore e forma:SolidPeso molecolare:396.44Ref: TM-T16436
1mg59,00€5mg131,00€10mg187,00€25mg311,00€50mg462,00€100mg662,00€1mL*10mM (DMSO)140,00€Condurango glycoside A
CAS:Condurango glycoside A activates p53, induces ROS generation, up-regulates p53 expression, and triggers apoptosis as well as premature senescence associatedFormula:C53H78O17Colore e forma:SolidPeso molecolare:987.18Baohuoside I
CAS:Formula:C27H30O10Purezza:>95.0%(T)(HPLC)Colore e forma:White to Light yellow to Green powder to crystalPeso molecolare:514.53Amifostine thiol
CAS:Amifostine thiol (WR-1065), an active Amifostine metabolite, is a radioprotective cytoprotectant that activates p53 via JNK pathway.Formula:C5H14N2SPurezza:≥95.0%Colore e forma:SolidPeso molecolare:134.24SU11652
CAS:SU11652 is an effective and competitive receptor tyrosine kinase (RTK) inhibitor, including VEGFR, FGFR, PDGFR, and Kit.Formula:C22H27ClN4O2Purezza:99.14%Colore e forma:SolidPeso molecolare:414.93Prexasertib dimesylate
CAS:Prexasertib dimesylate is a selective CHK1 inhibitor with K i 0.9 nM, blocks CHK2 & RSK1, induces DNA breakage, and has potent anti-tumor effects.Formula:C20H27N7O8S2Colore e forma:SolidPeso molecolare:557.6Alantolactone
CAS:Formula:C15H20O2Purezza:>95.0%(GC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:232.32Prinaberel
CAS:Prinaberel (ERB-041) is an effective and selective ERβ agonist and >200-fold selective for ERβ.Formula:C15H10FNO3Purezza:97.1%Colore e forma:SolidPeso molecolare:271.24Triclabendazole (Standard)
CAS:Triclabendazole (Standard) is the standard substance of Triclabendazole, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Triclabendazole (CGA89317) has been used in trials studying Parasitic Disease.Formula:C14H9Cl3N2OSPeso molecolare:359.66
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