Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(1 prodotti)
- Caspasi(154 prodotti)
- FOXO1(2 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(126 prodotti)
- PDK(9 prodotti)
- PERK(23 prodotti)
- Chinasi di serina/treonina(17 prodotti)
- Survivin(14 prodotti)
- TNF(91 prodotti)
- c-RET(61 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 6170 prodotti di "Apoptosi"
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Trehalose 6-behenate
CAS:Trehalose 6-behenate is a Th1/Th17 skewing vaccine adjuvant.Formula:C34H64O12Purezza:98%Colore e forma:SolidPeso molecolare:664.86VEGFR-2-IN-22
CAS:VEGFR-2-IN-22 blocks VEGFR-2/beta-tubulin, IC50=19.82 nM, induces apoptosis.Formula:C26H24ClFN4O6Colore e forma:SolidPeso molecolare:542.94IQDMA
CAS:IQDMA is an inhibitor of the transcription factor STAT5.Formula:C19H20N4Colore e forma:SolidPeso molecolare:304.39SGC-STK17B-1
CAS:SGC-STK17B-1 is a potent and selective inhibitor of STK17B/DRAK2 kinase.Formula:C16H10N2O2S3Colore e forma:SolidPeso molecolare:358.46Anticancer agent 50
CAS:Anticancer agent 50 targets ABCB1 pump, has cytotoxic effects, alters cyclin D1/p53, and shows promise in T lymphoma research.Formula:C30H32N2O4SeColore e forma:SolidPeso molecolare:563.55YC-137
CAS:YC-137 inhibits BCL-2, triggers apoptosis in Bcl-2-high cells, and blocks its anti-apoptotic function.Formula:C24H21N3O6S2Colore e forma:SolidPeso molecolare:511.57R-547 mesylate
CAS:R547 Mesylate is a potent ATP-competitive inhibitor of CDK1, CDK2, CDK4 with Ki value of 2 nM, 3 nM, 1 nM respectively.Formula:C19H25F2N5O7S2Colore e forma:SolidPeso molecolare:537.56Epinephrine bitartrate
CAS:L-Epinephrine Bitartrate is alpha- and beta-adrenergic receptor stimulator.Formula:C13H19NO9Purezza:99.07% - 99.94%Colore e forma:White SolidPeso molecolare:333.3(4R,9S)-AG 205
CAS:AG-205 is a potent inhibitor of FabK, the enoyl-ACP reductase in Streptococcus pneumoniae.Formula:C22H23ClN6OSColore e forma:SolidPeso molecolare:454.98Rooperol
CAS:Rooperol: a norlignan with p38α inhibiting, immunomodulatory, antitumor, antibacterial, anticonvulsant, and antioxidant properties.Formula:C17H14O4Purezza:98%Colore e forma:SolidPeso molecolare:282.29STAT3-IN-10
CAS:STAT3-IN-10 (A11) inhibits STAT3; halts tumor growth and triggers apoptosis in cancer cells (IC 50 = 5.18 μM).Formula:C17H13NO5Colore e forma:SolidPeso molecolare:311.29Bcl-2-IN-9
CAS:Bcl-2-IN-9: a novel, selective Bcl-2 inhibitor inducing apoptosis in leukemia with an IC50 of 2.9 μM; low cytotoxicity.Formula:C27H31N7O3SColore e forma:SolidPeso molecolare:533.65F5446
CAS:F5446 is a selective small molecule SUV39H1 methyltransferase inhibitor, promotes apoptosis in colorectal cancer cells by inhibiting the deposition of H3K9me3.Formula:C26H17ClN2O8SPurezza:98.56%Colore e forma:SolidPeso molecolare:552.94Ref: TM-T71890
1mg90,00€5mgPrezzo su richiesta10mgPrezzo su richiesta1mL*10mM (DMSO)Prezzo su richiestaMethylisothiazolinone
