Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(1 prodotti)
- Caspasi(154 prodotti)
- FOXO1(2 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(127 prodotti)
- PDK(9 prodotti)
- PERK(23 prodotti)
- Chinasi di serina/treonina(17 prodotti)
- Survivin(14 prodotti)
- TNF(90 prodotti)
- c-RET(61 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 6170 prodotti di "Apoptosi"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
DBIBB
CAS:DBIBB: non-lipid LPA2 receptor agonist, treats acute radiation syndrome, aids in organic synthesis/drug research.Formula:C23H20N2O6SPurezza:98.49% - 99.1%Colore e forma:SolidPeso molecolare:452.48Ref: TM-T22070
1mg42,00€5mg93,00€10mg134,00€25mg264,00€50mg378,00€100mg553,00€500mg1.111,00€1mL*10mM (DMSO)93,00€DMH2
CAS:DMH2 is an antagonist of bone morphogenetic protein (BMP) type I receptor. It acts by decreasing growth and inducing cell death of lung cancer cell lines.Formula:C27H25N5O2Purezza:98%Colore e forma:SolidPeso molecolare:451.52PDGFR-IN-1
CAS:PDGFR-IN-1 is a platelet-derived growth factor receptor (PDGFR) inhibitor, strongly inhibiting PDGFRα and PDGFRβ, useful for studying solid tumors.Formula:C25H30N8OPurezza:99.13% - 99.49%Colore e forma:SolidPeso molecolare:458.56Ref: TM-T62872
1mg170,00€5mg432,00€10mg655,00€25mg1.153,00€50mg1.665,00€100mg2.250,00€1mL*10mM (DMSO)434,00€CAY10443
CAS:CAY10443 activates apoptosis by binding to apoptosome components, with an EC50 of 5 μM for caspase-3, aiding antitumor drug development.Formula:C17H15Cl2NO2Colore e forma:SolidPeso molecolare:336.21TRK-IN-23
CAS:TRK-IN-23 (compound 24b) is a potent, orally active inhibitor of TRK with IC50s of 0.5 nM for TRKA, 9 nM for TRKC, 14 nM for TRKA G595R, 4.4 nM for TRKA F589L,Formula:C20H17FN4O2Purezza:98%Colore e forma:SolidPeso molecolare:364.37BLM-IN-2
BLM-IN-2: BLM inhibitor, IC50=0.8 μM; hinders CRC cell growth, invasion, cycle arrest, and death.Formula:C33H38BrFN4OColore e forma:SolidPeso molecolare:605.58SIRT6 activator 12q
CAS:SIRT6 activator 12q: potent, selective, oral; IC50 - SIRT1: 171.20μM, SIRT6: 0.58μM; halts cell growth/migration, induces apoptosis, G2 arrest, anticancer.Formula:C31H22N2O2Colore e forma:SolidPeso molecolare:454.52CEP-1612
CAS:CEP-1612 inhibits protein breakdown, regulates cell cycles, apoptosis, boosts p21/p27 expression, and curbs lung cancer growth.Formula:C35H53N7O7Colore e forma:SolidPeso molecolare:683.84SKLB0565
CAS:SKLB0565 inhibits tubulin and colorectal cancer growth (IC50: 0.012-0.081 μM), causes G2/M arrest, triggers apoptosis, and prevents HUVEC migration.Formula:C20H25ClN6OColore e forma:SolidPeso molecolare:400.91ABI-231 HCl
CAS:ABI-231: Oral tubulin inhibitor, IC50=5.2 nM for melanoma/prostate cancer, in clinical trials for prostate cancer, effective in vivo.Formula:C21H20ClN3O4Colore e forma:SolidPeso molecolare:413.85Anticancer agent 72
CAS:Compound 8c inhibits K+ channel and induces apoptosis, showing promise as an anticancer agent.Formula:C20H19N7O2Colore e forma:SolidPeso molecolare:389.41MI-63
