Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(1 prodotti)
- Caspasi(154 prodotti)
- FOXO1(2 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(109 prodotti)
- PDK(9 prodotti)
- PERK(26 prodotti)
- Chinasi di serina/treonina(18 prodotti)
- Survivin(14 prodotti)
- TNF(64 prodotti)
- c-RET(61 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 6100 prodotti di "Apoptosi"
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Dipin
CAS:Dipin is an Antineoplastic.Formula:C12H24N6O2P2Purezza:98%Colore e forma:SolidPeso molecolare:346.31BMH-9
CAS:BMH-9 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.Formula:C19H27N3O2Colore e forma:SolidPeso molecolare:329.44PDE5-IN-3
CAS:PDE5-IN-3: Inhibits PDE5 (1.57 nM), EGFR (5.827 μM), Wnt pathway (1286.96 ng/mL), induces apoptosis, and has antitumor effects.Formula:C21H14BrN5O2Colore e forma:SolidPeso molecolare:448.27IM-54
CAS:IM-54 is a cell-permeable, effective, and selective necrosis inhibitor.Formula:C19H23N3O2Purezza:99.24%Colore e forma:SolidPeso molecolare:325.4Ref: TM-T24160
1mg49,00€5mg104,00€10mg164,00€25mg281,00€50mg404,00€100mg567,00€1mL*10mM (DMSO)115,00€NSC260594
CAS:NSC260594 is a chemical compound that promotes apoptosis by binding to the shallow groove of the Mcl-1 protein and suppressing its expression through down-Formula:C29H24N6O3Colore e forma:SolidPeso molecolare:504.54Topoisomerase I inhibitor 2
CAS:ZML-8 selectively inhibits Top1, blocks G2/M phase, causes DNA damage, and induces apoptosis with anti-tumor properties.Formula:C18H15NO3Colore e forma:SolidPeso molecolare:293.32Xanthine oxidase-IN-6
Xanthine oxidase-IN-6: potent oral mixed-type XOD inhibitor, IC50 1.37 µM, anti-hyperuricemia, renal protection.Formula:C29H34N2O15Colore e forma:SolidPeso molecolare:650.58Prinomastat hydrochloride
CAS:Prinomastat HCl, an oral MMP (1, 3, 9) inhibitor, IC50s: 79, 6.3, 5.0 nM, shows antitumor activity.
Formula:C18H22ClN3O5S2Purezza:98%Colore e forma:SolidPeso molecolare:459.97PI3Kα-IN-6
CAS:PI3Kα-IN-6 (Compound 5b) is a PI3Kα inhibitor that exhibits anticancer effects without toxicity to normal cells.Formula:C16H15IN2OSColore e forma:SolidPeso molecolare:410.27Oxythiamine chloride HCl
CAS:Oxythiamine chloride is a thiamine antagonist and anticancer agent that inhibits transketolase, affecting RNA/DNA synthesis and inducing apoptosis.Formula:C12H17Cl2N3O2SColore e forma:SolidPeso molecolare:338.25Esuberaprost Sodium
CAS:Famitinib (SHR1020), an oral drug, inhibits c-kit, VEGFR-2, and PDGFRβ (IC50: 2.3/4.7/6.6 nM) and triggers apoptosis in gastric cancer.Formula:C23H27FN4O2Colore e forma:SolidPeso molecolare:410.48TNF-α-IN-1
CAS:TNF-α-IN-1 is a TNF-α inhibitor.Formula:C16H14ClN3O5Purezza:98.82%Colore e forma:SolidPeso molecolare:363.75Ref: TM-T13175
1mg56,00€5mg120,00€10mg178,00€25mg330,00€50mg505,00€100mg713,00€1mL*10mM (DMSO)203,00€Vin-C01
CAS:Vin-C01, a potent protector of pancreatic β-cells (EC50=0.22μM), aids in type 2 diabetes research by preventing STZ-induced β-cell apoptosis.Formula:C20H24N2OColore e forma:SolidPeso molecolare:308.42Epofolate