CAS:Methylisothiazolinone (MI) is a powerful synthetic biocide and preservative within the group of isothiazolinones.Formula:C4H5NOSPurezza:99.78%Colore e forma:Colorless Prisms LiquidPeso molecolare:115.15EGFR/BRAFV600E-IN-1
CAS:EGFR/BRAFV600E-IN-1 inhibits EGFR (0.08 μM) & BRAFV600E (0.15 μM), affects A-549, MCF-7, Panc-1 & HT-29 (IC50: 0.79-1.3 μM).Formula:C24H24ClN3O3Colore e forma:SolidPeso molecolare:437.92MDM2/XIAP-IN-3
CAS:MDM2/XIAP-IN-3 (compound 3e), a dual inhibitor of MDM2/XIAP, diminishes MDM2 and XIAP protein levels while augmenting p53 expression, consequently suppressingFormula:C29H30N2O5SColore e forma:SolidPeso molecolare:518.62DNA topoisomerase II inhibitor 1
CAS:Potent DNA topoisomerase II blocker; arrests cell cycle, induces apoptosis, anti-growth effects.Formula:C28H24N4O3SColore e forma:SolidPeso molecolare:496.58CS1
CAS:CS1: potent topoisomerase II alpha inhibitor, broad-spectrum antitumor, low toxicity, anti-resistance, induces DNA damage, G2/M arrest, apoptosis.Formula:C16H12O3Colore e forma:SolidPeso molecolare:252.26CA224
CAS:CA224: selective oral Cdk4-cyclin D1 inhibitor, IC50=6.2μM, promotes apoptosis, has antitumor effects.Formula:C24H22N2OColore e forma:SolidPeso molecolare:354.44Topoisomerase IIα-IN-3
CAS:Topoisomerase IIα-IN-3 is a DNA-inserting topoisomerase-Iiα inhibitor that blocks the cell cycle in G0/G1 phase and induces apoptosis.Formula:C29H20N6O2SColore e forma:SolidPeso molecolare:516.57EGFR-IN-59
CAS:EGFR-IN-59: EGFR inhibitor, IC50 = 190 nM, induces apoptosis, cytotoxic to A549 cells (IC50 = 8.62 μM) and WI38 cells (IC50 = 52.6 μM). Use: Various cancers.Formula:C27H23N5O4SColore e forma:SolidPeso molecolare:513.57(rel)-Oxaliplatin
CAS:(rel)-Oxaliplatin, a DNA inhibitor, induces crosslinks, hinders replication/transcription, and triggers apoptosis; used in cancer studies.Formula:C8H14N2O4PtColore e forma:SolidPeso molecolare:397.29Necrostatin-7
CAS:Necrostatin-7 (Necrostatin 7) is a necrotic apoptosis inhibitor with cardioprotective effects that inhibits RANK-NFATc1 signaling.Formula:C16H10FN5OS2Purezza:98.71%Colore e forma:SolidPeso molecolare:371.41Flonoltinib
CAS:Flonoltinib (JAK2/FLT3-IN-1) is an orally active and efficient JAK2/FLT3 inhibitor with anti-cancer properties.Formula:C25H34FN7OPurezza:99.52%Colore e forma:SolidPeso molecolare:467.58YM-155 hydrochloride
CAS:Sepantronium hydrochloride (YM-155 hydrochloride) is a novel survivin suppressant that inhibits survivin promoter with an IC 50 of 0.54 nM[1].Formula:C20H19ClN4O3Colore e forma:SolidPeso molecolare:398.85Nafamostat hydrochloride
CAS:Nafamostat hydrochloride is a synthetic serine protease inhibitor and is an anticoagulant.Formula:C19H19Cl2N5O2Purezza:98%Colore e forma:SolidPeso molecolare:420.29MBC-11
CAS:MBC-11: First bone-targeting bisphosphonate-etidronate conjugate with araC, may treat TIBD.Formula:C11H20N3O14P3Purezza:>99.99% - >99.99%Colore e forma:SolidPeso molecolare:511.21Caspase-3-IN-1
