Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(11 prodotti)
- Caspasi(144 prodotti)
- FOXO1(3 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(139 prodotti)
- PDK(9 prodotti)
- PERK(26 prodotti)
- Chinasi di serina/treonina(18 prodotti)
- Survivin(14 prodotti)
- TNF(93 prodotti)
- c-RET(62 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 6070 prodotti di "Apoptosi"
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BTdCPU
CAS:BTdCPU is a potent activator of heme-regulated eIF2α kinase (HRI) . BTdCPU promotes eIF2α phosphorylation and induced apoptosis in resistant cell.Formula:C13H8Cl2N4OSPurezza:98.94% - 99.59%Colore e forma:SolidPeso molecolare:339.2Ref: TM-T7150
1mg145,00€5mg303,00€10mg465,00€25mg753,00€50mg1.074,00€100mg1.444,00€500mg2.822,00€1mL*10mM (DMSO)250,00€Angiotensin II human
CAS:<p>Angiotensin II acts on AT1/AT2 receptors, 30% similar seven-transmembrane glycoproteins, converted from Ang I by ACE.</p>Formula:C50H71N13O12Purezza:95% - >99.99%Colore e forma:SolidPeso molecolare:1046.18Olsalazine
CAS:Olsalazine (Dipentium), an anti-inflammatory drug, is used in the treatment of inflammatory bowel disease. It is also a novel DNA hypomethylating agent.Formula:C14H10N2O6Purezza:99.31%Colore e forma:SolidPeso molecolare:302.24SEC inhibitor KL-1
CAS:KL-1, a potent SEC inhibitor, disrupts the AFF4-CCNT1 interaction with a Ki of 3.48 μM, selectively targeting the SEC.Formula:C18H16ClNO4Purezza:97.42%Colore e forma:SolidPeso molecolare:345.78Ref: TM-T16867
1mg40,00€2mg55,00€5mg90,00€10mg131,00€25mg215,00€50mg325,00€100mg464,00€200mg645,00€1mL*10mM (DMSO)90,00€WYE-354
CAS:WYE-354 is a selective mTOR inhibitor (IC50=5 nM), targeting mTORC1/C2 over PI3Kα (>100x) and PI3Kγ (>500x), sparing P-AKT(T308).Formula:C24H29N7O5Purezza:97.86% - 99.61%Colore e forma:SolidPeso molecolare:495.53Simazine
CAS:<p>Simazine (Tafazine), a chlorotriazine herbicide/pesticide, may cause reproductive harm, endocrine disruption, and cancer.</p>Formula:C7H12ClN5Purezza:99.82%Colore e forma:SolidPeso molecolare:201.66TASIN-1
CAS:TASIN-1 is a small molecule inhibitor of mutant adenomatous polyposis coli (APC).Formula:C18H28N2O3SPurezza:99.86%Colore e forma:SolidPeso molecolare:352.49Ref: TM-T22632
1mg39,00€5mg84,00€10mg131,00€25mg269,00€50mg432,00€100mg638,00€500mg1.359,00€1mL*10mM (DMSO)92,00€NVP-ADW742
CAS:NVP-ADW742 (ADW) is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-AblFormula:C28H31N5OPurezza:96.14% - 98.70%Colore e forma:SolidPeso molecolare:453.58Isosorbide Mononitrate
CAS:Isosorbide Mononitrate (Corangin) is a Nitrate Vasodilator, dilating the blood vessels so as to reduce the blood pressure.Formula:C6H9NO6Purezza:98.16%Colore e forma:Isosorbide-5-Mononitrate Is A Crystalline Solid It Is Very Flammable And May Be Toxic By IngestionPeso molecolare:191.14TPCK
CAS:TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation, apoptosis, and tumorigenesisFormula:C17H18ClNO3SPurezza:97.33%Colore e forma:PowderPeso molecolare:351.85L524-0366
CAS:<p>L524-0366 ([1-(3-chlorophenyl)triazol-4-yl]-thiomorpholino-methanone) is a TWEAK-Fn14 signaling cascade inhibitor.</p>Formula:C13H13ClN4OSPurezza:98.6% - 99.13%Colore e forma:SolidPeso molecolare:308.79Tenilsetam
