Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(1 prodotti)
- Caspasi(154 prodotti)
- FOXO1(2 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(127 prodotti)
- PDK(9 prodotti)
- PERK(23 prodotti)
- Chinasi di serina/treonina(17 prodotti)
- Survivin(14 prodotti)
- TNF(90 prodotti)
- c-RET(61 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 6170 prodotti di "Apoptosi"
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K-8012
CAS:K-8012 is a modulator of the N-terminally truncated RXRα and improves anticancer activities in an RXRα-dependent manner.Formula:C23H23FN4Purezza:99.72%Colore e forma:SolidPeso molecolare:374.45Ref: TM-T24240
1mg109,00€5mg241,00€1mL*10mM (DMSO)253,00€10mg355,00€25mg532,00€50mg745,00€100mg1.018,00€500mg2.043,00€Imipramine
CAS:Imipramine (Dimipressin) is a Fascin1 inhibitor with antitumor activity and induces apoptosis.Formula:C19H24N2Purezza:99.4%Colore e forma:White To Off-White /Hydrochloride/ SolidPeso molecolare:280.41RET-IN-23
CAS:RET-IN-23 is an orally available and highly potent RET inhibitor with significant antitumor activity for the study of non-small cell lung cancer.Formula:C28H28FN11Purezza:97.46%Colore e forma:SolidPeso molecolare:537.59GSK854
CAS:GSK854 is a selective TNNI3K inhibitor reducing heart damage and stress post-infarction in mice.Formula:C18H19ClN6O4S2Purezza:98.91%Colore e forma:SolidPeso molecolare:482.96Ref: TM-T24115
1mg92,00€5mg222,00€1mL*10mM (DMSO)245,00€10mg358,00€25mg710,00€50mg1.063,00€100mg1.684,00€500mg3.375,00€Epristeride
CAS:Epristeride (ONO-9302) is a steroidal 5-alpha-reductase isoform 2 inhibitor that inhibits SR isoform 2. Epristeride reduces prostate size.Formula:C25H37NO3Purezza:98.12% - >99.99%Colore e forma:SolidPeso molecolare:399.57GSK2983559 free acid
CAS:GSK2983559 free acid selectively inhibits RIP2, reducing inflammatory cytokines in human bowel disease.Formula:C21H23N4O7PS2Purezza:97.8700% - 99.56%Colore e forma:SolidPeso molecolare:538.53EB1
CAS:EB1 is an MNK kinase inhibitor that inhibits cancer cell growth, promotes apoptosis, and inhibits eIF4E phosphorylation.Formula:C18H14N4Purezza:99.82%Colore e forma:SolidPeso molecolare:286.33Ref: TM-T73582
1mg71,00€5mg152,00€10mg215,00€25mg355,00€50mg533,00€100mg762,00€500mg2.115,00€1g3.142,00€CBS9106
CAS:CBS9106 (SL-801) is a CRM1 inhibitor with CRM1-degrading and anti-tumor activity that inhibits CRM1-dependent nuclear export.Formula:C18H21ClF3N3O3Purezza:98.98%Colore e forma:SolidPeso molecolare:419.83CZL55
CAS:CZL55 is a potent caspase-1 inhibitor with an IC50 value of 0.024 μM.CZL55 has low cytotoxicity and can be used in the study of febrile seizures (FS).Formula:C20H22N2O6Purezza:98.19%Colore e forma:SolidPeso molecolare:386.4TC-DAPK 6
CAS:TC-DAPK 6 is an ATP-competitive inhibitor of Death-associated protein kinase (DAPK) with IC50s of 69 and 225 nM for DAPK1 and DAPK3.Formula:C17H12N2O2Purezza:98.73%Colore e forma:SolidPeso molecolare:276.29PARP/PI3K-IN-1
CAS:PARP/PI3K-IN-1 is a PARP and PI3K dual inhibitor with anticancer and antiproliferative activities for the study of breast, pancreatic and lung cancers.Formula:C33H28F4N8O3Purezza:99.59%Colore e forma:SolidPeso molecolare:660.62P505-15 Acetate
CAS:P505-15 Acetate inhibits spleen tyrosine kinase, reduces immune response and inflammation, and lowers arthritis severity.
