Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(6 prodotti)
- BCL(11 prodotti)
- Caspasi(125 prodotti)
- FOXO1(3 prodotti)
- IAP(66 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(125 prodotti)
- PDK(9 prodotti)
- PERK(25 prodotti)
- Chinasi di serina/treonina(15 prodotti)
- Survivin(13 prodotti)
- TNF(92 prodotti)
- c-RET(51 prodotti)
- p53(62 prodotti)
Mostrare 6 più sottocategorie
Trovati 5593 prodotti di "Apoptosi"
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Ferroptosis-IN-1
<p>Ferroptosis-IN-1, a diterpene derived from A.</p>Formula:C22H34O5Purezza:98%Colore e forma:SolidPeso molecolare:378.5DJ4
CAS:<p>DJ4 induces a dose-dependent pro-apoptotic effect in the micromolar range.</p>Formula:C19H16N4OSPurezza:≥98%Colore e forma:SoildPeso molecolare:348.42Platycoside G3
CAS:<p>Platycoside G3 is a useful organic compound for research related to life sciences. The catalog number is T124100 and the CAS number is 849758-44-7.</p>Formula:C63H102O32Colore e forma:SolidPeso molecolare:1371.48TAT-BH4 (Bcl-xL)
<p>TAT-BH4 (Bcl-xL), primarily localized at the mitochondria, inhibits apoptotic cell death.</p>Formula:C159H268N58O45Purezza:98%Colore e forma:SolidPeso molecolare:3712.19Flaccidoside II
CAS:<p>Flaccidoside II, an active triterpenoid saponin from Anemone flaccida rhizome, both inhibits proliferation and induces apoptosis in Malignant Peripheral Nerve</p>Formula:C59H96O25Purezza:98%Colore e forma:SolidPeso molecolare:1205.38Apoptosis inducer 13
<p>Apoptosis Inducer 13 (Compound Ru4) promotes apoptosis in cancer cells while also suppressing their migration and invasion.</p>Formula:C59H54ClF6N8O4PRuPurezza:98%Colore e forma:SolidPeso molecolare:1220.6Anti-inflammatory agent 61
<p>Compound 5b (Anti-inflammatory agent 61) is a potent anti-inflammatory agent that diminishes TNF-α expression in LPS-induced inflammation within RAW 264.7 cells</p>Colore e forma:Odour SolidSe-Aspirin
CAS:<p>Se-Aspirin (Se-NSAID-8) has anticancer activity and gastroprotective effects, inhibits activation of proinflammatory and pro-survival NF-ĸB pathways, and inhibits the expression of anti-apoptotic targets downstream of NF-ĸB (e.g., Bcl-xL, Mcl-1, and survivin).Se-Aspirin induces Cell cycle arrest and activation of apoptosis accelerates ulcer healing and can be used to study pancreatic and colorectal cancer.</p>Formula:C12H12N2O3SePurezza:98.07%Colore e forma:SolidPeso molecolare:311.2Antitumor agent-96
<p>"Antitumor agent-96 (Compound D34) is a potent MRE11 inhibitor that down-regulates the homologous recombination (HR) pathway by binding to and suppressing the</p>Formula:C27H32N2O2Purezza:98%Colore e forma:SolidPeso molecolare:416.56Asparanin A
CAS:<p>Asparanin A, an apoptosis inducer with anticancer properties, arrests the cell cycle in the G0/G1 phase via the mitochondria and PI3K/AKT signaling pathways.</p>Formula:C39H64O13Purezza:98%Colore e forma:SolidPeso molecolare:740.92Anticancer agent 130
<p>Anticancer agent 130 (compound 8d) significantly induces apoptosis in A549 cells [1].</p>Formula:C38H46FN5O5Purezza:98%Colore e forma:SolidPeso molecolare:671.82,5-Dimethylcyclohexa-2,5-diene-1,4-dione