CAS:Epofolate: folate receptor-targeted antimitotic, delivers epothilone to cancer cells, inhibits mitosis, may halt tumor growth. Check clinical trials.Formula:C67H92N16O22S3Colore e forma:SolidPeso molecolare:1569.74ZDLD13
CAS:ZDLD13, a β-carboline, inhibits CDK4/CycD3, halts HCT116 tumor growth, and induces apoptosis with IC50=0.38μM.Formula:C18H14N4OColore e forma:SolidPeso molecolare:302.33L 741742 (free base)
CAS:L 741742 is an effective and highly selective antagonist of the D4 dopamine receptor (Ki: 1700, 770, and 3.5 nM at cloned human D2, D3, and D4 receptors).Formula:C23H25ClN2OPurezza:98%Colore e forma:SolidPeso molecolare:380.91MI-1061
CAS:MI-1061 is a orally bioavailable inhibitor of MDM2 (MDM2-p53 interaction) (IC50=4.4 nM).Formula:C30H26Cl2FN3O4Colore e forma:SolidPeso molecolare:582.45NKP-1339
CAS:NKP-1339 (IT-139) induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway.Formula:C14H12Cl4N4NaRuPurezza:98%Colore e forma:SolidPeso molecolare:502.14ALC67
CAS:ALC67, a novel 3-propionyl thiazolidine-4-carboxylic acid ethyl ester, activates caspase-9, showing potent anticancer properties.Formula:C15H15NO3SPurezza:98%Colore e forma:SolidPeso molecolare:289.35NSC-741909
CAS:NSC-741909 is an anticancer agent that acts by suppressing the growth of several cell lines.Formula:C16H14ClNOPurezza:98%Colore e forma:SolidPeso molecolare:271.74Topoisomerase I inhibitor 5
CAS:Topoisomerase I inhibitor 5 halts DNA replication, induces MCF-7 cell apoptosis, and overcomes drug resistance. IC50 value is noted.Formula:C24H24N2O2Colore e forma:SolidPeso molecolare:372.46BJE6-106
CAS:BJE6-106, Selective PKCδ inhibitor (IC50=0.05 μM), induces caspase-dependent apoptosis, activates JNK/H2AX, for NRAS-mutated melanoma.Formula:C26H23NO2Colore e forma:SolidPeso molecolare:381.47Glucocorticoid receptor modulator 1
CAS:Glucocorticoid receptor modulator 1 is a orally NF-κB and AP-1 inhibitor, inflammatory factors IL-6, IL-1β, TNF-α, and MMP-13, alleviating skin inflammation.Formula:C24H23ClN2O4SPurezza:99.79%Colore e forma:SolidPeso molecolare:470.97Ref: TM-T72102
1mg64,00€5mg137,00€10mg210,00€25mg424,00€50mg615,00€100mg847,00€1mL*10mM (DMSO)140,00€SDZ 224-015
CAS:SDZ 224-015 is an inhibitor of interleukin-1β (IL-1β) converting enzyme and caspase-1 with anti-COVID-19 and anti-inflammatory activity.Formula:C30H35Cl2N3O9Purezza:95.49% - 95.49%Colore e forma:SolidPeso molecolare:652.52NVS-CECR2-1
CAS:NVS-CECR2-1 is a CECR2 inhibitor with anti-tumor activity that inhibits chromatin binding of the CECR2 BRD.Formula:C27H37N5O2SPurezza:98.68%Colore e forma:SolidPeso molecolare:495.68Propiomazine
CAS:Propiomazine is an orally active antihistamine compound with sedative properties, useful for controlling insomnia in neurological disorders.Formula:C20H24N2OSPurezza:98.5%Colore e forma:SolidPeso molecolare:340.48CMLD012073
CAS:CMLD012073: Potent eIF4A inhibitor, halts eukaryotic translation; IC50 10 nM in NIH/3T3 cells.Formula:C30H30N2O7Purezza:98%Colore e forma:SolidPeso molecolare:530.57ARP 101
