Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(6 prodotti)
- BCL(11 prodotti)
- Caspasi(127 prodotti)
- FOXO1(3 prodotti)
- IAP(65 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(126 prodotti)
- PDK(9 prodotti)
- PERK(24 prodotti)
- Chinasi di serina/treonina(15 prodotti)
- Survivin(13 prodotti)
- TNF(91 prodotti)
- c-RET(51 prodotti)
- p53(62 prodotti)
Mostrare 6 più sottocategorie
Trovati 5622 prodotti di "Apoptosi"
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UC2288
CAS:<p>UC2288, a Sorafenib-based p21 attenuator, reduces p21 levels without affecting its stability.</p>Formula:C20H18ClF6N3O2Purezza:99.75%Colore e forma:SolidPeso molecolare:481.82GSK-J4
CAS:<p>GSK-J4 (GSK J4 HCl) is a cell permeable prodrug of GSK-J1, a dual inhibitor of the H3K27me3/me2 demethylases JMJD3/KDM6B and UTX/KDM6A. Cost effective and quality assured.</p>Formula:C24H27N5O2Purezza:98.24% - 99.98%Colore e forma:SolidPeso molecolare:417.5ZM 336372
CAS:<p>ZM 336372 is a potent and selective c-Raf inhibitor.</p>Formula:C23H23N3O3Purezza:97.24% - 97.51%Colore e forma:SolidPeso molecolare:389.45Cidofovir
CAS:Cidofovir ((S)-HPMPC) 通过特异性抑制病毒 DNA 合成来抑制病毒复制。Formula:C8H14N3O6PPurezza:99.24% - 99.76%Colore e forma:Fluffy White PowderPeso molecolare:279.19STM2457
CAS:<p>View and buy STM2457 from TargetMol.STM2457 is a first-in-class, highly potent, selective and orally active inhibitor of METTL3.Cited in 2 publications.</p>Formula:C25H28N6O2Purezza:97.44% - 98.90%Colore e forma:SolidPeso molecolare:444.53ML311
CAS:<p>ML311 is a selective inhibitor of the Mcl-1/Bim interaction.</p>Formula:C23H24F3N3OPurezza:99.75%Colore e forma:SolidPeso molecolare:415.45Rebastinib
CAS:<p>DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC,</p>Formula:C30H28FN7O3Purezza:99.53% - 99.79%Colore e forma:SolidPeso molecolare:553.59BAI1
CAS:<p>BAI1 (Bax channel blocker) is a potent inhibitor of Bax-mediated mitochondrial cytochrome C release (IC50: 0.52 μM).</p>Formula:C19H21Br2N3OPurezza:97.74%Colore e forma:SolidPeso molecolare:467.2BTdCPU
CAS:<p>BTdCPU is a potent activator of heme-regulated eIF2α kinase (HRI) . BTdCPU promotes eIF2α phosphorylation and induced apoptosis in resistant cell.</p>Formula:C13H8Cl2N4OSPurezza:98.94% - 99.59%Colore e forma:SolidPeso molecolare:339.2Lupeol
CAS:<p>Lupeol (Monogynol B) is a novel androgen receptor inhibitor with anti-inflammatory and antioxidant activity.</p>Formula:C30H50OPurezza:98% - 99.96%Colore e forma:Needles From Alcohol Acetone White PowderPeso molecolare:426.72Z-DEVD-FMK
CAS:<p>Z-DEVD-FMK (Caspase-3 Inhibitor) is a selective, irreversible Caspase-3 inhibitor, and also exhibits effective inhibition activity on caspase-6, caspase-7,</p>Formula:C30H41FN4O12Purezza:96.19% - 99.69%Colore e forma:SolidPeso molecolare:668.66Licochalcone B
CAS:<p>Licochalcone B inhibits human bladder cancer cells, reduces inflammation by NO, TNFalpha, and MCP-1, and a derivative protects against endotoxin shock.</p>Formula:C16H14O5Purezza:99.33% - 99.93%Colore e forma:SolidPeso molecolare:286.28Asiaticoside
CAS:<p>Asiaticoside, in Centella asiatica, may treat wounds/burns.</p>Formula:C48H78O19Purezza:98% - 99.96%Colore e forma:PowderPeso molecolare:959.12KRAS inhibitor-9
CAS:KRAS inhibitor-9 (DUN09716) hinders GTP-KRAS formation, with a Kd of 92 μM, causes G2/M arrest, and induces apoptosis in mutated NSC-LC cells.Formula:C13H9ClN2S2Purezza:99.66%Colore e forma:SolidPeso molecolare:292.81BML-210
CAS:<p>BML-210 (CAY10433) is a new-type HDAC inhibitor.</p>Formula:C20H25N3O2Purezza:96.37% - 98.12%Colore e forma:SolidPeso molecolare:339.43Nerol
