Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(5 prodotti)
- Caspasi(151 prodotti)
- FOXO1(2 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(105 prodotti)
- PDK(9 prodotti)
- PERK(26 prodotti)
- Chinasi di serina/treonina(18 prodotti)
- Survivin(14 prodotti)
- TNF(58 prodotti)
- c-RET(61 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 6043 prodotti di "Apoptosi"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Ginsenoside F2
CAS:Ginsenoside F2 halts breast CSCs growth, induces apoptosis via intrinsic pathway and impairs mitochondria.Formula:C42H72O13Purezza:99.04% - 99.3%Colore e forma:SolidPeso molecolare:785.01Ref: TM-T3916
1mg34,00€5mg65,00€10mg94,00€25mg137,00€50mg193,00€100mg286,00€500mg695,00€1mL*10mM (DMSO)92,00€LJH685
CAS:LJH685 is an effective pan-RSK inhibitor for RSK1/2/3 (IC50: 6/5/4 nM).Formula:C22H21F2N3OPurezza:99.13% - 99.78%Colore e forma:SolidPeso molecolare:381.42Ref: TM-T6877
1mg37,00€5mg88,00€10mg127,00€25mg240,00€50mg401,00€100mg603,00€200mg848,00€1mL*10mM (DMSO)87,00€Mocetinostat
CAS:Mocetinostat (MG0103) is an orally available HDAC inhibitor with most potency for HDAC1 (IC50: 0.15 μM), 2- to 10- fold selectivity against HDAC2/3/11.Formula:C23H20N6OPurezza:99% - 99.21%Colore e forma:SolidPeso molecolare:396.44AKT inhibitor VIII
CAS:AKT inhibitor VIII (AKTi-1/2) is a highly specific Akt1/2 inhibitor (IC50: 58/210 nM). The selectivity for Akt1 is higher about 36-fold than Akt3.Formula:C34H29N7OPurezza:98.31% - 98.65%Colore e forma:Pale Yellow SolidPeso molecolare:551.64Spautin-1
CAS:Spautin-1 is an autophagy inhibitor that can suppress the deubiquitination activity of ubiquitin-specific peptidase USP10 and USP13. Cost-effective and quality-assured.Formula:C15H11F2N3Purezza:97.69% - 98.99%Colore e forma:SolidPeso molecolare:271.26Ref: TM-T1937
2mg37,00€5mg52,00€10mg66,00€25mg111,00€50mg197,00€100mg298,00€200mg444,00€1mL*10mM (DMSO)58,00€Domatinostat tosylate
CAS:4SC-202 is a class I HDAC inhibitor targeting HDAC1/2/3; shows activity against LSD1. IC50: HDAC1 (1.20 μM), HDAC2 (1.12 μM), HDAC3 (0.57 μM).Formula:C30H29N5O6S2Purezza:97.35% - >99.99%Colore e forma:Solid PowderPeso molecolare:619.71Idasanutlin
CAS:Idasanutlin (Ro 5503781) (RG-7388) is an effective and specific p53-MDM2 inhibitor (IC50: 6 nM).Formula:C31H29Cl2F2N3O4Purezza:99.13% - 99.88%Colore e forma:SolidPeso molecolare:616.48Ref: TM-T6254
2mg38,00€5mg57,00€10mg90,00€25mg150,00€50mg215,00€100mg356,00€500mg837,00€1mL*10mM (DMSO)79,00€NADPH tetracyclohexanamine
CAS:NADPH tetracyclohexanamine (NADPH (tetracyclohexanamine)) is a cofactor and biological reducing agent.
Formula:C45H82N11O17P3Purezza:98.73% - 99.05%Colore e forma:SolidPeso molecolare:1142.12Tylvalosin tartrate
CAS:Tylvalosin tartrate (Acetylisovaleryltylosin Tartrate) is a macrolide antibiotic that can against Gram-positive bacteria.