CAS:ARP 101 is a selective matrix metalloproteinase-2 (MMP-2) inhibitor with anticancer activity.Formula:C20H26N2O5SPurezza:98.26%Colore e forma:SolidPeso molecolare:406.5Ref: TM-T22034
1mg94,00€5mg221,00€10mg356,00€25mg737,00€50mg1.125,00€100mg1.521,00€200mg2.052,00€1mL*10mM (DMSO)241,00€CDK1/Cyc B-IN-1
CAS:CDK1/Cyc B-IN-1: Potent CDK1/Cyc B inhibitor, IC50 97 nM, induces apoptosis, arrests G2/M cycle, halts cancer growth.Formula:C14H12ClN3O2S2Colore e forma:SolidPeso molecolare:353.85CSRM617
CAS:CSRM617: selective ONECUT2 inhibitor, Kd 7.43 uM, binds OC2-HOX, induces apoptosis, tolerable in mouse prostate cancer model.Formula:C10H13N3O5Purezza:98%Colore e forma:SolidPeso molecolare:255.23HSP90-IN-13
CAS:HSP90-IN-13 (5k): potent HSP90 inhibitor, IC50 25.07 nM, targets EGFR/VEGFR-2/Topo-2, blocks MCF-7 G2/M cycle, induces apoptosis.Formula:C26H21N5O3SColore e forma:SolidPeso molecolare:483.54HJC0416
CAS:HJC0416 is a potent orally bioavailable signal transducer and activator of transcription 3 inhibitor.Formula:C18H17ClN2O4SPurezza:98%Colore e forma:SolidPeso molecolare:392.86RIPK3-IN-2
CAS:RIPK3-IN-2 is a RIP3 inhibitor that can be used in studies of diseases caused by or associated with activated necrotic pathways.Formula:C21H16ClN3O2S2Colore e forma:SolidPeso molecolare:441.95Tezacitabine
CAS:Tezacitabine, a nucleoside analogue, inhibits ribonucleotide reductase, disrupts DNA replication, and induces apoptosis in tumor cells.Formula:C10H12FN3O4Colore e forma:SolidPeso molecolare:257.22VRT-043198
CAS:VRT-043198, a VX-765 metabolite, is a potent ICE/caspase-1 inhibitor, crossing the blood-brain barrier with K i of 0.8/0.6 nM.Formula:C22H29ClN4O6Colore e forma:SolidPeso molecolare:480.94GRI977143
CAS:GRI977143: selective LPA2 agonist (EC50=3.3μM), blocks caspases 3/7/8/9, limits DNA fragmentation.Formula:C22H17NO4SPurezza:99.08%Colore e forma:SolidPeso molecolare:391.44TJ08
CAS:TJ08 has anticancer properties and can effectively induce G1/S phase blockade while promoting apoptosis in a variety of cancer cells.Formula:C22H16FN3O4Purezza:99.89%Colore e forma:SolidPeso molecolare:405.38PD-1/PD-L1-IN 6
CAS:Compound A13 inhibits PD-1/PD-L1, enhances interferon-γ, lacks toxicity, and boosts immune response in co-culture models. IC50=132.8 nM.Formula:C25H26N2O3Colore e forma:SolidPeso molecolare:402.49EP12
CAS:EP12, a c-Myc inhibitor and G4 stabilizer, induces apoptosis and DNA damage in multiple myeloma cells while obstructing P65/P50 nuclear translocation byFormula:C26H22FN3O2Purezza:98%Colore e forma:SolidPeso molecolare:427.47Anticancer agent 164
CAS:CML-IN-1, also known as compound 7 and compound 4, is a potent anticancer agent that demonstrates a strong induced-apoptosis effect in the human chronic myeloidFormula:C21H23F3N8O2S2Purezza:98%Colore e forma:SolidPeso molecolare:540.58Telomerase-IN-4
CAS:Telomerase-IN-4 is a potent inhibitor of telomerase with antiproliferative properties and induces apoptosis [1].Formula:C21H18N4OS2Purezza:98%Colore e forma:SolidPeso molecolare:406.52Ac-IETD-CHO
