Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(1 prodotti)
- Caspasi(153 prodotti)
- FOXO1(2 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(94 prodotti)
- PDK(9 prodotti)
- PERK(26 prodotti)
- Chinasi di serina/treonina(18 prodotti)
- Survivin(14 prodotti)
- TNF(49 prodotti)
- c-RET(60 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 6037 prodotti di "Apoptosi"
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(5Z,2E)-CU-3
CAS:(5Z,2E)-CU-3 is a potent and selective inhibitor of DGKα isozyme with an IC50 value of 0.6 μM and inhibition of DGKα by competing ATP with a Km value of 0.48 mMFormula:C16H12N2O4S3Purezza:99.02%Colore e forma:SolidPeso molecolare:392.47Ref: TM-T10177
1mg46,00€5mg90,00€10mg160,00€25mg340,00€50mg582,00€100mg898,00€500mg1.791,00€1mL*10mM (DMSO)100,00€N1,N11-Diethylnorspermine
CAS:DENSPM: potent anticancer, spurs polyamine breakdown, triggers cytochrome c release and caspase 3, kills GBM via SSAT & H2O2.Formula:C13H32N4Colore e forma:SolidPeso molecolare:244.42Bcl-2-IN-9
CAS:Bcl-2-IN-9: a novel, selective Bcl-2 inhibitor inducing apoptosis in leukemia with an IC50 of 2.9 μM; low cytotoxicity.Formula:C27H31N7O3SColore e forma:SolidPeso molecolare:533.65USP7-IN-4
CAS:USP7-IN-4 is a non-competitive, potent and selective inhibitor of USP7, up-regulates p53 and p21, down-regulates MDM2,anti-proliferativity RS4;11 (leukemia) .Formula:C29H34N6O3Purezza:98.27% - 99.09%Colore e forma:SolidPeso molecolare:514.62Semapimod
CAS:Semapimod is an inhibitor of proinflammatory cytokine production, capable of suppressing TNF-α, IL-1β, and IL-6.Formula:C34H52N18O2Colore e forma:SolidPeso molecolare:744.9ARN5187
CAS:ARN5187, a lysosomal REV-ERB β ligand, inhibits transcription and autophagy, shows efficacy, cytotoxicity, and induces apoptosis.Formula:C24H32FN3OColore e forma:SolidPeso molecolare:397.53DC-CPin711
CAS:DC-CPin711: Potent, selective CBP bromodomain inhibitor, IC50=0.0626 μM; arrests G1 cell cycle, induces apoptosis.Formula:C23H22N4O2Colore e forma:SolidPeso molecolare:386.45STAT3-IN-10
CAS:STAT3-IN-10 (A11) inhibits STAT3; halts tumor growth and triggers apoptosis in cancer cells (IC 50 = 5.18 μM).Formula:C17H13NO5Colore e forma:SolidPeso molecolare:311.29LG190178
CAS:LG190178, a vitamin D receptor (VDR) ligand, is a therapeutic agent used for the treatment of psoriasis, osteoporosis, and secondary hyperparathyroidism.
Formula:C28H42O5Colore e forma:SolidPeso molecolare:458.63CGP74514A
CAS:CGP74514A, a CDK1 inhibitor with anticancer properties, triggers nearly 100% apoptosis in U937 cells within 24 hours.Formula:C19H25Cl2N7Colore e forma:SolidPeso molecolare:422.36Clidanac
CAS:Clidanac is a potent anti-inflammatory drug and is found to uncouple the oxidative phosphorylation.Formula:C16H19ClO2Purezza:98%Colore e forma:SolidPeso molecolare:278.77VS 8
CAS:VS 8: potent oral VEGFR-2 inhibitor, anti-angiogenic, induces cancer cell apoptosis & migration, acts on CSCs.Formula:C26H20F3N3O3Colore e forma:SolidPeso molecolare:479.45PDE4-IN-10