Formula:C57H93NO25Purezza:99.25%Colore e forma:SolidPeso molecolare:1192.34Dehydroeffusol
CAS:Dehydroeffusol: anti-cancer, anxiolytic, sedative; halts gastric cancer growth via ER stress and apoptosis.Formula:C17H14O2Purezza:99.35%Colore e forma:SolidPeso molecolare:250.29cjoc42
CAS:Cjoc42 blocks gankyrin to prevent p53 reduction, aiding cancer prevention and DNA damage response.Formula:C20H21N3O5SPurezza:99.56%Colore e forma:SolidPeso molecolare:415.46Ref: TM-T27029
1mg60,00€5mg133,00€10mg193,00€25mg349,00€50mg522,00€100mg730,00€200mg982,00€1mL*10mM (DMSO)152,00€Rhosin hydrochloride
CAS:Rhosin hydrochloride is a specific inhibitor of the RhoA subfamily Rho GTPases.Cost-effective and quality-assured.Formula:C20H20Cl2N6OPurezza:97.33% - 98.92%Colore e forma:SolidPeso molecolare:431.318Ref: TM-T16745
1mg159,00€2mg40,00€5mg58,00€10mg97,00€25mg216,00€50mg406,00€100mg735,00€1mL*10mM (DMSO)64,00€5,7,4'-Trimethoxyflavone
CAS:5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.Formula:C18H16O5Purezza:97.53%Colore e forma:SolidPeso molecolare:312.324'-bromo-Resveratrol
CAS:4'-bromo-Resveratrolis a potent inhibitor of the deacetylases sirtuin 1 (SIRT1) and 3 (SIRT3)Formula:C14H11BrO2Purezza:99.00%Colore e forma:SolidPeso molecolare:291.14BIO-acetoxime
CAS:BIO-acetoxime (GSK-3 Inhibitor X) is a potent dual GSK3α/β inhibitor with IC50 of 10 nM, >240-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B.
Formula:C18H12BrN3O3Purezza:97.15%Colore e forma:SolidPeso molecolare:398.21SP-141
CAS:SP 141 is a MDM2 inhibitor.SP-141 promotes MDM2 auto-ubiquitination and degradation, with anticancer activity.Formula:C22H16N2OPurezza:98.01%Colore e forma:SolidPeso molecolare:324.38Thalidomide-NH-C2-PEG3-OH
CAS:Thalidomide-NH-C2-PEG3-OH (H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]amino]-) is an E3 ligaseFormula:C21H27N3O8Purezza:99.06%Colore e forma:SolidPeso molecolare:449.45Fraxetin
CAS:Fraxetin (7,8-dihydroxy-6-methoxy coumarin) has dual-antioxidative ,hepatoprotective and antihyperglycemic functions, it shows potent protective effects againstFormula:C10H8O5Purezza:98% - 99.59%Colore e forma:Light Yellow Crystalline FlakesPeso molecolare:208.17Scoulerine
CAS:Scoulerine is an inhibitor of ß-site amyloid precursor protein cleaving enzyme 1(BACE1).Formula:C19H21NO4Purezza:98.62%Colore e forma:SolidPeso molecolare:327.37ZM 336372
CAS:ZM 336372 is a potent and selective c-Raf inhibitor.Formula:C23H23N3O3Purezza:97.24% - 97.51%Colore e forma:SolidPeso molecolare:389.45Berbamine dihydrochloride
CAS:Berbamine dihydrochloride (Berbamine), a natural compound derived from the Berberis amurensis plant, has been shown to exhibit antitumor activity in several Ys.Formula:C37H42Cl2N2O6Purezza:95% - 99.99%Colore e forma:SolidPeso molecolare:681.65Ac-DEVD-pNA
CAS:Ac-DEVD-pNA is the preferred peptidic substrate for caspase-3.Formula:C26H34N6O13Purezza:>99.99%Colore e forma:WhitePeso molecolare:638.58Ref: TM-T7816
2mg34,00€5mg57,00€10mg75,00€25mg160,00€50mg231,00€100mg335,00€200mg477,00€1mL*10mM (DMSO)79,00€HA14-1
