Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(1 prodotti)
- Caspasi(154 prodotti)
- FOXO1(2 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(134 prodotti)
- PDK(9 prodotti)
- PERK(23 prodotti)
- Chinasi di serina/treonina(17 prodotti)
- Survivin(14 prodotti)
- TNF(93 prodotti)
- c-RET(61 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 6223 prodotti di "Apoptosi"
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Mcl1-IN-9
CAS:Mcl1-IN-9 is a potent myeloid cell leukemia-1 (Mcl-1) Inhibitor with an IC50 of 446 nM in reengineered BCR-ABL+ B-ALL cells and a Ki of 0.03 nM.Formula:C37H39ClN4O4Purezza:98%Colore e forma:SolidPeso molecolare:639.18Anti-inflammatory agent 47
CAS:Flo8, an anti-inflammatory and antioxidant agent, effectively suppresses the release of reactive oxygen species (ROS) and nitric oxide (NO) while inhibitingFormula:C25H18N2O3Purezza:98%Colore e forma:SolidPeso molecolare:394.42PHA-680626
CAS:PHA-680626 is a PLK inhibitor, effective on resistant leukemia cells, with IC50: Plk1 (0.53 μM), Plk2 (0.07 μM), Plk3 (1.61 μM).Formula:C23H26N6O2SColore e forma:SolidPeso molecolare:450.56LG308
CAS:LG308, a synthetic compound, has anti-tumor properties, inducing apoptosis and mitotic arrest, thereby suppressing prostate cancer growth.Formula:C19H17FN2OColore e forma:SolidPeso molecolare:308.35HJC-0123
CAS:HJC-0123: inhibits STAT3, boosts cleaved caspase-3, hinders cell growth, triggers apoptosis, effective in ER-negative breast/pancreatic cancer.Formula:C24H16N2O3SColore e forma:SolidPeso molecolare:412.46KS106
CAS:KS106 inhibits ALDH (1A1: 334 nM, 2: 2137 nM, 3A1: 360 nM), has anti-cancer properties, raises ROS, and promotes aldehyde build-up.Formula:C18H15BrF3N3O2SPurezza:99.31%Colore e forma:SolidPeso molecolare:474.3CT-1
CAS:CT-1 is a DNA minor groove ligand and causes p53-dependent breast cancer cell apoptosis.
Formula:C29H23F3N4OPurezza:99.79%Colore e forma:SolidPeso molecolare:500.51Ref: TM-T27093
500mgPrezzo su richiesta1mg115,00€5mg249,00€10mg368,00€25mg562,00€50mg787,00€100mg1.054,00€DNL343
CAS:DNL343 is an eIF2B activator that inhibits stress granule (SG) assembly induced by the C9ORF72 dipeptide repeat.Formula:C20H19ClF3N3O4Purezza:99.96%Colore e forma:SolidPeso molecolare:457.83Ferroptosis inducer-1
CAS:Ferroptosis inducer-1 is a Ferroptosis inducer with antitumor potential .Formula:C25H21ClN2O5Colore e forma:SolidPeso molecolare:464.9AMPK activator 11
CAS:AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-Formula:C25H20N4O2Purezza:98%Colore e forma:SolidPeso molecolare:408.45YLT205
CAS:YLT205 is an inducer of apoptosis in human colorectal cells that acts by inhibiting tumor growth.Formula:C16H12BrClN4O2S2Purezza:98%Colore e forma:SolidPeso molecolare:471.78CCT373566
CAS:CCT373566: potent BCL6 degrader, oral, IC50 2.2 nM; hinders cell growth in vitro & shrinks tumors in vivo.Formula:C26H29ClF2N6O3Colore e forma:SolidPeso molecolare:547Oxythiamine chloride HCl