CAS:Tenilsetam: an endonuclease, nootropic, AGE inhibitor potential for Alzheimer's.Formula:C8H10N2OSPurezza:99.52%Colore e forma:SolidPeso molecolare:182.24Ref: TM-T8583
1mg62,00€5mg123,00€10mg180,00€25mg298,00€50mg419,00€100mg567,00€200mg752,00€1mL*10mM (DMSO)101,00€Benzarone
CAS:Benzarone (Benzarona) is a potent inhibitor of human uric acid transporter 1 (URAT1, IC50 = 2.8 μM in oocyte). Benzarone lowers the level of uric acid serum.Formula:C17H14O3Purezza:99.77%Colore e forma:SolidPeso molecolare:266.29Isobutylparaben
CAS:Isobutylparaben is a preservative and preservative insecticide.Formula:C11H14O3Purezza:99.36%Colore e forma:White CreamPeso molecolare:194.23Quinocetone
CAS:Quinocetone is an animal growth promoter and potential anti-tumor activity.Formula:C18H14N2O3Purezza:98.06%Colore e forma:SolidPeso molecolare:306.323,4 Dichloroisocoumarin
CAS:<p>3,4 Dichloroisocoumarin is a granzyme, cathepsin G, and neutrolphil elastase inhibitor</p>Formula:C9H4Cl2O2Purezza:97.94%Colore e forma:SolidPeso molecolare:215.03Thalidomide-NH-CH2-COOH TFA
CAS:2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}acetic acid (trifluoroacetic acid) is mainly used in compounds Synthesis.Formula:C17H14F3N3O8Purezza:95.00%Colore e forma:SolidPeso molecolare:445.3036Ref: TM-T50060
1mg37,00€5mg79,00€10mg105,00€25mg173,00€50mg259,00€100mg366,00€200mg500,00€1mL*10mM (DMSO)90,00€NS-3-008 hydrochloride
CAS:<p>NS-3-008 hydrochloride (NS-3-008 HCl) is a transcriptional G0/G1 switch 2 (G0s2) inhibitor( IC50 of 2.25 μM).</p>Formula:C14H24ClN3Purezza:99.56%Colore e forma:SolidPeso molecolare:269.81Z-VAD-FMK
CAS:Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases.Z-VAD-FMK binds to activated caspases and inhibits apoptosis.Z-VAD-FMK does notFormula:C21H28FN3O7Purezza:98.24% - 99.79%Colore e forma:SolidPeso molecolare:453.46Ref: TM-T7020
1mg118,00€5mg245,00€10mg416,00€25mg662,00€50mg939,00€100mg1.264,00€200mg1.691,00€1mL*10mM (DMSO)269,00€Licochalcone B
CAS:Licochalcone B inhibits human bladder cancer cells, reduces inflammation by NO, TNFalpha, and MCP-1, and a derivative protects against endotoxin shock.Formula:C16H14O5Purezza:99.33% - 99.9%Colore e forma:SolidPeso molecolare:286.28Ref: TM-T4S0350
1mg52,00€5mg117,00€10mg188,00€25mg329,00€50mg490,00€100mg710,00€1mL*10mM (DMSO)140,00€Rebastinib
CAS:<p>DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC,</p>Formula:C30H28FN7O3Purezza:99.53% - 99.79%Colore e forma:SolidPeso molecolare:553.59Pitstop 2
CAS:Pitstop2 is an amphipathic protein-bound inhibitor of the clathrin terminal domain. Pitstop2 has antitumor activity. Cost-effective, quality assurance.Formula:C20H13BrN2O3S2Purezza:99.54%Colore e forma:SolidPeso molecolare:473.36Ref: TM-T26357
1mg40,00€5mg88,00€10mg137,00€25mg274,00€50mg432,00€100mg638,00€200mg909,00€1mL*10mM (DMSO)96,00€Evofosfamide
CAS:Evofosfamide (TH-302) is a hypoxia-activated prodrug that releases Br-IPM in tumors to cause DNA damage and potentially induce apoptosis.Formula:C9H16Br2N5O4PPurezza:98.74% - 99.75%Colore e forma:SolidPeso molecolare:449.04Ref: TM-T3615