CAS:Ac-IETD-CHO is a potent, reversible inhibitor of granzyme B and caspase 8, which also impedes Fas-mediated apoptosis, hemorrhagic conditions, and liver failure.Formula:C21H34N4O10Purezza:98%Colore e forma:SolidPeso molecolare:502.52CMLD012072
CAS:CMLD012072 is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor with potent anti-neoplastic activity. It can induce RNA clamping of eIF4A1 and eIF4A2.Formula:C32H32N2O7Purezza:98%Colore e forma:SolidPeso molecolare:556.61Antiproliferative agent-32
CAS:Antiproliferative agent-32 (Compound 1c) impedes phosphorylation within the PI3K/Akt/mTOR signaling pathway, restrains proliferation of Huh7 and SK-Hep-1 cellsFormula:C19H15NO2Purezza:98%Colore e forma:SolidPeso molecolare:289.33Antitumor agent-115
CAS:Antitumor agent-115 (SS-12) is a potent anti-tumor compound, exhibiting an IC50 range of 0.34 μM-24.14 μM against the 4T1 mouse breast cancer cell line.Formula:C19H38ClNO2Purezza:98%Colore e forma:SolidPeso molecolare:347.96AG6033
CAS:AG6033, a novel CRBN modulator, degrades GSPT1/IKZF1 and inhibits various tumors.Formula:C30H23N5O4Colore e forma:SolidPeso molecolare:517.53HDAC-IN-31
CAS:HDAC-IN-31: Oral HDAC inhibitor; targets HDAC1, 2, 3; weak on HDAC8; potential in fighting lymphoma.Formula:C25H24N4O2Colore e forma:SolidPeso molecolare:412.48CPI-7c
CAS:CPI-7c inhibits MDM2-p53 interaction and promotes MDM2 degradation.Formula:C22H18N2O3Purezza:98%Colore e forma:SolidPeso molecolare:358.39Bisindolylmaleimide VIII
CAS:Bisindolylmaleimide VIII (Ro-31-7549) is a selective and highly potent protein kinase C (PKC) inhibitor.
Formula:C24H22N4O2Purezza:97% - 98.01%Colore e forma:SolidPeso molecolare:398.46RIPK1-IN-15
CAS:RIPK1-IN-15 (Compound 2.5) is a potent RIPK1 inhibitor that has the potential in neurodegenerative, autoimmune, and inflammatory diseases research [1].Formula:C19H19N3O2Colore e forma:SolidPeso molecolare:321.37ABT-100
CAS:ABT-100 is a potent, highly selective, and orally active farnesyl transferase inhibitor with broad-spectrum antitumor activity.Formula:C27H19F3N4O3Purezza:98%Colore e forma:SolidPeso molecolare:504.46Prexasertib mesylate
CAS:Prexasertib (LY2606368), a Chk1/2 inhibitor, enhances therapy in acute lymphoblastic leukemia, causing DNA damage and antitumor effects.Formula:C19H23N7O5SPurezza:98%Colore e forma:SolidPeso molecolare:461.49Verrucarin J
CAS:Verrucarin J, a Myrothecium fungus metabolite, triggers apoptosis in some cancer cells and fights Candida, Mucor, and JUNV (IC50: 1.2 ng/mL).Formula:C27H32O8Colore e forma:SolidPeso molecolare:484.54PAK4-IN-2
CAS:PAK4-IN-2 inhibits PAK4 with IC50 2.7 nM, arrests MV4-11 cells at G0/G1, and induces apoptosis, promising for cancer research.Formula:C18H21ClN6Colore e forma:SolidPeso molecolare:356.85PARP-1-IN-2
CAS:PARP-1-IN-2 is a potent PARP1 inhibitor that crosses the blood-brain barrier (IC50: 149 nM).PARP-1-IN-2 showed significant antiproliferative activity against
Formula:C22H15Cl2N3O2Purezza:98.82%Colore e forma:SolidPeso molecolare:424.28PD180970
