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Apoptosi

Apoptosi

Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.

Sottocategorie di "Apoptosi"

Mostrare 6 più sottocategorie

Trovati 5598 prodotti di "Apoptosi"

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  • NiCur
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    NiCur

    CAS:
    <p>NiCur is an effective and selective inhibitor of CBP histone acetyltransferase (HAT), with an IC50 of 0.35 μM.</p>
    Formula:C22H16N2O
    Purezza:99.22%
    Colore e forma:Solid
    Peso molecolare:324.38

    Ref: TM-T60888

  • BMS-751324
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    BMS-751324

    CAS:
    <p>BMS-751324: p38α MAPK inhibitor with carbamyl-methyl, esters, phosphate from HPA. Reduces rat arthritis swelling and TNFα.</p>
    Formula:C32H35N6O10P
    Colore e forma:Solid
    Peso molecolare:694.63

    Ref: TM-T68266

  • Lonitoclax
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    Lonitoclax

    CAS:
    <p>Lonitoclax is an inhibitor of B-cell lymphoma 2 (Bcl-2). It demonstrates antitumor activity in B-cell and myeloid malignancy models comparable to Venetoclax. Lonitoclax holds potential for research in relapsed or refractory chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma, and certain low-grade lymphomas.</p>
    Formula:C43H45ClN4O5
    Colore e forma:Solid
    Peso molecolare:733.294

    Ref: TM-T205747

  • Apoptosis inducer 5
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    Apoptosis inducer 5

    <p>Apoptosis Inducer 5, a lignan enantiomer extracted from Crataegus pinnatifida, demonstrates cytotoxic properties through inducing apoptosis and autophagy in</p>
    Formula:C23H26O7
    Colore e forma:Solid
    Peso molecolare:414.45

    Ref: TM-T72509

  • EGFR/VEGFR2-IN-3
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    EGFR/VEGFR2-IN-3

    CAS:
    <p>EGFR/VEGFR2-IN-3 (compound 9) is an effective inhibitor of EGFR and VEGFR-2, demonstrating IC50 values of 0.129 µM for EGFR, 0.142 µM for VEGFR-2, and 3.428 µM for COX-2. This compound exhibits cytotoxic properties and induces cell apoptosis (apoptosis) as well as cell cycle arrest at the G2/M phase.</p>
    Formula:C24H20ClN5O2S2
    Colore e forma:Solid
    Peso molecolare:510.03

    Ref: TM-T201562

  • GPD-1116
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    GPD-1116

    CAS:
    <p>GPD-1116 is an orally active inhibitor of phosphodiesterase (PDE)4 and PDE1. The compound effectively reduces smoke-induced apoptosis in lung cells. Additionally, GPD-1116 has shown efficacy in various animal disease models, including emphysema, acute lung injury, chronic obstructive pulmonary disease (COPD), asthma, and pulmonary arterial hypertension.</p>
    Formula:C22H16N4O
    Colore e forma:Solid
    Peso molecolare:352.39

    Ref: TM-T201696

  • Aeroplysinin 1
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    Aeroplysinin 1

    CAS:
    <p>Aeroplysinin I is an antibacterial compound from the sponge. It has cytotoxic activity against colon cancer cells by promoting β-catenin degradation.</p>
    Formula:C9H9Br2NO3
    Colore e forma:Solid
    Peso molecolare:338.98

    Ref: TM-T23645

  • CIL-102
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    CIL-102

    CAS:
    <p>CIL-102 is an apoptosis inducer that functions as an MMP-2/MMP-9 inhibitor, effectively reducing both the protein expression and mRNA levels of MMP-2/MMP-9. CIL-102 also demonstrates anticancer activity.</p>
    Formula:C19H14N2O2
    Colore e forma:Solid
    Peso molecolare:302.327

    Ref: TM-T204649

  • PF-3837
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    PF-3837

    CAS:
    <p>PF-3837 is an inhibitor of the Mps1 kinase, with a Ki value of 0.33 nM and an IC50 value of 5.5 nM. It disrupts cell cycle checkpoints by inhibiting the catalytic activity of Mps1, thereby reducing genomic stability and leading to cancer cell apoptosis (Apoptosis). PF-3837 is utilized in the study of breast cancer.</p>
    Formula:C21H26N8O2
    Colore e forma:Solid
    Peso molecolare:422.48

    Ref: TM-T200061

  • GNE684
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    GNE684

    CAS:
    <p>GNE684 inhibits RIP1; Ki app: 21 nM (human), 189 nM (mouse), 691 nM (rat).</p>
    Formula:C23H24N6O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:432.48