Formula:C21H27N9O3Purezza:99.99%Colore e forma:SolidPeso molecolare:453.5BC 11 hydrobromide
CAS:The compound is a selective urokinase inhibitor (IC50 = 8.2 μM). It also inhibits clot lysis with no effect on clot formation.Formula:C8H12BBrN2O2SPurezza:98.07%Colore e forma:SolidPeso molecolare:290.97D609
CAS:D609 (Tricyclodecan-9-yl-Xanthogenate) has antiviral and antiproliferative activities.D609 acts through competitive inhibition of PC, PC-P and SMS.Formula:C11H15KOS2Purezza:97.67% - 99.56%Colore e forma:Off-White PowderPeso molecolare:266.46RIPK3-IN-1
CAS:RIPK3-IN-1 is a RIPK3 inhibitor (IC50: 9.1 nM) that inhibits c-Met kinase, RIPK1, and RIPK2 activity and can be used to study apoptosis.Formula:C29H25FN4O4Purezza:98.27%Colore e forma:SolidPeso molecolare:512.53Apostatin-1
CAS:Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 can bind to a pocket on the N-terminal TRAF2 binding domain of TRADD.Formula:C19H27N3OSPurezza:99.31%Colore e forma:SolidPeso molecolare:345.5Ref: TM-T9079
1mg34,00€2mg49,00€5mg74,00€1mL*10mM (DMSO)82,00€10mg113,00€25mg222,00€50mg358,00€100mg530,00€500mg1.153,00€UCB-5307
CAS:UCB-5307 inhibits TNFR1, binds TNFα with 9 nM KD, shows slow kinetics (KD=6 nM), and penetrates hTNF/hTNFR1 complexes.Formula:C22H21N3OPurezza:98.76%Colore e forma:SolidPeso molecolare:343.42Tiomolibdate diammonium
CAS:Tiomolibdate diammonium (NSC-286644) blocks SOD1 and COX, acting as an antiangiogenic and antitumor agent.Formula:H8MoN2S4Purezza:98%Colore e forma:Brown To Black Iridescent Crystalline PowderPeso molecolare:260.28Gallium maltolate
CAS:Gallium maltolate is a ribonucleoside-diphosphate reductase inhibitor.Formula:C18H15GaO9Purezza:99.61% - 99.67%Colore e forma:SolidPeso molecolare:445.03Vamotinib
CAS:Vamotinib (PF-114) is a tyrosine kinase inhibitor with antiproliferative and antitumor activity.Vamotinib is used in the study of Alzheimer's disease.Formula:C29H27F3N6OPurezza:99.64%Colore e forma:SolidPeso molecolare:532.56Ref: TM-T63746
1mg101,00€5mg245,00€1mL*10mM (DMSO)288,00€10mg401,00€25mg717,00€50mg982,00€100mg1.341,00€200mg1.783,00€MJN68390
CAS:MJN68390 has an apparent IC50 value of 15 μM against CASP8 and shows no activity against CASP10.Formula:C24H28ClN3O3Purezza:98.86%Colore e forma:SolidPeso molecolare:441.95RO-5963
CAS:RO-5963 is a dual inhibitor of p53-MDM2 and p53-MDMX (IC50s: ~17 nM and ~24 nM, respectively).Formula:C24H21ClF2N4O5Purezza:99.28%Colore e forma:SolidPeso molecolare:518.9Ref: TM-T16771
1mg66,00€5mg187,00€1mL*10mM (DMSO)212,00€10mg269,00€25mg411,00€50mg532,00€100mg740,00€200mg982,00€TNIK-IN-3
CAS:TNIK-IN-3 is a highly potent and orally active inhibitor of Traf2- and Nck-interacting protein kinase (TNIK).Formula:C23H18FN3O2Purezza:98.39%Colore e forma:SolidPeso molecolare:387.411G244
CAS:1G244 is an inhibitor of DPP8/9 with antiatherosclerotic and antimyeloma properties.Formula:C29H30F2N4O2Purezza:99.14%Colore e forma:SolidPeso molecolare:504.57F16
CAS:F16 ((E)-4-(3-indolylvinyl)-N-methylpyridinium iodide) inhibits the growth of neu-overexpressing cells and the proliferation of mammary epithelial.Formula:C16H15IN2Purezza:99.89%Colore e forma:SolidPeso molecolare:362.21Droloxifene
