Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(1 prodotti)
- Caspasi(154 prodotti)
- FOXO1(2 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(109 prodotti)
- PDK(9 prodotti)
- PERK(26 prodotti)
- Chinasi di serina/treonina(18 prodotti)
- Survivin(14 prodotti)
- TNF(64 prodotti)
- c-RET(61 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 6100 prodotti di "Apoptosi"
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Belinostat
CAS:Formula:C15H14N2O4SPurezza:>98.0%(HPLC)Colore e forma:White to Light yellow to Light orange powder to crystalPeso molecolare:318.35RITA
CAS:Formula:C14H12O3S2Purezza:>98.0%(GC)Colore e forma:White to Yellow to Orange powder to crystalPeso molecolare:292.37SEN177
CAS:SEN177 shows the potential in the research of Huntington's disease that is a potent inhibitor of glutaminyl cyclase (QPCT) with an IC 50 of 0.013μM for glutaminyl-peptide cyclotransferase-like (QPCTL). The Ki value of SEN177 for human glutaminyl cyclase (hQC) is 20 nM. SEN177 significantly reduces the early stages of mutant HTT oligomerisation and reduces the percentage of neurons with Q80 aggregates [1].Formula:C18H19FN6Colore e forma:SolidPeso molecolare:338.38KT-474
CAS:KT-474 (KYM-001) is a PROTAC degrader targeting IRAK4 with antitumor activity for the study of autoimmune diseases.Formula:C44H49F2N11O6Purezza:98.50% - 99.57%Colore e forma:SolidPeso molecolare:865.93NSC 80467
CAS:NSC 80467 inhibits survivin, targets DNA synthesis, induces γH2AX, and pKAP1 markers of DNA damage.Formula:C24H22BrN3O5Purezza:99.25%Colore e forma:SolidPeso molecolare:512.35KS100
CAS:KS100 inhibits ALDH1A1, ALDH2, ALDH3A1, boosts ROS, triggers apoptosis, and has anti-cancer properties.Formula:C17H14Br3N3O2SPurezza:97.05%Colore e forma:SolidPeso molecolare:564.09Amoscanate
CAS:Amoscanate is an antiparasitic agent. It is highly effective in animals against the four major species of schistosomes which infect humans.Formula:C13H9N3O2SColore e forma:SolidPeso molecolare:271.29Devazepide
CAS:Devazepide is a competitive, selective, orally available non-peptide CCK1 receptor antagonist that inhibits proliferation, induce apoptosis.Formula:C25H20N4O2Purezza:99.55%Colore e forma:SolidPeso molecolare:408.45Thioridazine
CAS:Thioridazine: an antipsychotic, anti-anxiety drug, blocks dopamine D2, PI3K-Akt-mTOR; halts angiogenesis, kills cancer cells, targets CSCs.Formula:C21H26N2S2Colore e forma:SolidPeso molecolare:370.57MCL-1/BCL-2-IN-2
CAS:MCL-1/BCL-2-IN-2 is a selective Mcl-1 and Bcl-2 inhibitor with potential antitumor activity for tumor research.Formula:C20H15BrN2O2SPurezza:98.03%Colore e forma:SolidPeso molecolare:427.31Triclabendazole (Standard)
CAS:Triclabendazole (Standard) is the standard substance of Triclabendazole, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Triclabendazole (CGA89317) has been used in trials studying Parasitic Disease.Formula:C14H9Cl3N2OSColore e forma:White To Brown Crystalline PowderPeso molecolare:359.66PBOX 6
CAS:PBOX 6 is a pyrrolo-1,5-benzoxazepine (PBOX) compound with anticancer and antitumor activity that inhibits the growth of breast cancer cells.Formula:C25H20N2O3Purezza:98.18% - 98.71%Colore e forma:SolidPeso molecolare:396.44Ref: TM-T16436
1mg59,00€5mg131,00€10mg187,00€25mg311,00€50mg462,00€100mg662,00€1mL*10mM (DMSO)140,00€Tegaserod
CAS:Tegaserod is a 5-HT4R agonist and 5-HT2B receptor antagonist with antitumor activity used in the treatment of irritable bowel syndrome (IBS).Formula:C16H23N5OPurezza:99.20% - 99.89%Colore e forma:SolidPeso molecolare:301.39SB 202190 hydrochloride
CAS:SB 202190 hydrochloride is a p38 MAPK inhibitor that inhibits p38α and p38β2 with selective, cell-permeable, and antitumor ,differentiation to cardiomyocytes.Formula:C20H15ClFN3OPurezza:99.99%Colore e forma:SolidPeso molecolare:367.8Ref: TM-T35592
2mg42,00€5mg62,00€10mg95,00€25mg138,00€50mg197,00€100mg293,00€200mg434,00€1mL*10mM (DMSO)67,00€Thalidomide D4
CAS:Thalidomide D4 is a deuterium labeled Thalidomide, has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties.Formula:C13H10N2O4Purezza:98%Colore e forma:SolidPeso molecolare:262.2513-Methyltetradecanoic acid
CAS:LeDSF3 controls HSAF production in Lysobacter, has antifungal properties, and acts as an anti-tumor by inhibiting p-AKT and activating caspase-3.Formula:C15H30O2Colore e forma:SolidPeso molecolare:242.43,4,5-Trihydroxycinnamic acid decyl ester
CAS:3,4,5-Trihydroxycinnamic acid decyl ester is an anti-obesity agent that inhibits lipid absorption and pancreatic lipase (EC50 ≈ 0.9μM).Formula:C19H28O5Purezza:98.28%Colore e forma:SolidPeso molecolare:336.42SC-560
CAS:Formula:C17H12ClF3N2OPurezza:>98.0%(HPLC)Colore e forma:White to Light yellow to Light orange powder to crystalPeso molecolare:352.74M47
CAS:M47 is a selective CRY1 (Cryptochrome 1) degradator that enhances nuclear degradation of CRY1, thereby extending the lifespan of p53 knockout mice.
