Apoptosi

Applications Avasimibe is a selective inhibitor of Cholesterol Acyltransferase 1 and CYP2C9. Avasimibe is known to induce apoptosis of glioma cell lines as a model of glioblastoma.
References Bemlih, S., et al.: Cancer. BIol. Therap., 9, 1025 (2010); Fahmi, O.A., et al.: Drug. Meta. Disp. 38, 1605 (2010);

Applications An Amadori compound having the potential to alter cellular adhesion, inhibit cancer metastasis and induce apoptosis.

Applications L-Selenocystine is a diselenide-bridged amino acid which show chemopreventive activity against tobacco-derived nitrosamine (NNK) induced lung tumors. It causes apoptosis in A375, HepG2 and MCF7 cancer cells by inducing intracellular reactive oxygen species.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Li, L., et al.: J. Biochem. Mol. Toxic., 19, 396 (2005); Chen, T., et al.: Biomed. Pharmacother., 63, 105 (2009);

4-tert-Octylphenol, an endocrine disruptor, hinders neuronal growth and alters behavior in mice.

Applications trans-1-Cinnamylpiperazine is used in the synthesis of bile acid piperazinyl derivatives which display pro-apoptotic properties on carcinoma human cell lines.
References Brossard, D. et al.: Eur. J. Med. Chem., 45, 2912 (2010);

Stability Light Sensitive
Applications Morusin is an inhibitor of human cervical cancer stem cell growth, attenuating NF-kB activity, and initiating apoptosis.
References Wang, L. et al.: Mol. Cell. Biochem., 379, 7 (2013);

Applications Embelin is a natural benzoquinone found in plants of the Myrsinaceae family. Embelin has a wide range of biological activity as it inhibits the growth of bacteria, fungi, protozoa and parasites. Embelin also displays contraceptive and pro-apoptotic properties.
References Stasiuk, M. et al.: Glob. J. Biochem., 2, 262 (2011); Brahmeshwari, G. et al.: Adv. Plant Sci., 24, 467 (2011); Hu, R. et al.: Med. Oncol., 28, 1598 (2011);

Stability Light Sensitive
Applications Pyropheophorbide A Methyl Ester is a chlorophyll (C379815) analog for studies of photosynthesis. Methyl pyropheophorbide a (Pyropheophorbide-a methyl ester), a chlorophyll-a derivative, and is a potent photosensitizer that can be used in photodynamic therapy (PDT) of cancer. Methyl pyropheophorbide a has photodynamic activity and can induce apoptosis and inhibit tumor growth.
References Bensasson, R., et al.: Nature, 290, 329 (1981); Moore, A., et al.: Science, 216, 982 (1982)

Applications Solasodine Hydrochloride enhances the effect of As2O3 in inducing apoptosis in HeLa cell, which is related to its inhibiting telomerase activity in HeLa cells.
References Ai, J., et al.: Chin. J. Endemiol., 30, 279 (2011)

Applications It is a potent inhibitor of protein kinase C (PKC) activity. Bisindolylmaleimide VIII (Bis VIII) has been previously shown to enhance Fas-mediated apoptosis through a protein kinase C-independent mechanism.
References Emery, J., et al.: J. Biol. Chem., 273, 14363 (1998), Wiley, S., et al.: Immunity, 3, 673 (1995), MacFarlane, M., et al.: Biochem. J., 348, 93 (2000),

Applications Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling.
References Cheng, K., et al.: Biochem. J., 330, 353 (1998), Cheng, K., et al.: Cancer Res., 63, 6744 (2003), Bellacosa, A., et al.: Adv. Cancer Res., 94, 29 (2005), Cheng, K., et al.: Biochem. Pharmacol., 70, 1035 (2005), Fang, D., et al.: J. Biol. Chem., 282, 11221 (2007),