CAS:Caspase-3-IN-1 is a potent inhibitor of Caspase-3 (IC50: 14.5 nM).Formula:C26H25N3O6SColore e forma:SolidPeso molecolare:507.56RIPK1-IN-15
CAS:RIPK1-IN-15 (Compound 2.5) is a potent RIPK1 inhibitor that has the potential in neurodegenerative, autoimmune, and inflammatory diseases research [1].Formula:C19H19N3O2Colore e forma:SolidPeso molecolare:321.37Anti-inflammatory agent 15
CAS:Compound 29, anti-inflammatory and antimycobacterial, halts Mtb H37Rv and M299 growth; MIC50 at 2.3 and 7.8 μM. Blocks iNOS, TNF-α, IL-1β.Formula:C17H20N2SColore e forma:SolidPeso molecolare:284.42PDMP (hydrochloride)
CAS:PDMP, a glucosylceramide synthase inhibitor with 4 stereoisomers, acts at 0.8μM; D-threo enantiomer also blocks lactosylceramide synthesis.Formula:C23H39ClN2O3Colore e forma:SolidPeso molecolare:427.03VU 0364739 hydrochloride
CAS:VU 0364739 hydrochloride (VU 0364739 HCl) is a phospholipase D2 (PLD2) inhibitor that induces apoptosis and can be used in cancer research.Formula:C26H28ClFN4O2Purezza:99.36%Colore e forma:SolidPeso molecolare:482.98Apoptosis inducer 8
CAS:Apoptosis inducer 8 is a galectin-1 (gal-1)-mediated apoptosis inducer and a PET imaging agent that significantly reduces gal-1 protein levels and can be usedFormula:C29H22ClN5O2Colore e forma:SolidPeso molecolare:507.97MSN-125
CAS:MSN-125 inhibits Bax/Bak apoptosis, protects neurons, prevents MOMP with IC50 of 4μM.Formula:C36H38BrN3O6Purezza:98%Colore e forma:SolidPeso molecolare:688.61Dinoprost
CAS:Dinoprost (Prostaglandin F2a) is a naturally occurring prostaglandin. It is used in medicine to induce labor and as an abortifacient.Formula:C20H34O5Purezza:97.94% - 98.04%Colore e forma:White To Off-White Crystalline SolidPeso molecolare:354.48Ref: TM-T15133
5mg49,00€10mg74,00€25mg137,00€50mg205,00€100mg326,00€200mg485,00€1mL*10mM (DMSO)54,00€MeOIstPyrd
CAS:MeOIstPyrd is an anti-skin cancer agent that inhibits cell proliferation, migration, and spheroid formation through activation of the mitochondrial intrinsicFormula:C14H16N4O2SColore e forma:SolidPeso molecolare:304.37PWT33597 mesylate
CAS:PWT33597 (VDC-597) is an oral PI3K alpha/mTOR dual inhibitor, potentially causing cancer cell death and growth inhibition.Formula:C27H34F2N8O7S2Colore e forma:SolidPeso molecolare:684.7348hCAIX-IN-12
CAS:hCAIX-IN-12: hCAIX inhibitor; IC50: 0.74 μM (CAIX), 10.78 μM (CAII); impedes cell growth, triggers apoptosis, boosts ROS; potential in CRC research.Formula:C18H14N4O3S2Colore e forma:SolidPeso molecolare:398.46MDM2/XIAP-IN-2
CAS:MDM2/XIAP-IN-2 is a dual inhibitor targeting murine double minute 2 (MDM2) and X-linked inhibitor of apoptosis protein (XIAP).Formula:C29H32N2O4SColore e forma:SolidPeso molecolare:504.64HDAC-IN-31
CAS:HDAC-IN-31: Oral HDAC inhibitor; targets HDAC1, 2, 3; weak on HDAC8; potential in fighting lymphoma.Formula:C25H24N4O2Colore e forma:SolidPeso molecolare:412.48TSI-13-57