CAS:<p>2,5-Dimethylcyclohexa-2,5-diene-1,4-dione inhibits the viability of HL60 and K562 cells and exhibits antibacterial and anticancer properties.</p>Formula:C8H8O2Purezza:99.80%Colore e forma:SolidPeso molecolare:136.155-LOX-IN-2
CAS:<p>5-LOX-in-2: a 5-lipoxygenase inhibitor with IC50 of 0.33 μM, reduces kidney cancer cell activity, induces apoptosis.</p>Formula:C17H16O4Purezza:98.74%Colore e forma:SoildPeso molecolare:284.31Thalidomide-PEG2-C2-NH2 hydrochloride
CAS:<p>Thalidomide-based cereblon ligand with 2-unit PEG linker for PROTAC, in hydrochloride form.</p>Formula:C19H25ClN4O6Purezza:98%Colore e forma:SolidPeso molecolare:440.88JPS014 TFA
<p>JPS014 TFA, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), effectively degrades class I histone deacetylase (HDAC</p>Formula:C48H60F3N7O9SPurezza:98%Colore e forma:SolidPeso molecolare:968.092-aminobenzo[d]thiazol-6-ol
CAS:<p>2-aminobenzo[d]thiazol-6-ol: antimicrobial, antioxidant, anticancer; may trigger cancer cell apoptosis.</p>Formula:C7H6N2OSPurezza:98.27%Colore e forma:SolidPeso molecolare:166.2ZC0109
<p>ZC0109 inhibits IDO1 (50 nM) & TrxR1 (3.0 μM), induces ROS, arrests G1/S phase, causing cancer cell apoptosis.</p>Formula:C22H20BrFN8O4SColore e forma:SolidPeso molecolare:591.41N-Stearoyltyrosine
CAS:<p>N-Stearoyltyrosine (N-(1-Oxooctadecyl)-L-tyrosine) is an analog of Anandamide. It exhibits neuroprotective effects by safeguarding the CA1 region of the hippocampus in a gerbil ischemia-reperfusion model. Additionally, N-Stearoyltyrosine inhibits free radical generation, enhances antioxidant capacity, and reduces IR-induced apoptosis (cell apoptosis).</p>Formula:C27H45NO4Colore e forma:SolidPeso molecolare:447.65Conglobatin
CAS:<p>Conglobatin is a natural product for research related to life sciences. The catalog number is T36494 and the CAS number is 72263-05-9.</p>Formula:C28H38N2O6Colore e forma:SolidPeso molecolare:498.62WEHI-3773
<p>WEHI-3773 is an inhibitor of the interaction between VDAC2 and either BAK or BAX. It prevents BAX-mediated apoptosis (Apoptosis) by blocking the recruitment of BAX to the mitochondria through VDAC2. Conversely, WEHI-3773 promotes BAK-mediated apoptosis (Apoptosis) by limiting VDAC2's inhibitory sequestration of BAK. This compound shows promise for research in the field of cancer therapy.</p>Colore e forma:Odour SolidBCL-XL-IN-3
CAS:<p>BCL-XL-IN-3 (Compound 11) is an inhibitor of BCL-XL, with a Ki of less than 0.01 nM. It suppresses cell viability in both normal Molt-4 cells and digitonin-permeabilized Molt-4 cells, with EC50 values of 77.8 nM and 0.07 nM, respectively. BCL-XL-IN-3 can be utilized as an ADC toxin for synthesizing Clezutoclax.</p>Formula:C46H55N7O6SColore e forma:SolidPeso molecolare:834.04c-JUN peptide
CAS:<p>Peptide from c-Jun (33-57) blocks JNK binding, inhibits phosphorylation, upregulates p21, and induces HeLa cell apoptosis.</p>Formula:C121H210N36O34SPurezza:98%Colore e forma:SolidPeso molecolare:2743.55H3B-8800
CAS:<p>H3B-8800 is an SF3B1 modulator that can be used to study transfusion-dependent anemia.</p>Formula:C31H45N3O6Purezza:98.31%Colore e forma:SoildPeso molecolare:555.7184-B10
