Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(1 prodotti)
- Caspasi(154 prodotti)
- FOXO1(2 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(137 prodotti)
- PDK(9 prodotti)
- PERK(23 prodotti)
- Chinasi di serina/treonina(18 prodotti)
- Survivin(14 prodotti)
- TNF(94 prodotti)
- c-RET(61 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 6231 prodotti di "Apoptosi"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Opnurasib
CAS:Opnurasib (JDQ-443) is an orally available and selective and potent covalent KRAS G12C inhibitor with antitumor activity for the study of advanced non-smallFormula:C29H28ClN7OPurezza:98.88%Colore e forma:SolidPeso molecolare:526.03Ref: TM-T40292
50mgPrezzo su richiesta1mg100,00€5mg334,00€1mL*10mM (DMSO)385,00€10mg500,00€25mg803,00€Apoptosis inducer 32
Apoptosisinducer 32 (Compound 7g) is an apoptosis inducer with a KD of 42 μM, demonstrating antitumor activity by causing significant morphological changes, such as membrane blebbing, nuclear fragmentation, and apoptotic body formation, in MDA-MB-231 cells. The IC50 values for Apoptosisinducer 32 are 4.77 μM in MCF-7 cells, 6.56 μM in MDA-MB-231 cells, and 337.8 μM in HEK cells.Formula:C29H27Cl2N3O8Colore e forma:SolidPeso molecolare:616.45MPP hydrochloride
MPP hydrochloride is a selective estrogen receptor (ERR) modulator.Formula:C29H32ClN3O3Purezza:99.75% - 99.90%Colore e forma:SolidPeso molecolare:506.04Ref: TM-T21897L
1mg50,00€5mg99,00€1mL*10mM (DMSO)110,00€10mg160,00€25mg313,00€50mg528,00€100mg707,00€200mg973,00€WR-S-462
WR-S-462 is a STAT3 inhibitor. It effectively blocks the phosphorylation and biological functions of STAT3 in vitro. The IC50 of WR-S-462 for inhibiting MDA-MB-231 cells is 0.03 μM, and it exhibits a strong binding affinity for STAT3 protein with a Kd of 58 nM. WR-S-462 prevents the nuclear translocation of p-STAT3 and selectively inhibits the expression of p-STAT3Tyr705 in MDA-MB-231 cells, as well as the expression of downstream target genes regulated by STAT3, such as Cyclin D1, Bcl-2, and Bcl-xl. This compound inhibits the growth and metastasis of triple-negative breast cancer (TNBC).Formula:C24H22N4O4SColore e forma:SolidPeso molecolare:462.52FR900359
CAS:FR900359 is a macrocyclic Gq protein inhibitor that inhibits melanoma cell proliferation and can be used to study asthma, inflammation and cancer.Formula:C49H75N7O15Purezza:98%Colore e forma:SolidPeso molecolare:1002.16EGFR/COX-2-IN-1
EGFR/COX-2-IN-1 is an EGFR/COX-2 inhibitor that effectively targets EGFRWT, EGFRT790M, COX-1, and COX-2 with IC50 values of 0.12, 0.076, 20.1, and 1.52 μM, respectively. It inhibits MCF-7, HT-29, and A-549 cells with IC50 values of 1.20, 5.14, and 14.81 μM, respectively. The compound induces apoptosis by upregulating Bax protein and downregulating Bcl-2 protein levels. Additionally, EGFR/COX-2-IN-1 significantly increases the proportion of cells in the G2/M phase in MCF-7 cells, demonstrating a broad-spectrum antitumor effect.Formula:C20H17FN6O2S2Colore e forma:SolidPeso molecolare:456.52GSK-3β inhibitor 15
GSK-3β inhibitor 15 (Compound 54), with an IC50 of 3.4 nM, effectively suppresses Aβ 1-42-induced phosphorylation of GSK-3β and tau protein, as well as LPS-Formula:C17H16N6OSColore e forma:SolidPeso molecolare:352.41HDAC3-IN-2