CAS:Droloxifene, a tamoxifen derivative and oral SERM, induces p53 and apoptosis; Fluroxifene protects bone, blocks estrogen and implantation.Formula:C26H29NO2Purezza:99.86% - 99.97%Colore e forma:Solid PowderPeso molecolare:387.51Ref: TM-T11098
500mgPrezzo su richiesta1mg51,00€5mg110,00€1mL*10mM (DMSO)126,00€10mg166,00€25mg268,00€50mg396,00€100mg532,00€FA16
FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16Formula:C22H27F3N4O2SPurezza:99.44%Colore e forma:SolidPeso molecolare:468.54Sabizabulin
CAS:Sabizabulin (ABI-231) is a potent, orally bioavailable α- and β-tubulin inhibitor.Cost-effective and quality-assured.Formula:C21H19N3O4Purezza:98.10% - 99.79%Colore e forma:SolidPeso molecolare:377.39Ref: TM-T17228
1mg75,00€2mg99,00€5mg164,00€10mg255,00€25mg487,00€50mg803,00€100mg1.324,00€200mg1.783,00€JY-2
CAS:JY-2 is a forkhead transcription factor O1 (FoxO1) inhibitor with antidiabetic activity that inhibits FoxO1 transcription and can be used to study psoriasis.Formula:C13H7Cl2N3OPurezza:99.66%Colore e forma:SolidPeso molecolare:292.12DK419
CAS:DK419 is an orally active inhibitor of Wnt/β-catenin signaling, with an IC50 of 0.19 μM.Formula:C16H8ClF6N3OPurezza:99.63%Colore e forma:SolidPeso molecolare:407.7CP 461
CAS:CP 461 is a PDE2A inhibitor that promotes apoptosis in cancer cells without affecting normal cells or COX-1/2.Formula:C25H22ClFN2OPurezza:99.82%Colore e forma:SolidPeso molecolare:420.91GS-9191
CAS:GS-9191 is a potent inhibitor of DNA polymerase alpha and ß , a prodrug of the novel nucleoside analogue 9-(2-phosphonomethoxyethyl)guanine (PMEG) , whichFormula:C37H51N8O6PPurezza:98.01 - 99.28%Colore e forma:SolidPeso molecolare:734.82UK-101
CAS:UK-101 is a potent and selective inhibitor of the immunoproteasome LMP2, inhibiting β1i (LMP2), β1c (LMP2), and β5 (LMP2), with IC50s of 104 nM, 15 μM, and 1 μMFormula:C25H48N2O5SiPurezza:98.97% - 99.08%Colore e forma:SolidPeso molecolare:484.74W146
CAS:W146 is an S1PR1 antagonist that induces a significant but transient decrease in blood lymphocytes in mice.Formula:C16H27N2O4PPurezza:99.37%Colore e forma:SolidPeso molecolare:342.37Ref: TM-T13327
1mL*10mM (DMSO)Prezzo su richiesta1mg105,00€5mg409,00€10mg708,00€25mg1.414,00€50mg2.268,00€Ro24-7429
CAS:Ro24-7429: oral HIV-1 Tat antagonist, RUNX1 inhibitor with anti-HIV, antifibrotic, and anti-inflammatory properties.Formula:C14H13ClN4Purezza:99.29% - 99.85%Colore e forma:SolidPeso molecolare:272.73Ref: TM-T28578
1mg87,00€5mg177,00€1mL*10mM (DMSO)203,00€10mg281,00€25mg480,00€50mg692,00€100mg973,00€500mg2.725,00€A 419259 trihydrochloride
CAS:A 419259 trihydrochloride (RK 20449 trihydrochloride) is an Src family kinases inhibitor (IC50s: 9 nM, 3 nM and 3 nM for Src, Lck and Lyn).Formula:C29H37Cl3N6OPurezza:99.75% - 99.96%Colore e forma:SolidPeso molecolare:592DB1976
CAS:DB1976: Selenophene DB270 analog, inhibits PU.1 (IC50=10 nM), disrupts PU.1/DNA (KD=12 nM), induces apoptosis, cell-permeable.Formula:C20H16N8SePurezza:98.74%Colore e forma:SolidPeso molecolare:447.35LQZ-7F