CAS:HA14-1, a Bcl-2/Bcl-XL antagonist, is a non-peptidic ligand of a Bcl-2 surface pocket (IC50: ~9 μM).Formula:C17H17BrN2O5Purezza:95.07% - 98%Colore e forma:SolidPeso molecolare:409.23NSC348884
CAS:NSC348884, a nucleophosmin inhibitor, disrupts oligomers, induces apoptosis, and inhibits cancer cell growth (IC50: 1.7-4.0 μM).Formula:C38H40N10Purezza:98.69% - 99.91%Colore e forma:SolidPeso molecolare:636.79Ref: TM-T6909
2mg39,00€5mg58,00€10mg90,00€25mg172,00€50mg280,00€100mg405,00€500mg888,00€1mL*10mM (DMSO)80,00€Notoginsenoside R1
CAS:Notoginsenoside R1 (Sanchinoside R1) has been shown to exhibit antioxidant, antiapoptotic, anti-inflammatory, and immune-stimulatory properties.Formula:C47H80O18Purezza:99.69% - 99.91%Colore e forma:SolidPeso molecolare:933.13Ref: TM-T2961
10mg42,00€25mg71,00€50mg92,00€100mg145,00€200mg219,00€500mg383,00€1mL*10mM (DMSO)43,00€Geranylgeraniol
CAS:Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice.Formula:C20H34OPurezza:99.17% - ≥98%Colore e forma:SolidPeso molecolare:290.48L-Glutamic acid monosodium salt
CAS:L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.Formula:C5H8NO4·NaPurezza:99.93%Colore e forma:White Solid CrystallinePeso molecolare:169.11(Z)-Guggulsterone
CAS:(Z)-Guggulsterone triggers apoptosis in prostate cancer cells and blocks angiogenesis by inhibiting VEGF pathways.Formula:C21H28O2Purezza:98.93% - 99.72%Colore e forma:SolidPeso molecolare:312.45Buparlisib
CAS:Buparlisib (BKM120) is an orally bioavailable specific oral inhibitor of the pan-class I PI3K (IC50s: 52/166/116/nM for p110α, p110β, and p110δ).Formula:C18H21F3N6O2Purezza:95.32% - 98.45%Colore e forma:SolidPeso molecolare:410.39Ref: TM-T1827
5mg59,00€10mg80,00€25mg88,00€50mg109,00€100mg137,00€200mg222,00€500mg403,00€1mL*10mM (DMSO)65,00€CGP 57380
CAS:CGP 57380 (MNK1 Inhibitor) is a potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-likeFormula:C11H9FN6Purezza:98.49%Colore e forma:SolidPeso molecolare:244.23HBX 41108
CAS:HBX 41108: non-competitive, reversible USP7 inhibitor; IC50: 424nM; blocks USP7-p53 deubiquitination; IC50: 0.8μM.Formula:C13H3ClN4OPurezza:95.63%Colore e forma:SolidPeso molecolare:266.64Zoledronic acid disodium tetrahydrate
CAS:Zoledronic Acid, a potent bisphosphonate, inhibits osteoclasts and has anti-cancer effects.Formula:C5H16N2Na2O11P2Colore e forma:SolidPeso molecolare:388.113NS-1619
CAS:NS1619 have cardio-protective effects after ischemia-reperfusion injury.Formula:C15H8F6N2O2Purezza:97.66% - 98%Colore e forma:SolidPeso molecolare:362.23Caffeic Acid Phenethyl Ester
CAS:CAPE, in propolis, blocks NF-kappa B, suppresses p70S6K/Akt pathways, and inhibits PDGF, aiding in cancer protection and immune modulation.Formula:C17H16O4Purezza:99.18% - 99.35%Colore e forma:Less Transparent Liquid Colorless Transparent LiquidPeso molecolare:284.31VR23
CAS:VR23: Potent proteasome inhibitor; IC50: 1 nM trypsin, 50-100 nM chymotrypsin, 3 μM caspase-like.Formula:C19H16ClN5O6SPurezza:98.99% - 99.22%Colore e forma:SolidPeso molecolare:477.88Ziyuglycoside I
CAS:Ziyuglycoside I (Gouguside 7) has anti-inflammatory activity, could be used as an active ingredient for cosmetics.