CAS:TSI-13-57 is a MyD88 inhibitor or pan-TLR inhibitor that suppresses MyD88 TIR domain dimerization ,inhibits LPS-induced TNF-α (IC50 = 6.73 mM).Formula:C28H29N3O3Purezza:99.63%Colore e forma:SolidPeso molecolare:455.55RIP1 kinase inhibitor 6
CAS:RIP1 Kinase Inhibitor 6 is a potent and selective inhibitor of RIP1 kinase, demonstrating inhibitory activity with an IC50 of less than 100 nM in a human R1P1Formula:C19H18F2N2O3Purezza:98%Colore e forma:SolidPeso molecolare:360.35Penehyclidine hydrochloride
CAS:Penehyclidine hydrochloride: M1/M3 antagonist, activates NF-κB, anti-inflammatory, anticholinergic.Formula:C20H30ClNO2Purezza:99.79% - 99.91%Colore e forma:SolidPeso molecolare:351.91Prexasertib mesylate
CAS:Prexasertib (LY2606368), a Chk1/2 inhibitor, enhances therapy in acute lymphoblastic leukemia, causing DNA damage and antitumor effects.Formula:C19H23N7O5SPurezza:98%Colore e forma:SolidPeso molecolare:461.49GRI977143
CAS:GRI977143: selective LPA2 agonist (EC50=3.3μM), blocks caspases 3/7/8/9, limits DNA fragmentation.Formula:C22H17NO4SPurezza:99.08%Colore e forma:SolidPeso molecolare:391.44RIPK3-IN-2
CAS:RIPK3-IN-2 is a RIP3 inhibitor that can be used in studies of diseases caused by or associated with activated necrotic pathways.Formula:C21H16ClN3O2S2Colore e forma:SolidPeso molecolare:441.95PARP-2-IN-3
CAS:PARP-2-IN-3 is used in the study of breast cancer as a PARP-2 inhibitor with antitumor activity that induces apoptosis (apoptosis) and necrosis in cancer cells.
Formula:C20H20ClN3O3Purezza:99.33%Colore e forma:SolidPeso molecolare:385.84Mcl1-IN-4
CAS:Mcl1-IN-4 is an inhibitor of Mcl1 ( IC50:0.2 μM).Formula:C28H26N2O5SPurezza:98%Colore e forma:SolidPeso molecolare:502.58A-385358
CAS:A-385358 is a selective Bcl-xL inhibitor with Kis of 0.80 nM for Bcl-xL and 67 nM for Bcl-2, respectively.Formula:C32H41N5O5S2Purezza:99.97%Colore e forma:SolidPeso molecolare:639.83Ref: TM-T14071
1mg57,00€5mg109,00€10mg165,00€25mg268,00€50mg400,00€100mg567,00€1mL*10mM (DMSO)158,00€AG6033
CAS:AG6033, a novel CRBN modulator, degrades GSPT1/IKZF1 and inhibits various tumors.Formula:C30H23N5O4Colore e forma:SolidPeso molecolare:517.53(S)-Elobixibat
CAS:(S)-Elobixibat is the S-isomer of Elobixibat. It is an orally active inhibitor of Apical Sodium-Dependent Bile (IBAT) and can reduce LDL cholesterol, increase serum GLP-1, and promote colonic motility. This compound shows potential for treating metabolic syndrome and can be studied for constipation, dyslipidemia, non-alcoholic hepatitis, and liver tumors.Formula:C36H45N3O7S2Colore e forma:SolidPeso molecolare:695.89CT-1
CAS:CT-1 is a DNA minor groove ligand and causes p53-dependent breast cancer cell apoptosis.
Formula:C29H23F3N4OPurezza:99.79%Colore e forma:SolidPeso molecolare:500.51Ref: TM-T27093
1mg115,00€5mg249,00€10mg368,00€25mg562,00€50mg787,00€100mg1.054,00€500mgPrezzo su richiestaRDR03871
CAS:RDR03871 is an MDM2 inhibitor.