1mg52,00€5mg111,00€10mg154,00€25mg261,00€50mg419,00€100mg647,00€500mg1.349,00€1mL*10mM (DMSO)111,00€Amsilarotene
CAS:Amsilarotene (TAC101) blocks RB phosphorylation, boosts 2 CDK inhibitors, halts cell cycle, and reduces thymidylate synthase and cyclin A levels.Formula:C20H27NO3Si2Purezza:98.05%Colore e forma:SolidPeso molecolare:385.6Ref: TM-T21314
1mg43,00€2mg57,00€5mg96,00€10mg140,00€25mg273,00€50mg393,00€100mg560,00€200mg757,00€1mL*10mM (DMSO)96,00€Rigosertib sodium
CAS:Rigosertib sodium (ON-01910), a non-ATP-competitive inhibitor of PLK1(IC50=9 nM), exhibits 30-fold higher specificity activity over Plk2 and no effect on Plk3.Formula:C21H24NNaO8SPurezza:98% - 99.37%Colore e forma:SolidPeso molecolare:473.47IKK 16
CAS:IKK 16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.Formula:C28H29N5OSPurezza:98.76% - 99.61%Colore e forma:SolidPeso molecolare:483.63Ref: TM-T6176
1mg40,00€2mg52,00€5mg88,00€10mg139,00€25mg245,00€50mg406,00€100mg582,00€200mg825,00€1mL*10mM (DMSO)87,00€AZD1208
CAS:<p>AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.</p>Formula:C21H21N3O2SPurezza:97.24% - 99.83%Colore e forma:SolidPeso molecolare:379.48Propylparaben
CAS:Propylparaben (Propyl parahydroxybenzoate) is an antimicrobial agent, preservative, flavouring agentFormula:C10H12O3Purezza:99.84%Colore e forma:White Solid CrystallinePeso molecolare:180.20Tivantinib
CAS:Tivantinib (ARQ 197) is an orally bioavailable small molecule inhibitor of c-Met with potential antineoplastic activity.Formula:C23H19N3O2Purezza:98% - 99.41%Colore e forma:SolidPeso molecolare:369.42Maprotiline
CAS:Maprotiline blocks norepinephrine uptake, has antidepressant properties, and fights cancer by inducing apoptosis and inhibiting ERK and CRABP1.Formula:C20H23NColore e forma:SolidPeso molecolare:277.4Dapivirine HCl
CAS:Dapivirine HCl (TMC120) is a salt-based non-nucleoside HIV reverse transcriptase inhibitor with an IC50 of 24 nM, used in HIV-1 prevention.Formula:C20H20ClN5Colore e forma:SolidPeso molecolare:365.86YK-4-279
CAS:YK 4-279, an inhibitor of RNA Helicase A (RHA), binds to the oncogenic transciption factor EWS-FLI1.Formula:C17H13Cl2NO4Purezza:99.80% - ≥95%Colore e forma:SolidPeso molecolare:366.2EB-3D
CAS:EB-3D is a potent and selective choline kinase alpha 1 (ChoKα1) inhibitor(IC50 : 1 μM).with anti-cancer activity.Formula:C30H36Br2N4O2Purezza:99.48%Colore e forma:SolidPeso molecolare:644.4Ref: TM-T7955
1mg92,00€2mg120,00€5mg187,00€10mg274,00€25mg472,00€50mg655,00€100mg924,00€200mg1.225,00€1mL*10mM (DMSO)278,00€NVP-CGM097
CAS:NVP-CGM097 (CGM097) is an effective and specific MDM2 inhibitor (IC50: 1.7 nM for hMDM2).Formula:C38H47ClN4O4Purezza:98.77%Colore e forma:SolidPeso molecolare:659.26Ref: TM-TQ0231
1mg87,00€5mg207,00€10mg341,00€25mg520,00€50mg682,00€100mg944,00€1mL*10mM (DMSO)300,00€VTP50469 mesylate
CAS:VTP-50469: oral MeninMLL1 inhibitor for MLL/NPM1c+ leukemia; kills affected cell lines.Formula:C33H51FN6O7S2Colore e forma:SolidPeso molecolare:726.9244LDC000067
