Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(6 prodotti)
- BCL(11 prodotti)
- Caspasi(127 prodotti)
- FOXO1(3 prodotti)
- IAP(65 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(126 prodotti)
- PDK(9 prodotti)
- PERK(24 prodotti)
- Chinasi di serina/treonina(15 prodotti)
- Survivin(13 prodotti)
- TNF(91 prodotti)
- c-RET(51 prodotti)
- p53(62 prodotti)
Mostrare 6 più sottocategorie
Trovati 5622 prodotti di "Apoptosi"
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Pravastatin sodium
CAS:<p>Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.</p>Formula:C23H35NaO7Purezza:97.14%Colore e forma:White Crystalline PowderPeso molecolare:446.52GCN2iB
CAS:<p>GCN2iB is an ATP-competitive inhibitor of serine/threonine protein kinase, stress-responsive kinase (GCN2).Cost-effective and quality-assured.</p>Formula:C18H12ClF2N5O3SPurezza:99.08%Colore e forma:SolidPeso molecolare:451.83Ligandrol
CAS:<p>Ligandrol is a novel nonsteroidal, oral SARM that binds to the androgen receptor with high affinity (Ki: 1 nM) and selectivity.</p>Formula:C14H12F6N2OPurezza:99.94% - >99.99%Colore e forma:SolidPeso molecolare:338.25Dipyridamole
CAS:Dipyridamole (Persantin) is a Platelet Aggregation Inhibitor. The physiologic effect of dipyridamole is by means of Decreased Platelet Aggregation.Formula:C24H40N8O4Purezza:99.47% - 99.84%Colore e forma:SolidPeso molecolare:504.63Proadifen hydrochloride
CAS:<p>Proadifen hydrochloride (RP-5171) is an inhibitor of drug metabolism and cytochrome P-450 enzyme system activity.</p>Formula:C23H32ClNO2Purezza:99.84% - >99.99%Colore e forma:SolidPeso molecolare:389.96Methazolamide
CAS:<p>Methazolamide (CL 8490) is a carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.</p>Formula:C5H8N4O3S2Purezza:99.31% - 99.77%Colore e forma:Crystals From Water SolidPeso molecolare:236.27Hexamethonium Bromide
CAS:<p>Hexamethonium Bromide blocks neural nicotinic AChR, poorly absorbed in the gut, doesn't pass the blood-brain barrier.</p>Formula:C12H30Br2N2Purezza:99.76%Colore e forma:White Crystalline Powder And AgglomeratesPeso molecolare:362.19Sodium 4-phenylbutyrate
CAS:<p>Sodium 4-phenylbutyrate (TriButyrate), a transcriptional regulator, reversibly inhibits class I and II HDACs resulting in a global increase in gene expression.</p>Formula:C10H11NaO2Purezza:99.02% - >99.99%Colore e forma:SolidPeso molecolare:186.18Mitoxantrone dihydrochloride
CAS:<p>Mitoxantrone dihydrochloride (NSC-301739) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone is a type II topoisomerase inhibitor.</p>Formula:C22H30Cl2N4O6Purezza:97.05% - >99.99%Colore e forma:Blue-Black Solid From Water Ethanol SolidPeso molecolare:517.4Xanthurenic Acid
CAS:<p>Xanthurenic Acid (8-Hydroxykynurenic acid), a molecule arising from tryptophan metabolism by transamination of 3-hydroxykynurenine.</p>Formula:C10H7NO4Purezza:93.54% - 99.66%Colore e forma:SolidPeso molecolare:205.17Levetiracetam
CAS:<p>Levetiracetam (SIB-S1) is a relatively unique anticonvulsant that is typically used in combination with other antiepileptic medications for partial onset</p>Formula:C8H14N2O2Purezza:99.67% - 99.86%Colore e forma:White Crystalline PowderPeso molecolare:170.21Tetraethylenepentamine Pentahydrochloride
CAS:<p>Tetraethylenepentamine Pentahydrochloride is a high affinity copper and zinc chelator.</p>Formula:C8H23N5·5HClPurezza:≥95%Colore e forma:SolidPeso molecolare:371.612H-Indol-2-one, 3-[1,3-dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-
CAS:Formula:C16H11N3O2Purezza:98%Colore e forma:SolidPeso molecolare:277.2774Teneliximab
CAS:<p>Teneliximab (BMS 224819) is a chimeric monoclonal antibody that blocks CD40-CD40L interactions.Cost-effective and quality-assured.</p>Purezza:95.00% - 99.19% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:146.06 kDaKetoprofen