CAS:MI-63 is a potent, specific, non-peptide inhibitor of the MDM2-p53 interaction.Formula:C29H35Cl2FN4O3Colore e forma:SolidPeso molecolare:577.52p-nitro-Pifithrin-α
CAS:p-nitro-Pifithrin-α is a cell-permeable analog of pifithrin-α, a potent p53 inhibitor.Formula:C15H16BrN3O3SColore e forma:SolidPeso molecolare:398.27S-Gem
CAS:S-Gem, a thioredoxin reductase (TrxR)-dependent prodrug of Gemcitabine, is selectively activated by TrxR.Formula:C13H15F2N3O6S2Purezza:98%Colore e forma:SolidPeso molecolare:411.4Antiproliferative agent-7
CAS:Antiproliferative agent-7 (compound 8f) is a potent anti-proliferative agent. Antiproliferative agent-7 can promote ROS production and induce apoptosis.Formula:C28H32N4OColore e forma:SolidPeso molecolare:440.58Mcl1-IN-3
CAS:Mcl1-IN-3 is an Mcl1 inhibitor. It has an IC50 and Ki of 0.67 and 0.13 μM, respectively.Formula:C27H22ClN3O4Purezza:98%Colore e forma:SolidPeso molecolare:487.93RO27-3225 TFA
CAS:RO27-3225, a MC4R agonist (EC50=1nM), may treat obesity and brain damage, also acts on MC1R, and helps in hemorrhagic shock.Formula:C41H53F3N12O8Colore e forma:SolidPeso molecolare:898.9462CRA-026440
CAS:CRA-026440(PCI-34051) is a highly potent HDAC inhibitor with inhibitory effects on HDAC1, HDAC2, HDAC3, HDAC6, HDAC8 and HDAC10 with Ki values of 4,14,11,15,7Formula:C23H24N4O4Purezza:96.42%Colore e forma:SolidPeso molecolare:420.46DB2313 HCl
CAS:DB2313: first-in-class, potent inhibitor of PU.1, disrupts gene interactions, down-regulates PU.1 targets.Formula:C42H45Cl4FN8O2Colore e forma:SolidPeso molecolare:854.67Mcl1-IN-4
CAS:Mcl1-IN-4 is an inhibitor of Mcl1 ( IC50:0.2 μM).Formula:C28H26N2O5SPurezza:98%Colore e forma:SolidPeso molecolare:502.58p-MPPF dihydrochloride
CAS:p-MPPF dihydrochloride is a 5-HT antagonist that can be used to study neurological diseases.Formula:C25H29Cl2FN4O2Purezza:99.55%Colore e forma:SolidPeso molecolare:507.43CHS-828 nicotinate
CAS:CHS-828, or GMX-1778, is a potent NAMPT inhibitor with anticancer properties, active against tumors and enhanced by certain drugs.Formula:C25H27ClN6O3Colore e forma:SolidPeso molecolare:494.97Didesmethylrocaglamide
CAS:Didesmethylrocaglamide, a Rocaglamide derivative, is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor that exhibits strong growth-inhibitory effects,Formula:C27H27NO7Colore e forma:SolidPeso molecolare:477.51NSC114792
CAS:NSC114792 is a selective JAK3 inhibitor.Formula:C26H32N4O2SPurezza:98%Colore e forma:SolidPeso molecolare:464.62TACC3 inhibitor 1
Potent TACC3 inhibitor 1 crosses the blood-brain barrier, induces apoptosis, G2/M arrest, ROS, and has anti-tumor effects.Formula:C20H21N5OSColore e forma:SolidPeso molecolare:379.48Nanatinostat TFA
CAS:Nanatinostat (Tractinostat, CHR-3996, VRx-3996) is a second-gen oral HDAC inhibitor with potential cancer treatment properties.Formula:C22H20F4N6O4Colore e forma:SolidPeso molecolare:508.43Semapimod
CAS:Semapimod is an inhibitor of proinflammatory cytokine production, capable of suppressing TNF-α, IL-1β, and IL-6.Formula:C34H52N18O2Colore e forma:SolidPeso molecolare:744.9PQ1 Succinate