Formula:C41H66O13Purezza:98.987% - ≥95%Colore e forma:SolidPeso molecolare:766.95Pexidartinib
CAS:Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potentialFormula:C20H15ClF3N5Purezza:98.34% - 99.45%Colore e forma:SolidPeso molecolare:417.81Ref: TM-T2115
5mg46,00€10mg58,00€25mg90,00€50mg114,00€100mg145,00€200mg192,00€500mg333,00€1mL*10mM (DMSO)49,00€Notopterol
CAS:1. Notopterol induces apoptosis and inhibits cell cycle-specific.Formula:C21H22O5Purezza:97.57% - 99.96%Colore e forma:SolidPeso molecolare:354.40PHA-665752
CAS:PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), >50-fold selectivity for c-Met than STKs or RTKs.Formula:C32H34Cl2N4O4SPurezza:97.05% - 98.82%Colore e forma:SolidPeso molecolare:641.61Concanavalin A
CAS:Concanavalin A is a natural product, a phytoalexin. Concanavalin A has antitumor activity and can also induce acute liver injury. Cost effective and quality assured.Formula:C23H32N6O8SPurezza:98%Colore e forma:SolidPeso molecolare:104-112 kDaSR-318
CAS:SR-318 inhibits TNF-α (IC50=283 nM), selectively targets p38 MAPK: IC50 of 5nM (p38α), 32nM (p38β), 6.11μM (p38α/β).Formula:C27H33N5O2Purezza:99.74%Colore e forma:SolidPeso molecolare:459.58Ref: TM-T12997
2mg35,00€5mg55,00€10mg92,00€25mg166,00€50mg259,00€100mg371,00€200mg533,00€1mL*10mM (DMSO)55,00€SCR7 pyrazine
CAS:SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).Formula:C18H12N4OSPurezza:98.72% - 99.85%Colore e forma:SolidPeso molecolare:332.38Ref: TM-T1724
1mg39,00€2mg50,00€5mg79,00€10mg120,00€25mg258,00€50mg408,00€100mg588,00€1mL*10mM (DMSO)79,00€DAPK Substrate Peptide acetate
DAPK Substrate Peptide acetate is a death-associated protein kinase (DAPK, Km = 9 μM) peptide substrate.Formula:C70H115N25O17Purezza:98.12%Colore e forma:SolidPeso molecolare:1578.82Amuvatinib
CAS:Amuvatinib (MP470) is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity.Formula:C23H21N5O3SPurezza:99.38% - >99.99%Colore e forma:SolidPeso molecolare:447.51Chelerythrine chloride
CAS:Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect toFormula:C21H18ClNO4Purezza:95% - 99.19%Colore e forma:Yellow To Orange SolidPeso molecolare:383.83Ref: TM-T3419
2mg34,00€5mg50,00€10mg84,00€25mg145,00€50mg205,00€100mg289,00€200mg432,00€1mL*10mM (DMSO)65,00€Coenzyme Q9
CAS:Coenzyme Q9 (Ubiquinone 9) (CoQ9) is a normal constituent of human plasma.Formula:C54H82O4Purezza:98.2% - 99.47%Colore e forma:SolidPeso molecolare:795.23SSE15206
CAS:SSE15206 is a microtubule polymerization inhibitor that overcomes multidrug resistance.Formula:C19H21N3O3SPurezza:98.81%Colore e forma:SolidPeso molecolare:371.45BMS-1
CAS:BMS-1 is a PD-1/PD-L1 inhibitor and immunomodulator; it targets the CD274 gene product, PD-L1, linked to tumor evasion and higher mortality.