CAS:<p>84-B10 provides protection in cisplatin-induced acute kidney injury, reversing lipid peroxidation accumulation and downregulation of key ferroptosis inhibitors.</p>Formula:C25H22F3NO5Purezza:99.76%Colore e forma:SolidPeso molecolare:473.44EGFR/BRAFV600E-IN-3
<p>EGFR/BRAFV600E-IN-3 is an inhibitor targeting EGFR, BRAFV600E, and EGFRT790M with IC50 values of 57 nM, 68 nM, and 9.70 nM, respectively.</p>Formula:C25H18N4O3Purezza:98%Colore e forma:SolidPeso molecolare:422.44CDK9-Cyclin T1 PPI-IN-1
<p>CDK9-Cyclin T1 PPI-IN-1 (Compound B19) is a selective inhibitor of the CDK9-Cyclin T1 protein-protein interaction (PPI), suppressing cell proliferation in TNBC</p>Purezza:98%Colore e forma:Odour SolidHFY-4A
CAS:<p>HFY-4A is a novel HDAC inhibitor.HFY-4A has antitumour activity and has shown antiproliferative activity in breast cancer cells.</p>Formula:C20H19N3O2Purezza:98.66% - 99.22%Colore e forma:SoildPeso molecolare:333.38DiPT-4
<p>DiPT-4, a dual TOP1/PARP1 inhibitor, effectively induces DNA double-strand breaks (DSBs), cell cycle arrest, and apoptosis in cancer cells, with potential to</p>Formula:C32H22FN5O4SPurezza:98%Colore e forma:SolidPeso molecolare:591.61Pralnacasan
CAS:<p>Pralnacasan blocks IL-18, IL-1β, IFN-γ. It’s a potent oral enzyme inhibitor with use in arthritis therapy (Ki: 1.4 nM).</p>Formula:C26H29N5O7Purezza:98%Colore e forma:SolidPeso molecolare:523.54Borrelidin
CAS:<p>Borrelidin (Treponemycin) is an inhibitor of trehalose-6-phosphate synthase, a nitrogen-containing macrolide antibiotic isolated from Streptomyces rochei.</p>Formula:C28H43NO6Purezza:98%Colore e forma:White To Off-White PowderPeso molecolare:489.64NCT-58
CAS:<p>NCT-58 is a potent HSP90 inhibitor that blocks Akt, downregulates HER family, and induces apoptosis in HER2+ breast cancer without triggering HSR.</p>Formula:C27H34N2O5Purezza:99.55%Colore e forma:SolidPeso molecolare:466.57SACLAC
CAS:<p>SACLAC is a cysteine asparaginase activation inhibitor with antitumor activity used in the study of acute myeloid leukemia and cancer.</p>Formula:C20H40ClNO3Purezza:97.03%Colore e forma:SoildPeso molecolare:377.99Oxythiamine
CAS:<p>Oxythiamine (Hydroxythiamin) is a TK inhibitor that inhibits cancer cell proliferation, induces cell cycle arrest, and induces apoptosis.</p>Formula:C12H16N3O2SPurezza:96.14% - 99.51%Colore e forma:SolidPeso molecolare:266.34AS-99 TFA
<p>AS-99 TFA: potent ASH1L inhibitor, IC50=0.79 μM, combats leukemia, inhibits cell growth, induces apoptosis.</p>Colore e forma:SolidVEGFR-2-IN-36
<p>VEGFR-2-IN-36 (compound 15) serves as a potent VEGFR-2 inhibitor, exhibiting an IC50 value of 0.067 μM, and acts as an apoptosis inducer with demonstrated</p>Formula:C24H23N7O5Purezza:98%Colore e forma:SolidPeso molecolare:489.48SL-01
CAS:<p>SL-01, an oral gemcitabine derivative, potently induces apoptosis to hinder breast cancer more effectively than gemcitabine.</p>Formula:C18H18ClNO3Purezza:98%Colore e forma:White PowderPeso molecolare:331.79NS3694
CAS:<p>NS3694 is an inhibitor of apoptosis and inhibits apoptosome formation and caspase activation.</p>Formula:C15H10ClF3N2O3Purezza:99.83%Colore e forma:SolidPeso molecolare:358.7Mcl1-IN-12
