Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(11 prodotti)
- Caspasi(141 prodotti)
- FOXO1(3 prodotti)
- IAP(66 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(138 prodotti)
- PDK(9 prodotti)
- PERK(25 prodotti)
- Chinasi di serina/treonina(14 prodotti)
- Survivin(14 prodotti)
- TNF(92 prodotti)
- c-RET(55 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 5865 prodotti di "Apoptosi"
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XL019
CAS:<p>XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold selectivity over JAK1.</p>Formula:C25H28N6O2Purezza:99.19%Colore e forma:SolidPeso molecolare:444.53Vandetanib
CAS:Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.Formula:C22H24BrFN4O2Purezza:99.7% - >99.99%Colore e forma:White SolidPeso molecolare:475.35Domatinostat
CAS:Domatinostat (4SC202) is a selective class I HDAC inhibitor. Domatinostat also displays inhibitory activity against Lysine specific demethylase 1 (LSD1).Formula:C23H21N5O3SPurezza:99.57% - 99.74%Colore e forma:SolidPeso molecolare:447.51CP-31398 dihydrochloride
CAS:<p>CP-31398 dihydrochloride is a p53 stabilizer which stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines.</p>Formula:C22H28Cl2N4OPurezza:98.23%Colore e forma:SolidPeso molecolare:435.4tubuloside B
CAS:<p>Tubuloside B from Cistanche salsa stems guards SH-SY5Y cells against TNFalpha-induced apoptosis.</p>Formula:C31H38O16Purezza:97.59% - 99.72%Colore e forma:SolidPeso molecolare:666.62Suberoyl bis-hydroxamic acid
CAS:SBHA is an HDAC inhibitor, an enzyme key to transcription, cell cycle, and development.Formula:C8H16N2O4Purezza:99.88%Colore e forma:SolidPeso molecolare:204.22ABT-737
CAS:<p>ABT-737 is a BH3 mimetic and an inhibitor of Bcl-2, Bcl-xL, and Bcl-w. ABT-737 exhibits antitumor activity and anti-aging activity. Cost-effective and quality-assured.</p>Formula:C42H45ClN6O5S2Purezza:98.15% - >99.99%Colore e forma:SolidPeso molecolare:813.43Prexasertib
CAS:Prexasertib (LY2606368) is a selective checkpoint kinase 1 (CHK1) inhibitor (Ki 0.9 nM, IC50<1 nM). antitumor activity. High-Quality, Low-Cost!Formula:C18H19N7O2Purezza:97.3% - 98.23%Colore e forma:SolidPeso molecolare:365.39PF-4989216
CAS:PF-4989216 is a potent and selective PI3K inhibitor with IC50 of 2 nM, 142 nM, 65 nM, 1 nM, and 110 nM for p110α, p110β, p110γ, p110δ, and VPS34, respectively.Formula:C18H13FN6OSPurezza:99.85%Colore e forma:SolidPeso molecolare:380.4C25-140
CAS:<p>C25-140 is a small-molecule inhibitor of TRAF6-Ubc13.</p>Formula:C26H31N7OPurezza:98.81%Colore e forma:SolidPeso molecolare:457.57Ziyuglycoside II
CAS:1.Formula:C35H56O8Purezza:99.52% - ≥95%Colore e forma:SolidPeso molecolare:604.81JX06
CAS:<p>JX06, a potent, selective and covalent PDK inhibitor, inhibits PDK1, PDK2 and PDK3 with IC50 of 49 nM, 101 nM and 313 nM respectively.</p>Formula:C10H16N2O2S4Purezza:99.4%Colore e forma:SolidPeso molecolare:324.51WT-161
CAS:WT161 is a potent and selective inhibitor of HDAC6 (IC50:0.40 nM).Formula:C27H30N4O3Purezza:95.98% - 98.34%Colore e forma:SolidPeso molecolare:458.55Diosgenin glucoside
CAS:<p>Diosgenin glucoside (Trillin) and other synthetic glycosides with similar activities may be of use in the management of hypercholesterolemia and atherosclerosis</p>Formula:C33H52O8Purezza:97.17% - 99.44%Colore e forma:SolidPeso molecolare:576.76MK-2206 dihydrochloride
CAS:<p>MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent and</p>Formula:C25H23Cl2N5OPurezza:99.228% - 99.94%Colore e forma:SolidPeso molecolare:480.394,5-Dicaffeoylquinic acid