CAS:PQ1 Succinate boosts GJIC and connexin in breast cancer cells without impacting normal mammary cells.Formula:C25H28F3N3O6Colore e forma:SolidPeso molecolare:523.5CDK/HDAC-IN-2
CAS:CDK/HDAC-IN-2 inhibits HDAC1,2,3, CDK1,2, induces G2/M arrest, apoptosis, and shows anti-tumor effects.Formula:C25H20Cl2N6O3Colore e forma:SolidPeso molecolare:523.37DC-CPin711
CAS:DC-CPin711: Potent, selective CBP bromodomain inhibitor, IC50=0.0626 μM; arrests G1 cell cycle, induces apoptosis.Formula:C23H22N4O2Colore e forma:SolidPeso molecolare:386.45IM-93
CAS:IM-93 inhibits ferroptosis and NETosis with an IC< sub>50 of 0.45 μM for cell death inhibition [1].Formula:C21H28N4O2Colore e forma:SolidPeso molecolare:368.47Anti-inflammatory agent 22
CAS:Compound 14a is an oral anti-inflammatory with an IC50 of 14.6 μM for TNF-α, preventing adipogenesis and reducing mouse limb lymphedema.Formula:C22H16O6Colore e forma:SolidPeso molecolare:376.36R-547 mesylate
CAS:R547 Mesylate is a potent ATP-competitive inhibitor of CDK1, CDK2, CDK4 with Ki value of 2 nM, 3 nM, 1 nM respectively.Formula:C19H25F2N5O7S2Colore e forma:SolidPeso molecolare:537.56VO-OHPic
CAS:VO-OHPic, a selective PTEN inhibitor (IC50 = 46 nM), reduces apoptosis and inflammation in doxorubicin-induced cardiomyopathy.Formula:C12H10N2O8VColore e forma:SolidPeso molecolare:361.16SCFSkp2-IN-2
CAS:SCFSkp2-IN-2, a Skp2 inhibitor, exhibits a dissociation constant (K_D) of 28.77 μM.
Formula:C17H20N4O2Purezza:99.86%Colore e forma:SolidPeso molecolare:312.37UCB-5307
CAS:UCB-5307 inhibits TNFR1, binds TNFα with 9 nM KD, shows slow kinetics (KD=6 nM), and penetrates hTNF/hTNFR1 complexes.Formula:C22H21N3OPurezza:98.76%Colore e forma:SolidPeso molecolare:343.42Vamotinib
CAS:Vamotinib (PF-114) is a tyrosine kinase inhibitor with antiproliferative and antitumor activity.Vamotinib is used in the study of Alzheimer's disease.Formula:C29H27F3N6OPurezza:99.64%Colore e forma:SolidPeso molecolare:532.56Ref: TM-T63746
1mg101,00€5mg245,00€10mg401,00€25mg717,00€50mg982,00€100mg1.341,00€200mg1.783,00€1mL*10mM (DMSO)288,00€PARP/PI3K-IN-1
CAS:PARP/PI3K-IN-1 is a PARP and PI3K dual inhibitor with anticancer and antiproliferative activities for the study of breast, pancreatic and lung cancers.Formula:C33H28F4N8O3Purezza:99.59%Colore e forma:SolidPeso molecolare:660.62SYM 2081
CAS:SYM 2081: Kainate receptor agonist, IC50 of 35 nM, depolarizes muscle, lowers EPSP amplitude.Formula:C6H11NO4Purezza:99.63%Colore e forma:SolidPeso molecolare:161.16(S)-Enitociclib
CAS:(S)-Enitociclib (VIP152) is a selective CDK9 inhibitor that inhibits the transcription of anti-apoptotic and pro-survival proteins.Formula:C19H18F2N4O2SPurezza:98.98%Colore e forma:SolidPeso molecolare:404.43STAT3-IN-13
CAS:STAT3-IN-13 is a STAT3 inhibitor with antiproliferative activity that induces apoptosis and can be used to study breast and liver cancer.Formula:C21H20N6O3SPurezza:98.89%Colore e forma:SolidPeso molecolare:436.49SB 699551 dihydrochloride
CAS:SB 699551 dihydrochloride is a 5-ht5a receptor antagonist.Formula:C34H47Cl2N3OPurezza:99.83%Colore e forma:SolidPeso molecolare:584.66Ref: TM-T23325