CAS:Oxythiamine chloride is a thiamine antagonist and anticancer agent that inhibits transketolase, affecting RNA/DNA synthesis and inducing apoptosis.Formula:C12H17Cl2N3O2SColore e forma:SolidPeso molecolare:338.25Apoptotic agent-3
CAS:"Apoptotic agent-3 targets Bcl-2/Bax, activates caspase-3, and has anti-proliferative properties for cancer research."Formula:C31H21N5OSColore e forma:SolidPeso molecolare:511.6BMS-566394
CAS:BMS-566394 is a potent, exceptionally selective inhibitor of TNF-α converting enzyme (TACE).Formula:C22H21F3N4O4Colore e forma:SolidPeso molecolare:462.42Aurora kinase-IN-1
Aurora kinase-IN-1: potent aurora kinase inhibitor, alters G1 cycle proteins, induces G1/S arrest and apoptosis, potential chemotherapy lead.Formula:C30H25Br2N3O5Colore e forma:SolidPeso molecolare:667.34SMU127
CAS:SMU127 is an agonist of the toll-like receptor 1/2 (TLR1/2) heterodimer.Formula:C16H23N3O3SColore e forma:SolidPeso molecolare:337.44Ceranib-2
CAS:Ceranib-2, a ceramidase inhibitor (IC50: 28 μM, SKOV3), reduces sphingosine/S1P and promotes apoptosis, showing anticancer properties.Formula:C25H19NO3Purezza:98.49%Colore e forma:SolidPeso molecolare:381.42Infliximab
CAS:Infliximab is a chimeric monoclonal antibody that inhibits TNF-α. Infliximab can be used to treat Crohn's disease and rheumatoid arthritis. Cost-effective and quality-assured.Purezza:98% - 99.70%Colore e forma:LiquidPeso molecolare:145.98 kDap53 Activator 5
CAS:Potent p53 Activator 5, SC150 <0.05 mM, restores mutant p53 DNA binding, exhibits anti-tumor properties.Formula:C29H32F6N4OColore e forma:SolidPeso molecolare:566.58Esuberaprost Sodium
CAS:Famitinib (SHR1020), an oral drug, inhibits c-kit, VEGFR-2, and PDGFRβ (IC50: 2.3/4.7/6.6 nM) and triggers apoptosis in gastric cancer.Formula:C23H27FN4O2Colore e forma:SolidPeso molecolare:410.48MMP2-IN-1
CAS:MMP2-IN-1, an MMP2 inhibitor (IC50 = 6.8μM), halts growth and induces apoptosis in some cancers.Formula:C15H13NO5SColore e forma:SolidPeso molecolare:319.33KU-0058948
CAS:KU-0058948: PARP inhibitor, triggers cell cycle arrest and apoptosis in myeloid leukemia cells in vitro.Formula:C21H21FN4O2Colore e forma:SolidPeso molecolare:380.42Vin-C01
CAS:Vin-C01, a potent protector of pancreatic β-cells (EC50=0.22μM), aids in type 2 diabetes research by preventing STZ-induced β-cell apoptosis.Formula:C20H24N2OColore e forma:SolidPeso molecolare:308.42RO2468
CAS:RO2468 is a potent and orally active inhibitor of the p53-MDM2.Formula:C30H30Cl2FN5O4Purezza:98%Colore e forma:SolidPeso molecolare:614.49TH-Z835
CAS:TH-Z835 is a selective inhibitor for the KRAS (G12D) mutation, demonstrating an inhibitory concentration (IC50) of 1.6 μM.Formula:C30H38N6OPurezza:98%Colore e forma:SolidPeso molecolare:498.66ZC0101
CAS:ZC0101: potent oral IDO1/TrxR inhibitor. IC50: 0.084/7.98 μM. Induces apoptosis, ROS in cancer cells.Formula:C17H15N3O2Colore e forma:SolidPeso molecolare:293.32EGFR-IN-60