CAS:<p>Nerol (Neryl alcohol) is a monoterpene found in many essential oils, such as lemon balm and hop.Nerol can lessened the severity of ouabain-triggered arrhythmias</p>Formula:C10H18OPurezza:98.59%Colore e forma:Colorless Oily Liquid LiquidPeso molecolare:154.25Indirubin
CAS:<p>Indirubin (Couroupitine B) is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 uM and 0.6 uM.</p>Formula:C16H10N2O2Purezza:97.21% - 99.74%Colore e forma:Reddish-Violet PowderPeso molecolare:262.26Pictilisib
CAS:<p>Pictilisib (GDC-0941) (GDC-0941) is a potent pan inhibitor of class I catalytic subunits of PI3K (IC50s: 3/33/3/75 nM for p110α/β/δ/γ).</p>Formula:C23H27N7O3S2Purezza:98.69% - 99.97%Colore e forma:SolidPeso molecolare:513.64ON1231320
CAS:<p>ON1231320 (GBO-006) is a Polo-like kinase 2 (PLK2) inhibitor.</p>Formula:C22H15F2N5O3SPurezza:97.31%Colore e forma:SolidPeso molecolare:467.45ICCB-19 hydrochloride
CAS:<p>ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the TRADD-N.</p>Formula:C12H22ClN3OSPurezza:99.3%Colore e forma:SolidPeso molecolare:291.84Ricolinostat
CAS:<p>Ricolinostat (Rocilinostat) is an orally bioavailable, specific inhibitor of histone deacetylase 6 (HDAC6) with potential antineoplastic activity.</p>Formula:C24H27N5O3Purezza:97.17% - 99.76%Colore e forma:SolidPeso molecolare:433.5Taurochenodeoxycholic acid sodium
CAS:<p>Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).</p>Formula:C26H44NNaO6SPurezza:98.23% - 99.45%Colore e forma:White To Off-White PowderPeso molecolare:521.68SR-4835
CAS:<p>SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13(CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM), which disables triple-negative breast cancer (</p>Formula:C21H20Cl2N10OPurezza:98.09% - >99.99%Colore e forma:SolidPeso molecolare:499.36PROCYANIDIN C1
CAS:<p>Procyanidin C1 is a natural polyphenol. It reduces Bcl-2 protein levels.Cost-effective and quality-assured.</p>Formula:C45H38O18Purezza:97.01% - 99.86%Colore e forma:SolidPeso molecolare:866.77AP-III-a4
CAS:AP-III-a4 (ENOblock) (ENOblock) is the first nonsubstrate analogue inhibitor of enolase with IC50 of 0.576 μM.Formula:C31H43FN8O3Purezza:98.24% - 99.90%Colore e forma:SolidPeso molecolare:594.72SB 415286
CAS:SB 415286 is a potent GSK3α inhibitor with IC50/Ki of 78 nM/31 nM with equally effective inhibition of GSK-3β.Formula:C16H10ClN3O5Purezza:99.55%Colore e forma:SolidPeso molecolare:359.72Thalidomide 4'-ether-alkylC2-amine hydrochloride
CAS:<p>Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) is a synthesized E3 ligase ligand-linker conjugate.</p>Formula:C15H16ClN3O5Purezza:98.56%Colore e forma:SolidPeso molecolare:353.76Sodium Demethylcantharidate
CAS:<p>Sodium Demethylcantharidate (Sodium norcantharidin) is extracted from Mylabris phqlarata pallas and has potent antitumor activity.</p>Formula:C8H9O5·NaPurezza:99.66% - ≥98%Colore e forma:SolidPeso molecolare:208.14SC66
CAS:<p>SC66 is a AKT inhibitor in HepG2, HA22T/VGH, and PLC/PRF/5 cells (IC50: about 0.75 μg/ml, at 72 h).</p>Formula:C18H16N2OPurezza:>99.99% - >99.99%Colore e forma:SolidPeso molecolare:276.33Euscaphic acid
CAS:<p>Euscaphic acid has anti-diabetic and anti-inflammatory effects, blocking IKK/MAPKs and NF-κB activation by disrupting TRAF6/IRAK1/TAK1 clustering.</p>Formula:C30H48O5Purezza:98.93%Colore e forma:SolidPeso molecolare:488.7Cichoric Acid
CAS:<p>Cichoric Acid (Dicaffeoyltartaric acid) is a potent inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues.</p>Formula:C22H18O12Purezza:97.87% - 98.77%Colore e forma:SolidPeso molecolare:474.37Neogambogic acid
CAS:<p>Neogambogic acid, an active ingredient in garcinia, can inhibit the growth of some solid tumors and result in an anticancer effect.</p>Formula:C38H46O9Purezza:97.74% - 99.38%Colore e forma:SolidPeso molecolare:646.77Importazole