1mg50,00€5mg105,00€10mg170,00€25mg295,00€50mg424,00€100mg583,00€1mL*10mM (DMSO)142,00€MK-28
CAS:MK-28 is a PERK agonist that reduces toxicity in a Huntington's disease model.MK-28 has a significant killing effect on MK28 gastric cancer cells.Formula:C24H20N4O2Colore e forma:SolidPeso molecolare:396.44Ref: TM-T61859
1mg94,00€5mg222,00€10mg356,00€25mg690,00€50mg1.044,00€100mg1.558,00€1mL*10mM (DMSO)245,00€LQZ-7F
CAS:LQZ-7F is a survivin dimerization inhibitor with anticancer activity.LQZ-7F induces proteasome-dependent survivin degradation and inhibits human tumor growth.Formula:C14H7N9O3Purezza:98.64%Colore e forma:SolidPeso molecolare:349.26CMLD-2
CAS:CMLD-2 is a HuR-ARE inhibitor (Ki: 350 nM) that promotes apoptosis, has antitumor properties, and reduces thyroid cancer cell viability.Formula:C31H31NO6Purezza:99.99%Colore e forma:SolidPeso molecolare:513.58Ref: TM-T36493
1mg92,00€5mg222,00€10mg371,00€25mg608,00€50mg848,00€100mg1.144,00€500mg2.277,00€1mL*10mM (DMSO)245,00€SLMP53-1
CAS:SLMP53-1 is a p53 activator with anti-tumor activity, activates reprogramming of glucose metabolism, and interferes with angiogenesis and migrationFormula:C20H18N2O2Purezza:99.64%Colore e forma:SolidPeso molecolare:318.37Ref: TM-T60839
1mg119,00€5mg281,00€10mg462,00€25mg888,00€50mg1.485,00€100mg2.385,00€1mL*10mM (DMSO)34,00€iCRT-5
CAS:iCRT-5 is a potent inhibitor of the Wnt pathway. iCRT-5 has antiproliferative activity and can be used in the study of multiple myeloma.Formula:C16H17NO5S2Purezza:99.68%Colore e forma:SolidPeso molecolare:367.44Brigimadlin
CAS:Brigimadlin (BI 907828) is an orally active and highly potent antagonist of the E3 ubiquitin-protein ligase MDM2-p53 with antitumor activity.Formula:C31H25Cl2FN4O3Purezza:98.17%Colore e forma:SolidPeso molecolare:591.46Ref: TM-T69923
1mg150,00€5mg258,00€10mg353,00€25mg578,00€50mg879,00€100mg1.314,00€1mL*10mM (DMSO)335,00€AQ4
CAS:AQ4 is a topoisomerase II inhibitor and DNA-inserting agent that inhibits proliferation and induces apoptosis in two cell lines.Formula:C22H28N4O4Purezza:96.28% - 97.15%Colore e forma:SolidPeso molecolare:412.48DCG066
CAS:DCG066 is an inhibitor of lysine methyltransferase G9a with anticancer activity and may be used in the study of leukemia.Formula:C30H31F6N3O2Purezza:98.26% - 98.38%Colore e forma:SolidPeso molecolare:579.58Ref: TM-T27132
1mg215,00€5mg537,00€10mg730,00€25mg1.134,00€50mg1.468,00€100mg1.863,00€200mg2.512,00€1mL*10mM (DMSO)685,00€RET-IN-23
CAS:RET-IN-23 is an orally available and highly potent RET inhibitor with significant antitumor activity for the study of non-small cell lung cancer.Formula:C28H28FN11Purezza:97.46%Colore e forma:SolidPeso molecolare:537.59T025
CAS:T025 inhibits CLK1-4 (Kds: 0.074-6.5 nM), shows anti-cancer effects (IC50: 30-300 nM), useful for MYC-related disease research.Formula:C21H18N8Purezza:99.20%Colore e forma:SolidPeso molecolare:382.42Ref: TM-T13058
1mg136,00€5mg334,00€10mg500,00€25mg807,00€50mg1.099,00€100mg1.485,00€500mg2.962,00€1mL*10mM (DMSO)358,00€UNC0321
CAS:UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays.Formula:C27H45N7O3Purezza:99.80%Colore e forma:SolidPeso molecolare:515.69Benitrobenrazide