CAS:1.Formula:C25H24O12Purezza:98.86% - ≥95%Colore e forma:SolidPeso molecolare:516.45Tauroursodeoxycholate dihydrate
CAS:Tauroursodeoxycholate (TUDCA ,Taurolite) dihydrate is a bile acid that reduces Caspase-3, Caspase-12, ERK, reducing endoplasmic reticulum stress mediated death.Formula:C26H49NO8SPurezza:99.82%Colore e forma:SolidPeso molecolare:535.73Geranyl acetate
CAS:Geranyl acetate is a monoterpene that has been found in C. sativa with diverse biological activities.Formula:C12H20O2Purezza:99.36%Colore e forma:Physical Description Clear Colorless Liquid With An Odor Of Lavender (Ntp 1992)Peso molecolare:196.29Tubastatin A
CAS:<p>Tubastatin A: Selective HDAC6 inhibitor, IC50 of 15 nM, 1000x less effective on other isozymes except HDAC8.</p>Formula:C20H21N3O2Purezza:97.22% - 99.51%Colore e forma:SolidPeso molecolare:335.4Deferitrin
CAS:<p>Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.</p>Formula:C11H11NO4SPurezza:98.71%Colore e forma:SolidPeso molecolare:253.27Tartrazine
CAS:Tartrazine, a food colorant with potential health risks, may be genotoxic and carcinogenic with long-term use.Formula:C16H9N4Na3O9S2Purezza:98.77% - 98.82%Colore e forma:Yellow Solid PowderPeso molecolare:534.36Isosilybin A
CAS:<p>Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (</p>Formula:C25H22O10Purezza:98.79%Colore e forma:SolidPeso molecolare:482.44Alisertib
CAS:Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib(MLN 8237) is >200-fold higher for Aurora A than Aurora B.Formula:C27H20ClFN4O4Purezza:98.31% - >99.99%Colore e forma:SolidPeso molecolare:518.92Pexidartinib
CAS:<p>Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential</p>Formula:C20H15ClF3N5Purezza:98.34% - 99.45%Colore e forma:SolidPeso molecolare:417.81Linalool
CAS:<p>Linalool, in essential oils, offers antinociceptive, antimicrobial, and anti-inflammatory effects, protects the liver, and boosts plant defense.</p>Formula:C10H18OPurezza:98.22%Colore e forma:Colorless Liquid Drypowder Liquid Othersolid LiquidPeso molecolare:154.25CIL56
CAS:<p>CIL56 (CA3) is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS).</p>Formula:C23H27N3O5S2Purezza:99.46% - 99.91%Colore e forma:SolidPeso molecolare:489.61TPEN
CAS:<p>TPEN (TPEDA) is a specific cell-permeable heavy metal chelator.</p>Formula:C26H28N6Purezza:98% - 99.72%Colore e forma:White Crystalline PowderPeso molecolare:424.54Milademetan free base
CAS:Milademetan (DS-3032b) is a potent MDM2 inhibitor, potentially blocking cancer growth by targeting p53 protein.Formula:C37H42Cl2FN5O7SPurezza:98%Colore e forma:SolidPeso molecolare:790.73Nutlin-3b
CAS:<p>Nutlin-3b, a less potent (+)-enantiomer of Nutlin-3, inhibits p53/MDM2 at IC50: 13.6 μM, 150x weaker than Nutlin-3a.</p>Formula:C30H30Cl2N4O4Purezza:98.83%Colore e forma:SolidPeso molecolare:581.49SRS16-86
CAS:<p>SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.</p>Formula:C26H32N4O2Purezza:97.73%Colore e forma:SolidPeso molecolare:432.56Rasagiline Mesylate
CAS:<p>Rasagiline Mesylate (AGN1135) is a novel MAO-B inhibitor, which can treat idiopathic Parkinson's disease.</p>Formula:C13H17NO3SPurezza:99.33%Colore e forma:White PowderPeso molecolare:267.342,5-dimethyl Celecoxib
CAS:2,5-dimethyl Celecoxib, a derivative targeting mPGES-1, inhibits PGE2 synthesis in inflammation.Formula:C18H16F3N3O2SPurezza:99.85%Colore e forma:SolidPeso molecolare:395.4AZD1208
CAS:<p>AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.</p>Formula:C21H21N3O2SPurezza:97.24% - 99.83%Colore e forma:SolidPeso molecolare:379.48Niraparib hydrochloride
