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Apoptosi

Apoptosi

Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.

Sottocategorie di "Apoptosi"

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Trovati 5622 prodotti di "Apoptosi"

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  • Quinidine polygalacturonate

    CAS:
    Quinidine polygalacturonate: oral cytochrome P450db inhibitor, K+ channel blocker (IC50 19.9 μM), induces apoptosis, anti-arrhythmic, aids malaria research.
    Formula:C26H34N2O9
    Colore e forma:Solid
    Peso molecolare:518.22643
  • ZT55

    CAS:
    <p>ZT55: Oral JAK2 inhibitor, IC50: 0.031 μM, hinders JAK2 V617F HEL cell growth, induces apoptosis, arrests cell cycle, effective in mice HEL tumor studies.</p>
    Formula:C17H16N2O3
    Colore e forma:Solid
    Peso molecolare:296.32
  • DMH2

    CAS:
    <p>DMH2 is an antagonist of bone morphogenetic protein (BMP) type I receptor. It acts by decreasing growth and inducing cell death of lung cancer cell lines.</p>
    Formula:C27H25N5O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:451.52
  • CDK/HDAC-IN-2

    CAS:
    <p>CDK/HDAC-IN-2 inhibits HDAC1,2,3, CDK1,2, induces G2/M arrest, apoptosis, and shows anti-tumor effects.</p>
    Formula:C25H20Cl2N6O3
    Colore e forma:Solid
    Peso molecolare:523.37
  • Anticancer agent 42

    CAS:
    <p>Oral anticancer 42 targets MDA-MB-231 cells; IC50 0.07μM; triggers apoptosis, enhances p53. Useful for metastatic breast cancer study.</p>
    Formula:C19H16Cl2N2O3
    Colore e forma:Solid
    Peso molecolare:391.25
  • Anticancer agent 56

    CAS:
    <p>Anticancer agent 56 (4d) has potent action &lt;3μM IC50 on various cancers, causing G2/M arrest and mitochondrial apoptosis via ROS and caspase activation.</p>
    Formula:C20H18ClN3O3
    Colore e forma:Solid
    Peso molecolare:383.83
  • (S)-Erypoegin K

    CAS:
    <p>(S)-Erypoegin K is a potent anticancer agent that demonstrates strong anti-proliferative activity against HL-60 cells and induces apoptosis.</p>
    Formula:C20H18O6
    Colore e forma:Solid
    Peso molecolare:354.35
  • (Rac)-Indoximod

    CAS:
    <p>(Rac)-Indoximod, a robust IDO inhibitor, and IFN-γ combo reduce α-SMA hCM activity and boost apoptosis, aiding cardiac fibrosis.</p>
    Formula:C12H14N2O2
    Colore e forma:Solid
    Peso molecolare:218.25
  • AG311

    CAS:
    <p>AG311 inhibits complex I; destabilizes HIF-1α; triggers necrosis in cancer cells, mitochondrial depolarization, superoxide, and calcium increase.</p>
    Formula:C17H15N5S
    Colore e forma:Solid
    Peso molecolare:321.4
  • Antiproliferative agent-11


    <p>Antiproliferative agent-11, a Ruthenium(II) complex, targets multiple cancers with IC50s of 6-10 μM.</p>
    Formula:C31H34Cl2N6O3P2Ru
    Colore e forma:Solid
    Peso molecolare:772.56
  • CGP 65015

    CAS:
    <p>CGP 65015 is an oral iron chelator and can mobilize iron deposits.</p>
    Formula:C14H15NO4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:261.27
  • PHM16

    CAS:
    <p>PHM16 is an ATP competitive FAK and FGFR2 inhibitor.</p>
    Formula:C20H22N6O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:410.43
  • ARN 14494

    CAS:
    <p>ARN 14494, a potent SPT inhibitor (IC50=27.3 nM), reduces ceramide synthesis and neuroinflammation, and protects against β-amyloid toxicity.</p>
    Formula:C24H32N4O3
    Colore e forma:Solid
    Peso molecolare:424.54
  • PARP1/BRD4-IN-1

    CAS:
    <p>PARP1/BRD4-IN-1 selectively inhibits PARP1 (49 nM IC50) and BRD4 (202 nM IC50), hindering pancreatic cancer cell growth.</p>
    Formula:C29H26N6O3
    Colore e forma:Solid
    Peso molecolare:506.56
  • Apogossypolone (ApoG2)

    CAS:
    <p>Apogossypolone (ApoG2) is a semi-synthesized derivative of gossypol which is a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins with K i</p>
    Formula:C28H26O8
    Colore e forma:Solid
    Peso molecolare:490.5
  • RIPK1-IN-11

    CAS:
    <p>RIPK1-IN-11, an oral RIPK1 blocker, Kd 9.2 nM, IC50 67 nM, prevents necrosis and inflammation in cells.</p>
    Formula:C23H24N4O4S
    Colore e forma:Solid
    Peso molecolare:452.53
  • ISC-4

    CAS:
    <p>ISC-4 is an Akt inhibitor, which activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model.</p>
    Formula:C11H13NSe
    Colore e forma:Solid
    Peso molecolare:238.19
  • DRAK1/2-IN-1

    CAS:
    <p>DRAK1/2-IN-1 is a potent inhibitor targeting both DRAK1 and DRAK2, displaying dissociation constants (Kd) of 1 µM and 6 µM, respectively.</p>
    Formula:C22H24N2O3S
    Colore e forma:Solid
    Peso molecolare:396.5
  • PD-1/PD-L1-IN 5

    CAS:
    <p>PD-1/PD-L1-IN 5 is a potent PD-1/PD-L1 protein/protein interaction inhibitor (IC50 ≤ 100 nM).</p>
    Formula:C22H18N4O3S
    Colore e forma:Solid
    Peso molecolare:418.47
  • RDR03871

    CAS:
    <p>RDR03871 is an MDM2 inhibitor.</p>
    Formula:C18H16ClF3N6
    Purezza:97.78%
    Colore e forma:Solid
    Peso molecolare:408.81