Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(8 prodotti)
- Caspasi(147 prodotti)
- FOXO1(3 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(140 prodotti)
- PDK(9 prodotti)
- PERK(26 prodotti)
- Chinasi di serina/treonina(19 prodotti)
- Survivin(14 prodotti)
- TNF(91 prodotti)
- c-RET(61 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 6114 prodotti di "Apoptosi"
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4-Epianhydrotetracycline hydrochloride
CAS:EATC, a tetracycline byproduct, combats Pseudomonas to E. coli with MIC50s of 0.75-16 mg/L.Formula:C22H23ClN2O7Colore e forma:SolidPeso molecolare:462.88XY077
XY077 (compound 14a) is a RORγ inverse agonist with an IC50 value of 0.004 μM. It induces cell apoptosis (cellapoptosis) and exhibits antiproliferative activity both in vitro and in vivo.Formula:C27H27F3N2O5S2Peso molecolare:580.13135(±)-Silybin
CAS:(±)-Silybin, a racemate of Silybin, demonstrates a range of biological activities including inducing apoptosis and possessing hepatoprotective, antioxidant, anti-inflammatory, and anti-cancer properties [1] [2].Formula:C25H22O10Colore e forma:SolidPeso molecolare:482.44Sec61-IN-4
Sec61-IN-4 (Compound 16b) is a potent Sec61 inhibitor with an IC50 value of 0.04 nM in U87-MG cells [1].Colore e forma:Odour Solidβ-Glucuronide-dPBD-PEG5-NH2 TFA
CAS:β-Glucuronide-dPBD-PEG5-NH2 TFA is a β-glucuronide-linked pyrrolobenzodiazepine dimer employed in the synthesis of the antibody-drug conjugate (ADC) cIRCR201-Formula:C80H102F3N7O37Colore e forma:SolidPeso molecolare:1810.69Thiocolchicine
CAS:Thiocolchicine inhibits tubulin polymerization (IC50: 2.5 µM, Ki: 0.7 µM), induces apoptosis, and serves as an ADC cytotoxin.Formula:C22H25NO5SPurezza:98.19%Colore e forma:SolidPeso molecolare:415.5Z-Asp-CH2-DCB
CAS:Z-Asp-CH2-DCB is an irreversible inhibitor of broad spectrum caspase.Formula:C20H17Cl2NO7Purezza:99.08%Colore e forma:SolidPeso molecolare:454.26STAT3-D11-PROTAC-VHL
STAT3-D11-PROTAC-VHL (Compound D11-PROTAC) is a PROTAC degrader targeting signal transducer and activator of transcription 3 (STAT3). It demonstrates anti-tumor activity with IC50 values of 1335 nM in HeLa cells and 1973 nM in MCF-7 cells. The compound binds to the DNA binding domain of STAT3, recruits the E3 ligase VHL to form a ternary complex, leading to ubiquitination and subsequent proteasomal degradation of STAT3. Additionally, STAT3-D11-PROTAC-VHL inhibits tumor cell growth, induces cell cycle arrest and apoptosis (apoptosis), and suppresses tumor immune evasion.Colore e forma:Odour SolidTebentafusp
CAS:Tebentafusp (IMCgp100) is a protein that targets gp100 with potential anti-tumor activity.Purezza:97.2% (SDS-PAGE); 100% (SEC-HPLC) - 97.2% (SDS-PAGE); 100% (SEC-HPLC)Colore e forma:LiquidARV-393 HCl
ARV-393 HCl is an orally active and potent PROTAC targeting BCL6 with antitumor activity for the study of non-Hodgkin's lymphoma.Formula:C46H54Cl2FN9O7Purezza:99.79%Colore e forma:SolidPeso molecolare:934.882,2'-Dihydroxy chalcone
CAS:2,2'-Dihydroxy chalcone inhibits β-glucuronidase (IC50=1.6 μM) and lysozyme (IC50=1.4 μM), and fights E. coli, S. fowleri, S. albicans, S. aureus.Formula:C15H12O3Purezza:99.70%Colore e forma:SolidPeso molecolare:240.25PROTAC GPX4 degrader-1
CAS:PROTAC GPX4 Degrader-1 (DC-2) is a PROTAC-based compound that efficiently degrades GPX4, demonstrating a degradation concentration (DC 50) of 0.03 μM in HT1080Formula:C50H57ClN10O10Colore e forma:SolidPeso molecolare:993.5Thalidomide-O-C6-NH2
CAS:Thalidomide-O-C6-NH2 is a synthesized E3 ligase ligand-linker conjugate used in the PROTAC dTAG-13, a degrader of FKBP12F36V and BET[1].Formula:C19H23N3O5Purezza:98%Colore e forma:SolidPeso molecolare:373.4HDAC6-IN-22
HDAC6-IN-22 (compound 30), an HDAC6 inhibitor, exhibits an IC50 of 4.63 nM and demonstrates antiproliferative effects against multiple myeloma both in vitro andFormula:C24H24N4O2Purezza:98%Colore e forma:SolidPeso molecolare:400.47PROTAC Bcl-xL degrader-2
PROTAC Bcl-xL degrader-2, based on von Hippel-Lindau ligand, is a potent degrader of Bcl-xL (a Bcl-2 family member), demonstrating an IC 50 of 0.6 nM.Formula:C68H80N8O14S3Colore e forma:SolidPeso molecolare:1329.6Enlonstobart
CAS:Enlonstobart is a humanized IgG4-κ monoclonal antibody targeting PDCD1, functioning as both an immunostimulant and antineoplastic agent [1].Colore e forma:LiquidRMC-6291
CAS:RMC-6291: Oral, covalent KRAS G12C inhibitor, blocks signaling, forms tri-complex with CypA, suppresses RAS activity in tumors.Formula:C55H78FN9O8Purezza:98.73% - 99.92%Colore e forma:SolidPeso molecolare:1012.26Disitertide
CAS:Disitertide (P144) is an inhibitor of TGF-β1.Formula:C68H109N17O22S2Purezza:98%Colore e forma:SolidPeso molecolare:1580.84Tectorigenin sodium sulfonate
CAS:Tectorigenin sodium sulfonate, a derivative of tectorigenin, is synthesized through sulfonation with sulfuric acid followed by neutralization in saturatedFormula:C16H11NaO9SColore e forma:SolidPeso molecolare:402.31Pimagedine
CAS:Pimagedine is a prototype therapeutic agent for the prevention of formation of advanced glycation endproducts.Formula:CH6N4Colore e forma:SolidPeso molecolare:74.09