CAS:<p>Niraparib hydrochloride (MK-4827) is a PARP inhibitor with potential cancer treatment effects, causing DNA damage and apoptosis.</p>Formula:C19H21ClN4OPurezza:99.26%Colore e forma:SolidPeso molecolare:356.85SHP099
CAS:SHP099 (SHP099 free base) free base is an effective, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 =0.07 μM and p-ERK modulation in cellsFormula:C16H19Cl2N5Purezza:98.73% - 99.4%Colore e forma:SolidPeso molecolare:352.26Propylparaben
CAS:Propylparaben (Propyl parahydroxybenzoate) is an antimicrobial agent, preservative, flavouring agentFormula:C10H12O3Purezza:99.84%Colore e forma:White Solid CrystallinePeso molecolare:180.20Navitoclax
CAS:<p>View and buy Navitoclax from TargetMol.Navitoclax (ABT-263) is a potent, orally bioavailable Bcl-2 family protein inhibitor that avidly binds Bcl-2.Cited in 4 publications.</p>Formula:C47H55ClF3N5O6S3Purezza:95.82% - >99.99%Colore e forma:Pale Yellow SolidPeso molecolare:974.61Diethylnorspermine HBr
CAS:DENSPM is a potent polyamine analog that induces SSAT, arrests the cell cycle, and triggers apoptosis in various cancer cells.Formula:C13H36Br4N4Colore e forma:SolidPeso molecolare:568.075AKN-028 trifluoroacetate
CAS:AKN-028 trifluoroacetate causes cell cycle arrest and lowers Myc genes and tyrosine kinase activity in AML.Formula:C19H15F3N6O2Colore e forma:SolidPeso molecolare:416.36SC-236
CAS:<p>SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).</p>Formula:C16H11ClF3N3O2SPurezza:99.74%Colore e forma:SolidPeso molecolare:401.79CASP3 Activator 1541
CAS:CASP3 Activator 1541 is an activator of the proenzyme forms of caspase-3, and induces cell death.Formula:C24H17N3O4Purezza:98.84%Colore e forma:SolidPeso molecolare:411.41Resatorvid
CAS:<p>Resatorvid (TAK-242) inhibits TLR4, with IC50s for IL-6, TNF-R, NO at 1.3, 1.9, 1.8 nM respectively.</p>Formula:C15H17ClFNO4SPurezza:99.31% - >99.99%Colore e forma:SolidPeso molecolare:361.82Briciclib
CAS:Briciclib (ON 014185) is a small molecule that suppresses cyclin D1 accumulation in Y cells.Formula:C19H23O10PSPurezza:98% - 99.84%Colore e forma:SolidPeso molecolare:474.42Quercetin
CAS:Quercetin (Sophoretin) is a natural flavonoid and is an agonist of SIRT1.Formula:C15H10O7Purezza:96.29% - 98.05%Colore e forma:Sensitive To Exposure To Air And Light Insoluble In Water Alcoholic Solutions Taste Very Bitter (Ntp 1992)Peso molecolare:302.24YK-4-279
CAS:<p>YK 4-279, an inhibitor of RNA Helicase A (RHA), binds to the oncogenic transciption factor EWS-FLI1.</p>Formula:C17H13Cl2NO4Purezza:99.80% - ≥95%Colore e forma:SolidPeso molecolare:366.2Selonsertib HCl
CAS:Selonsertib (GS-4997) is an oral ASK1 inhibitor with potential anti-inflammatory, antineoplastic, and anti-fibrotic effects.Formula:C24H25ClFN7OColore e forma:SolidPeso molecolare:481.96Piperazine Erastin
CAS:<p>Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.</p>Formula:C35H41ClN6O4Purezza:99.52%Colore e forma:SolidPeso molecolare:645.19WHI-P154
CAS:<p>WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.</p>Formula:C16H14BrN3O3Purezza:98% - 99.67%Colore e forma:SolidPeso molecolare:376.2S63845
CAS:<p>S63845 is a selective myeloid leukemia 1（MCL1) inhibitor that binds to human MCL1 with a Kd of 0.19 nM.Cost-effective and quality-assured.</p>Formula:C39H37ClF4N6O6SPurezza:97.7% - ≥98%Colore e forma:SolidPeso molecolare:829.26Mdivi-1
CAS:<p>Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM).</p>Formula:C15H10Cl2N2O2SPurezza:96.57% - 99.23%Colore e forma:SolidPeso molecolare:353.22