HDAC3-IN-2 (compound 4i), a pyrazinyl hydrazide-based HDAC3 inhibitor with an IC50 of 14 nM, effectively targets triple-negative breast cancer cells.Formula:C16H21N5O2Purezza:98%Colore e forma:SolidPeso molecolare:315.37Anti-Mouse PD-1 (LALA-PG) Antibody (RMP1-14)
Anti-MousePD-1(LALA-PG) Antibody (RMP1-14) is an IgG2a, κ antibody inhibitor derived from mice that targets and inhibits mouse PD-1.Colore e forma:Odour LiquidAc-LEHD-AMC
CAS:Ac-LEHD-AMC, a fluorogenic caspase-9 substrate, releases fluorescent AMC upon cleavage, aiding caspase-9 activity measurement.Formula:C33H41N7O11Colore e forma:SolidPeso molecolare:711.729N-Deshydroxyethyl Dasatinib
CAS:N-Deshydroxyethyl Dasatinib (N-Deshydroxyethyl BMS-354825) is a metabolite of Dasatinib, a dasatinib-based molecule that degrades ABL by binding to the IAPFormula:C20H22ClN7OSPurezza:95.96%Colore e forma:SolidPeso molecolare:443.95Ref: TM-T18750
1mg52,00€5mg111,00€1mL*10mM (DMSO)127,00€10mg170,00€25mg294,00€50mg425,00€100mg583,00€200mg790,00€E3 ligase Ligand 36
CAS:E3 ligase Ligand 36 is an E3 ligase ligand that can be utilized for synthesizing PROTACs, such as PROTAC BRM/BRG1 degrader-1.Formula:C25H30N4O5SColore e forma:SolidPeso molecolare:498.6Baceridin
CAS:Baceridin, a cyclic hexapeptide and proteasome inhibitor, can be isolated from the culture medium of Epiphytic Bacillus.Formula:C37H57N7O6Purezza:98%Colore e forma:SolidPeso molecolare:695.89MPT0B014
CAS:MPT0B014 is a potent tubulin polymerization inhibitor. MPT0B014 can induce cancer cell apoptosis.
Formula:C19H17NO4Purezza:99.52%Colore e forma:SolidPeso molecolare:323.34Jacaric Acid
CAS:Conjugated 18-C ω-6 fatty acid from Jacaranda seeds, induces cancer cell apoptosis via oxidative stress; metabolizes to cytotoxic CLA.Formula:C18H30O2Colore e forma:SolidPeso molecolare:278.436EGFR-IN-83
EGFR-IN-83 (Compound 9), an EGFR inhibitor with an IC50 of 2.53 nM, exhibits antiproliferative effects on MCF-7 and MDA-MB-231 cell lines, with respective IC50Formula:C22H17F3N4OPurezza:98%Colore e forma:SolidPeso molecolare:410.39Narasin
CAS:Narasin inhibits dengue virus, treats coccidiosis without harm to cells, and induces cancer cell apoptosis.Formula:C43H72O11Colore e forma:SolidPeso molecolare:765.03DRI-C21041 (DIEA)
DRI-C21041 DIEA serves as an inhibitor of CD40/CD40L interaction, exhibiting an inhibitory concentration (IC50) of 0.31 μM.Formula:C38H40N4O7SColore e forma:SolidPeso molecolare:696.81MKC-1
CAS:MKC-1 (Ro-31-7453) is an oral bisindolylmaleimide inhibitor that disrupts tubulin polymerization, potentially halting cancer cell division.Formula:C22H16N4O4Purezza:99.63% - 99.85%Colore e forma:SolidPeso molecolare:400.39Ref: TM-T9831
500mgPrezzo su richiesta1mg54,00€5mg118,00€1mL*10mM (DMSO)127,00€10mg168,00€25mg293,00€50mg423,00€100mg588,00€Pantinin-1
CAS:Pantinin-1 is an antimicrobial peptide found in the venom of the emperor scorpion (Pandinus imperator). This compound exhibits strong antibacterial activity against Gram-positive bacteria and fungi, but has weaker effects on Gram-negative bacteria. Additionally, Pantinin-1 demonstrates very low hemolytic activity on human red blood cells and possesses anticancer properties, specifically inducing apoptosis in tumor cells.Formula:C75H119N17O18Colore e forma:SolidPeso molecolare:1546.85