CAS:Benitrobenrazide (Hexokinase 2 inhibitor 1) is a novel orally available hexokinase 2 (HK2) inhibitor with anticancer and antitumor activity for cancer research.Formula:C14H11N3O6Purezza:96.87%Colore e forma:SolidPeso molecolare:317.25H2L5186303
CAS:H2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment.Formula:C26H20N2O8Purezza:98.19%Colore e forma:SolidPeso molecolare:488.45Ref: TM-T22835
2mg44,00€5mg64,00€10mg94,00€25mg180,00€50mg283,00€100mg465,00€200mg642,00€1mL*10mM (DMSO)75,00€MMRi64
CAS:MMRi64 inhibits Mdm2-MdmX, boosts p53, triggers apoptosis, and is used in cancer research.Formula:C22H17Cl2N3OPurezza:99.93%Colore e forma:SolidPeso molecolare:410.3Alethine
CAS:Alethine is a small antitumor compound used to treat cancers and infections, boosting T-cell cytotoxicity by raising TNFα.Formula:C10H22N4O2S2Purezza:99.78%Colore e forma:SolidPeso molecolare:294.44NM-3
CAS:NM-3, an oral anti-angiogenic and anti-tumor agent, modulates radiation and blocks VEGF to curb endothelial growth and induce apoptosis.Formula:C13H12O6Purezza:99.89%Colore e forma:SolidPeso molecolare:264.23Ref: TM-T33701
1mg172,00€5mg432,00€10mg618,00€25mg973,00€50mg1.333,00€100mg1.791,00€500mg3.529,00€1mL*10mM (DMSO)394,00€Deferitazole
CAS:Deferitazole (FBS 0701) is a novel and orally active, selective and high affinity iron chelator.Formula:C18H25NO7SPurezza:99.48%Colore e forma:SolidPeso molecolare:399.46Antifolate C2
CAS:Antifolate C2 (AGF 154) inhibits tumor growth with 0.14 nM IC, useful in cancer/autoimmune research.Formula:C19H21N5O6SPurezza:99.57%Colore e forma:SolidPeso molecolare:447.46DX3-213B
CAS:DX3-213B is a potent, orally active inhibitor of oxidative phosphorylation (OXPHOS) complex I with an IC50 of 3.6 nM.Formula:C20H28F2N2O5S2Purezza:99.85%Colore e forma:SolidPeso molecolare:478.57Ref: TM-T63136
1mg81,00€5mg170,00€10mg274,00€25mg588,00€50mg852,00€100mg1.159,00€1mL*10mM (DMSO)180,00€AOH1160
CAS:AOH1160 is an inhibitor of proliferating cell nuclear antigen (PCNA).Formula:C25H20N2O3Purezza:98.46% - 99.52%Colore e forma:SolidPeso molecolare:396.44Sabizabulin
CAS:Sabizabulin (ABI-231) is a potent, orally bioavailable α- and β-tubulin inhibitor.Cost-effective and quality-assured.Formula:C21H19N3O4Purezza:98.10% - 99.79%Colore e forma:SolidPeso molecolare:377.39Ref: TM-T17228
1mg75,00€2mg99,00€5mg164,00€10mg255,00€25mg487,00€50mg803,00€100mg1.324,00€200mg1.783,00€HTH-01-091
CAS:HTH-01-091 is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor (IC50: 10.5 nM).HTH-01-091 inhibits PIM1/2/3, RIPK2, DYRK3,Formula:C26H28Cl2N4O2Purezza:98.82%Colore e forma:SolidPeso molecolare:499.43Ref: TM-T24152
1mg281,00€5mg692,00€10mg938,00€25mg1.454,00€50mg1.882,00€100mg2.375,00€1mL*10mM (DMSO)775,00€K-8012
CAS:K-8012 is a modulator of the N-terminally truncated RXRα and improves anticancer activities in an RXRα-dependent manner.Formula:C23H23FN4Purezza:99.72%Colore e forma:SolidPeso molecolare:374.45Ref: TM-T24240
1mg109,00€5mg241,00€10mg355,00€25mg532,00€50mg745,00€100mg1.018,00€500mg2.043,00€1mL*10mM (DMSO)253,00€Cot inhibitor-1