Formula:C29H33NO5Purezza:99.40% - 99.81%Colore e forma:SolidPeso molecolare:475.58Amsilarotene
CAS:Amsilarotene (TAC101) blocks RB phosphorylation, boosts 2 CDK inhibitors, halts cell cycle, and reduces thymidylate synthase and cyclin A levels.Formula:C20H27NO3Si2Purezza:98.05%Colore e forma:SolidPeso molecolare:385.6Ref: TM-T21314
1mg43,00€2mg57,00€5mg96,00€10mg140,00€25mg273,00€50mg393,00€100mg560,00€200mg757,00€1mL*10mM (DMSO)96,00€Oxfenicine
CAS:Oxfenicine, a 4-Hydroxy-L-phenylglycine, inhibits CPT-1, boosts glucose tolerance & insulin sensitivity in obese, insulin-resistant mice.Formula:C8H9NO3Purezza:99.22%Colore e forma:White SolidPeso molecolare:167.16Niraparib tosylate
CAS:Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.
Formula:C19H20N4O·C7H8O3SPurezza:99.34% - 99.87%Colore e forma:SolidPeso molecolare:492.59Tenovin-1
CAS:Tenovin-1 inhibits protein-deacetylating activities of SirT1 and SirT2 and protects against MDM2-mediated p53 degradation, which involves ubiquitination.Formula:C20H23N3O2SPurezza:99.33%Colore e forma:SolidPeso molecolare:369.48Perifosine
CAS:Perifosine (KRX-0401) is an oral-active, alkyl-phosphocholine Akt inhibitor with potential antineoplastic activity.Formula:C25H52NO4PPurezza:99.80 - >99.99%Colore e forma:SolidPeso molecolare:461.66Eprinomectin
CAS:Eprinomectin (MK-397) is an avermectin with anthelmintic and insecticidal activities.Formula:C50H75NO14Purezza:97.84% - ≥95%Colore e forma:SolidPeso molecolare:914.13Cyclovirobuxine D
CAS:Cyclovirobuxine D (Bebuxine) is extracted from Buxus microphylla.Formula:C26H46N2OPurezza:97.78% - 98%Colore e forma:SolidPeso molecolare:402.66Oroxin B
CAS:Oroxin B (Hypocretin-2) has antioxidant activity.Formula:C27H30O15Purezza:98.22% - 99.87%Colore e forma:SolidPeso molecolare:594.52SC66
CAS:SC66 is a AKT inhibitor in HepG2, HA22T/VGH, and PLC/PRF/5 cells (IC50: about 0.75 μg/ml, at 72 h).
Formula:C18H16N2OPurezza:>99.99% - >99.99%Colore e forma:SolidPeso molecolare:276.33BO-264
CAS:BO-264 is a highly potent and orally active inhibitor of transforming acidic coiled-coil 3 (TACC3, IC50 of 188 nM and a Kd of 1.5 nM).Formula:C18H19N5O3Purezza:98.03% - 99.81%Colore e forma:SolidPeso molecolare:353.38SBI-0206965
CAS:SBI-0206965 is a potent, selective and cell-permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for ULK2.
Formula:C21H21BrN4O5Purezza:99.13%Colore e forma:SolidPeso molecolare:489.32Thonningianin A
CAS:Thonningianin A: an anti-cancer compound with antioxidant effects, GST inhibitor, and radical scavenger.Formula:C42H34O21Purezza:98.37% - 99.94%Colore e forma:SolidPeso molecolare:874.71Ref: TM-T3S0218
1mg52,00€2mg67,00€5mg97,00€10mg160,00€25mg263,00€50mg378,00€100mg568,00€1mL*10mM (DMSO)169,00€Capmatinib
CAS:Capmatinib (INCB28060) is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR)with potential antineoplastic activity.Formula:C23H17FN6OPurezza:99.24%Colore e forma:SolidPeso molecolare:412.42Ref: TM-T1963
5mg48,00€10mg63,00€25mg78,00€50mg90,00€100mg124,00€200mg158,00€500mg255,00€1mL*10mM (DMSO)50,00€T-1101 tosylate
CAS:T-1101 tosylate (TAI-95 tosylate) is an inhibitor of Hec1/Nek2, with antitumor activity.Formula:C31H31N5O6S3Purezza:98.1%Colore e forma:SolidPeso molecolare:665.8Ref: TM-T8216