CAS:LQZ-7F is a survivin dimerization inhibitor with anticancer activity.LQZ-7F induces proteasome-dependent survivin degradation and inhibits human tumor growth.Formula:C14H7N9O3Purezza:98.64%Colore e forma:SolidPeso molecolare:349.26HTH-01-091
CAS:HTH-01-091 is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor (IC50: 10.5 nM).HTH-01-091 inhibits PIM1/2/3, RIPK2, DYRK3,Formula:C26H28Cl2N4O2Purezza:98.82%Colore e forma:SolidPeso molecolare:499.43Ref: TM-T24152
1mg281,00€5mg692,00€1mL*10mM (DMSO)775,00€10mg938,00€25mg1.454,00€50mg1.882,00€100mg2.375,00€Ro 90-7501
CAS:Ro 90-7501, an amyloid β42 (Aβ42) protofibril and TPR-dependent PP5 inhibitor, is a novel cervical cancer cell radiosensitizer that inhibits HCMV.Formula:C20H16N6Purezza:97.21% - 99.72%Colore e forma:SolidPeso molecolare:340.38EGFR-IN-11
CAS:EGFR-IN-11 selectively blocks EGFR-tyrosine kinase and promotes apoptosis; targets EGFRL858R/T790M/C797S, IC50=18 nM; halts cell cycle at G0/G1.Formula:C29H35N9O2SPurezza:99.93%Colore e forma:SolidPeso molecolare:573.71Brigimadlin
CAS:Brigimadlin (BI 907828) is an orally active and highly potent antagonist of the E3 ubiquitin-protein ligase MDM2-p53 with antitumor activity.Formula:C31H25Cl2FN4O3Purezza:98.17%Colore e forma:SolidPeso molecolare:591.46Ref: TM-T69923
1mg150,00€5mg258,00€1mL*10mM (DMSO)335,00€10mg353,00€25mg578,00€50mg879,00€100mg1.314,00€T025
CAS:T025 inhibits CLK1-4 (Kds: 0.074-6.5 nM), shows anti-cancer effects (IC50: 30-300 nM), useful for MYC-related disease research.Formula:C21H18N8Purezza:99.20%Colore e forma:SolidPeso molecolare:382.42Ref: TM-T13058
1mg136,00€5mg334,00€1mL*10mM (DMSO)358,00€10mg500,00€25mg807,00€50mg1.099,00€100mg1.485,00€500mg2.962,00€NecroX-7
CAS:NecroX-7 (LC-280126) is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor.Formula:C24H29N3O3SPurezza:98.22%Colore e forma:SolidPeso molecolare:439.57GSK2593074A
CAS:GSK2593074A (GSK'074) is a programmed necrosis inhibitor that displays inhibitory effects on RIP1 and RIP3.Formula:C27H23N5OSPurezza:99.99%Colore e forma:SolidPeso molecolare:465.57Ref: TM-T11484
1mg108,00€5mg260,00€1mL*10mM (DMSO)286,00€10mg409,00€25mg687,00€50mg964,00€100mg1.288,00€UC-112
CAS:UC-112 is a novel potent IAP inhibitor and potently inhibits cell growth in two human melanoma and two human prostate cancer cell lines (IC50=0.7-3.4 uM).Formula:C22H24N2O2Purezza:99.54%Colore e forma:SolidPeso molecolare:348.44Ref: TM-T17195
500mgPrezzo su richiesta1mg34,00€2mg44,00€5mg70,00€1mL*10mM (DMSO)78,00€10mg99,00€25mg202,00€50mg311,00€100mg445,00€Perphenazine dihydrochloride
CAS:Perphenazine dihydrochloride: Oral dopamine, histamine-1 antagonist; targets D2, D3, 5-HT2A, Alpha-1A; may treat psychiatric disorders, cancer.Formula:C21H28Cl3N3OSPurezza:99.67%Colore e forma:SolidPeso molecolare:476.89Etomoxir
CAS:Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a) (IC50=5-20 nM), inhibits fatty acid oxidation. High-Quality, Low-Cost!Formula:C17H23ClO4Purezza:98% - 99.39%Colore e forma:SolidPeso molecolare:326.82SCFSkp2-IN-2
CAS:SCFSkp2-IN-2, a Skp2 inhibitor, exhibits a dissociation constant (K_D) of 28.77 μM.
