Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(11 prodotti)
- Caspasi(144 prodotti)
- FOXO1(3 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(139 prodotti)
- PDK(9 prodotti)
- PERK(26 prodotti)
- Chinasi di serina/treonina(18 prodotti)
- Survivin(14 prodotti)
- TNF(93 prodotti)
- c-RET(62 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 6070 prodotti di "Apoptosi"
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Polyinosinic-polycytidylic acid potassium
CAS:Poly(I:C) potassium is a synthetic RNA analog, activates TLR3/RIG-I, used as a vaccine adjuvant, and induces apoptosis in cancer cells.Formula:(C10H13N4O8P)x·(C9H14N3O8P)x·xKColore e forma:SolidXIAP BIR2/BIR2-3 inhibitor-3
CAS:XIAP BIR2/BIR2-3 Inhibitor-3 functions as a dual inhibitor targeting both BIR2 and BIR2-3 domains, exhibiting potent activity with IC50 values below 1 nM. This compound is utilized in cancer research [1].Formula:C86H106N18O16S2Colore e forma:SolidPeso molecolare:1712Danburstotug
CAS:Danburstotug (IMC-001), an immunostimulant and antineoplastic [1], is a humanized IgG1-lambda monoclonal antibody targeting CD274 (PDL1, B7 homologue 1, B7H1).Purezza:98%Colore e forma:LiquidASK1-IN-4
CAS:ASK1-IN-4 is an ASK1 inhibitor, IC50 = 0.2 μM.Formula:C18H14BrNO4S2Purezza:99.756%Colore e forma:SolidPeso molecolare:452.34Atibuclimab
CAS:Atibuclimab is a chimeric monoclonal antibody targeting CD14, consisting of a mouse variable region and a human IgG4 Fc region.Purezza:> 95% - > 95%Colore e forma:LiquidPeso molecolare:145.28 kDaGSK-1070916
CAS:GSK-1070916 (GSK-1070916A) is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM.Formula:C30H33N7OPurezza:99.73%Colore e forma:SolidPeso molecolare:507.63RLX HCl
CAS:RLX HCl is anticancer, inhibits tumour proliferation by suppressing the PI3K/Akt/FoxO3a in experimental colon cancer, antiproliferative.Formula:C13H15ClN2OPurezza:99.43%Colore e forma:SoildPeso molecolare:250.72Ref: TM-T24715L
1mg201,00€5mg497,00€10mg700,00€25mg1.094,00€50mg1.508,00€100mg1.922,00€200mg2.627,00€4-Nitrothalidomide
CAS:4-Nitrothalidomide is a modified form of thalidomide that inhibits the growth and proliferation of HUVEC cells and is commonly used in the synthesis of pomalidomide, which has anticancer potential.Formula:C13H9N3O6Purezza:99.94%Colore e forma:SolidPeso molecolare:303.23p-MPPF
CAS:p-MPPF is a 5-HT antagonist that can be used to study neurological diseases.Formula:C25H27FN4O2Purezza:99.92%Colore e forma:SolidPeso molecolare:434.51CIGB-300
CAS:CIGB-300 (P15-Tat) is an anti-casein kinase 2 (CK2) peptide that exhibits anticancer properties by disrupting the phosphorylation activity of protein kinase CK2. The compound induces apoptosis in various tumor cell lines, making it valuable for research in cancer therapy.Formula:C127H215N53O30S3Colore e forma:SolidPeso molecolare:3060.6Thalidomide-5-NH-PEG2-NH2 hydrochloride
CAS:Thalidomide-5-NH-PEG2-NH2 hydrochloride is a cereblon ligand based on Thalidomide, designed to recruit CRBN proteins. It has the capability to be linked with target protein ligands via a linker, facilitating the formation of PROTAC molecules, such as THAL-SNS-032.Formula:C19H25ClN4O6Colore e forma:SolidPeso molecolare:440.88MMRi62
CAS:MMRi62, a MDM2-MDM4 inhibitor, induces ferroptosis and autophagy in PDAC, degrades FTH1 and mutant p53, and inhibits KRAS/TP53 mutant PDAC in mice.Formula:C21H15Cl2N3OPurezza:99.87%Colore e forma:SoildPeso molecolare:396.27Ref: TM-T60202
1mg35,00€5mg70,00€10mg104,00€25mg202,00€50mg329,00€100mg525,00€500mg1.121,00€1mL*10mM (DMSO)78,00€Retifanlimab
CAS:Retifanlimab (MGA-012) is a monoclonal antibody targeting programmed cell death protein 1 (PD-1). Retifanlimab is used in studies of Merkel cell carcinoma.Purezza:98.56% (SEC-HPLC) - >95.0% (SDS-PAGE); 100% (SEC-HPLC)Colore e forma:LiquidPacmilimab
CAS:Pacmilimab (CX-072) is a Probody immune checkpoint inhibitor targeting programmed death ligand 1 (PD-L1) with anti-tumor activity for the study of solid tumors.Purezza:98.8% (SDS-PAGE); 96.3% (SEC-HPLC) - 98.8% (SDS-PAGE); 96.3% (SEC-HPLC)Colore e forma:LiquidLatikafusp
CAS:Latikafusp (AMG 256) is a fusion protein that is a PD-1 blocker and IL-21R agonist with antitumor activity.Purezza:97.1% (SDS-PAGE); 97.4% (SEC-HPLC) - 97.1% (SDS-PAGE); 97.4% (SEC-HPLC)Colore e forma:LiquidAc-Trp-Glu-His-Asp-Aldehyde
CAS:Ac-Trp-Glu-His-Asp-Aldehyde is a powerful and selective inhibitor of caspase-1, demonstrating a K_i value of 56 pM [1] [2].Formula:C28H33N7O9Colore e forma:SolidPeso molecolare:611.6PTD-p65-P1 Peptide TFA
<p>Ptd-p65-p1 Peptide TFA inhibits NF-kappaB, has a cell-penetrating antennapedia sequence, and selectively blocks NF-kappaB activation.</p>Formula:C170H276F3N57O46SPurezza:98%Colore e forma:SolidPeso molecolare:3943.52Tubulin inhibitor 34
Tubulin Inhibitor 34 (compound b5), a potent anticancer agent, inhibits tubulin polymerization and induces G2/M arrest and apoptosis.Formula:C21H22N4O3SColore e forma:SolidPeso molecolare:410.49UZH1
CAS:UZH1, a mix of active METTL3 inhibitor UZH1a (IC50 280 nM) and inactive UZH1b (IC50 28 μM), modifies epitranscriptomics and has antitumor properties.Formula:C32H42N6O3Colore e forma:SoildPeso molecolare:558.71IRF1-IN-2
CAS:IRF1-IN-2 is a small molecule IRF1 inhibitor that suppresses pyroptosis, protecting against radiation-induced skin damage.Formula:C18H20N2O4SPurezza:99.85%Colore e forma:SolidPeso molecolare:360.43