CAS:LDC000067 (LDC067) is a highly specific and selective CDK9 inhibitor with an IC50 value of 44±10 nM.Formula:C18H18N4O3SPurezza:98.08% - 99.07%Colore e forma:SolidPeso molecolare:370.43DC661
CAS:DC661 is a palmitoyl-protein thioesterase 1 (PPT1) inhibitor that acts as an anti-lysosomal agent by inhibiting autophagy, demonstrating anti-cancer activity.Formula:C31H39Cl2N5Purezza:99.07%Colore e forma:SolidPeso molecolare:552.58Ref: TM-T5538
1mg80,00€2mg105,00€5mg188,00€10mg319,00€25mg545,00€50mg780,00€100mg1.074,00€1mL*10mM (DMSO)230,00€K858 (Racemic)
CAS:K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.Formula:C13H15N3O2SPurezza:>99.99%Colore e forma:SolidPeso molecolare:277.34ELR510444
CAS:ELR510444 (LR510444) is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM.Formula:C19H16N2O2S2Purezza:97.67% - 98.69%Colore e forma:SolidPeso molecolare:368.47YH239-EE
CAS:YH239-EE, the ethyl ester of YH239, is a potent p53-MDM2 antagonist and an apoptosis inducer.Formula:C25H27Cl2N3O4Purezza:99.61%Colore e forma:SolidPeso molecolare:504.41Tolcapone
CAS:Tolcapone (Ro 40-7592) is a catechol-O-methyltransferase inhibitor used in the therapy of Parkinson disease as adjunctive therapy in combination with levodopaFormula:C14H11NO5Purezza:98.93% - 99.68%Colore e forma:SolidPeso molecolare:273.24Ref: TM-T6708
5mg38,00€10mg49,00€25mg87,00€50mg97,00€100mg131,00€200mg180,00€500mg300,00€1mL*10mM (DMSO)55,00€Didymin
CAS:Didymin, an antioxidant, may treat neuroblastoma and neurodegeneration by blocking N-Myc and boosting RKIP.Formula:C28H34O14Purezza:99.12% - 99.87%Colore e forma:Faintly Beige PowderPeso molecolare:594.56SCR7 pyrazine
CAS:SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).Formula:C18H12N4OSPurezza:98.72% - 99.85%Colore e forma:SolidPeso molecolare:332.38Ref: TM-T1724
1mg39,00€2mg50,00€5mg79,00€10mg120,00€25mg258,00€50mg408,00€100mg588,00€1mL*10mM (DMSO)79,00€3,6-Dihydroxyflavone
CAS:3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.Formula:C15H10O4Purezza:99.92%Colore e forma:SolidPeso molecolare:254.24Penicillic acid
CAS:<p>Penicillic acid, a mycotoxin from Aspergillus/Penicillium, blocks Fas ligand apoptosis and is cytotoxic to rat lung macrophages.</p>Formula:C8H10O4Purezza:98%Colore e forma:Needles From Petroleum Ether Slight Yellow PowderPeso molecolare:170.16Amifostine sodium
CAS:Amifostine sodium is a phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.Formula:C5H15N2NaO3PSColore e forma:SolidPeso molecolare:237.21C188-9
CAS:C188-9 (TTI-101) is a Stat3 inhibitor with an IC50 of 4-7 μM.Formula:C27H21NO5SPurezza:98.07% - >99.99%Colore e forma:SolidPeso molecolare:471.52Ref: TM-T4650
1g1.839,00€1mg46,00€2mg59,00€5mg87,00€10mg123,00€25mg250,00€50mg398,00€100mg593,00€500mg1.264,00€1mL*10mM (DMSO)96,00€XL888
CAS:XL888 is an orally bioavailable Hsp90 inhibitor, blocking cell proliferation and inducing tumor regression with an IC50 of 24 nM.Formula:C29H37N5O3Purezza:99.18%Colore e forma:SolidPeso molecolare:503.64Suberoyl bis-hydroxamic acid
CAS:SBHA is an HDAC inhibitor, an enzyme key to transcription, cell cycle, and development.Formula:C8H16N2O4Purezza:99.88%Colore e forma:SolidPeso molecolare:204.22