CAS:EGFR-IN-60: oral anticancer drug, inhibits EGFR/JAK3, effective on H1975/A431 cells, promotes apoptosis.Formula:C28H28Cl2N6OColore e forma:SolidPeso molecolare:535.47Melflufen
CAS:Melflufen, a dipeptide prodrug of Melphalan, is an alkylating agent with strong antitumor activity in MM, causing DNA damage and cytotoxicity.Formula:C24H30Cl2FN3O3Purezza:97.056%Peso molecolare:498.42VU0285655-1
CAS:VU0285655-1, a PLD2 inhibitor, halts PLD2-deficient cell growth and protects against high glucose-induced cell death. Used in diabetic retinopathy research.Formula:C25H27N5O2Purezza:99.73%Colore e forma:SolidPeso molecolare:429.51BLM-IN-2
BLM-IN-2: BLM inhibitor, IC50=0.8 μM; hinders CRC cell growth, invasion, cycle arrest, and death.Formula:C33H38BrFN4OColore e forma:SolidPeso molecolare:605.58SIRT6 activator 12q
CAS:SIRT6 activator 12q: potent, selective, oral; IC50 - SIRT1: 171.20μM, SIRT6: 0.58μM; halts cell growth/migration, induces apoptosis, G2 arrest, anticancer.Formula:C31H22N2O2Colore e forma:SolidPeso molecolare:454.52CEP-1612
CAS:CEP-1612 inhibits protein breakdown, regulates cell cycles, apoptosis, boosts p21/p27 expression, and curbs lung cancer growth.Formula:C35H53N7O7Colore e forma:SolidPeso molecolare:683.84SKLB0565
CAS:SKLB0565 inhibits tubulin and colorectal cancer growth (IC50: 0.012-0.081 μM), causes G2/M arrest, triggers apoptosis, and prevents HUVEC migration.Formula:C20H25ClN6OColore e forma:SolidPeso molecolare:400.91MI-63
CAS:MI-63 is a potent, specific, non-peptide inhibitor of the MDM2-p53 interaction.Formula:C29H35Cl2FN4O3Colore e forma:SolidPeso molecolare:577.52Mcl1-IN-3
CAS:Mcl1-IN-3 is an Mcl1 inhibitor. It has an IC50 and Ki of 0.67 and 0.13 μM, respectively.Formula:C27H22ClN3O4Purezza:98%Colore e forma:SolidPeso molecolare:487.93RI-962
CAS:RI-962 is a potent and selective inhibitor of RIPK1 that protects cells from necrotic apoptosis by inhibiting RIPK1, RIPK3, and MLKL phosphorylation.Formula:C28H28N6O2Purezza:99.39%Colore e forma:SoildPeso molecolare:480.56NSC114792
CAS:NSC114792 is a selective JAK3 inhibitor.Formula:C26H32N4O2SPurezza:98%Colore e forma:SolidPeso molecolare:464.62CDK/HDAC-IN-2
CAS:CDK/HDAC-IN-2 inhibits HDAC1,2,3, CDK1,2, induces G2/M arrest, apoptosis, and shows anti-tumor effects.Formula:C25H20Cl2N6O3Colore e forma:SolidPeso molecolare:523.37GGTI-2154
CAS:GGTI-2154 is a potent, selective geranylgeranyltransferase I (GGTase I) inhibitor, boasting an IC50 of 21 nM and demonstrating over 200-fold selectivity againstFormula:C24H28N4O3Colore e forma:SolidPeso molecolare:420.5Bcl-2/Mcl-1-IN-3
CAS:Bcl-2/Mcl-1-IN-3 is a Bcl-2/Mcl-1 inhibitor that acts on Mcl-1 (Ki: 0.14 μM) and Bcl-2 (Ki: 0.23 μM) and can be used in cancer research.Formula:C27H26ClNO4Colore e forma:SolidPeso molecolare:463.95PI3Kδ-IN-11
CAS:PI3Kδ-IN-11 is a potent and selective PI3Kδ inhibitor (IC50: 27.5 nM) that dose-dependently blocks PI3K/Akt pathway activity.Formula:C27H21N5OColore e forma:SolidPeso molecolare:431.49PI3K-IN-33
