Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(11 prodotti)
- Caspasi(142 prodotti)
- FOXO1(3 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(138 prodotti)
- PDK(9 prodotti)
- PERK(25 prodotti)
- Chinasi di serina/treonina(14 prodotti)
- Survivin(14 prodotti)
- TNF(89 prodotti)
- c-RET(56 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 5903 prodotti di "Apoptosi"
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A-1248767
CAS:<p>A-1248767, a derivative of A-1210477, is an MCL-1 inhibitor (IC50=23.9 nM; Ki=0.41 nM) known for its anticancer properties. It binds to MCL-1 with high affinity, induces an increase in MCL-1 protein levels inside cells, and promotes apoptosis in tumor cells.</p>Formula:C47H55N7O6Colore e forma:SolidPeso molecolare:813.98Anagrelide hydrochloride monohydrate
CAS:Anagrelide HCl monohydrate is a platelet-reducing imidazoquinazoline for ET and PV research.Formula:C10H10Cl3N3O2Colore e forma:SolidPeso molecolare:310.56Ferroptosis-IN-13
<p>Ferroptosis-IN-13 (compound NY-26) is an inhibitor of ferroptosis. It effectively suppresses RSL3-induced ferroptosis in 786-O cells, with an EC50 value of 62 nM.</p>Formula:C32H30F2N4O3Colore e forma:SolidPeso molecolare:556.602Ganglioside GD3 disodium salt
CAS:<p>Ganglioside GD3 disodium salt is a melanoma-associated antigen often targeted in immune therapy for melanomas.</p>Formula:C70H123N3Na2O29Colore e forma:SolidPeso molecolare:1516.71Z-Ala-Ala-Asp-CMK
CAS:<p>Z-Ala-Ala-Asp-CMK (Z-AAD-CMK) is a selective granzyme B inhibitor that blocks granzyme B protease activity, for inflammatory diseases and tumours.</p>Formula:C19H24ClN3O7Purezza:99.967%Colore e forma:SolidPeso molecolare:441.86RA-XII
CAS:RA-XII is a useful organic compound for research related to life sciences. The catalog number is T125868 and the CAS number is 143343-98-0.Formula:C46H58N6O14Colore e forma:SolidPeso molecolare:918.998MBC-11 trisodium
CAS:MBC-11 trisodium, a bisphosphonate-Ara-C conjugate, may treat TIBD.Formula:C11H17N3Na3O14P3Purezza:98%Colore e forma:SolidPeso molecolare:577.16Thalidomide-Piperazine-PEG2-NH2
CAS:Thalidomide-Piperazine-PEG2-NH2 is a synthetic E3 ligase ligand-linker for PROTAC, combining cereblon ligand with a PEG2 linker.Formula:C23H31N5O6Colore e forma:SolidPeso molecolare:473.53Enniatin complex
CAS:<p>Enniatin complex: fungal cyclohexadepsipeptides inhibit enzymes, induce cancer cell apoptosis, and have ionophoric, antibiotic, and hypolipidemic effects.</p>Purezza:98%Colore e forma:SolidNofazinlimab
CAS:<p>Nofazinlimab (CS1003) is a human anti-PD-1 IgG4 monoclonal antibody for the study of unresectable hepatocellular carcinoma (uHCC).</p>Purezza:98.6% (SDS-PAGE); 99.7% (SEC-HPLC) - 98.6% (SDS-PAGE); 99.7% (SEC-HPLC)Colore e forma:Liquidp53 and MDM2 proteins-interaction-inhibitor (racemic)
CAS:p53 and MDM2 proteins-interaction-inhibitor (racemic) is an inhibitor of the interaction between p53 and MDM2 proteins.Formula:C40H49Cl2N5O4Purezza:98%Colore e forma:SolidPeso molecolare:734.75MEK/PI3K-IN-2
CAS:<p>MEK/PI3K-IN-2 is a potent dual inhibitor (MEK1 IC50: 352 nM, PI3Kα: 107 nM, PI3Kδ: 137 nM) that reduces pAKT, pERK1/2, and hinders tumor cell growth.</p>Formula:C38H41F5IN9O7Colore e forma:SolidPeso molecolare:957.68Thalidomide-NH-PEG2-COOH
CAS:<p>Thalidomide-NH-PEG2-COOH: a synthesized E3 ligase ligand-linker with cereblon ligand and PROTAC linker.</p>Formula:C20H23N3O8Colore e forma:SolidPeso molecolare:433.417DA5-HTL
DA5-HTL is a compound that combines dasatinib with the HaloTag system, effectively inhibiting the growth of tumor cells, with a GI50 of 1.923 nM.Formula:C39H58Cl2N8O8SPeso molecolare:868.34754Waltonitone
CAS:<p>Waltonitone is a natural ursane-type pentacyclic triterpene isolated from Gentian waltonii Burkill.</p>Formula:C30H48O2Purezza:98%Colore e forma:SolidPeso molecolare:440.7PD-L1-IN-5
<p>PD-L1-IN-5 (X22) is an orally active PD-L1 inhibitor with an IC50 of 785.6 nM, demonstrating antitumor activity in vivo.</p>GPLGIAGQ
CAS:GPLGIAGQ, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting.Formula:C31H53N9O10Purezza:98%Colore e forma:SolidPeso molecolare:711.81ERK-IN-6
ERK-IN-6, a potent agent, inhibits ESCC growth and induces apoptosis through the ERK pathway.Formula:C19H18BrN3O3SColore e forma:SolidPeso molecolare:448.33P1D-34
<p>P1D-34 is a Pin1 PROTAC degrader with a DC50 value of 177 nM. It downregulates Pin1 substrate proteins, including Cyclin D1, Rb, Mcl-1, Akt, and c-Myc. Additionally, P1D-34 exhibits antiproliferative activity across various acute myeloid leukemia (AML) cell lines and induces DNA damage and apoptosis by generating reactive oxygen species (ROS).</p>Colore e forma:Odour SolidEGFR-IN-107
<p>EGFR-IN-107 (compound 3r) is an orally active EGFR inhibitor with IC50 values of 0.4333 μM for EGFRWT and 0.0438 μM for EGFRL858R/T790M. It exhibits antiproliferative activity, effectively inhibiting the proliferation of H1975 cells and inducing apoptosis (apoptosis). EGFR-IN-107 is applicable in cancer research.</p>Formula:C34H36FN7O2Peso molecolare:593.29145