Formula:C18H16ClF3N6Purezza:97.78%Colore e forma:SolidPeso molecolare:408.81Ethacridine
CAS:Ethacridine acts as an inhibitor of poly (ADP-ribose) glycohydrolase (PARG) and functions as an activator of transcriptional coactivators. It induces apoptosis in thyroid cancer cells and promotes the differentiation of thyroid follicular cells.Formula:C15H15N3OColore e forma:SolidPeso molecolare:253.30STAT5-IN-2
CAS:STAT5-IN-2 is an inhibitor of STAT5 with antileukemic effects (EC50s: 9 μM and 5 μM in K562 and KU812 cells, respectively).Formula:C26H27N3OPurezza:99.55%Colore e forma:SolidPeso molecolare:397.51Ref: TM-T16940
1mg58,00€5mg110,00€10mg182,00€25mg289,00€50mg399,00€100mg530,00€200mg717,00€1mL*10mM (DMSO)122,00€MpsBAY2a
CAS:carcinoma cell proliferation.Formula:C29H28N6OPurezza:98%Colore e forma:SolidPeso molecolare:476.57AK301
CAS:AK301 is a potent and selective inhibitor of tubulin polymerization and an effective sensitizer of cancer cells to apoptotic ligands (EC50 < 200 nM).Formula:C19H21ClN2O2Purezza:99.75%Colore e forma:SolidPeso molecolare:344.84CN128 hydrochloride
CAS:CN128 hydrochloride is an oral, selective hydroxypyridone iron chelator for β-thalassemia research.
Formula:C15H18ClNO3Colore e forma:SolidPeso molecolare:295.76QM31
CAS:QM31 is a selective Apaf-1 inhibitor(inbitita formation of the apoptosome with IC50 of 7.9μM).Formula:C39H38Cl4N4O4Purezza:98%Colore e forma:SolidPeso molecolare:768.56RIPK1-IN-12
CAS:RIPK1-IN-12: Strong RIPK1 blocker, hinders necroptosis; EC50=1.6 nM (human), 2.9 nM (mouse).Formula:C24H26N4O3SColore e forma:SolidPeso molecolare:450.55Topoisomerase II inhibitor 3
CAS:Acridone-based Topoisomerase II inhibitor 3 targets topo IIα/β (IC50: 0.17μM α, 0.23μM β), causes DNA damage, and induces apoptosis.Formula:C18H20N4O4Colore e forma:SolidPeso molecolare:356.38NOC-5
CAS:NOC-5 is an NO donor that induces airway relaxation and concentration-dependently triggers 10 μM DAF-2 fluorescence.Formula:C6H16N4O2Purezza:98%Colore e forma:SolidPeso molecolare:176.22FKGK 18
CAS:FKGK 18: GVIA iPLA2 inhibitor, 99.9% at 0.091 fraction, selective, IC50 ~50 nM–3 μM, reduces blood glucose and diabetes in NOD mice.Formula:C16H15F3OColore e forma:SolidPeso molecolare:280.28MMP-9-IN-4
CAS:MMP-9-IN-4 inhibits MMP-9 (IC50=7.46nM) and AKT (IC50=8.82nM), induces apoptosis and is used in cancer research.Formula:C28H19F3N4O6Colore e forma:SolidPeso molecolare:564.47USP7-IN-4
CAS:USP7-IN-4 is a non-competitive, potent and selective inhibitor of USP7, up-regulates p53 and p21, down-regulates MDM2,anti-proliferativity RS4;11 (leukemia) .Formula:C29H34N6O3Purezza:98.27% - 99.09%Colore e forma:SolidPeso molecolare:514.62FW1256
CAS:FW1256: phenyl analog, slow H2S donor, inhibits NF-κB, induces apoptosis, anti-inflammatory, potential cancer/cardio treatment.Formula:C12H10NOPSColore e forma:SolidPeso molecolare:247.25DNL343
CAS:DNL343 is an eIF2B activator that inhibits stress granule (SG) assembly induced by the C9ORF72 dipeptide repeat.Formula:C20H19ClF3N3O4Purezza:99.96%Colore e forma:SolidPeso molecolare:457.83VRT-043198
CAS:VRT-043198, a VX-765 metabolite, is a potent ICE/caspase-1 inhibitor, crossing the blood-brain barrier with K i of 0.8/0.6 nM.Formula:C22H29ClN4O6Colore e forma:SolidPeso molecolare:480.94Mutant p53 modulator-1