CAS:PI3K-IN-33 selectively inhibits PI3K-α/β/δ, blocks G2/M, induces apoptosis, for leukemia research.Formula:C23H21BrN6O2Colore e forma:SolidPeso molecolare:493.36GSK-345931A
CAS:GSK-345931A, Potent oral RIP2 inhibitor, suppresses pro-inflammatory cytokines, for autoimmune disease studies.Formula:C22H19ClNNaO3Colore e forma:SolidPeso molecolare:403.83CZS-241
CZS-241: Oral PLK4 inhibitor (IC50=2.6 nM), less potent TRKA blocker (IC50=2.74 μM), triggers apoptosis and S/G2 arrest, anti-leukemia, safe for normal cells.Formula:C26H24ClF2N9OColore e forma:SolidPeso molecolare:551.98HDAC1/6-IN-1
CAS:HDAC1/6-IN-1, a dual HDAC1 (89 nM) and HDAC6 (13 nM) inhibitor, blocks cancer cell cycle, triggers apoptosis, and halts metastasis.Formula:C32H45N7O4Colore e forma:SolidPeso molecolare:591.74Metallo-β-lactamase-IN-5
CAS:Metallo-β-lactamase-IN-5 (compound 5c) is a powerful inhibitor of metallo-β-lactamases (MBLs).Formula:C19H16N4O3Colore e forma:SolidPeso molecolare:348.36Antiproliferative agent-11
Antiproliferative agent-11, a Ruthenium(II) complex, targets multiple cancers with IC50s of 6-10 μM.Formula:C31H34Cl2N6O3P2RuColore e forma:SolidPeso molecolare:772.56CGP 65015
CAS:CGP 65015 is an oral iron chelator and can mobilize iron deposits.Formula:C14H15NO4Purezza:98%Colore e forma:SolidPeso molecolare:261.27PHM16
CAS:PHM16 is an ATP competitive FAK and FGFR2 inhibitor.Formula:C20H22N6O4Purezza:98%Colore e forma:SolidPeso molecolare:410.43FKBP51F67V-selective antagonist Ligand2
CAS:FKBP51F67V-selective antagonist Ligand2 (example 3-3), a potent ligand, selectively binds to the FKBP51 F67V variant, with no affinity for wild-type FKBP51 orFormula:C43H56N2O10Purezza:98%Colore e forma:SolidPeso molecolare:760.91ARN 14494
CAS:ARN 14494, a potent SPT inhibitor (IC50=27.3 nM), reduces ceramide synthesis and neuroinflammation, and protects against β-amyloid toxicity.Formula:C24H32N4O3Colore e forma:SolidPeso molecolare:424.54Topoisomerase II inhibitor 11
CAS:Topoisomerase II inhibitor 11 (compound 3d) is a potent inhibitor of Topoisomerase II (IC50: 2.89 μM).Formula:C27H21BrCl2N2O2SColore e forma:SolidPeso molecolare:588.34RIPK1-IN-11
CAS:RIPK1-IN-11, an oral RIPK1 blocker, Kd 9.2 nM, IC50 67 nM, prevents necrosis and inflammation in cells.Formula:C23H24N4O4SColore e forma:SolidPeso molecolare:452.53DRAK1/2-IN-1
CAS:DRAK1/2-IN-1 is a potent inhibitor targeting both DRAK1 and DRAK2, displaying dissociation constants (Kd) of 1 µM and 6 µM, respectively.Formula:C22H24N2O3SColore e forma:SolidPeso molecolare:396.5Casein Kinase inhibitor A51
CAS:Casein Kinase inhibitor A51 is a CK1α inhibitor with anticancer activity used in the study of breast and prostate cancer.Formula:C18H25ClN6Purezza:98.42% - 99.88%Colore e forma:SolidPeso molecolare:360.88Ref: TM-T9175
2mg80,00€5mg117,00€1mL*10mM (DMSO)126,00€10mg172,00€25mg268,00€50mg413,00€100mg602,00€200mg1.018,00€PD-1/PD-L1-IN 5