Formula:C17H20N4O2Purezza:99.86%Colore e forma:SolidPeso molecolare:312.37Ciglitazone
CAS:Ciglitazone: potent PPARγ agonist, EC50 3 μM, oral hypoglycemic; reduces insulin, blood pressure, Th17 cells, VEGF; halts gastric cancer growth.Formula:C18H23NO3SPurezza:98.23% - 99.84%Colore e forma:White Cyrstalline SolidPeso molecolare:333.45AOH1160
CAS:AOH1160 is an inhibitor of proliferating cell nuclear antigen (PCNA).Formula:C25H20N2O3Purezza:98.46% - 99.52%Colore e forma:SolidPeso molecolare:396.44H2L5186303
CAS:H2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment.Formula:C26H20N2O8Purezza:98.19%Colore e forma:SolidPeso molecolare:488.45Ref: TM-T22835
2mg44,00€5mg64,00€1mL*10mM (DMSO)75,00€10mg94,00€25mg180,00€50mg283,00€100mg465,00€200mg642,00€HS38
CAS:HS38: DAPK-specific ATP-competitive inhibitor; Kds: DAPK1 (300 nM), PIM3 (200 nM), ZIPK (280 nM); useful in smooth muscle disorder research.Formula:C14H12ClN5O2SPurezza:98.19%Colore e forma:SolidPeso molecolare:349.8CTA 056
CAS:CTA 056 is an ITK inhibitor that inhibits the growth of MOLT-4 xenograft tumors in mice and can be used to study autoimmune disorders.Formula:C35H34N6OPurezza:97.22% - 97.76%Colore e forma:SolidPeso molecolare:554.68Antifolate C2
CAS:Antifolate C2 (AGF 154) inhibits tumor growth with 0.14 nM IC, useful in cancer/autoimmune research.Formula:C19H21N5O6SPurezza:99.57%Colore e forma:SolidPeso molecolare:447.46Sarmustine
CAS:SarCNU is an alkylating anticancer drug targeting prostate cancer through p53 pathways and selects P140K MGMT-transduced CD34(+) cells.