CAS:PDE4-IN-10 (7a), potent PDE4B inhibitor, IC50 7.01μM; selective, stable, TNF-α blocking, non-toxic in vitro.Formula:C18H13NColore e forma:SolidPeso molecolare:243.3YC-137
CAS:YC-137 inhibits BCL-2, triggers apoptosis in Bcl-2-high cells, and blocks its anti-apoptotic function.Formula:C24H21N3O6S2Colore e forma:SolidPeso molecolare:511.57MBM-17S
CAS:MBM-17S, a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 3 nM, effectively inhibits cancer cell proliferation by inducing cell cycle arrest andFormula:C36H40N6O10Purezza:98%Colore e forma:SolidPeso molecolare:716.74Anticancer agent 50
CAS:Anticancer agent 50 targets ABCB1 pump, has cytotoxic effects, alters cyclin D1/p53, and shows promise in T lymphoma research.Formula:C30H32N2O4SeColore e forma:SolidPeso molecolare:563.55Quinate
CAS:Quinate: oral antiarrhythmic, inhibits P450db, blocks K+ channels (IC50 19.9 μM), used in malaria research.Formula:C26H36N2O9Colore e forma:SolidPeso molecolare:520.579AMC-01
CAS:AMC-01 has potential antiviral activity and induces dose- and time-dependent inactivation of eIF2-α via phosphorylation of serine residue 51.Formula:C27H27BrN2O6Purezza:99.95%Colore e forma:SolidPeso molecolare:555.42673-A
CAS:673-A inhibits ALDH1A, depletes ovarian CSCs, induces necroptosis, and reverses chemo resistance.Formula:C15H13NOColore e forma:SolidPeso molecolare:223.27PWT33597 mesylate
CAS:PWT33597 (VDC-597) is an oral PI3K alpha/mTOR dual inhibitor, potentially causing cancer cell death and growth inhibition.Formula:C27H34F2N8O7S2Colore e forma:SolidPeso molecolare:684.7348VEGFR-2-IN-28
CAS:VEGFR-2-IN-28 is a potent inhibitor of VEGFR-2 (IC50: 0.83 μM). VEGFR-2-IN-28 induces apoptosis and exhibits antitumor effects.Formula:C26H17N7O7Colore e forma:SolidPeso molecolare:539.46Lexibulin dihydrochloride
CAS:Lexibulin 2HCl inhibits tubulin polymerization (IC50: 10-100 nM) and shows potent anti-cancer cytotoxicity and vascular disruption in vitro/vivo.Formula:C24H32Cl2N6O2Purezza:98%Colore e forma:SolidPeso molecolare:507.46Anticancer agent 59
Anticancer agent 59 suppresses various cancers, notably A549 at IC50 of 0.2 μM, induces apoptosis and disrupts mitochondria in mice.Formula:C42H59NO6Colore e forma:SolidPeso molecolare:673.92PI3K/AKT-IN-2
CAS:PI3K/AKT-IN-2 inhibits PI3K/AKT, EMT, induces apoptosis, and blocks tubulin polymerization.Formula:C32H27BrO10Colore e forma:SolidPeso molecolare:651.45IQDMA
CAS:IQDMA is an inhibitor of the transcription factor STAT5.Formula:C19H20N4Colore e forma:SolidPeso molecolare:304.39MPT0B392
CAS:MPT0B392 is an orally active quinoline derivative, induces c-Jun N-terminal kinase (JNK) activation.Formula:C19H20N2O6SColore e forma:SolidPeso molecolare:404.44iMAC2
CAS:iMAC2, a potent MAC (Membrane Attack Complex) inhibitor, exhibits an IC50 of 28 nM and an LD50 of 15,000 nM, demonstrating significant efficacy in inhibitingFormula:C19H20Br2FN3Colore e forma:SolidPeso molecolare:469.192,5-Dihydroxybiphenyl
CAS:2,5-Dihydroxybiphenyl: a small molecule that induces trichothiodystrophy A protein dimerization, modulating TFIIH activity.