CAS:PD-1/PD-L1-IN 5 is a potent PD-1/PD-L1 protein/protein interaction inhibitor (IC50 ≤ 100 nM).Formula:C22H18N4O3SColore e forma:SolidPeso molecolare:418.47Anticancer agent 58
Anticancer agent 58 targets A549/T24 cell lines; IC50: 0.6/0.7 μM. It triggers apoptosis, ups Ca2+/ROS, and lowers mitochondrial potential.Formula:C39H55NO5Colore e forma:SolidPeso molecolare:617.86hnRNPK-IN-1
CAS:hnRNPK-IN-1 binds hnRNPK tightly (Kd 4.6-2.6 μM), disrupting c-myc transcription and inducing apoptosis in Hela cells.Formula:C23H21N3O5Colore e forma:SolidPeso molecolare:419.43MRS 2693 trisodium salt
CAS:MRS 2693 trisodium salt is a P2Y6 agonist.Formula:C9H22IN5O12P2Purezza:98%Colore e forma:SolidPeso molecolare:581.15Luxeptinib
CAS:Luxeptinib (CG-806) is an oral, non-covalent pan-FLT3/BTK inhibitor for acute myeloid leukemia.Formula:C25H17F4N5O2Colore e forma:SolidPeso molecolare:495.43CDK6/PIM1-IN-1
CAS:CDK6/PIM1-IN-1: A dual inhibitor for CDK6 (39 nM IC50) & PIM1 (88 nM), also targets CDK4 (3.6 nM IC50), halts AML cell growth, and induces apoptosis.Formula:C25H28FN9Colore e forma:SolidPeso molecolare:473.55Verticillin A
CAS:Verticillin A, an apoptosis inducer, inhibits Leiomyosarcoma and Malignant peripheral nerve sheath tumor growth.Formula:C30H28N6O6S4Purezza:98%Colore e forma:SolidPeso molecolare:696.84SK-7041
CAS:SK-7041 is an effective HDAC inhibitor that acts by preferentially inhibiting class I HDAC1 and HDAC2.Formula:C19H21N3O3Purezza:98%Colore e forma:SolidPeso molecolare:339.39Gemcitabine monophosphate
CAS:R306465, a potent HDAC1/8 inhibitor, has broad antitumor effects (IC50: 30-300 nM) on solid and blood cancers.Formula:C9H12F2N3O7PColore e forma:SolidPeso molecolare:343.18VEGFR-2-IN-28
CAS:VEGFR-2-IN-28 is a potent inhibitor of VEGFR-2 (IC50: 0.83 μM). VEGFR-2-IN-28 induces apoptosis and exhibits antitumor effects.Formula:C26H17N7O7Colore e forma:SolidPeso molecolare:539.46VS 8
CAS:VS 8: potent oral VEGFR-2 inhibitor, anti-angiogenic, induces cancer cell apoptosis & migration, acts on CSCs.Formula:C26H20F3N3O3Colore e forma:SolidPeso molecolare:479.45MEK-IN-5
CAS:MEK-IN-5: strong MEK inhibitor and NO donor, reduces pMEK/pERK dose/time-dependently, triggers apoptosis in MDA-MB-231 cells.Formula:C29H27FN4O10S2Colore e forma:SolidPeso molecolare:674.67(R)-eIF4A3-IN-2
CAS:(R)-eIF4A3-IN-2, a weaker eIF4A3-IN-2 isomer, inhibits eIF4A3 selectively with 110 nM IC50.Formula:C25H19Br2ClN4O2Colore e forma:SolidPeso molecolare:602.71RGB-286147
CAS:RGB-286147 is a potent, selective, ATP-competitive Cdks inhibitor.Formula:C23H22Cl2N4O3Purezza:98%Colore e forma:SolidPeso molecolare:473.35OXPHOS-IN-1
CAS:OXPHOS-IN-1 inhibits oxidative phosphorylation; halts MIA PaCa-2 (IC50: 2.34 μM) and BxPC-3 cells growth (IC50: 13.82 μM).Formula:C19H29N3O6S2Colore e forma:SolidPeso molecolare:459.58Anticancer agent 67
CAS:Anticancer agent 67 is a ciprofloxacin analogue, an anticancer agent that induces apoptosis and increases sub-G1 cell populations in MCF-7 cells.Formula:C26H24F2N6O2S2Colore e forma:SolidPeso molecolare:554.63Quinidine Monosulfate