CAS:PD180970 is an inhibitor of Bcr-Abl with IC50s of 5 nM, 0.8 nM and 50 nM for the autophosphorylation of p210Bcr-Abl, Src and Kit.Formula:C21H15Cl2FN4OPurezza:98.67%Colore e forma:SolidPeso molecolare:429.27Ref: TM-T23128
5mg55,00€10mg92,00€25mg137,00€50mg198,00€100mgPrezzo su richiesta1mL*10mM (DMSO)60,00€MIR002
CAS:MIR002: an oral POLA1/HDAC11 inhibitor with antitumor effects, enhances p53/p21, causes G1/S arrest, and triggers apoptosis.Formula:C27H29NO5Colore e forma:SolidPeso molecolare:447.52MI-192
CAS:MI-192: Selective HDAC2/3 inhibitor, IC50=30/16 nM, induces apoptosis in myeloid leukemia, potential in leukemia/anti-stroke treatment.Formula:C24H21N3O2Colore e forma:SolidPeso molecolare:383.44MSN-50
CAS:MSN-50, an inhibitor of Bax and Bak oligomerization, inhibits liposome permeabilization, prevents genotoxic cell death and promotes neuroprotection.Formula:C36H38BrN3O6Colore e forma:SolidPeso molecolare:688.61cRIPGBM
CAS:cRIPGBM induces apoptosis in GBM CSCs by targeting RIPK2, with an EC50 of 68 nM in GBM-1 cells.Formula:C26H20FN2O2Purezza:98%Colore e forma:SolidPeso molecolare:411.45LY5
CAS:LY5 is an inhibitor of STAT3 that acts by inhibiting cell viability, cell migration, and angiogenesis in medulloblastoma cells.Formula:C15H11N3O4SPurezza:98%Colore e forma:SolidPeso molecolare:329.33DPBQ
CAS:DPBQ (ZINC1620467) is a p53 activator.Formula:C24H14N2O2Purezza:98.08%Colore e forma:SolidPeso molecolare:362.38Ref: TM-T11092
1mg100,00€2mg149,00€5mg245,00€10mg354,00€25mg532,00€50mg735,00€100mg982,00€500mgPrezzo su richiestaIHMT-TRK-284
CAS:IHMT-TRK-284: Oral type II TRK inhibitor; targets TRKA, TRKB, TRKC (IC50s: 10.5, 0.7, 2.6 nM); selective and anti-tumor effective.Formula:C25H27N7OSColore e forma:SolidPeso molecolare:473.59Estramustine phosphate
CAS:Estramustine phosphate can be used to treat prostatic neoplasms; also has radiation protective properties.Formula:C23H32Cl2NO6PColore e forma:SolidPeso molecolare:520.38BRD4 Inhibitor-15
CAS:BRD4 Inhibitor-15 targets BRD4 with 18 nM IC50, induces apoptosis in 22RV1 cells, and lowers c-Myc, aiding prostate cancer research.Formula:C22H21N3O2Colore e forma:SolidPeso molecolare:359.42PDGFR-IN-1
CAS:PDGFR-IN-1 is a platelet-derived growth factor receptor (PDGFR) inhibitor, strongly inhibiting PDGFRα and PDGFRβ, useful for studying solid tumors.Formula:C25H30N8OPurezza:99.13% - 99.49%Colore e forma:SolidPeso molecolare:458.56Ref: TM-T62872
1mg170,00€5mg432,00€10mg655,00€25mg1.153,00€50mg1.665,00€100mg2.250,00€1mL*10mM (DMSO)434,00€CK2/ERK8-IN-1
CAS:TMCB inhibits CK2 (Ki: 0.25 µM), ERK8 (IC50: 0.50 µM), PIM1, DYRK1A, HIPK2 (Ki: 8.65-15.25 µM), and induces apoptosis.Formula:C11H9Br4N3O2Purezza:98.22%Colore e forma:SolidPeso molecolare:534.82(R)-STU104
CAS:(R)-STU104 is a TAK1-MKK3 protein-protein interaction (PPI) inhibitor. (R)-STU104 is a candidate compound for the treatment of ulcerative colitis.Formula:C18H18O4Purezza:98.91% - 99.42%Colore e forma:SolidPeso molecolare:298.33STAT3-IN-11
CAS:STAT3-IN-11 is a STAT3 inhibitor.STAT3-IN-11 promotes apoptosis in cancer cells and is a candidate compound for the treatment of cancer.Formula:C20H17NO4Purezza:98.3%Colore e forma:SolidPeso molecolare:335.35L6H21
