Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(11 prodotti)
- Caspasi(142 prodotti)
- FOXO1(3 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(138 prodotti)
- PDK(9 prodotti)
- PERK(25 prodotti)
- Chinasi di serina/treonina(14 prodotti)
- Survivin(14 prodotti)
- TNF(89 prodotti)
- c-RET(56 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 5903 prodotti di "Apoptosi"
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TH1834 dihydrochloride
CAS:TH1834 dihydrochloride is a specific Tip60 histone acetyltransferase inhibitor.Formula:C33H42Cl2N6O3Purezza:98%Colore e forma:SolidPeso molecolare:641.63SCAL-266
CAS:SCAL-266, a potent inhibitor of mitochondrial complex I (CI), exhibits an IC50 of 0.83 μM.Formula:C27H28F3N5O2Purezza:98%Colore e forma:SolidPeso molecolare:511.54pan-HER-IN-1
CAS:<p>Compound C5: Irreversible, oral pan-HER inhibitor with low IC50s for EGFR/HERs; induces apoptosis and has antitumor effects.</p>Formula:C19H14BrN5OColore e forma:SolidPeso molecolare:408.25PARP-1-IN-2
CAS:<p>PARP-1-IN-2 is a potent PARP1 inhibitor that crosses the blood-brain barrier (IC50: 149 nM).PARP-1-IN-2 showed significant antiproliferative activity against</p>Formula:C22H15Cl2N3O2Purezza:98.82%Colore e forma:SolidPeso molecolare:424.28Jolkinolide B
CAS:<p>Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud.</p>Formula:C20H26O4Purezza:99.39% - 99.7%Colore e forma:SolidPeso molecolare:330.42Verrucarin J
CAS:Verrucarin J, a Myrothecium fungus metabolite, triggers apoptosis in some cancer cells and fights Candida, Mucor, and JUNV (IC50: 1.2 ng/mL).Formula:C27H32O8Colore e forma:SolidPeso molecolare:484.54Mcl1-IN-11
CAS:Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively.Formula:C38H41N3O5S2Purezza:98%Colore e forma:SolidPeso molecolare:683.88CDK9-IN-18
CAS:CDK9-IN-18: Potent CDK9 blocker, anticancer, induces apoptosis, low cellular activity.Formula:C27H20N8OColore e forma:SolidPeso molecolare:472.5RIPK1-IN-15
CAS:RIPK1-IN-15 (Compound 2.5) is a potent RIPK1 inhibitor that has the potential in neurodegenerative, autoimmune, and inflammatory diseases research [1].Formula:C19H19N3O2Colore e forma:SolidPeso molecolare:321.37SLMP53-2
CAS:SLMP53-2 is a mutant p53 reactivator that restores the wild-type-like conformation and DNA-binding ability of mutp53-Y220C through enhanced interaction withFormula:C26H22N2O2Colore e forma:SolidPeso molecolare:394.47Epirubicin
CAS:Epirubicin, a doxorubicin derivative, is an antineoplastic, inhibits topoisomerase, DNA/RNA synthesis, and Foxp3, reducing T cell activity.Formula:C27H29NO11Colore e forma:SolidPeso molecolare:543.52Gemcitabine monophosphate
CAS:R306465, a potent HDAC1/8 inhibitor, has broad antitumor effects (IC50: 30-300 nM) on solid and blood cancers.Formula:C9H12F2N3O7PColore e forma:SolidPeso molecolare:343.18VRT-043198
CAS:<p>VRT-043198, a VX-765 metabolite, is a potent ICE/caspase-1 inhibitor, crossing the blood-brain barrier with K i of 0.8/0.6 nM.</p>Formula:C22H29ClN4O6Colore e forma:SolidPeso molecolare:480.94Xanthine oxidase-IN-6
Xanthine oxidase-IN-6: potent oral mixed-type XOD inhibitor, IC50 1.37 µM, anti-hyperuricemia, renal protection.Formula:C29H34N2O15Colore e forma:SolidPeso molecolare:650.58MMP-9-IN-5
CAS:MMP-9-IN-5: MMP-9 and AKT inhibitor (IC50: 4.49 nM and 1.34 nM), induces apoptosis for cancer research.Formula:C27H20IN3O4Colore e forma:SolidPeso molecolare:577.37PK9327
CAS:PK9327 is a small-molecule stabilizer that targets cavity-creating p53 cancer mutations.Formula:C21H22N2SColore e forma:SolidPeso molecolare:334.48iMAC2
CAS:iMAC2, a potent MAC (Membrane Attack Complex) inhibitor, exhibits an IC50 of 28 nM and an LD50 of 15,000 nM, demonstrating significant efficacy in inhibitingFormula:C19H20Br2FN3Colore e forma:SolidPeso molecolare:469.19CDK1/Cyc B-IN-1
CAS:CDK1/Cyc B-IN-1: Potent CDK1/Cyc B inhibitor, IC50 97 nM, induces apoptosis, arrests G2/M cycle, halts cancer growth.Formula:C14H12ClN3O2S2Colore e forma:SolidPeso molecolare:353.85MYRA-A
CAS:MYRA-A is an inducer of apoptosis in a Myc-dependent manner that acts by inhibiting Myc-driven transformation and disrupting MYC-Max interaction.Formula:C19H20N2O4Purezza:98%Colore e forma:SolidPeso molecolare:340.37CDK8/19-IN-1
CAS:CDK8/19-IN-1 is a selective and oral bioavailable CDK8/19 dual inhibitor (IC50s: 0.46 nM, 0.99 nM, and 270 nM for CDK8, CDK19, and CDK9).Formula:C19H18N4O4S2Purezza:98%Colore e forma:SolidPeso molecolare:430.5