Formula:C12H10O2Purezza:99.66%Colore e forma:White To Grey-Brownish PowderPeso molecolare:186.21Verrucarin J
CAS:Verrucarin J, a Myrothecium fungus metabolite, triggers apoptosis in some cancer cells and fights Candida, Mucor, and JUNV (IC50: 1.2 ng/mL).Formula:C27H32O8Colore e forma:SolidPeso molecolare:484.54Prexasertib mesylate
CAS:Prexasertib (LY2606368), a Chk1/2 inhibitor, enhances therapy in acute lymphoblastic leukemia, causing DNA damage and antitumor effects.Formula:C19H23N7O5SPurezza:98%Colore e forma:SolidPeso molecolare:461.49Zoledronate disodium
CAS:Zoledronate disodium inhibits osteoclasts, lowers bone turnover, stabilizes matrix, and has anti-tumor effects in osteosarcoma.Formula:C5H8N2Na2O7P2Colore e forma:SolidPeso molecolare:316.0531GRI977143
CAS:GRI977143: selective LPA2 agonist (EC50=3.3μM), blocks caspases 3/7/8/9, limits DNA fragmentation.Formula:C22H17NO4SPurezza:99.08%Colore e forma:SolidPeso molecolare:391.44Antitumor agent-81
CAS:Antitumor agent-81, a P62-RNF168 agonist, reduces H2A ubiquitination, hinders DNA repair, and inhibits tumor growth.Formula:C19H19N7O3Colore e forma:SolidPeso molecolare:393.4RET-IN-16
CAS:RET-IN-16: Selective RET inhibitor, IC50s 3.98-15.05 nM for various RET mutations; anticancer properties.Formula:C31H29F3N8O2Colore e forma:SolidPeso molecolare:602.61Atopaxar Hydrobromide
CAS:Atopaxar, a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.Formula:C29H39BrFN3O5Purezza:98%Colore e forma:SolidPeso molecolare:608.54Tubulin inhibitor 30
CAS:Tubulin Inhibitor 30, exhibiting an IC50 value of 0.52 μM, functions as an inhibitor of tubulin assembly. Additionally, it can induce ferroptosis.Formula:C22H19N3O5Colore e forma:SolidPeso molecolare:405.4SEC
CAS:SEC triggers ANXA7 GTPase via AMPK/mTORC1/STAT3, causing ITGB4-driven apoptosis in ITGB4-high cancer cells.Formula:C22H23ClN2O5Colore e forma:SolidPeso molecolare:430.88FW1256
CAS:FW1256: phenyl analog, slow H2S donor, inhibits NF-κB, induces apoptosis, anti-inflammatory, potential cancer/cardio treatment.Formula:C12H10NOPSColore e forma:SolidPeso molecolare:247.25FD223
CAS:FD223, a PI3Kδ inhibitor, is highly potent (IC50=1 nM) and selective, limiting AML cell growth by causing G1 arrest.Formula:C17H12ClN5O2SColore e forma:SolidPeso molecolare:385.832-chloro Palmitic Acid
CAS:2-chloro Palmitic acid triggers NETosis, elevates COX-2, adhesion molecules in HCAECs, and induces apoptosis and caspase-3 in THP-1 cells/monocytes.Formula:C16H31ClO2Colore e forma:SolidPeso molecolare:290.87S116836
CAS:S116836 is a tyrosine kinase inhibitor.Formula:C27H21F3N6OPurezza:98%Colore e forma:SolidPeso molecolare:502.49CAY10773
CAS:CAY10773, a sorafenib derivative, inhibits cancer cells over non-cancerous ones and induces apoptosis or ferroptosis in T24 cells.Formula:C22H17Cl2N5OColore e forma:SolidPeso molecolare:438.317DG
CAS:7DG is a selective inhibitor of protein kinase R (PKR).Formula:C26H30O5Colore e forma:SolidPeso molecolare:422.51p53 Activator 3
CAS:Potent p53 activator, SC150 <0.05 mM, restores mutant p53 DNA binding, exhibits anti-tumor properties.Formula:C30H37F3N4O4SColore e forma:SolidPeso molecolare:606.7ENMD-1068 HCl
CAS:ENMD-1068 HCl (ENMD 1068) is a PAR-2 antagonist. ENMD-1068 HCl inhibits the development of endometriosis in a mouse model.Formula:C15H29N3O2Purezza:99.91%Colore e forma:SolidPeso molecolare:283.41BIBU-1361 dihydrochloride
CAS:BIBU-1361 dihydrochloride inhibits EGFR kinase, blocking MAPKK/MAPK activation.Formula:C22H29Cl3FN7Colore e forma:SolidPeso molecolare:516.87PD1-PDL1-IN 1