CAS:Cot inhibitor-1 selectively blocks Tpl2 kinase, reducing TNF-alpha in blood (IC50: 5.7 nM). It may treat arthritis, IBD, and certain cancers.Formula:C27H27Cl2FN8Purezza:98.87%Colore e forma:SolidPeso molecolare:553.46Ref: TM-T10865
1mg73,00€5mg152,00€10mg222,00€25mg401,00€50mg602,00€100mg887,00€200mg1.215,00€1mL*10mM (DMSO)177,00€MBM-55
CAS:MBM-55 is an effective inhibitor of NIMA related kinase 2 (NEK2) with an IC50 of 1 nM.Formula:C28H27FN6O2Purezza:99.83%Colore e forma:SolidPeso molecolare:498.55Ref: TM-T11960
1mg168,00€5mg281,00€10mg409,00€25mg627,00€50mg822,00€100mg1.108,00€500mg2.242,00€1mL*10mM (DMSO)309,00€BCP-T.A
CAS:BCP-T.A is an iron death inducer that acts by binding to GPX4.Formula:C23H19Cl2N3OSPurezza:99.49%Colore e forma:SolidPeso molecolare:456.39HS38
CAS:HS38: DAPK-specific ATP-competitive inhibitor; Kds: DAPK1 (300 nM), PIM3 (200 nM), ZIPK (280 nM); useful in smooth muscle disorder research.Formula:C14H12ClN5O2SPurezza:98.19%Colore e forma:SolidPeso molecolare:349.8GSK2593074A
CAS:GSK2593074A (GSK'074) is a programmed necrosis inhibitor that displays inhibitory effects on RIP1 and RIP3.Formula:C27H23N5OSPurezza:99.99%Colore e forma:SolidPeso molecolare:465.57Ref: TM-T11484
1mg108,00€5mg260,00€10mg409,00€25mg687,00€50mg964,00€100mg1.288,00€1mL*10mM (DMSO)286,00€TNIK-IN-3
CAS:TNIK-IN-3 is a highly potent and orally active inhibitor of Traf2- and Nck-interacting protein kinase (TNIK).Formula:C23H18FN3O2Purezza:98.39%Colore e forma:SolidPeso molecolare:387.41Atrosab
CAS:Atrosab is a humanized IgG1 antibody targeting TNFR1, inhibiting TNF-mediated apoptosis, and can be used to study inflammatory and neurodegenerative diseases.Purezza:95.22% (SEC-HPLC) - >95.0% (SDS-PAGE); 95.68% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:146.12 kDaBCL6-IN-7
CAS:BCL6-IN-7 (BCL6 inhibitor-7) is a BCL6 corepressor-interaction inhibitor with potential antitumor activity, used in lymphoma research.Formula:C18H15ClN6OPurezza:99.03%Colore e forma:SolidPeso molecolare:366.8CTA 056
CAS:CTA 056 is an ITK inhibitor that inhibits the growth of MOLT-4 xenograft tumors in mice and can be used to study autoimmune disorders.Formula:C35H34N6OPurezza:97.22% - 97.76%Colore e forma:SolidPeso molecolare:554.68Pyrazoloacridine
CAS:Pyrazoloacridine (PD 115934) binds DNA, inhibits topo I/II, has 1.25 μM IC50 in K562 cells, and exhibits anti-cancer effects.Formula:C19H21N5O3Purezza:99.72%Colore e forma:SolidPeso molecolare:367.4CDK9-IN-7
CAS:CDK9-IN-7: selective, oral CDK9/cyclin T inhibitor with 11 nM IC50, stronger than CDK4/6.Formula:C29H37N7O2SPurezza:98.08%Colore e forma:SolidPeso molecolare:547.71Ref: TM-T10745
1mg90,00€5mg208,00€10mg304,00€25mg457,00€50mg630,00€100mg845,00€200mg1.121,00€1mL*10mM (DMSO)229,00€UC-112
CAS:UC-112 is a novel potent IAP inhibitor and potently inhibits cell growth in two human melanoma and two human prostate cancer cell lines (IC50=0.7-3.4 uM).Formula:C22H24N2O2Purezza:99.54%Colore e forma:SolidPeso molecolare:348.44Ref: TM-T17195
1mg34,00€2mg44,00€5mg70,00€10mg99,00€25mg202,00€50mg311,00€100mg445,00€500mgPrezzo su richiesta1mL*10mM (DMSO)78,00€Miclxin