CAS:Mutant p53 modulator-1 inhibits cancer with p53 mutations; see patent WO2021231474A1, compound 231B.Formula:C27H32F4N8O2Colore e forma:SolidPeso molecolare:576.59Apoptotic agent-2
CAS:Apoptotic agent-2 reduces Bcl-2, boosts Bax & caspase-3, inducing apoptosis for cancer research.Formula:C25H16ClN7SColore e forma:SolidPeso molecolare:481.96PDE5-IN-3
CAS:PDE5-IN-3: Inhibits PDE5 (1.57 nM), EGFR (5.827 μM), Wnt pathway (1286.96 ng/mL), induces apoptosis, and has antitumor effects.Formula:C21H14BrN5O2Colore e forma:SolidPeso molecolare:448.27AMC-01
CAS:AMC-01 has potential antiviral activity and induces dose- and time-dependent inactivation of eIF2-α via phosphorylation of serine residue 51.Formula:C27H27BrN2O6Purezza:99.95%Colore e forma:SolidPeso molecolare:555.42ORY-1001 free base
CAS:ORY-1001: potent KDM1A inhibitor (IC50 <20nM), selective, affects THP-1 cell gene regulation and apoptosis, hinders MV(4;11) cell growth (EC50 <1nM).Formula:C15H22N2Purezza:98%Colore e forma:SolidPeso molecolare:230.35CCCI-01
CAS:CCCI-01: Centrosome cluster inhibitor with anticancer properties, induces apoptosis, aids in non-cross-resistant drug research.Formula:C11H9N3O4Purezza:99.97%Colore e forma:SolidPeso molecolare:247.21NPD4928
CAS:NPD4928 boosts cancer cell sensitivity to GPX4 inhibitors, hinting at therapeutic potential through ferroptosis.Formula:C29H32N2O6Colore e forma:SolidPeso molecolare:504.57RET-IN-12
CAS:RET-IN-12 is a RET inhibitor capable of acting on RET(WT) (IC50: 0.3 nM) and RET(V804M) (IC50: 1 nM).Formula:C30H30F3N5O4Colore e forma:SolidPeso molecolare:581.59ICG-001
CAS:ICG001 is a β-catenin/TCF-mediated transcription inhibitor that selectively blocks β-catenin/CBP interaction.Cost-effective and quality-assured.Formula:C33H32N4O4Purezza:99.55% - 99.62%Colore e forma:SolidPeso molecolare:548.63Ref: TM-T6113
1mg34,00€5mg66,00€10mg101,00€25mg197,00€50mg341,00€100mg530,00€500mg1.134,00€1mL*10mM (DMSO)81,00€PI3Kδ/γ-IN-3
CAS:PI3Kδ/γ-IN-3 (Compound 58) is an orally active dual inhibitor of PI3Kδ (IC50: 1 nM) and PI3Kγ (IC50: 16 nM).Formula:C23H20ClN9OColore e forma:SolidPeso molecolare:473.92SZM-1209
CAS:SZM-1209 is a potent and specific RIPK1 inhibitor with oral activity, displaying a dissociation constant (Kd) of 85 nM.Formula:C31H29F5N4O5S2Purezza:98%Colore e forma:SolidPeso molecolare:696.71LY5
CAS:LY5 is an inhibitor of STAT3 that acts by inhibiting cell viability, cell migration, and angiogenesis in medulloblastoma cells.Formula:C15H11N3O4SPurezza:98%Colore e forma:SolidPeso molecolare:329.33CU-3
CAS:CU-3 inhibits DGKalpha, reducing cancer growth and boosting anti-cancer immunity.Formula:C16H12N2O4S3Purezza:98%Colore e forma:SolidPeso molecolare:392.47HL271
CAS:HL271, a derivative of metformin, is a potent AMPK activator that increases AMPK phosphorylation. HL271 attenuates aging-associated cognitive impairment.Formula:C13H17ClF3N5OPurezza:98%Colore e forma:SolidPeso molecolare:351.76IDT
CAS:IDT, an oral TNFα modulator, changes neutrophil levels, boosts cognition, and reduces tau/amyloid in 3xTgAD mice.Formula:C8H5NS2Purezza:98%Colore e forma:SolidPeso molecolare:179.26DRAK1/2-IN-1
CAS:DRAK1/2-IN-1 is a potent inhibitor targeting both DRAK1 and DRAK2, displaying dissociation constants (Kd) of 1 µM and 6 µM, respectively.Formula:C22H24N2O3SColore e forma:SolidPeso molecolare:396.5ISC-4