CAS:Quinidine Monosulfate: an oral antiarrhythmic, CYP450db inhibitor, K+ blocker (IC50 19.9 μM), used in malaria research.Formula:C40H50N4O8SColore e forma:SolidPeso molecolare:746.92Tubulin polymerization-IN-13
CAS:Compound 4f inhibits tubulin polymerization (IC50: 0.37 μM), induces apoptosis, and has notable anti-cancer properties.Formula:C20H21NO6Colore e forma:SolidPeso molecolare:371.38VRT-043198
CAS:VRT-043198, a VX-765 metabolite, is a potent ICE/caspase-1 inhibitor, crossing the blood-brain barrier with K i of 0.8/0.6 nM.Formula:C22H29ClN4O6Colore e forma:SolidPeso molecolare:480.94TNF-α-IN-1
CAS:TNF-α-IN-1 is a TNF-α inhibitor.Formula:C16H14ClN3O5Purezza:98.82%Colore e forma:SolidPeso molecolare:363.75Ref: TM-T13175
1mg56,00€5mg120,00€10mg178,00€1mL*10mM (DMSO)203,00€25mg330,00€50mg505,00€100mg713,00€2,3-DCPE
CAS:Induces p21, S-phase arrest in cancer cells through ERK pathways. IC50: 0.89 μM (LoVo cells), 12.6 μM (fibroblasts).Formula:C11H15Cl2NO2Purezza:98%Colore e forma:SolidPeso molecolare:264.15TL02-59 dihydrochloride
CAS:TL02-59 dihydrochloride is an orally active inhibitor of Src-family kinase Fgr (IC50: 0.03 nM).Formula:C32H36Cl2F3N5O4Purezza:98%Colore e forma:SolidPeso molecolare:682.56c-Met-IN-9
CAS:c-Met-IN-9 is a 4-phenoxypyridine derivative and a c-Met kinase inhibitor (IC50: 12 nM). c-Met-IN-9 induces apoptosis and shows antitumour effects.Formula:C25H19F2N5O3Colore e forma:SolidPeso molecolare:475.45Bozepinib
CAS:Bozepinib is an antitumor compound that acts by inducing PKR-mediated apoptosis and synergizing with IFN.Formula:C20H14Cl2N6O5SPurezza:98%Colore e forma:SolidPeso molecolare:521.33CMLD012072
CAS:CMLD012072 is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor with potent anti-neoplastic activity. It can induce RNA clamping of eIF4A1 and eIF4A2.Formula:C32H32N2O7Purezza:98%Colore e forma:SolidPeso molecolare:556.61AG6033
CAS:AG6033, a novel CRBN modulator, degrades GSPT1/IKZF1 and inhibits various tumors.Formula:C30H23N5O4Colore e forma:SolidPeso molecolare:517.53HDAC-IN-31
CAS:HDAC-IN-31: Oral HDAC inhibitor; targets HDAC1, 2, 3; weak on HDAC8; potential in fighting lymphoma.Formula:C25H24N4O2Colore e forma:SolidPeso molecolare:412.48PARP-1-IN-2
CAS:PARP-1-IN-2 is a potent PARP1 inhibitor that crosses the blood-brain barrier (IC50: 149 nM).PARP-1-IN-2 showed significant antiproliferative activity against
Formula:C22H15Cl2N3O2Purezza:98.82%Colore e forma:SolidPeso molecolare:424.28TNF-α-IN-18
CAS:TNF-α-IN-18 is a small molecule TNF-α inhibitor that blocks NF-κB translocation, alleviates sepsis in models, and protects against rheumatoid arthritis in mice.Formula:C16H7ClF2O4Purezza:99.77%Colore e forma:SolidPeso molecolare:336.67PD180970
CAS:PD180970 is an inhibitor of Bcr-Abl with IC50s of 5 nM, 0.8 nM and 50 nM for the autophosphorylation of p210Bcr-Abl, Src and Kit.Formula:C21H15Cl2FN4OPurezza:98.67%Colore e forma:SolidPeso molecolare:429.27Ref: TM-T23128