    Ref: TM-T11442

  • GLUT-1-IN-4
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    GLUT-1-IN-4

    CAS:
    <p>GLUT-1-IN-4 (Compound 13) is an inhibitor of the GLUT-1 glucose transporter that depends on the p53 protein. It suppresses the proliferation of various cancer cells at submicromolar IC50 levels. Additionally, GLUT-1-IN-4 can halt the cell cycle, induce oxidative stress, and promote apoptosis (cell death).</p>
    Formula:C15H10N2O3
    Colore e forma:Solid
    Peso molecolare:266.251

    Ref: TM-T204565

  • WYJ-2
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    WYJ-2

    CAS:
    <p>WYJ-2, a selective agonist for toll-like receptor 2/1 (TLR2/1), demonstrates an EC50 of 18.57 nM in HEK 293T cells transiently co-transfected with human TLR2 and TLR1. It induces pyroptosis and has shown anticancer activity against non-small cell lung cancer (NSCLC) [1].</p>
    Formula:C17H9F2N3O4
    Colore e forma:Solid
    Peso molecolare:357.27

    Ref: TM-T87637

  • Topoisomerase inhibitor 4
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    Topoisomerase inhibitor 4

    CAS:
    <p>Topoisomerase inhibitor4 (compound 45) acts as an effective inhibitor of Topoisomerase1/2, arresting the cell cycle at the G2/M phase and inducing Apoptosis. This compound exhibits potent antitumor activity.</p>
    Formula:C30H28F3IN4O3
    Colore e forma:Solid
    Peso molecolare:676.47

    Ref: TM-T200556

  • Logo CymitQuimica
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    XPO1-IN-1

    <p>XPO1-IN-1: an oral MM.1S cell inhibitor (IC50: 24 nM), induces apoptosis, stable metabolism, good pharmacokinetics.</p>
    Formula:C20H15F6N5O3S
    Colore e forma:Solid
    Peso molecolare:519.42

    Ref: TM-T63623

  • CP-31398
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    CP-31398

    CAS:
    <p>CP-31398 stabilizes the active conformation of p53 in cancer cells with either mutated or wild-type p53, enhancing its activity. Additionally, CP-31398 upregulates target genes of p53 such as p21WAF1/Cip1 and KILLER/DR5. This compound possesses tumor-suppressive properties.</p>
    Formula:C22H26N4O
    Colore e forma:Solid
    Peso molecolare:362.47

    Ref: TM-T201533

  • Samuraciclib
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    Samuraciclib

    CAS:
    <p>Samuraciclib (CT7001) is an oral CDK7 inhibitor with 41 nM IC50, notable for its high selectivity and potency against breast cancer cells.</p>
    Formula:C22H30N6O
    Colore e forma:Solid
    Peso molecolare:394.51

    Ref: TM-T61835

  • PI4KIII β inhibitor 4
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    PI4KIII β inhibitor 4

    CAS:
    <p>PI4KIII beta inhibitor 4 (Compound 16) is a selective inhibitor of PI4KIIIβ with an IC50 of 0.005 μM. By inhibiting the PI3K/AKT pathway, PI4KIII beta inhibitor 4 induces apoptosis, causes cell cycle arrest, and triggers autophagy in tumor cells. This compound is applicable for tumor research.</p>
    Formula:C24H36N4O6S2
    Colore e forma:Solid
    Peso molecolare:540.696

    Ref: TM-T206216

  • Sampangine
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    Sampangine

    CAS:
    <p>Sampangine, an alkaloid, induces apoptosis by causing cell cycle arrest at the G0/G1 phase and inhibits the biosynthesis of heme.</p>
    Formula:C15H8N2O
    Colore e forma:Solid
    Peso molecolare:232.24

    Ref: TM-T200281

  • SLCB050
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    SLCB050

    CAS:
    <p>SLCB050 is a compound with anticancer activity that inhibits the interaction between DX2 and p14/ARF. It decreases the viability of human lung cancer cells, particularly small cell lung cancer cells, in a p14/ARF-dependent manner, and induces cell apoptosis (apoptosis) and senescence.</p>
    Formula:C21H18O6
    Colore e forma:Solid
    Peso molecolare:366.36

    Ref: TM-T200005

  • Logo CymitQuimica
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    Anticancer agent 44

    <p>Anticancer agent 44 induces apoptosis, is selective, cytotoxic to cancer cells, and minimally toxic to human lymphocytes.</p>
    Formula:C22H13Cl2N3O5S2
    Colore e forma:Solid
    Peso molecolare:534.39

    Ref: TM-T63759