2mg39,00€5mg58,00€10mg93,00€25mg137,00€50mg222,00€100mg371,00€200mg530,00€1mL*10mM (DMSO)86,00€MG-101
CAS:MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins.Formula:C20H37N3O4Purezza:98% - ≥98%Colore e forma:SolidPeso molecolare:383.53Ripretinib
CAS:Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.Formula:C24H21BrFN5O2Purezza:99.07% - 99.62%Colore e forma:SolidPeso molecolare:510.36Ref: TM-T8482
1mg74,00€2mg97,00€5mg165,00€10mg274,00€25mg432,00€50mg692,00€100mg1.121,00€200mg1.539,00€1mL*10mM (DMSO)202,00€Tartrazine
CAS:Tartrazine, a food colorant with potential health risks, may be genotoxic and carcinogenic with long-term use.Formula:C16H9N4Na3O9S2Purezza:98.77% - 98.82%Colore e forma:Yellow Solid PowderPeso molecolare:534.36Tomatine
CAS:Tomatine (lycopersicin) is an antiproliferatve agent of breast adenocarcinoma cells.Formula:C50H83NO21Purezza:98.42% - 99.94%Colore e forma:White To Light YellowPeso molecolare:1034.19Karanjin
CAS:Karanjin, a flavonoid from karanja seeds, boosts GLUT4, AMPK in muscles, and triggers cancer cell apoptosis.Formula:C18H12O4Purezza:99.01%Colore e forma:SolidPeso molecolare:292.29Ref: TM-T2S0820
1mg46,00€5mg96,00€10mg145,00€25mg259,00€50mg385,00€100mg557,00€200mg790,00€1mL*10mM (DMSO)94,00€Asiaticoside
CAS:Asiaticoside, in Centella asiatica, may treat wounds/burns.Formula:C48H78O19Purezza:98% - 99.96%Colore e forma:PowderPeso molecolare:959.12AZ 628
CAS:AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM, 34 nM and 29 nM, also inhibits VEGFR2, DDR2, Lyn, Flt1, FMS, etc.Formula:C27H25N5O2Purezza:99.50%Colore e forma:SolidPeso molecolare:451.52Fipronil
CAS:Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family.Formula:C12H4Cl2F6N4OSPurezza:97.21%Colore e forma:Solid PowderPeso molecolare:437.15A-1331852
CAS:A-1331852 is a potent and selectiveBCL-XL inhibitor and may be useful in the treatment of cancer, immune and autoimmune diseases.Formula:C38H38N6O3SPurezza:98.15% - >99.99%Colore e forma:SolidPeso molecolare:658.81Ref: TM-T6749
1mg51,00€2mg71,00€5mg115,00€10mg177,00€25mg368,00€50mg550,00€100mg787,00€1mL*10mM (DMSO)166,00€BV6
CAS:BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.Formula:C70H96N10O8Purezza:97.46% - 99.82%Colore e forma:SolidPeso molecolare:1205.57Ref: TM-T6428
1mg49,00€2mg64,00€5mg89,00€10mg144,00€25mg285,00€50mg537,00€100mg767,00€1mL*10mM (DMSO)178,00€Bigelovin
CAS:Bigelovin: RXRα agonist, inhibits mTOR via ROS, induces apoptosis/autophagy, anti-tumor sesquiterpene from Inula sp.Formula:C17H20O5Purezza:99.61% - 99.72%Colore e forma:SolidPeso molecolare:304.34Ref: TM-TN6735
1mg96,00€5mg205,00€10mg268,00€25mg465,00€50mg662,00€100mg888,00€1mL*10mM (DMSO)203,00€GSK-2256098 HCl
CAS:GSK-2256098 HCl is a focal adhesion kinase-1 (FAK) inhibitor with potential antiangiogenic and antineoplastic activities.Formula:C20H24Cl2N6O2Colore e forma:SolidPeso molecolare:451.35Licochalcone D
CAS:Licochalcone D may treat melanoma and heart injury, halt cell spread, and reduce inflammation and allergies.Formula:C21H22O5Purezza:99.03% - 99.9%Colore e forma:SolidPeso molecolare:354.4GSK1324726A
CAS:GSK1324726A (I-BET726) is a greatly specific inhibitor of BET family proteins for BRD2(IC50=41 nM), BRD3(IC50=31 nM), and BRD4 (IC50=22 nM).