CAS:<p>Importazole is an inhibitor of the nuclear transport receptor importin-β.</p>Formula:C20H22N4Purezza:99.6% - >99.99%Colore e forma:SolidPeso molecolare:318.42BAY 61-3606 HCl
CAS:<p>BAY 61-3606 HCl: a reversible Syk inhibitor, halts mast cell degranulation, cytokines, and sensitizes MCF-7 cells to TRAIL-induced apoptosis.</p>Formula:C20H19ClN6O3Colore e forma:SolidPeso molecolare:426.86FB23-2
CAS:<p>FB23-2 is a potent and selective mRNA N6-methyladenosine (m6A) demethylase FTO inhibitor(IC50 : 2.6 μM).</p>Formula:C18H15Cl2N3O3Purezza:97.29% - ≥95%Colore e forma:SolidPeso molecolare:392.24Rhapontin
CAS:<p>Rhapontin may reduce liver fat and better blood sugar/lipids, showing potential for treating type 2 diabetes.</p>Formula:C21H24O9Purezza:99% - 99.91%Colore e forma:Light YellowPeso molecolare:420.41Caudatin
CAS:Caudatin is one of the species of C-21 steroidal glycosides mainly isolated from the root of Cynanchum bungei Decne and exhibits potent anticancer activities.Formula:C28H42O7Purezza:98.83% - 99.84%Colore e forma:SolidPeso molecolare:490.63Thalidomide-O-amido-C6-NH2 TFA
CAS:Thalidomide-O-amido-C6-NH2 TFA (Cereblon Ligand-Linker Conjugates 11 TFA), a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-basedFormula:C46H53F6N8O16Purezza:95.16%Colore e forma:SolidPeso molecolare:1087.95ICCB280
CAS:<p>ICCB280 was capable of inducing differentiation and apoptosis of ATRA-resistant patient blasts strongly signify that the activity of this compound can overcome</p>Formula:C23H18N2O4Purezza:98.04%Colore e forma:SolidPeso molecolare:386.4Sophoraflavanone G
CAS:<p>Sophoraflavanone G (Kushenol F) (Kushenol F), isolated from Sophora flavescens, induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related</p>Formula:C25H28O6Purezza:97.09% - 99.77%Colore e forma:SolidPeso molecolare:424.49Tyrphostin AG1296
CAS:Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.Formula:C16H14N2O2Purezza:99.94% - >99.99%Colore e forma:SolidPeso molecolare:266.29Vandetanib trifluoroacetate
CAS:<p>Vandetanib trifluoroacetate: oral VEGFR2/KDR inhibitor, IC50=40nM, also blocks VEGFR3/FLT4 (110nM) and EGFR/HER1 (500nM).</p>Formula:C24H25BrF4N4O4Colore e forma:SolidPeso molecolare:589.386SC99
CAS:SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.Formula:C15H8Cl2FN3OPurezza:99.56%Colore e forma:SolidPeso molecolare:336.15Didanosine
CAS:<p>Didanosine (ddI) is a nucleoside reverse transcriptase inhibitor analog of adenosine (IC50: 0.49 μM).</p>Formula:C10H12N4O3Purezza:99.64%Colore e forma:White Crystalline PowderPeso molecolare:236.23Sulforaphene
CAS:<p>Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for velvetleaf at ~2x10^-4 M.</p>Formula:C6H9NOS2Purezza:97.55% - 99.19%Colore e forma:Slightly Yellowish LiquidPeso molecolare:175.27Prexasertib dihydrochloride
CAS:<p>Prexasertib dihydrochloride (LY2606368) inhibits CHK1 (Ki: 0.9 nM); IC50: CHK2 8 nM, RSK 9 nM.</p>Formula:C18H21Cl2N7O2Purezza:98.46% - 99.82%Colore e forma:SolidPeso molecolare:438.31Masitinib mesylate
CAS:<p>Masitinib mesylate (AB-1010 mesylate) is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;</p>Formula:C29H34N6O4S2Purezza:97.67% - 98.44%Colore e forma:SolidPeso molecolare:594.75PK11007
CAS:<p>PK11007 is an anti-p53 drug.</p>Formula:C15H11ClFN5O3S2Purezza:97.55%Colore e forma:SolidPeso molecolare:427.86PD184161
CAS:PD184161 is a novel, orally-active MEK inhibitor. PD184161 inhibited MEK activity (IC50 = 10-100 nM) in a time- and concentration-dependent manner[1].Formula:C17H13BrClF2IN2O2Purezza:99.40%Colore e forma:SolidPeso molecolare:557.56Phenoxyethanol
CAS:<p>Phenoxyethanol (NSC-1864) is germicidal. It often used together with quaternary ammonium compounds.</p>Formula:C8H10O2Purezza:99.47%Colore e forma:Clear To Practically Clear Colourless LiquidPeso molecolare:138.16