CAS:<p>Mcl1-IN-12 has anti-tumor activity.It is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.29 and 3.1 μM, respectively.</p>Formula:C45H46N4O6S2Purezza:98%Colore e forma:SolidPeso molecolare:803Halenaquinone
CAS:<p>Halenaquinone: PI3K inhibitor, stops RAD51 DNA binding & osteoclastogenesis, induces PC12 cell apoptosis.</p>Formula:C20H12O5Purezza:98%Colore e forma:SolidPeso molecolare:332.31rac-CCT-250863 HCl
<p>rac-CCT-250863 HCl: NEK 2 inhibitor, halts cell cycle, anti-cancer growth, boosts Pomalidomide-induced apoptosis.</p>Formula:C24H26ClF3N4O2SPurezza:98.21%Colore e forma:SoildPeso molecolare:527MDM2-IN-21
CAS:<p>MDM2-IN-21 is a potent MDM2 inhibitor. MDM2-IN-21 can be used for the research of cancer.</p>Formula:C34H40Cl2N4O2Colore e forma:SolidPeso molecolare:607.62Cyclo(Arg-Gly-Asp-D-Phe-Val) TFA
CAS:<p>Arg-Gly-Asp-D-Phe-Val (TFA) has anti-tumor activity and is an inhibitor of integrin αvβ3.</p>Formula:C28H39F3N8O9Purezza:98%Colore e forma:SolidPeso molecolare:688.662Moflerafusp alfa
CAS:<p>Moflerafusp alfa is a fusion protein that targets the human signal-regulatory protein alpha (SIRPα) variant V2 D1 domain and human programmed death-ligand 1 (PD-L1). It shows potential for research in various cancer treatments.</p>Colore e forma:LiquidPROTAC TRIB2 degrader-1
<p>PROTAC TRIB2 degrader-1 (Compound 5k) is a potent TRIB2 degrader that selectively induces TRIB2 degradation via the CRBN-dependent ubiquitin-proteasome pathway. It effectively inhibits cell proliferation and induces cell apoptosis (apoptosis), making it useful in cancer research.</p>Formula:C45H45FN8O6Colore e forma:SolidPeso molecolare:812.89CRM1-IN-2
<p>CRM1-IN-2 (Compound KL2) is a noncovalent inhibitor that targets CRM1, localizing it to the nuclear periphery, depleting its nuclear presence, and inhibiting</p>Formula:C29H48N2O5Purezza:98%Colore e forma:SolidPeso molecolare:504.7MG-277
<p>MG-277 is a molecular glue compound transformed from PROTAC degradation agent, MG-277 potently inhibits tumor cell growth in a p53-independent manner.</p>Formula:C41H42Cl2FN5O5Purezza:98%Colore e forma:SolidPeso molecolare:774.71Bcl-xL antagonist 2
CAS:<p>Bcl-xL antagonist 2 is an effective and selective antagonist of Bcl-xL with an IC50 of 91 nM and a Ki of 65 nM.</p>Formula:C21H16N4O3S2Purezza:99.81%Colore e forma:SolidPeso molecolare:436.51CSF1R-IN-26
<p>CSF1R-IN-26 (Compound III-1) is an inhibitor of CSF-1R with an IC50 of 20.07 nM. It promotes the polarization of M2 macrophages to M1 macrophages, inducing apoptosis in MC-38 cancer cells. CSF1R-IN-26 inhibits the activation of the AKT/ERK/STAT3 signaling pathways, remodels the tumor immune microenvironment, and exhibits antitumor activity in mouse models. In SD rats, CSF1R-IN-26 demonstrates favorable pharmacokinetic properties, with a half-life of 1.86 hours and an oral bioavailability of 79.22%.</p>Colore e forma:Odour SolidEGFR-IN-153
<p>EGFR-IN-153 (Compound 5l) is an EGFR inhibitor that suppresses the proliferation of MDA-MB-231 cells with an IC50 of 0.73 μM and induces apoptosis. It is applicable for research in breast cancer.</p>Colore e forma:Odour Solid
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