CAS:L6H21 is an MD-2 inhibitor that can be used to study cognitive impairment and brain damage.Formula:C18H18O4Purezza:99.26%Colore e forma:SolidPeso molecolare:298.33Sibiriline
CAS:Sibiriline is a Receptor-Interacting Protein Kinase 1 inhibitor that acts by preventing immune-dependent hepatitis.Formula:C13H10N2OPurezza:98%Colore e forma:SolidPeso molecolare:210.23AK301
CAS:AK301 is a potent and selective inhibitor of tubulin polymerization and an effective sensitizer of cancer cells to apoptotic ligands (EC50 < 200 nM).Formula:C19H21ClN2O2Purezza:99.75%Colore e forma:SolidPeso molecolare:344.84Rhosin
CAS:Rhosin is a specific inhibitor of RhoA GTPases (Kd: ~0.4 uM), blocking RhoA-GEF interaction, not affecting Cdc42/Rac1/LARG, and induces apoptosis.Formula:C20H18N6OPurezza:98%Colore e forma:SolidPeso molecolare:358.4CRA-026440
CAS:CRA-026440(PCI-34051) is a highly potent HDAC inhibitor with inhibitory effects on HDAC1, HDAC2, HDAC3, HDAC6, HDAC8 and HDAC10 with Ki values of 4,14,11,15,7Formula:C23H24N4O4Purezza:96.42%Colore e forma:SolidPeso molecolare:420.46DRI-C21041
CAS:DRI-C21041 is a potent inhibitor of the CD40/CD40L interaction, demonstrating an inhibitory concentration 50 (IC50) value of 0.31 μM.Formula:C30H21N3O7SColore e forma:SolidPeso molecolare:567.57RIPK1-IN-11
CAS:RIPK1-IN-11, an oral RIPK1 blocker, Kd 9.2 nM, IC50 67 nM, prevents necrosis and inflammation in cells.Formula:C23H24N4O4SColore e forma:SolidPeso molecolare:452.53Anticancer agent 76
CAS:Compound CT2-3 is an anticancer agent that hinders growth, induces arrest, ROS, and apoptosis in NSCLC cells.Formula:C32H33NO5SColore e forma:SolidPeso molecolare:543.67Apogossypolone (ApoG2)
CAS:Apogossypolone (ApoG2) is a semi-synthesized derivative of gossypol which is a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins with K iFormula:C28H26O8Colore e forma:SolidPeso molecolare:490.5PD-1-IN-18
CAS:PD-1-IN-18 is a PD1 inhibitor of signaling pathway, and acts as an immunomodulator.Formula:C11H17N5O8Purezza:98%Colore e forma:SolidPeso molecolare:347.28ISC-4
CAS:ISC-4 is an Akt inhibitor, which activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model.Formula:C11H13NSeColore e forma:SolidPeso molecolare:238.19PARP1/BRD4-IN-1
CAS:PARP1/BRD4-IN-1 selectively inhibits PARP1 (49 nM IC50) and BRD4 (202 nM IC50), hindering pancreatic cancer cell growth.Formula:C29H26N6O3Colore e forma:SolidPeso molecolare:506.56DRAK1/2-IN-1
CAS:DRAK1/2-IN-1 is a potent inhibitor targeting both DRAK1 and DRAK2, displaying dissociation constants (Kd) of 1 µM and 6 µM, respectively.Formula:C22H24N2O3SColore e forma:SolidPeso molecolare:396.5PERK-IN-5
CAS:PERK-IN-5: oral PERK inhibitor, IC50 of 2 nM; blocks p-eIF2α at 9 nM; hinders tumor growth in renal cancer model.Formula:C25H26F2N4O3Colore e forma:SolidPeso molecolare:468.5Tubulin polymerization-IN-17
CAS:Compound 23g, a potent inhibitor of tubulin aggregation, induces apoptosis, and inhibits cell migration; promising for cancer research.Formula:C26H23NO5Colore e forma:SolidPeso molecolare:429.46Ludartin