CAS:ISC-4 is an Akt inhibitor, which activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model.Formula:C11H13NSeColore e forma:SolidPeso molecolare:238.19PD-1-IN-18
CAS:PD-1-IN-18 is a PD1 inhibitor of signaling pathway, and acts as an immunomodulator.Formula:C11H17N5O8Purezza:98%Colore e forma:SolidPeso molecolare:347.28PAK4-IN-2
CAS:PAK4-IN-2 inhibits PAK4 with IC50 2.7 nM, arrests MV4-11 cells at G0/G1, and induces apoptosis, promising for cancer research.Formula:C18H21ClN6Colore e forma:SolidPeso molecolare:356.85HDACs/mTOR Inhibitor 1
CAS:HDACs/mTOR Inhibitor 1 is a dual HDACs and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies (IC50s: 0.19 nM, 1.8 nM,Formula:C28H38N8O5Colore e forma:SolidPeso molecolare:566.65Anticancer agent 76
CAS:Compound CT2-3 is an anticancer agent that hinders growth, induces arrest, ROS, and apoptosis in NSCLC cells.Formula:C32H33NO5SColore e forma:SolidPeso molecolare:543.67PS121912
CAS:PS121912 is a potent and selective inhibitor of VDR-coactivator.Formula:C24H21F3N2OPurezza:98%Colore e forma:SolidPeso molecolare:410.43BCL6-IN-8c
CAS:BCL6-IN-8c is an orally active and potent inhibitor of B-cell lymphoma 6 (BCL6)-corepressor interaction(IC50 of 0.10 μM in cell-free enzyme-linked immunosorbentFormula:C20H20ClN3O5Colore e forma:SolidPeso molecolare:417.84Pentabromophenol
CAS:Pentabromophenol (NSC-5717) suppressed TGF-β response by accelerating the turnover rate of TGF-β receptors.Formula:C6HBr5OPurezza:99.83%Colore e forma:Monoclinic Prisms From Acetic Acid; Needles From Alcohol Physical Description Light Brown Powder Insoluble In Water (Ntp 1992)Peso molecolare:488.59Bax activator-1
CAS:Bax activator-1 (compound 106) is a Bax activator. It induces Bax-dependent tumor cell apoptosis[1].Formula:C29H36N4O3Colore e forma:SolidPeso molecolare:488.62RIPK1-IN-11
CAS:RIPK1-IN-11, an oral RIPK1 blocker, Kd 9.2 nM, IC50 67 nM, prevents necrosis and inflammation in cells.Formula:C23H24N4O4SColore e forma:SolidPeso molecolare:452.53DPQZ
CAS:DPQZ is an anti-tubulin compound acting by inducing cell apoptosis in human oral cancer cells through Ras/Raf inhibition and MAP kinases activation.Formula:C20H17N3OPurezza:98%Colore e forma:SolidPeso molecolare:315.37SKLB70326
CAS:SKLB70326 is a cell-cycle progression inhibitor that acts by inducing G0/G1 phase arrest and apoptosis in human hepatic carcinoma cells.Formula:C15H13N3O2SPurezza:98%Colore e forma:SolidPeso molecolare:299.35Antitumor agent-56
CAS:Antitumor-56: Oral triptolide derivative; inhibits melanoma; anti-tumor, anti-inflammatory, NO-releasing properties.Formula:C28H28N2O10SColore e forma:SolidPeso molecolare:584.59Aurora A inhibitor 2
CAS:Aurora A inhibitor 2 (Compound 16h) is a potent inhibitor of Aurora A kinase (IC50: 21.94 nM).Formula:C24H26N6O3Colore e forma:SolidPeso molecolare:446.5NSC-741909
CAS:NSC-741909 is an anticancer agent that acts by suppressing the growth of several cell lines.Formula:C16H14ClNOPurezza:98%Colore e forma:SolidPeso molecolare:271.74Mammea A/BA
CAS:Mammea A/BA combats T. cruzi by causing mitochondrial damage, ROS, DNA fragmentation, and vacuolization, leading to cell death. Useful for Chagas research.Formula:C25H26O5Colore e forma:SolidPeso molecolare:406.47