100mgPrezzo su richiesta5mg55,00€1mL*10mM (DMSO)60,00€10mg92,00€25mg137,00€50mg198,00€MI-389
CAS:MI-389 is a PROTAC degrader that induces the degradation of receptor tyrosine kinases (RTKs), useful for leukemia research.Formula:C35H35FN6O6Purezza:98.12%Colore e forma:SolidPeso molecolare:654.69Ref: TM-T33380
1mg88,00€5mg204,00€1mL*10mM (DMSO)276,00€10mg304,00€25mg476,00€50mg811,00€100mg1.401,00€EP12
CAS:EP12, a c-Myc inhibitor and G4 stabilizer, induces apoptosis and DNA damage in multiple myeloma cells while obstructing P65/P50 nuclear translocation byFormula:C26H22FN3O2Purezza:98%Colore e forma:SolidPeso molecolare:427.47Telomerase-IN-4
CAS:Telomerase-IN-4 is a potent inhibitor of telomerase with antiproliferative properties and induces apoptosis [1].Formula:C21H18N4OS2Purezza:98%Colore e forma:SolidPeso molecolare:406.52Anticancer agent 147
CAS:Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROSFormula:C32H40BrN3O2Purezza:98%Colore e forma:SolidPeso molecolare:578.58CRA-026440
CAS:CRA-026440(PCI-34051) is a highly potent HDAC inhibitor with inhibitory effects on HDAC1, HDAC2, HDAC3, HDAC6, HDAC8 and HDAC10 with Ki values of 4,14,11,15,7Formula:C23H24N4O4Purezza:96.42%Colore e forma:SolidPeso molecolare:420.46RIP1 kinase inhibitor 5
CAS:RIP1 kinase inhibitor 5 (example 1) serves as a potent regulator of tumor immunity by inhibiting RIP1, functioning similarly to SIR1-365 (compound 13) inFormula:C13H17F2NO2Purezza:98%Colore e forma:SolidPeso molecolare:257.28Tolbutamide Sodium
CAS:potassium channel blockerFormula:C12H18N2NaO3SPurezza:98%Colore e forma:SolidPeso molecolare:293.34HDAC-IN-36
CAS:HDAC-IN-36: Oral HDAC6 inhibitor, IC50 = 11.68 nM, promotes apoptosis & autophagy, anti-tumor & anti-metastatic, for breast cancer research.Formula:C29H39N5O5Colore e forma:SolidPeso molecolare:537.65CK2/ERK8-IN-1
CAS:TMCB inhibits CK2 (Ki: 0.25 µM), ERK8 (IC50: 0.50 µM), PIM1, DYRK1A, HIPK2 (Ki: 8.65-15.25 µM), and induces apoptosis.Formula:C11H9Br4N3O2Purezza:98.22%Colore e forma:SolidPeso molecolare:534.82(R)-STU104
CAS:(R)-STU104 is a TAK1-MKK3 protein-protein interaction (PPI) inhibitor. (R)-STU104 is a candidate compound for the treatment of ulcerative colitis.Formula:C18H18O4Purezza:98.91% - 99.42%Colore e forma:SolidPeso molecolare:298.33IMM-H004
CAS:IMM-H004 is an effective inhibitor of BV2 microglia activation.Formula:C16H20N2O4Purezza:98%Colore e forma:SolidPeso molecolare:304.34NKP-1339
CAS:NKP-1339 (IT-139) induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway.Formula:C14H12Cl4N4NaRuPurezza:98%Colore e forma:SolidPeso molecolare:502.14BTK-IN-24
CAS:BTK-IN-24 is a Bruton's tyrosine kinase (BTK) inhibitor with potential anticancer activity, and it can be used in the study of myeloproliferative disorders.Formula:C26H19F4N5O2Purezza:99.61%Colore e forma:SolidPeso molecolare:509.46RETRA
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