CAS:PD1-PDL1-IN 1 is a potent inhibitor of programmed cell death 1 (PD-1),and used as immune modulator.Formula:C14H23N7O6Purezza:98%Colore e forma:SolidPeso molecolare:385.38FAK-IN-5
CAS:FAK-IN-5 is a FAK signaling inhibitor that induces apoptosis and autophagy.Formula:C29H29ClF3N3O4Colore e forma:SolidPeso molecolare:576.01SS28
CAS:SS28 inhibits tubulin polymerization to cause cell cycle arrest at G2/M phase.Formula:C18H20O3Purezza:98%Colore e forma:SolidPeso molecolare:284.35MMP-9-IN-5
CAS:MMP-9-IN-5: MMP-9 and AKT inhibitor (IC50: 4.49 nM and 1.34 nM), induces apoptosis for cancer research.Formula:C27H20IN3O4Colore e forma:SolidPeso molecolare:577.37ANO1-IN-3
CAS:ANO1-IN-3 (Compound 3n) can induces apoptosis that is a potent and selective inhibitor of ANO1 with an IC 50 of 1.23 μM [1].Formula:C20H17NO3Colore e forma:SolidPeso molecolare:319.35Ormeloxifene
CAS:estrogen receptor modulatorFormula:C30H35NO3Purezza:98%Colore e forma:SolidPeso molecolare:457.6Caspase-3-IN-1
CAS:Caspase-3-IN-1 is a potent inhibitor of Caspase-3 (IC50: 14.5 nM).Formula:C26H25N3O6SColore e forma:SolidPeso molecolare:507.56KS106
CAS:KS106 inhibits ALDH (1A1: 334 nM, 2: 2137 nM, 3A1: 360 nM), has anti-cancer properties, raises ROS, and promotes aldehyde build-up.Formula:C18H15BrF3N3O2SPurezza:99.31%Colore e forma:SolidPeso molecolare:474.3Sparfosic Acid
CAS:Sparfosic Acid (Acide sparfosique) is an aspartate carbamoyltransferase inhibitor with antitumor activity and can be used to study advanced renal cell carcinomaFormula:C6H10NO8PPurezza:98.89%Colore e forma:SolidPeso molecolare:255.12SCAL-255
CAS:SCAL-255 is a mitochondrial complex I (CI) inhibitor, exhibiting potent inhibition with an IC50 of 1.14 μM.Formula:C27H28F3N5O3Purezza:98%Colore e forma:SolidPeso molecolare:527.54Talaporfin free acid
CAS:Talaporfin, an effective tumor localizer, can produce the selective degradation of tumor tissue following light exposure.Formula:C38H41N5O9Colore e forma:SolidPeso molecolare:711.76Epinephrine bitartrate
CAS:L-Epinephrine Bitartrate is alpha- and beta-adrenergic receptor stimulator.Formula:C13H19NO9Purezza:99.07% - 99.94%Colore e forma:White SolidPeso molecolare:333.3Rohinitib
CAS:Rohinitib, an eIF4A inhibitor, triggers apoptosis in AML cells and lessens tumor load in models.Formula:C29H31NO8Colore e forma:SolidPeso molecolare:521.56JMX0293
JMX0293, a salicylamide derivative, inhibits STAT3, inducing MDA-MB-231 cell apoptosis with IC50=3.38μM, while sparing MCF-10A (IC50>60μM).Formula:C25H30Cl2N4O7Colore e forma:SolidPeso molecolare:569.43Undecylprodigiosin
CAS:Undecylprodigiosin is a classical cytotoxic immunosuppressant, suppressing immune functions. It also inhibits DNA synthesis.Formula:C25H35N3OColore e forma:SolidPeso molecolare:393.56Fenoldopam hydrochloride
CAS:Fenoldopam HCl: D1 dopamine receptor agonist, vasodilator, doesn't cross blood-brain barrier, α2-adrenoceptor antagonist.Formula:C16H17Cl2NO3Colore e forma:SolidPeso molecolare:342.22Metoprolol HCl
CAS:Metoprolol: a β1 blocker for high blood pressure, chest pain, fast heart rate, post-heart attack care, and migraine prevention.Formula:C15H26ClNO3Colore e forma:SolidPeso molecolare:303.827PD-1/PD-L1-IN-28
CAS:PD-1/PD-L1-IN-28, an inhibitor of the PD-1/PD-L1 signaling pathway (IC 50 = 0.744 µM), demonstrates promising research potential in tumor immunity.Formula:C24H24N4O2Colore e forma:SolidPeso molecolare:400.47NKP-1339