CAS:Ludartin activates TRPA1, induces DNA damage, and lowers mitochondrial potential, yielding anticancer effects.Formula:C15H18O3Colore e forma:SolidPeso molecolare:246.3Mcl1-IN-4
CAS:Mcl1-IN-4 is an inhibitor of Mcl1 ( IC50:0.2 μM).Formula:C28H26N2O5SPurezza:98%Colore e forma:SolidPeso molecolare:502.58CU-3
CAS:CU-3 inhibits DGKalpha, reducing cancer growth and boosting anti-cancer immunity.Formula:C16H12N2O4S3Purezza:98%Colore e forma:SolidPeso molecolare:392.47EGFR-IN-57
CAS:EGFR-IN-57: potent EGFR-TK blocker, IC50 0.054 μM, oral. Halts VEGFR-2, CK2α, topo IIβ, tubulin. Causes G2/M, pre-G1 arrest, cancer cell death.Formula:C22H15N3O2SColore e forma:SolidPeso molecolare:385.44SZM-1209
CAS:SZM-1209 is a potent and specific RIPK1 inhibitor with oral activity, displaying a dissociation constant (Kd) of 85 nM.Formula:C31H29F5N4O5S2Purezza:98%Colore e forma:SolidPeso molecolare:696.71PI3Kδ/γ-IN-3
CAS:PI3Kδ/γ-IN-3 (Compound 58) is an orally active dual inhibitor of PI3Kδ (IC50: 1 nM) and PI3Kγ (IC50: 16 nM).Formula:C23H20ClN9OColore e forma:SolidPeso molecolare:473.92Justicidin B
CAS:Justicidin B: anticancer, proapoptotic, inhibits bone resorption & platelets, antiviral, fungicidal, antiprotozoal.Formula:C21H16O6Colore e forma:SolidPeso molecolare:364.35Metallo-β-lactamase-IN-5
CAS:Metallo-β-lactamase-IN-5 (compound 5c) is a powerful inhibitor of metallo-β-lactamases (MBLs).Formula:C19H16N4O3Colore e forma:SolidPeso molecolare:348.36HDAC1/6-IN-1
CAS:HDAC1/6-IN-1, a dual HDAC1 (89 nM) and HDAC6 (13 nM) inhibitor, blocks cancer cell cycle, triggers apoptosis, and halts metastasis.Formula:C32H45N7O4Colore e forma:SolidPeso molecolare:591.74PI3K-IN-34
CAS:PI3K-IN-34 targets PI3K-α/β/δ (IC50: 11.73/6.09/11.18 μM); potential leukemia research tool.Formula:C23H22N6O3Colore e forma:SolidPeso molecolare:430.46hGGPPS-IN-1
CAS:HGGPPS-IN-1: analog of C2-ThP-BPs, inhibits hGGPPS, triggers apoptosis in MM cells, shows anti-myeloma effects in vivo.Formula:C13H13N3O6P2SColore e forma:SolidPeso molecolare:401.27HIOC
CAS:TrkB agonist; shields neurons & retinas; crosses blood-brain & retinal barriers.Formula:C16H19N3O3Colore e forma:SolidPeso molecolare:301.34Berubicin HCl
CAS:Berubicin hydrochloride, a brain-penetrating anthracycline, disrupts DNA replication and repair by inhibiting topoisomerase II.Formula:C34H36ClNO11Colore e forma:SolidPeso molecolare:670.1AP23464
CAS:AP23464 inhibits Src/Abl kinases, effective on imatinib-resistant CML cells (IC50=14nM), blocks cell cycle, induces apoptosis, not against T315I mutant.Formula:C26H30N5O2PColore e forma:SolidPeso molecolare:475.52Antitumor agent-57
CAS:Antitumor agent-57 (Compound 3o) is a potent NQO1-directed antitumor compound.Formula:C20H15NO5Colore e forma:SolidPeso molecolare:349.34CMC2.24
CAS:CMC2.24 inhibits Ras and ERK1/2, fights pancreatic tumors in mice, blocks MMPs (IC50: 2-69 µM), and reduces osteoarthritis by stabilizing cartilage.Formula:C26H21NO5Colore e forma:SolidPeso molecolare:427.45
