
Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(6 prodotti)
- BCL(11 prodotti)
- Caspasi(127 prodotti)
- FOXO1(3 prodotti)
- IAP(65 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(126 prodotti)
- PDK(9 prodotti)
- PERK(24 prodotti)
- Chinasi di serina/treonina(15 prodotti)
- Survivin(13 prodotti)
- TNF(91 prodotti)
- c-RET(51 prodotti)
- p53(62 prodotti)
Mostrare 6 più sottocategorie
Trovati 5622 prodotti di "Apoptosi"
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PDPOB
CAS:<p>PDPOB, a phenyl carboxylic acid derivative, may protect neurons from ischemic damage by reducing mitochondrial issues, oxidative stress, and cell death.</p>Formula:C15H20O5Colore e forma:SolidPeso molecolare:280.32Mutant p53 modulator-1
CAS:<p>Mutant p53 modulator-1 inhibits cancer with p53 mutations; see patent WO2021231474A1, compound 231B.</p>Formula:C27H32F4N8O2Colore e forma:SolidPeso molecolare:576.59PhiKan 083 hydrochloride
CAS:<p>PhiKan 083 HCl: carbazole, binds Y220C (Kd 167 μM), affinity in Ln229 (Kd 150 μM).</p>Formula:C16H19ClN2Purezza:98%Colore e forma:SolidPeso molecolare:274.79CAY10506
CAS:<p>CAY10506, a hybrid lipoic acid-TZD, activates PPARγ to control glucose and lipid levels with an EC50 of 10 μM.</p>Formula:C20H26N2O4S3Colore e forma:SolidPeso molecolare:454.63AMG-548
CAS:AMG-548, oral p38α inhibitor (Ki=0.5 nM), >1000x selectivity over p38γ/δ, blocks TNFα (IC50=3 nM), also inhibits Wnt/Casein kinase 1δ/ε.Formula:C29H27N5OPurezza:99.91%Colore e forma:SolidPeso molecolare:461.56SMIP004
CAS:<p>SMIP004 is an SKP2 E3 ligase inhibitor. SMIP004 is a cancer cell-selective apoptosis inducer of human prostate cancer cells.</p>Formula:C13H19NOPurezza:99.86%Colore e forma:SolidPeso molecolare:205.3SCH529074
CAS:<p>SCH529074 is a selective activator of p53 (Ki = 1 μM) and can be used in studies about non-small-cell lung carcinoma.</p>Formula:C31H36Cl2N6Purezza:99.57%Colore e forma:SolidPeso molecolare:563.56GLS1 Inhibitor-4
CAS:<p>GLS1 Inhibitor-4 (41e) has 11.86 nM IC50, strong binding, disrupts glutamine metabolism, induces apoptosis, and shows antitumor effects.</p>Formula:C29H27F3N10O2S2Purezza:98%Colore e forma:SolidPeso molecolare:668.72PD-1/PD-L1-IN-25
CAS:<p>"PD-1/PD-L1-IN-25 blocks PD-1/PD-L1 (IC50: 16.17 nM), boosting T-cell anti-tumor immunity, useful for cancer research."</p>Formula:C26H24ClN3O5Colore e forma:SolidPeso molecolare:493.94GW837016X
CAS:<p>GW837016X, also known as NEU-391, is a potent inhibitor of protozoan parasite proliferation.</p>Formula:C25H20ClFN4OSColore e forma:SolidPeso molecolare:478.97LOM612
CAS:LOM612 is a potent and specific FOXO relocator FOXO3a reporter protein endogenous FOXO3a and FOXO1 , down-regulates c-Myc and cyclin D1, anti-proliferative.Formula:C13H10N2O2SColore e forma:SolidPeso molecolare:258.3Anti-inflammatory agent 47
CAS:<p>Flo8, an anti-inflammatory and antioxidant agent, effectively suppresses the release of reactive oxygen species (ROS) and nitric oxide (NO) while inhibiting</p>Formula:C25H18N2O3Purezza:98%Colore e forma:SolidPeso molecolare:394.42PHA-680626
CAS:<p>PHA-680626 is a PLK inhibitor, effective on resistant leukemia cells, with IC50: Plk1 (0.53 μM), Plk2 (0.07 μM), Plk3 (1.61 μM).</p>Formula:C23H26N6O2SColore e forma:SolidPeso molecolare:450.56LG308
CAS:<p>LG308, a synthetic compound, has anti-tumor properties, inducing apoptosis and mitotic arrest, thereby suppressing prostate cancer growth.</p>Formula:C19H17FN2OColore e forma:SolidPeso molecolare:308.35Gemcitabine monophosphate
CAS:<p>R306465, a potent HDAC1/8 inhibitor, has broad antitumor effects (IC50: 30-300 nM) on solid and blood cancers.</p>Formula:C9H12F2N3O7PColore e forma:SolidPeso molecolare:343.18NF-κB-IN-5
CAS:<p>NF-κB-IN-5 (compound 4d) is an orally active NF-κB inhibitor.</p>Formula:C23H27N3O4Colore e forma:SolidPeso molecolare:409.48Tubulin polymerization-IN-22
CAS:<p>Tubulin polymerization-IN-22 inhibits tubulin (IC50=8.1μM), blocks G2/M phase, and triggers apoptosis.</p>Formula:C19H16O4Colore e forma:SolidPeso molecolare:308.33AZD-5991 Racemate
CAS:<p>AZD-5991 Racemate is the racemate of AZD-5991. (Rac)-AZD-5991 is a novel Mcl-1 inhibitor induces upregulation of BCL2,BCL-XL, CMYC and MCL1 in AML cell lines.</p>Formula:C35H34ClN5O3S2Colore e forma:SolidPeso molecolare:672.26Atopaxar
CAS:<p>Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.</p>Formula:C29H38FN3O5Purezza:97.07% - 98.07%Colore e forma:SolidPeso molecolare:527.63Mcl1-IN-11
CAS:Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively.Formula:C38H41N3O5S2Purezza:98%Colore e forma:SolidPeso molecolare:683.88