Formula:C28H22ClNO4Colore e forma:SolidPeso molecolare:471.93Ref: TM-T74743
1mgPrezzo su richiesta5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaVenetoclax-d8
CAS:Venetoclax-d8 (ABT-199-d8) is a deuterated form of Venetoclax, a potent, selective, and orally active Bcl-2 inhibitor that induces autophagy and apoptosis.Formula:C45H42D8ClN7O7SColore e forma:SolidPeso molecolare:876.49Thalidomide-O-amido-PEG-C2-NH2
CAS:Thalidomide-based cereblon ligand linked to PEG-C2-NH2 for use in PROTAC E3 ligase conjugates.Formula:C19H22N4O7Colore e forma:SolidPeso molecolare:418.4NU 9056
CAS:NU 9056 is an effective and selective inhibitor of KAT5 histone acetyltransferase with an IC50 of 2 µM.Formula:C6H4N2S4Purezza:95.36% - 97.11%Colore e forma:SolidPeso molecolare:232.37Ref: TM-T23095
1mg80,00€2mgPrezzo su richiesta5mg156,00€10mg235,00€25mgPrezzo su richiesta1mL*10mM (DMSO)167,00€Mepazine hydrochloride
CAS:Mepazine hydrochloride (Pecazine hydrochloride) is a MALT1 inhibitor with anticancer and antitumor activity, inhibiting RANK-induced osteoclastogenesis.Formula:C19H23ClN2SPurezza:99.76%Colore e forma:SolidPeso molecolare:346.92Rottlerin
CAS:Formula:C30H28O8Purezza:>95.0%(HPLC)(qNMR)Colore e forma:Light yellow to Brown powder to crystalPeso molecolare:516.55Givinostat
CAS:Givinostat (ITF-2357) is a non-selective, orally active HDAC inhibitor capable of inhibiting STAT5 phosphorylation which is antitumour and anti-inflammatory .Formula:C24H27N3O4Purezza:98.56%Colore e forma:SolidPeso molecolare:421.5Everolimus-d4
CAS:Everolimus-d4 is a deuterated compound of Everolimus.Formula:C53H83NO14Colore e forma:SolidPeso molecolare:962.264Pevonedistat hydrochloride
CAS:Pevonedistat(MLN4924) hydrochloride is a NEDD8-activating enzyme inhibitor that induces apoptosis and can be used in the study of acute myeloid leukemias.Formula:C21H26ClN5O4SPurezza:98.44% - 99.19%Colore e forma:SolidPeso molecolare:479.98Galantamin-d6
CAS:Galantamin-d6 is a deuterated compound of Galantamin.Formula:C17H15D6NO3Colore e forma:SolidPeso molecolare:293.393-Acetylbenzophenone
CAS:3-Acetylbenzophenone is a bioactive chemical.Formula:C15H12O2Purezza:98%Colore e forma:SolidPeso molecolare:224.25L-Cystine, hydrochloride
CAS:L-Cystine, hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T124989 and the CAS number is 34760-60-6.Formula:C6H13ClN2O4S2Colore e forma:SolidPeso molecolare:276.75Melatonin-d4
CAS:Melatonin D5, a deuterium-labeled version of melatonin, is a hormone produced by the pineal gland, known for its role as a selective ATF-6 inhibitor that promotes apoptosis in human hepatoma cells via COX-2 downregulation. Additionally, it activates melatonin receptors and exhibits antioxidative and anti-inflammatory properties.Formula:C13H16N2O2Purezza:98%Colore e forma:SolidPeso molecolare:236.3PR-924
CAS:PR-924 is a selective inhibitor of tripeptide epoxyketone immunoproteasome subunit LMP-7 (IC50: 22 nM).Formula:C37H38N4O5Purezza:98%Colore e forma:SolidPeso molecolare:618.72Thalidomide-Piperazine 5-fluoride
CAS:Thalidomide-Piperazine 5-fluoride: a cereblon ligand-linked E3 ligase via PROTAC tech.Formula:C17H17FN4O4Colore e forma:SolidPeso molecolare:360.34Macitentan-d4
CAS:Macitentan-d4 (ACT-064992 D4) is a C13-labeled inhibitor of the peptides ETA and ETB used to study diseases mediated by endothelin receptor mediation.Formula:C19H20Br2N6O4SPurezza:96.51%Colore e forma:SolidPeso molecolare:592.3(R)-CR8 trihydrochloride