Formula:C6H11ClN4O3Purezza:98.29% - 99.71%Colore e forma:SolidPeso molecolare:222.63SYM 2081
CAS:SYM 2081: Kainate receptor agonist, IC50 of 35 nM, depolarizes muscle, lowers EPSP amplitude.Formula:C6H11NO4Purezza:99.63%Colore e forma:SolidPeso molecolare:161.16Necrostatin-5
CAS:Necrostatin-5 (Nec-5) inhibits RIP1 kinase, prevents cell necrosis, and protects Fadd-deficient Jurkat cells with an EC50 of 240 nM.Formula:C19H17N3O2S2Purezza:99.40%Colore e forma:SolidPeso molecolare:383.49CDK9-IN-7
CAS:CDK9-IN-7: selective, oral CDK9/cyclin T inhibitor with 11 nM IC50, stronger than CDK4/6.Formula:C29H37N7O2SPurezza:98.08%Colore e forma:SolidPeso molecolare:547.71Ref: TM-T10745
1mg90,00€5mg208,00€1mL*10mM (DMSO)229,00€10mg304,00€25mg457,00€50mg630,00€100mg845,00€200mg1.121,00€p53-MDM2-IN-1
CAS:p53-MDM2-IN-1 (Example 30), an inhibitor targeting the p53-MDM2/X protein interaction, exhibits a K i value of 23.35 µM.Formula:C23H20ClN3O3Purezza:99.98%Colore e forma:SoildPeso molecolare:421.88Lanperisone HCl
CAS:Lanperisone (NK433) is a potent, long-lasting muscle relaxant that inhibits spinal reflexes via noradrenergic system suppression.Formula:C15H19ClF3NOPurezza:98.67% - >99.99%Colore e forma:SolidPeso molecolare:321.77TAI-1
CAS:TAI-1 is a potent and specific Hec1 inhibitor, which disrupts Hec1-Nek2 protein interaction.Formula:C24H21N3O3SPurezza:99.58%Colore e forma:SolidPeso molecolare:431.51EM-12
CAS:EM-12, a Thalidomide analogue, is more active, stable, and boosts rat colon cancer studies.Formula:C13H12N2O3Purezza:99.34%Colore e forma:SolidPeso molecolare:244.25Deferitazole
CAS:Deferitazole (FBS 0701) is a novel and orally active, selective and high affinity iron chelator.Formula:C18H25NO7SPurezza:99.48%Colore e forma:SolidPeso molecolare:399.46STAT3-IN-13
CAS:STAT3-IN-13 is a STAT3 inhibitor with antiproliferative activity that induces apoptosis and can be used to study breast and liver cancer.Formula:C21H20N6O3SPurezza:98.89%Colore e forma:SolidPeso molecolare:436.49Erastin2
CAS:Erastin2 is an iron death inducer that induces cell death by binding to the lipophilic free radical trapping antioxidant ferrostatin-1 or the iron chelator DFO.
Formula:C36H35ClN4O4Purezza:99.63%Colore e forma:SolidPeso molecolare:623.14Minodronic acid
CAS:Minodronic acid (YM-529) is a P2X2/3 antagonist with anticancer properties, inhibiting cell growth and metastasis, and used in osteoporosis research.Formula:C9H12N2O7P2Purezza:99.39%Colore e forma:SolidPeso molecolare:322.15CCT018159
CAS:CCT018159: ATP-competitive HSP90 inhibitor, IC50 3.2 μM (human), 6.6 μM (yeast), blocks invasion, angiogenesis, induces G1 arrest and apoptosis.
Formula:C20H20N2O4Purezza:98.78% - 99.79%Colore e forma:SolidPeso molecolare:352.38Stemazole
CAS:Stemazole activates human stem cell growth, boosts survival, reduces cell death, and aids myelin repair, with therapeutic potential in demyelinating diseases.Formula:C9H9N5OS2Purezza:98.59%Colore e forma:SolidPeso molecolare:267.33Ref: TM-T28866
1mg52,00€1mL*10mM (DMSO)95,00€5mg101,00€10mg164,00€25mg334,00€50mg532,00€100mg858,00€200mg1.149,00€Bomedemstat ditosylate
CAS:Bomedemstat (IMG-7289) is an LSD1 inhibitor for acute myeloid leukemia, MDS, and Myelofibrosis; induces apoptosis by regulating p53, PUMA, and BCLXL.Formula:C42H50FN7O8S2Purezza:99.05%Colore e forma:SolidPeso molecolare:864.02Ref: TM-T70008
