
Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(6 prodotti)
- BCL(11 prodotti)
- Caspasi(127 prodotti)
- FOXO1(3 prodotti)
- IAP(65 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(126 prodotti)
- PDK(9 prodotti)
- PERK(24 prodotti)
- Chinasi di serina/treonina(15 prodotti)
- Survivin(13 prodotti)
- TNF(91 prodotti)
- c-RET(51 prodotti)
- p53(62 prodotti)
Mostrare 6 più sottocategorie
Trovati 5622 prodotti di "Apoptosi"
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Quinidine polygalacturonate
CAS:Quinidine polygalacturonate: oral cytochrome P450db inhibitor, K+ channel blocker (IC50 19.9 μM), induces apoptosis, anti-arrhythmic, aids malaria research.Formula:C26H34N2O9Colore e forma:SolidPeso molecolare:518.22643ZT55
CAS:<p>ZT55: Oral JAK2 inhibitor, IC50: 0.031 μM, hinders JAK2 V617F HEL cell growth, induces apoptosis, arrests cell cycle, effective in mice HEL tumor studies.</p>Formula:C17H16N2O3Colore e forma:SolidPeso molecolare:296.32DMH2
CAS:<p>DMH2 is an antagonist of bone morphogenetic protein (BMP) type I receptor. It acts by decreasing growth and inducing cell death of lung cancer cell lines.</p>Formula:C27H25N5O2Purezza:98%Colore e forma:SolidPeso molecolare:451.52CDK/HDAC-IN-2
CAS:<p>CDK/HDAC-IN-2 inhibits HDAC1,2,3, CDK1,2, induces G2/M arrest, apoptosis, and shows anti-tumor effects.</p>Formula:C25H20Cl2N6O3Colore e forma:SolidPeso molecolare:523.37Anticancer agent 42
CAS:<p>Oral anticancer 42 targets MDA-MB-231 cells; IC50 0.07μM; triggers apoptosis, enhances p53. Useful for metastatic breast cancer study.</p>Formula:C19H16Cl2N2O3Colore e forma:SolidPeso molecolare:391.25Anticancer agent 56
CAS:<p>Anticancer agent 56 (4d) has potent action <3μM IC50 on various cancers, causing G2/M arrest and mitochondrial apoptosis via ROS and caspase activation.</p>Formula:C20H18ClN3O3Colore e forma:SolidPeso molecolare:383.83(S)-Erypoegin K
CAS:<p>(S)-Erypoegin K is a potent anticancer agent that demonstrates strong anti-proliferative activity against HL-60 cells and induces apoptosis.</p>Formula:C20H18O6Colore e forma:SolidPeso molecolare:354.35(Rac)-Indoximod
CAS:<p>(Rac)-Indoximod, a robust IDO inhibitor, and IFN-γ combo reduce α-SMA hCM activity and boost apoptosis, aiding cardiac fibrosis.</p>Formula:C12H14N2O2Colore e forma:SolidPeso molecolare:218.25AG311
CAS:<p>AG311 inhibits complex I; destabilizes HIF-1α; triggers necrosis in cancer cells, mitochondrial depolarization, superoxide, and calcium increase.</p>Formula:C17H15N5SColore e forma:SolidPeso molecolare:321.4Antiproliferative agent-11
<p>Antiproliferative agent-11, a Ruthenium(II) complex, targets multiple cancers with IC50s of 6-10 μM.</p>Formula:C31H34Cl2N6O3P2RuColore e forma:SolidPeso molecolare:772.56CGP 65015
CAS:<p>CGP 65015 is an oral iron chelator and can mobilize iron deposits.</p>Formula:C14H15NO4Purezza:98%Colore e forma:SolidPeso molecolare:261.27PHM16
CAS:<p>PHM16 is an ATP competitive FAK and FGFR2 inhibitor.</p>Formula:C20H22N6O4Purezza:98%Colore e forma:SolidPeso molecolare:410.43ARN 14494
CAS:<p>ARN 14494, a potent SPT inhibitor (IC50=27.3 nM), reduces ceramide synthesis and neuroinflammation, and protects against β-amyloid toxicity.</p>Formula:C24H32N4O3Colore e forma:SolidPeso molecolare:424.54PARP1/BRD4-IN-1
CAS:<p>PARP1/BRD4-IN-1 selectively inhibits PARP1 (49 nM IC50) and BRD4 (202 nM IC50), hindering pancreatic cancer cell growth.</p>Formula:C29H26N6O3Colore e forma:SolidPeso molecolare:506.56Apogossypolone (ApoG2)
CAS:<p>Apogossypolone (ApoG2) is a semi-synthesized derivative of gossypol which is a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins with K i</p>Formula:C28H26O8Colore e forma:SolidPeso molecolare:490.5RIPK1-IN-11
CAS:<p>RIPK1-IN-11, an oral RIPK1 blocker, Kd 9.2 nM, IC50 67 nM, prevents necrosis and inflammation in cells.</p>Formula:C23H24N4O4SColore e forma:SolidPeso molecolare:452.53ISC-4
CAS:<p>ISC-4 is an Akt inhibitor, which activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model.</p>Formula:C11H13NSeColore e forma:SolidPeso molecolare:238.19DRAK1/2-IN-1
CAS:<p>DRAK1/2-IN-1 is a potent inhibitor targeting both DRAK1 and DRAK2, displaying dissociation constants (Kd) of 1 µM and 6 µM, respectively.</p>Formula:C22H24N2O3SColore e forma:SolidPeso molecolare:396.5PD-1/PD-L1-IN 5
CAS:<p>PD-1/PD-L1-IN 5 is a potent PD-1/PD-L1 protein/protein interaction inhibitor (IC50 ≤ 100 nM).</p>Formula:C22H18N4O3SColore e forma:SolidPeso molecolare:418.47RDR03871
CAS:<p>RDR03871 is an MDM2 inhibitor.</p>Formula:C18H16ClF3N6Purezza:97.78%Colore e forma:SolidPeso molecolare:408.81