CAS:(R)-CR8 trihydrochloride (CR8, (R)-Isomer trihydrochloride) is a CDK1/2/5/7/9 inhibitor with neuroprotective activity that induces apoptosis.Formula:C24H32Cl3N7OPurezza:99.33%Colore e forma:SolidPeso molecolare:540.92Ref: TM-T12617
2mg39,00€5mg58,00€10mg88,00€25mg144,00€50mg210,00€100mg295,00€200mg440,00€1mL*10mM (DMSO)70,00€2'-Aminoacetophenone
CAS:Compound Fr14273 is a natural product for research related to life sciences. The catalog number is Fr14273 and the CAS number is 551-93-9.Formula:C8H9NOPurezza:99.88%Colore e forma:Pale Yellow Solid Solid CrystallinePeso molecolare:135.179-Nitrocamptothecin
CAS:Formula:C20H15N3O6Purezza:>98.0%(HPLC)Colore e forma:White to Yellow powder to crystalPeso molecolare:393.36PND-1186 hydrochloride
CAS:PND-1186 hydrochloride (VS-4718 hydrochloride) is a highly specific, reversible and potent inhibitor of FAK (IC50: 1.5 nM), which can selectively induceFormula:C25H27ClF3N5O3Colore e forma:SolidPeso molecolare:537.97Ezatiostat
CAS:Ezatiostat (TER199(free base)) is a tripeptide analog of glutathione that can selectively inhibit GSTP1-1 catalytic activity.Formula:C27H35N3O6SPurezza:97.95%Colore e forma:SolidPeso molecolare:529.65Ref: TM-T5097
2mg37,00€5mg54,00€10mg93,00€25mg157,00€50mg250,00€100mg432,00€200mg618,00€1mL*10mM (DMSO)79,00€BIX02188
CAS:BIX02188 is a selective and potent MEK5 inhibitor that inhibits MEK5-induced apoptosis in cells expressing the oncogenic mutant FLT3-ITD.Formula:C25H24N4O2Purezza:97.66%Colore e forma:SolidPeso molecolare:412.48trans-Pralsetinib
CAS:trans-Pralsetinib (trans-BLU-667) is an inhibitor of rearranged during transfection (RET).Formula:C27H32FN9O2Purezza:98%Colore e forma:SolidPeso molecolare:533.6Metronidazole-d4
CAS:Metronidazole-d4 is a deuterium labeled compound isotopic tracing.Metronidazole is an antibiotic and antiprotozoal oral and BBB penetration anaerobic bacteria.Formula:C6H9N3O3Colore e forma:SolidPeso molecolare:175.18Palmatine hydroxide
CAS:Palmatine hydroxide: oral IDO-1 inhibitor (IC50: 3-157μM), targets WNV protease, has anti-cancer/viral and neuroprotective properties.Formula:C21H23NO5Colore e forma:SolidPeso molecolare:369.41Isoquinoline
CAS:Compound PDK0035, with CAS No. 119-65-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0035 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C9H7NColore e forma:Liquid OthersolidPeso molecolare:129.15Pancratistatin
CAS:Pancratistatin, an isoquinoline from Hymenocallis littoralis, triggers apoptosis in melanoma and is studied for neuroblastoma, leukemia, and breast cancer.Formula:C14H15NO8Colore e forma:SolidPeso molecolare:325.27Sunitinib-d10
CAS:Sunitinib D10, a deuterium-enriched version, inhibits VEGFR2 and PDGFRβ tyrosine kinases (IC50: 80 nM/2 nM).Formula:C22H27FN4O2Purezza:98%Colore e forma:SolidPeso molecolare:408.54Amifostine thiol
CAS:Amifostine thiol (WR-1065), an active Amifostine metabolite, is a radioprotective cytoprotectant that activates p53 via JNK pathway.Formula:C5H14N2SPurezza:≥95.0%Colore e forma:SolidPeso molecolare:134.24Ancitabine
CAS:Ancitabine is an antitumour drug that improves Hailey-Hailey disease-related phenotypes in yeast models. inhibits DNA synthesis, acute leukaemia.Formula:C9H11N3O4Purezza:99.91%Colore e forma:SolidPeso molecolare:225.2C-DIM 12
CAS:Formula:C23H17ClN2Purezza:>98.0%(HPLC)(qNMR)Colore e forma:Orange to Amber to Dark red powder to crystalinePeso molecolare:356.85Chiisanoside
CAS:Chiisanoside is a useful organic compound for research related to life sciences. The catalog number is T123983 and the CAS number is 89354-01-8.Formula:C48H74O19Colore e forma:SolidPeso molecolare:955.101