1mg84,00€5mg177,00€1mL*10mM (DMSO)250,00€10mg264,00€25mg444,00€50mg640,00€100mg893,00€GSK-2245035 maleate
CAS:GSK-2245035 maleate is a selective Toll-like receptor 7 (TLR7) agonist with preferential Type-1 interferon (IFN)-stimulating properties.Formula:C24H38N6O6Colore e forma:SolidPeso molecolare:506.6CUR61414
CAS:CUR61414 is a cell-permeable inhibitor of Hedgehog signaling pathway (IC50 =100-200 nM) and selectively binds to smoothened (Ki = 44 nM).Formula:C31H42N4O5Purezza:97.34% - 98%Colore e forma:SolidPeso molecolare:550.69Ref: TM-T15019
1mg50,00€2mg71,00€5mg104,00€1mL*10mM (DMSO)116,00€10mg168,00€25mg326,00€50mg492,00€100mg738,00€200mg973,00€S-Adenosyl-L-methionine (1,4-butanedisulfonate)
CAS:S-Adenosyl-L-methionine (SAMe) 1,4-butanedisulfonate functions as an orally active methyl group donor and serves as a dietary supplement known for itsFormula:C19H32N6O11S3Purezza:98%Colore e forma:SolidPeso molecolare:616.69WEHI-345 analog
CAS:WEHI-345 analog is an Src inhibitor.Formula:C23H25N7OPurezza:98%Colore e forma:SolidPeso molecolare:415.49FLT3-IN-14
CAS:FLT3-IN-14: FLT3 inhibitor; FLT3-WT IC50=5.6nM, FLT3-ITD IC50=1.4nM; blocks Y591 phosphorylation; G1 arrest; pro-apoptotic.Formula:C25H24N6O2SColore e forma:SolidPeso molecolare:472.56Thaspine acetate
CAS:Thaspine: inhibits topoisomerase IB, reduces VEGF, stops endothelial cell growth via PI3K/MAPK pathways.Formula:C22H23NO8Colore e forma:SolidPeso molecolare:429.425NLRP3 agonist 1
CAS:Vatalanib hydrochloride (PTK787 hydrochloride) is a VEGF inhibitor that reduces the number and area of Aβ plaques in the cortex of 5xFAD mice.Formula:C15H16N6Purezza:99.01%Colore e forma:SolidPeso molecolare:280.33FGFR-IN-8
CAS:FGFR-IN-8, potent oral FGFR inhibitor for wild-type/mutant types, induces apoptosis with anti-cancer properties.Formula:C27H31Cl2N9O2Colore e forma:SolidPeso molecolare:584.5SD 1008
CAS:SD 1008 is a JAK2/STAT3 signaling pathway inhibitor. SD 1008 inhibits activation of STAT3, JAK2, and Src.Formula:C18H19NO5Purezza:98%Colore e forma:SolidPeso molecolare:329.35RIPK1-IN-10
CAS:RIPK1-IN-10 is a potent inhibitor of RIPK1.Formula:C30H28F2N6O4Colore e forma:SolidPeso molecolare:574.58Mcl-1 inhibitor 17
CAS:Mcl-1 Inhibitor 17 is a compound that functions as an inhibitor of the Mcl-1 protein, specifically designed for use in cancer and other disease research [1].Formula:C27H25FN4O2Colore e forma:SolidPeso molecolare:456.51Ponicidin
CAS:Ponicidin, a diterpenoid from Rabdosia rubescens, has immunoregulatory, anti-inflammatory, anti-viral, and anti-cancer properties.Formula:C20H26O6Purezza:98.98% - 99.92%Colore e forma:SolidPeso molecolare:362.42CNDAC
CAS:CNDAC, a nucleoside analog, is a major metabolite of oral drug sapacitabine.Formula:C10H12N4O4Purezza:98%Colore e forma:SolidPeso molecolare:252.23PRMT6-IN-3
CAS:PRMT6-IN-3 is a selective PRMT6 inhibitor with an IC50 value of 192 nM.PRMT6-IN-3 has anticancer activity and induces apoptosis in cancer cells.Formula:C19H26N4O2SPurezza:98.12%Colore e forma:SolidPeso molecolare:374.5RUNX-IN-1
CAS:RUNX-IN-1, also known as Compound Conjugate 1, covalently attaches to RUNX-binding sequences, thereby preventing RUNX proteins from associating with theirFormula:C71H88Cl2N24O11Purezza:98%Colore e forma:SolidPeso molecolare:1524.52CPUY201112