Formula:C25H23ClN2O3Purezza:98.34% - 99.85%Colore e forma:SolidPeso molecolare:434.91MPI-0479605
CAS:MPI-0479605 is an ATP competitive and selective inhibitor.Formula:C22H29N7OPurezza:97.59% - >99.99%Colore e forma:SolidPeso molecolare:407.51TCS-PIM-1-4a
CAS:SMI-4a, a Pim inhibitor, activates AMPK, halts mTORC1, and kills various myeloid/lymphoid cells (IC50=0.8-40μM).Formula:C11H6F3NO2SPurezza:99.89%Colore e forma:SolidPeso molecolare:273.23Dihydrorotenone
CAS:Dihydrorotenone is a potent mitochondrial inhibitor and probably induces Parkinsonian syndrome.Formula:C23H24O6Purezza:98.98% - 99.58%Colore e forma:SolidPeso molecolare:396.43Ref: TM-TN1586
1mg92,00€5mg250,00€10mg399,00€25mg660,00€50mg888,00€100mg1.198,00€1mL*10mM (DMSO)256,00€C646
CAS:C646, a histone acetyltransferase inhibitor, inhibits p300 (Ki: 400 nM, in a cell-free assay).
Formula:C24H19N3O6Purezza:98% - 99.21%Colore e forma:SolidPeso molecolare:445.42Ref: TM-T2452
2mg48,00€5mg69,00€10mg97,00€25mg195,00€50mg380,00€100mg562,00€500mg1.206,00€1mL*10mM (DMSO)69,00€Glycitein
CAS:1. Gycitein has weak estrogenic activity. 2. Glycitein (Glycetein) inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression.Formula:C16H12O5Purezza:99.23% - 99.94%Colore e forma:White PowderPeso molecolare:284.26Ref: TM-T6S0325
2mg34,00€5mg52,00€10mg65,00€25mg92,00€50mg137,00€100mg193,00€200mg286,00€1mL*10mM (DMSO)52,00€Ispinesib
CAS:Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic
Formula:C30H33ClN4O2Purezza:98% - 99.09%Colore e forma:SolidPeso molecolare:517.06Macitentan
CAS:Macitentan (ACT-064992) is an endothelin receptor antagonist that is used in the therapy of pulmonary arterial hypertension (PAH).Formula:C19H20Br2N6O4SPurezza:98% - >99.99%Colore e forma:SolidPeso molecolare:588.27BDA-366
CAS:BDA-366, a potent Bcl2 antagonist, selectively binds the Bcl2-BH4 domain with high affinity (Ki = 3.3 nM), inducing a conformational change that nullifies itsFormula:C24H29N3O4Purezza:98.61%Colore e forma:SoildPeso molecolare:423.5UNC1215
CAS:UNC1215, a potent MBT antagonist, targets L3MBTL3 with high selectivity (IC50: 40 nM, Kd: 120 nM, 50x versus MBT family).Formula:C32H43N5O2Purezza:98% - 99.04%Colore e forma:SolidPeso molecolare:529.72Difurazon hydrochloride
CAS:Difurazon HCl: a mutagenic antibacterial and growth promoter, used for bacillary dysentery in feed.Formula:C14H13ClN6O6Purezza:98.51%Colore e forma:SolidPeso molecolare:396.74RITA
CAS:RITA (NSC-652287) forms DNA-DNA/protein cross-links without DNA breaks; disrupts p53/Mdm2 like nutlin-3.Formula:C14H12O3S2Purezza:98.49% - 99.55%Colore e forma:SolidPeso molecolare:292.37Ref: TM-T1798
1mg35,00€5mg66,00€10mg96,00€25mg187,00€50mg279,00€100mg420,00€200mg607,00€1mL*10mM (DMSO)89,00€MDK83190
CAS:MDK83190 (Apoptosis Activator 2) is a potent apoptosis activator, induceing caspase-3 activation, PARP cleavage, and DNA fragmentation .Formula:C15H9Cl2NO2Purezza:97.40% - 98%Colore e forma:Orange SolidPeso molecolare:306.14Thapsigargin