CAS:NKP-1339 (IT-139) induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway.Formula:C14H12Cl4N4NaRuPurezza:98%Colore e forma:SolidPeso molecolare:502.14PD-1/PD-L1-IN-20
CAS:PD-1/PD-L1-IN-20 is a small molecule inhibitor of PD-1/PD-L1 protein-protein interaction.Formula:C30H26BrClN2O3Colore e forma:SolidPeso molecolare:577.9SID 3712249
CAS:SID 3712249 is an inhibitor of the biogenesis of microRNA-544 (miR-544).Formula:C17H21N7Purezza:98%Colore e forma:SolidPeso molecolare:323.4SKI-I
CAS:SKI-I: Human sphingosine kinase inhibitor, IC50 1.2μM; hERK2 inhibitor, IC50 11μM; promotes tumor cell apoptosis.Formula:C25H18N4O2Colore e forma:SolidPeso molecolare:406.44HDACs/mTOR Inhibitor 1
CAS:HDACs/mTOR Inhibitor 1 is a dual HDACs and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies (IC50s: 0.19 nM, 1.8 nM,Formula:C28H38N8O5Colore e forma:SolidPeso molecolare:566.65Ro 31-7837
CAS:Ro 31-7837 is an opener of potassium channel.Formula:C17H16N2O2Colore e forma:SolidPeso molecolare:280.32EAPB 02303
CAS:EAPB 02303, a microtubule inhibitor, induces mitotic arrest, spindle impairment, apoptosis, and has antitumor effects, enhancing Paclitaxel.Formula:C17H14N4O2Colore e forma:SolidPeso molecolare:306.32Anti-inflammatory agent 17
CAS:Compound 17: Orally active, potent IL-6 & TNF-α inhibitor; not cytotoxic; promising for ALI research.Formula:C20H23NO5Colore e forma:SolidPeso molecolare:357.4Cl-Necrostatin-1
CAS:Cl-Necrostatin-1 is an inhibitor of receptor-interacting protein kinase. It inhibits RIPK1 activity.Formula:C13H12ClN3OSColore e forma:SolidPeso molecolare:293.77HS-438
CAS:HS-438 inhibits imatinib-resistant BCR-ABL T315I mutation in chronic myeloid leukemia.Formula:C17H17N3O3SColore e forma:SolidPeso molecolare:343.4CT1-3
CAS:CT1-3 is a potent anti-cancer compound targeting JNK/Bcl-2 pathways, blocking EMT in HCCs, and is non-toxic to liver/kidneys in mice.Formula:C25H29NO3S2Colore e forma:SolidPeso molecolare:455.63ZK-304709 HCl
CAS:ZK-304709 is an oral multitarget tumor growth inhibitor with activity against cell-cycle progression and angiogenesis.Formula:C22H29ClN6O2Colore e forma:SolidPeso molecolare:444.96Flonoltinib
CAS:Flonoltinib (JAK2/FLT3-IN-1) is an orally active and efficient JAK2/FLT3 inhibitor with anti-cancer properties.Formula:C25H34FN7OPurezza:99.52%Colore e forma:SolidPeso molecolare:467.58ARN5187 trihydrochloride
CAS:ARN5187 trihydrochloride: a REV-ERBβ inhibitor that blocks transcription, autophagy, and induces apoptosis with lysosomal cytotoxicity.Formula:C24H35Cl3FN3OColore e forma:SolidPeso molecolare:506.912LWG-301
LWG-301, a GLS1 allosteric inhibitor, IC50 7 nM, impedes glutamine metabolism and prompts apoptosis; shows antitumor effects.Formula:C28H38N8O3SColore e forma:SolidPeso molecolare:566.72SCAL-266
CAS:SCAL-266, a potent inhibitor of mitochondrial complex I (CI), exhibits an IC50 of 0.83 μM.Formula:C27H28F3N5O2Purezza:98%Colore e forma:SolidPeso molecolare:511.54RSH-7
CAS:RSH-7 is a potent dual inhibitor of BTK and FLT3, with IC50s of 47 and 12 nM, respectively.RSH-7 has antiproliferative and antitumor activities, inducingFormula:C22H25FN8OPurezza:99.43%Colore e forma:SolidPeso molecolare:436.49VU0424465
CAS:VU0424465 is a mGlu5-selective allosteric agonist.Formula:C19H19FN2O2Colore e forma:SolidPeso molecolare:326.36ACA-28
CAS:ACA-28 is an ERK MAPK signalling modulator that induces apoptosis in melanoma cells by overexpressing ERK.Formula:C17H16O6Purezza:98.73%Colore e forma:SolidPeso molecolare:316.31Ref: TM-T60821