CAS:CPUY201112, a novel inhibitor of heat shock protein Hsp90, induces p53-mediated apoptosis in MCF-7 cells.Formula:C19H23N3O4Colore e forma:SolidPeso molecolare:357.4HSP90/mTOR-IN-1
"HSP90/mTOR-IN-1 is a dual Hsp90/mTOR inhibitor (IC50: 69/29 nM), halting SW780 cell growth and inducing apoptosis/autophagy in cancer research."Formula:C36H34ClFN6O5SColore e forma:SolidPeso molecolare:717.21ST1074
CAS:ST1074, a dual inhibitor of CerS2 and CerS4, promotes apoptosis and is applicable in cancer research [1].Formula:C20H36ClNO3Purezza:98%Colore e forma:SolidPeso molecolare:373.96IM156
CAS:IM156, a Metformin derivative, activates AMPK, enhances cognition in aging animals, and inhibits OXPHOS in solid tumor research.Formula:C13H16F3N5OPurezza:99.67%Colore e forma:SolidPeso molecolare:315.29RIP2 kinase inhibitor 2
CAS:RIP2 kinase inhibitor 2 is a receptor-interacting protein-2 kinase inhibitor.Formula:C21H28N4O4SPurezza:98%Colore e forma:SolidPeso molecolare:432.54C 87
CAS:C 87: Small-molecule TNF-α inhibitor, binds TNFα, inhibits cytotoxicity with IC50 of 8.73 μM, blocks signaling.Formula:C24H15ClN6O3SPurezza:≥98%Colore e forma:SolidPeso molecolare:502.93BRD4 Inhibitor-18
CAS:BRD4 Inhibitor-18: potent (IC50: 110 nM), impairs MV-4-11 cell growth, disrupts G0/G1 phase, and induces apoptosis.Formula:C26H26ClN3O3SColore e forma:SolidPeso molecolare:496.02CR-1-31-B
CAS:CR-1-31-B, a synthetic rocaglate, inhibits eIF4A, hinders protein synthesis initiation, and induces apoptosis in cancer cells.Formula:C28H29NO8Colore e forma:SolidPeso molecolare:507.539ERα antagonist 1
CAS:ERα antagonist 1 is a selective, potent, covalent estrogen receptor alpha (ERα) antagonist that blocks the cell cycle of MCF-7 cells in G0/G1 phase and inducesFormula:C33H32N2O5SColore e forma:SolidPeso molecolare:568.68LSD1-IN-25
CAS:LSD1-IN-25: potent, selective oral LSD1 inhibitor; IC50=46 nM, Ki=30.3 nM; induces cancer cell apoptosis.Formula:C32H33ClN6O3SPurezza:98%Colore e forma:SolidPeso molecolare:617.16IK-862
CAS:IK-862 is a selective TACE inhibitor with potential anti-inflammatory and anticancer activity for the study of neuritis.Formula:C25H27N3O4Purezza:97.75% - 98.29%Colore e forma:SolidPeso molecolare:433.5eIF4A3-IN-18
CAS:eIF4A3-IN-18, a silvestrol analogue with EC50s: 0.8/35/2 nM, inhibits eIF4F complex and is cytotoxic (LC50: 0.06 nM) for cancer research.Formula:C29H28N2O6Colore e forma:SolidPeso molecolare:500.54HJC0152 free base
CAS:HJC0152 (free base) is an orally active, potent STAT3 inhibitor that impedes cell cycle progression, induces apoptosis, and notably reduces MDA-MB-231 xenograftFormula:C15H13Cl2N3O4Purezza:98%Colore e forma:SolidPeso molecolare:370.19Z-YVAD-CMK
CAS:Z-YVAD-CMK is an inhibitor of both caspase-1 and caspase-3, as referenced in [1].Formula:C30H37ClN4O9Purezza:98%Colore e forma:SolidPeso molecolare:633.09Merodantoin
CAS:Merodantoin induces apoptosis in KRAS-mutant cancer cells via ROS-autophagy and Akt pathway.Formula:C11H18N2O2SPurezza:99.8%Colore e forma:SolidPeso molecolare:242.34Ref: TM-T33296
1mg77,00€1mL*10mM (DMSO)138,00€5mg155,00€10mg220,00€25mg338,00€50mg472,00€100mg632,00€200mg853,00€