CAS:<p>Ketoprofen (RP-19583) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects.</p>Formula:C16H14O3Purezza:99.67% - 99.97%Colore e forma:SolidPeso molecolare:254.28Lenalidomide
CAS:<p>Lenalidomide (CC-5013) is an orally immunomodulator. Lenalidomide is a ligand for the ubiquitin E3 ligase cereblon (CRBN). Cost-effective and quality-assured.</p>Formula:C13H13N3O3Purezza:98% - 99.97%Colore e forma:Yellow SolidPeso molecolare:259.26Iproniazid Phosphate
CAS:<p>Iproniazid Phosphate is a non-selective, irreversible monoamine oxidase inhibitor (MAOI).</p>Formula:C9H13N3O·H3PO4Purezza:99.6% - 99.87%Colore e forma:SolidPeso molecolare:277.21Topotecan hydrochloride
CAS:<p>Topotecan hydrochloride (NSC609699) is an antineoplastic agent used to treat ovarian cancer.</p>Formula:C23H24ClN3O5Purezza:97.88% - 99.41%Colore e forma:White Crystalline SolidPeso molecolare:457.92GPI-1046
CAS:<p>GPI-1046: immunophilin ligand, no antibiotic effect, reduces ethanol intake by boosting GLT1 in PFC and NAc-core.</p>Formula:C20H28N2O4Purezza:99.69%Colore e forma:SolidPeso molecolare:360.45Emamectin Benzoate
CAS:<p>Emamectin Benzoate (MK-244), by binding gamma-aminobutyric acid (GABA) receptor and glutamate-gated chloride channels disrupting nerve signals within arthropods</p>Formula:C56H81NO15Purezza:98.68%Colore e forma:SolidPeso molecolare:1008.256Bromelain
CAS:<p>Bromelain, from pineapple stem, is an anti-inflammatory that modulates kininogen, AGE receptors, PGE2, angiogenesis, and has antioxidant COX-pathway effects.</p>Formula:C39H66N2O29Purezza:98%Colore e forma:SolidPeso molecolare:1026.942Cusatuzumab
CAS:<p>Cusatuzumab (ARGX-110) is a human CD70 monoclonal antibody with enhanced antibody-dependent cytotoxic activity.</p>Purezza:95% - 95%Colore e forma:LiquidPhenol, 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-
CAS:Formula:C18H20O5Purezza:98%Colore e forma:SolidPeso molecolare:316.3484Chlorzoxazone
CAS:Chlorzoxazone (Chlorzoxazon) is a Muscle Relaxant. The physiologic effect of chlorzoxazone is by means of Centrally-mediated Muscle Relaxation.Formula:C7H4ClNO2Purezza:99.49% - 99.6%Colore e forma:SolidPeso molecolare:169.57NVS-ZP7-4
CAS:<p>NVS-ZP7-4 is a inhibitor of Zinc transporter SLC39A7 (ZIP7).</p>Formula:C28H28FN5OSPurezza:99.86%Colore e forma:SolidPeso molecolare:501.62Bromoiodoacetamide
CAS:<p>Bromoiodoacetamide (I-HAcAm): cytotoxic, induces ROS & apoptosis in HepG-2 cells.</p>Formula:C2H3BrINOColore e forma:SolidPeso molecolare:263.86MS78
<p>MS78, an acetylation targeting chimera (AceTAC), specifically acetylates the p53Y220C mutant by recruiting the histone acetyltransferase p300/CBP.</p>Formula:C57H66FN9O6SColore e forma:SolidPeso molecolare:1024.25Ono 3403
CAS:<p>Ono 3403, a synthetic serine protease inhibitor, blocks TNF-alpha, NO production, and has antitumor properties.</p>Formula:C26H31N3O8SPurezza:98%Colore e forma:SolidPeso molecolare:545.6CNDAC hydrochloride
CAS:<p>CNDAC hydrochloride, a nucleoside analog, is a metabolite of the sapacitabine.</p>Formula:C10H13ClN4O4Purezza:99.45%Colore e forma:SolidPeso molecolare:288.69Urelumab
CAS:<p>"Urelumab (BMS-66513), a humanized IgG4 mAb CD137 agonist, boosts T-cell/NK cell-mediated cytotoxicity and anti-tumor activity."</p>Purezza:97.70%Colore e forma:LiquidPeso molecolare:145.90 kDaAPG-1387
CAS:<p>APG-1387 inhibits IAPs, degrades cIAP1/2, XIAP, boosts chemosensitivity, and induces apoptosis in NPC.</p>Formula:C60H72N10O10S2Colore e forma:SolidPeso molecolare:1157.41Lambertianic acid
CAS:<p>Lambertianic acid is a bioactive chemical that has anti-allergic and antibacterial effects.</p>Formula:C20H28O3Purezza:98%Colore e forma:SolidPeso molecolare:316.441Tralokinumab
CAS:<p>Tralokinumab: human IgG4 monoclonal antibody, blocks IL-13, may treat atopic dermatitis.</p>Purezza:SDS-PAGE:95% SEC-HPLC:99.99%Colore e forma:LiquidPeso molecolare:144.14 kDaeIF4A3-IN-7
CAS:<p>eIF4A3-IN-7: Potent eIF4A3 inhibitor, potential cancer/dysproliferation research (WO2019161345A1, Compound 8).</p>Formula:C26H25NO7Colore e forma:SolidPeso molecolare:463.486Bcl-2-IN-4