CAS:Miclxin (DS37262926) is a novel MIC60 inhibitor that induces apoptosis through mitochondrial stress in mutant tumor cells via β-catenin.Miclxin is a potentFormula:C26H27N5O2Purezza:99.17% - 99.99%Colore e forma:SolidPeso molecolare:441.52Ref: TM-T73415
1mg60,00€5mg133,00€10mg182,00€25mg306,00€50mg427,00€100mg587,00€200mg792,00€1mL*10mM (DMSO)147,00€MJN68390
CAS:MJN68390 has an apparent IC50 value of 15 μM against CASP8 and shows no activity against CASP10.Formula:C24H28ClN3O3Purezza:98.86%Colore e forma:SolidPeso molecolare:441.95D609
CAS:D609 (Tricyclodecan-9-yl-Xanthogenate) has antiviral and antiproliferative activities.D609 acts through competitive inhibition of PC, PC-P and SMS.Formula:C11H15KOS2Purezza:97.67% - 99.56%Colore e forma:Off-White PowderPeso molecolare:266.46Mitazalimab
CAS:Mitazalimab (ADC-1013/JNJ-64457107) is a CD40 agonist that stimulates T cells to attack tumors and remodels the tumor microenvironment.Purezza:95.1% (SDS-PAGE); 98.7% (SEC-HPLC) - 95.1% (SDS-PAGE); 98.7% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:143.42 kDaNecrostatin-5
CAS:Necrostatin-5 (Nec-5) inhibits RIP1 kinase, prevents cell necrosis, and protects Fadd-deficient Jurkat cells with an EC50 of 240 nM.Formula:C19H17N3O2S2Purezza:99.40%Colore e forma:SolidPeso molecolare:383.49Droloxifene
CAS:Droloxifene, a tamoxifen derivative and oral SERM, induces p53 and apoptosis; Fluroxifene protects bone, blocks estrogen and implantation.Formula:C26H29NO2Purezza:99.86% - 99.97%Colore e forma:Solid PowderPeso molecolare:387.51Ref: TM-T11098
1mg51,00€5mg110,00€10mg166,00€25mg268,00€50mg396,00€100mg532,00€500mgPrezzo su richiesta1mL*10mM (DMSO)126,00€ZDLD20
CAS:ZDLD20 is a CDK4 inhibitor with anti-HCT116 and anticancer activity that inhibits colony formation and blocks the G1 phase of the cell cycle.Formula:C22H22N6OPurezza:98.59%Colore e forma:SolidPeso molecolare:386.45Erastin2
CAS:Erastin2 is an iron death inducer that induces cell death by binding to the lipophilic free radical trapping antioxidant ferrostatin-1 or the iron chelator DFO.
Formula:C36H35ClN4O4Purezza:99.63%Colore e forma:SolidPeso molecolare:623.14NLRP3/AIM2-IN-3
CAS:NLRP3/AIM2-IN-3 selectively blocks NLRP3/AIM2 inflammasomes; IC50 for cell lysis is 0.077 μM, disrupting ASC oligomerization.Formula:C16H14N2O2Purezza:97.04%Colore e forma:SolidPeso molecolare:266.29Ref: TM-T60442
5mg71,00€10mg102,00€25mg205,00€50mg334,00€100mg537,00€500mg1.134,00€1mL*10mM (DMSO)78,00€EB1
CAS:EB1 is an MNK kinase inhibitor that inhibits cancer cell growth, promotes apoptosis, and inhibits eIF4E phosphorylation.Formula:C18H14N4Purezza:99.82%Colore e forma:SolidPeso molecolare:286.33Ref: TM-T73582
1g3.142,00€1mg71,00€5mg152,00€10mg215,00€25mg355,00€50mg533,00€100mg762,00€500mg2.115,00€AMG PERK 44
CAS:AMG PERK 44 is a PERK inhibitor that induces autophagy.AMG PERK 44 inhibits GCN2 and B-Raf and can be used in cancer research.Formula:C34H29ClN4O2Purezza:98.8% - 99.81%Colore e forma:SolidPeso molecolare:561.07FA16
FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16Formula:C22H27F3N4O2SPurezza:99.44%Colore e forma:SolidPeso molecolare:468.54Mepazine
CAS:Mepazine, a MALT1 inhibitor, blocks GSTMALT1 (IC50: 0.83μM) and GSTMALT1 325-760 (IC50: 0.42μM), promoting apoptosis and reducing cell viability.Formula:C19H22N2SPurezza:99.88% - 99.92%Colore e forma:SolidPeso molecolare:310.46Ref: TM-T16040
10mg39,00€25mg60,00€50mg93,00€100mg116,00€200mg177,00€500mgPrezzo su richiesta1mL*10mM (DMSO)35,00€HS-276
CAS:HS-276, a selective oral TAK1 inhibitor (Ki: 2.5 nM), also targets CLK2, GCK, ULK2, MAP4K5; potential for RA research.Formula:C24H29N5O2Purezza:97.67% - 98.81%Colore e forma:SolidPeso molecolare:419.52Ref: TM-T62209
1mg63,00€5mg137,00€10mg207,00€25mg408,00€50mg655,00€100mg1.009,00€200mg1.359,00€1mL*10mM (DMSO)161,00€VAS 3947
CAS:VAS 3947: NOX inhibitor, induces platelet apoptosis via UPR, not linked to NOX inhibition.Formula:C14H10N6OSPurezza:99.25%Colore e forma:SolidPeso molecolare:310.33Ref: TM-T29097
1mg46,00€5mg92,00€10mg166,00€25mg279,00€50mg403,00€100mg532,00€200mg705,00€1mL*10mM (DMSO)100,00€GCN2-IN-1
CAS:GCN2-IN-1 (A-92) is an effective GCN2 inhibitor and can be used in research on the treatment of cancer as a chemotherapeutic agent.
Formula:C19H18N10OPurezza:99.49% - 99.64%Colore e forma:SolidPeso molecolare:402.41Tiomolibdate diammonium
CAS:Tiomolibdate diammonium (NSC-286644) blocks SOD1 and COX, acting as an antiangiogenic and antitumor agent.Formula:H8MoN2S4Purezza:98%Colore e forma:Brown To Black Iridescent Crystalline PowderPeso molecolare:260.28p53-MDM2-IN-1
CAS:p53-MDM2-IN-1 (Example 30), an inhibitor targeting the p53-MDM2/X protein interaction, exhibits a K i value of 23.35 µM.Formula:C23H20ClN3O3Purezza:99.98%Colore e forma:SoildPeso molecolare:421.88LCS3
CAS:LCS3 is a reversible and non-competitive synergistic inhibitor of glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) with IC50s of 3.3Formula:C11H7ClN2O4Purezza:99.84%Colore e forma:SolidPeso molecolare:266.64Imipramine
CAS:Imipramine (Dimipressin) is a Fascin1 inhibitor with antitumor activity and induces apoptosis.Formula:C19H24N2Purezza:99.4%Colore e forma:White To Off-White /Hydrochloride/ SolidPeso molecolare:280.41Ro24-7429
CAS:Ro24-7429: oral HIV-1 Tat antagonist, RUNX1 inhibitor with anti-HIV, antifibrotic, and anti-inflammatory properties.Formula:C14H13ClN4Purezza:99.29% - 99.85%Colore e forma:SolidPeso molecolare:272.73Ref: TM-T28578
1mg87,00€5mg177,00€10mg281,00€25mg480,00€50mg692,00€100mg973,00€500mg2.725,00€1mL*10mM (DMSO)203,00€Bomedemstat ditosylate
CAS:Bomedemstat (IMG-7289) is an LSD1 inhibitor for acute myeloid leukemia, MDS, and Myelofibrosis; induces apoptosis by regulating p53, PUMA, and BCLXL.Formula:C42H50FN7O8S2Purezza:99.05%Colore e forma:SolidPeso molecolare:864.02Ref: TM-T70008
1mg84,00€5mg177,00€10mg264,00€25mg444,00€50mg640,00€100mg893,00€1mL*10mM (DMSO)250,00€R306465
CAS:R306465 (JNJ-16241199) is an HDAC 1 inhibitor with broad-spectrum anti-tumor activity, inducing apoptosis, and can be used to study solid tumors.Formula:C19H19N5O4SPurezza:98.46% - 99.54%Colore e forma:SolidPeso molecolare:413.45