CAS:Thapsigargin is a natural product, an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) and an endoplasmic reticulum stress inducer.Formula:C34H50O12Purezza:99.07% - 99.3%Colore e forma:Colourless FilmPeso molecolare:650.75Methoxychlor
CAS:Methoxychlor, an organochlorine pesticide, is thought to be an endocrine disrupter that affects Ca2 homeostasis and cell viability in different cell models.Formula:C16H15Cl3O2Purezza:98.82% - ≥95%Colore e forma:Colorless Crystals (Technical Grey Powder) To The Environment Immediate Steps Should Be Taken To Limit Its Spread To The Environment IfPeso molecolare:345.65RAF265
CAS:RAF265 (CHIR-265) inhibits C-Raf/B-Raf/V600E (IC50: 3-60 nM), blocks VEGFR2 (EC50: 30 nM), in Phase 2 trials.Formula:C24H16F6N6OPurezza:99.56%Colore e forma:SolidPeso molecolare:518.41Ref: TM-T6296
1mg44,00€2mg59,00€5mg93,00€10mg140,00€25mg253,00€50mg413,00€100mg605,00€1mL*10mM (DMSO)94,00€Epieriocalyxin A
CAS:Epieriocalyxin A can suppress Caco-2 colon cancer cell growth. It could be a potential drug for colon cancer therapy in the future.Formula:C20H24O5Purezza:97.00%Colore e forma:SolidPeso molecolare:344.4Helichrysetin
CAS:Helichrysetin shows mild anti-HIV-1 activity and potential as an anticancer agent with cytotoxic effects on A549, MCF-7, Ca Ski, HT-29 cells.Formula:C16H14O5Purezza:96.32% - ≥95%Colore e forma:SolidPeso molecolare:286.28Ref: TM-TN1727
1mg90,00€5mg222,00€10mg331,00€25mg537,00€50mgPrezzo su richiesta1mL*10mM (DMSO)200,00€Flavokawain B
CAS:Flavokawain B inhibits NO and PGE2, causes oxidative stress, and induces apoptosis, with potential for treating prostate cancer.Formula:C17H16O4Purezza:99.97% - >99.99%Colore e forma:SolidPeso molecolare:284.31Quinidine sulfate dihydrate
CAS:Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitor
Formula:C40H54N4O10SPurezza:99.85%Colore e forma:White To Light Yellow Crystal PowdePeso molecolare:782.9Paederosidic acid
CAS:Paederosidic acid shows anti-tumor, anticonvulsant, and sedative properties, may treat epilepsy by modulating brain GABA and glutamate levels.Formula:C18H24O12SPurezza:98% - 99.56%Colore e forma:SolidPeso molecolare:464.445'-Methylthioadenosine
CAS:5'-Methylthioadenosine (Methylthioadenosine) is produced from S-adenosylmethionine and behaves as a powful inhibitory product.Formula:C11H15N5O3SPurezza:99.32% - 99.34%Colore e forma:SolidPeso molecolare:297.33(20S)-Protopanaxatriol
CAS:(20S)-Protopanaxatriol (g-PPT)(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoidFormula:C30H52O4Purezza:95% - 99%Colore e forma:SolidPeso molecolare:476.73Ref: TM-T2810
2mg34,00€5mg50,00€10mg66,00€25mg114,00€50mg178,00€100mg295,00€200mg442,00€1mL*10mM (DMSO)55,00€(Rac)-Idroxioleic acid
CAS:(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a fatty acid amide hydrolase inhibitor with anti-tumor effect.Formula:C18H34O3Purezza:≥98%Colore e forma:SolidPeso molecolare:298.46DL-Buthionine-(S,R)-sulfoximine
CAS:DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.Formula:C8H18N2O3SPurezza:98% - 99.64%Colore e forma:White Fine PowderPeso molecolare:222.31