1mg101,00€5mg241,00€10mg382,00€25mg754,00€50mg1.238,00€100mg1.839,00€200mg2.489,00€1mL*10mM (DMSO)265,00€CDK1/2/4-IN-1
CAS:CDK1/2/4-IN-1 inhibits CDKs (IC50: CDK1-1.47μM; CDK2-0.78μM; CDK4-0.87μM) and is useful in cancer studies, affecting apoptosis and the cell cycle.Formula:C15H16N2O2SColore e forma:SolidPeso molecolare:288.36JS-K
CAS:JS-K is a Nitric oxide donor. It has antiproliferative activity.Formula:C13H16N6O8Colore e forma:SolidPeso molecolare:384.3Adapalene sodium salt
CAS:Adapalene (CD 271; Differin) sodium salt is a synthetic retinoid and a Retinoic acid receptor agonist.Formula:C28H28NaO3Purezza:98%Colore e forma:SolidPeso molecolare:435.519CAY10406
CAS:CAY10406, a trifluoromethyl isatin sulfonamide, selectively targets and inhibits caspase-3 and -7, key in apoptosis, with no data on its inhibition potency.Formula:C27H23F3N2O5SColore e forma:SolidPeso molecolare:544.54EGFR-IN-56
CAS:EGFR-IN-56 (13a) inhibits EGFR, EGFRT790M (IC50: 541.7nM), EGFRT790M/L858R (IC50: 132.1nM), blocks G2/M phase, and triggers apoptosis.Formula:C23H22N4O3SColore e forma:SolidPeso molecolare:434.51GL-V9
CAS:GL-V9 is an AMPK activator, protecting against colitis-associated colorectal cancer by limiting NLRP3 inflammasome through autophagy.Formula:C24H27NO5Colore e forma:SolidPeso molecolare:409.47AZD 1152 (hydrochloride)
CAS:AZD 1152, an oral prodrug, becomes AZD 1152-HQPA in plasma, selectively inhibits Aurora kinase B (IC50=0.36 nM), and blocks tumor growth.Formula:C26H33Cl2FN7O6PColore e forma:SolidPeso molecolare:660.47pan-HER-IN-2
CAS:pan-HER-IN-2 (Compound C6) is an orally active, reversible, broad-spectrum HER inhibitor that acts on EGFR (IC50: 0.72 nM), HER4 (IC50: 2.0 nM), EGFRT790M (IC50Formula:C19H15BrClN5OColore e forma:SolidPeso molecolare:444.71VEGFR-2/BRAF-IN-2
VEGFR-2/BRAF-IN-2 inhibits VEGFR-2, BRAF V600E, BRAF WT (IC50: 0.111/0.089/0.071 µM); induces G1 arrest and apoptosis.Formula:C26H21ClF3N5O3S2Colore e forma:SolidPeso molecolare:608.05Anticancer agent 55
CAS:Potent anticancer agent inhibits cell growth, migration, induces apoptosis; promising for prostate, breast cancer studies.Formula:C28H21Br2FN2O2Colore e forma:SolidPeso molecolare:596.294Nevanimibe
CAS:Nevanimibe is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).Formula:C27H39N3OPurezza:98%Colore e forma:SolidPeso molecolare:421.62ICG-001
CAS:ICG001 is a β-catenin/TCF-mediated transcription inhibitor that selectively blocks β-catenin/CBP interaction.Cost-effective and quality-assured.Formula:C33H32N4O4Purezza:99.55% - 99.62%Colore e forma:SolidPeso molecolare:548.63Ref: TM-T6113
1mg35,00€5mg70,00€10mg106,00€25mg207,00€50mg360,00€100mg558,00€500mg1.198,00€1mL*10mM (DMSO)86,00€PARP1-IN-10
CAS:PARP1-IN-10 (12c) is a potent, non-toxic PARP1 inhibitor with a 50.62 nM IC50, enhancing TMZ effects and causing G2/M arrest and apoptosis.Formula:C20H23N3O5Colore e forma:SolidPeso molecolare:385.4115(S)-HpETE
CAS:15(S)-HpETE is a product of arachidonic acid formed in the 15-lipoxygenase pathway and inhibits angiogenesis.Formula:C20H32O4Colore e forma:SolidPeso molecolare:336.47HDAC6-IN-4
CAS:HDAC6-IN-4 (C10), an oral, selective, potent HDAC6 inhibitor with low toxicity, IC50: 23 nM, promotes apoptosis and strong anti-tumor action.Formula:C30H38N2O5Colore e forma:SolidPeso molecolare:506.63ABT-100
CAS:ABT-100 is a potent, highly selective, and orally active farnesyl transferase inhibitor with broad-spectrum antitumor activity.Formula:C27H19F3N4O3Purezza:98%Colore e forma:SolidPeso molecolare:504.46
