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Apoptosi

Apoptosi

Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.

Sottocategorie di "Apoptosi"

Mostrare 6 più sottocategorie

Trovati 5622 prodotti di "Apoptosi"

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  • PDPOB

    CAS:
    <p>PDPOB, a phenyl carboxylic acid derivative, may protect neurons from ischemic damage by reducing mitochondrial issues, oxidative stress, and cell death.</p>
    Formula:C15H20O5
    Colore e forma:Solid
    Peso molecolare:280.32
  • Mutant p53 modulator-1

    CAS:
    <p>Mutant p53 modulator-1 inhibits cancer with p53 mutations; see patent WO2021231474A1, compound 231B.</p>
    Formula:C27H32F4N8O2
    Colore e forma:Solid
    Peso molecolare:576.59
  • PhiKan 083 hydrochloride

    CAS:
    <p>PhiKan 083 HCl: carbazole, binds Y220C (Kd 167 μM), affinity in Ln229 (Kd 150 μM).</p>
    Formula:C16H19ClN2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:274.79
  • CAY10506

    CAS:
    <p>CAY10506, a hybrid lipoic acid-TZD, activates PPARγ to control glucose and lipid levels with an EC50 of 10 μM.</p>
    Formula:C20H26N2O4S3
    Colore e forma:Solid
    Peso molecolare:454.63
  • AMG-548

    CAS:
    AMG-548, oral p38α inhibitor (Ki=0.5 nM), >1000x selectivity over p38γ/δ, blocks TNFα (IC50=3 nM), also inhibits Wnt/Casein kinase 1δ/ε.
    Formula:C29H27N5O
    Purezza:99.91%
    Colore e forma:Solid
    Peso molecolare:461.56
  • SMIP004

    CAS:
    <p>SMIP004 is an SKP2 E3 ligase inhibitor. SMIP004 is a cancer cell-selective apoptosis inducer of human prostate cancer cells.</p>
    Formula:C13H19NO
    Purezza:99.86%
    Colore e forma:Solid
    Peso molecolare:205.3
  • SCH529074

    CAS:
    <p>SCH529074 is a selective activator of p53 (Ki = 1 μM) and can be used in studies about non-small-cell lung carcinoma.</p>
    Formula:C31H36Cl2N6
    Purezza:99.57%
    Colore e forma:Solid
    Peso molecolare:563.56
  • GLS1 Inhibitor-4

    CAS:
    <p>GLS1 Inhibitor-4 (41e) has 11.86 nM IC50, strong binding, disrupts glutamine metabolism, induces apoptosis, and shows antitumor effects.</p>
    Formula:C29H27F3N10O2S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:668.72
  • PD-1/PD-L1-IN-25

    CAS:
    <p>"PD-1/PD-L1-IN-25 blocks PD-1/PD-L1 (IC50: 16.17 nM), boosting T-cell anti-tumor immunity, useful for cancer research."</p>
    Formula:C26H24ClN3O5
    Colore e forma:Solid
    Peso molecolare:493.94
  • GW837016X

    CAS:
    <p>GW837016X, also known as NEU-391, is a potent inhibitor of protozoan parasite proliferation.</p>
    Formula:C25H20ClFN4OS
    Colore e forma:Solid
    Peso molecolare:478.97
  • LOM612

    CAS:
    LOM612 is a potent and specific FOXO relocator FOXO3a reporter protein endogenous FOXO3a and FOXO1 , down-regulates c-Myc and cyclin D1, anti-proliferative.
    Formula:C13H10N2O2S
    Colore e forma:Solid
    Peso molecolare:258.3
  • Anti-inflammatory agent 47

    CAS:
    <p>Flo8, an anti-inflammatory and antioxidant agent, effectively suppresses the release of reactive oxygen species (ROS) and nitric oxide (NO) while inhibiting</p>
    Formula:C25H18N2O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:394.42
  • PHA-680626

    CAS:
    <p>PHA-680626 is a PLK inhibitor, effective on resistant leukemia cells, with IC50: Plk1 (0.53 μM), Plk2 (0.07 μM), Plk3 (1.61 μM).</p>
    Formula:C23H26N6O2S
    Colore e forma:Solid
    Peso molecolare:450.56
  • LG308

    CAS:
    <p>LG308, a synthetic compound, has anti-tumor properties, inducing apoptosis and mitotic arrest, thereby suppressing prostate cancer growth.</p>
    Formula:C19H17FN2O
    Colore e forma:Solid
    Peso molecolare:308.35
  • Gemcitabine monophosphate

    CAS:
    <p>R306465, a potent HDAC1/8 inhibitor, has broad antitumor effects (IC50: 30-300 nM) on solid and blood cancers.</p>
    Formula:C9H12F2N3O7P
    Colore e forma:Solid
    Peso molecolare:343.18
  • NF-κB-IN-5

    CAS:
    <p>NF-κB-IN-5 (compound 4d) is an orally active NF-κB inhibitor.</p>
    Formula:C23H27N3O4
    Colore e forma:Solid
    Peso molecolare:409.48
  • Tubulin polymerization-IN-22

    CAS:
    <p>Tubulin polymerization-IN-22 inhibits tubulin (IC50=8.1μM), blocks G2/M phase, and triggers apoptosis.</p>
    Formula:C19H16O4
    Colore e forma:Solid
    Peso molecolare:308.33
  • AZD-5991 Racemate

    CAS:
    <p>AZD-5991 Racemate is the racemate of AZD-5991. (Rac)-AZD-5991 is a novel Mcl-1 inhibitor induces upregulation of BCL2,BCL-XL, CMYC and MCL1 in AML cell lines.</p>
    Formula:C35H34ClN5O3S2
    Colore e forma:Solid
    Peso molecolare:672.26
  • Atopaxar

    CAS:
    <p>Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.</p>
    Formula:C29H38FN3O5
    Purezza:97.07% - 98.07%
    Colore e forma:Solid
    Peso molecolare:527.63
  • Mcl1-IN-11

    CAS:
    Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively.
    Formula:C38H41N3O5S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:683.88