CAS:<p>Bcl-2-IN-4: potent, selective, oral Bcl-2 inhibitor with 1.5 nM IC50, >200x selectivity over Bcl-xL.</p>Formula:C46H50ClN9O7SColore e forma:SolidPeso molecolare:908.46PDE4D inhibitor 1
<p>PDE4-IN-1 is a PDE4 inhibitor characterized by high potency (IC50: 8.6 nM) and superior selectivity over other PDE subtypes. This compound inhibits the release of inflammatory cytokines and chemokines. Additionally, PDE4-IN-1 significantly restores the damaged cAMP-CREB signaling pathway, inhibits proliferation, and promotes differentiation to reverse psoriasis formation.</p>Colore e forma:Odour Solid5α-dihydro Levonorgestrel
CAS:<p>5α-dihydro Levonorgestrel is a metabolite of the synthetic progestin levonorgestrel .</p>Formula:C21H30O2Colore e forma:SolidPeso molecolare:314.469S65487 sulfate
CAS:<p>S65487 (VOB560) sulfate, a potent and selective Bcl-2 inhibitor, demonstrates activity against BCL-2 mutations, including G101V and D103Y.</p>Formula:C41H43ClN6O8SColore e forma:SolidPeso molecolare:815.34EMB-02
<p>EMB-02 is a bispecific antibody targeting both PD-1 and LAG-3. It inhibits the downregulation of T cell activation and proliferation mediated by PD-1 and LAG-3, showing potent anti-cancer properties.</p>Colore e forma:Odour LiquidKP1019
CAS:<p>KP1019 is now discontinued.</p>Formula:C21H19Cl4N6RuColore e forma:SolidPeso molecolare:598.30Sotigalimab
CAS:<p>Sotigalimab (APX 005) is a monoclonal antibody targeting CD40 with anticancer activity for the study of metastatic pancreatic cancer.</p>Purezza:98.50% - 98.50%Colore e forma:LiquidCot inhibitor-1 hydrochloride
<p>Cot inhibitor-1 hydrochloride blocks TPL-2 kinase (IC50=28nM) and TNF-α synthesis (IC50=5.7nM) in human blood.</p>Formula:C27H28Cl3FN8Purezza:98.26%Colore e forma:SoildPeso molecolare:589.92Thalidomide-O-PEG2-propargyl
CAS:<p>Thalidomide-O-PEG2-propargyl is a cereblon-based E3 ligase ligand with a PEG linker for PROTAC-induced protein degradation.</p>Formula:C20H20N2O7Purezza:98%Colore e forma:SolidPeso molecolare:400.38Thalidomide-NH-PEG4-COOH
CAS:<p>Thalidomide-NH-PEG4-COOH is a E3 ligase ligand-linker for synthesizing the selective degrader dCBP-1 targeting p300/CBP.</p>Formula:C24H31N3O10Colore e forma:SolidPeso molecolare:521.523PTD-p65-P1 Peptide
<p>PTD-p65-P1: a NF-kappaB inhibitor blocking activation from multiple inflammatory stimuli.</p>Formula:C168H275N57O44SPurezza:98%Colore e forma:SolidPeso molecolare:3829.5PL120131
<p>PL120131 is a PD-1/PD-L1 inhibitory peptide that disrupts the interaction between PD-1 and PD-L1 by binding to PD-1. This compound can inhibit the apoptosis signaling pathway mediated by PD-1, thereby preventing apoptosis (apoptosis) in Jurkat cells and primary lymphocytes. Additionally, PL120131 supports cytotoxic T lymphocytes (CTL) in exhibiting antitumor activity.</p>Formula:C62H105N19O18Colore e forma:SolidPeso molecolare:1404.61Fisetin quarterhydrate
<p>Fisetin quarterhydrate, a natural flavonol present in numerous fruits and vegetables, exhibits benefits including antioxidant, anticancer, and neuroprotective</p>Formula:C15H10O6H2OColore e forma:SolidPeso molecolare:304.0583Thalidomide-O-C4-COOH
CAS:<p>Thalidomide-O-C4-COOH is a synthetic E3 ligase linker derived from Thalidomide for PROTAC tech.</p>Formula:C18H18N2O7Colore e forma:SolidPeso molecolare:374.3447Lactoferrin (17-41)
CAS:<p>Amino acids 17-41 of lactoferrin, lactoferricin B, enhance anti-fungal effects, targeting Candida Albicans.</p>Formula:C141H224N46O29S3Purezza:98%Colore e forma:SolidPeso molecolare:3123.77Thalidomide-O-amido-C3-COOH
CAS:<p>Thalidomide-O-amido-C3-COOH is a cereblon ligand-linker for PROTACs, melding Thalidomide with a standard linker.</p>Formula:C19H19N3O8Purezza:98%Colore e forma:SolidPeso molecolare:417.37
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