Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(11 prodotti)
- Caspasi(141 prodotti)
- FOXO1(3 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(138 prodotti)
- PDK(9 prodotti)
- PERK(25 prodotti)
- Chinasi di serina/treonina(14 prodotti)
- Survivin(14 prodotti)
- TNF(89 prodotti)
- c-RET(56 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 5887 prodotti di "Apoptosi"
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Thalidomide 4'-ether-alkylC2-amine hydrochloride
CAS:<p>Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) is a synthesized E3 ligase ligand-linker conjugate.</p>Formula:C15H16ClN3O5Purezza:98.56%Colore e forma:SolidPeso molecolare:353.76Sodium Demethylcantharidate
CAS:<p>Sodium Demethylcantharidate (Sodium norcantharidin) is extracted from Mylabris phqlarata pallas and has potent antitumor activity.</p>Formula:C8H9O5·NaPurezza:99.66% - ≥98%Colore e forma:SolidPeso molecolare:208.14BAY 61-3606 HCl
CAS:BAY 61-3606 HCl: a reversible Syk inhibitor, halts mast cell degranulation, cytokines, and sensitizes MCF-7 cells to TRAIL-induced apoptosis.Formula:C20H19ClN6O3Colore e forma:SolidPeso molecolare:426.86FB23-2
CAS:<p>FB23-2 is a potent and selective mRNA N6-methyladenosine (m6A) demethylase FTO inhibitor(IC50 : 2.6 μM).</p>Formula:C18H15Cl2N3O3Purezza:97.29% - ≥95%Colore e forma:SolidPeso molecolare:392.24Thalidomide-O-amido-C6-NH2 TFA
CAS:Thalidomide-O-amido-C6-NH2 TFA (Cereblon Ligand-Linker Conjugates 11 TFA), a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-basedFormula:C46H53F6N8O16Purezza:95.16%Colore e forma:SolidPeso molecolare:1087.95ICCB280
CAS:<p>ICCB280 was capable of inducing differentiation and apoptosis of ATRA-resistant patient blasts strongly signify that the activity of this compound can overcome</p>Formula:C23H18N2O4Purezza:98.04%Colore e forma:SolidPeso molecolare:386.4Phenoxyethanol
CAS:<p>Phenoxyethanol (NSC-1864) is germicidal. It often used together with quaternary ammonium compounds.</p>Formula:C8H10O2Purezza:99.47%Colore e forma:Clear To Practically Clear Colourless LiquidPeso molecolare:138.16NSC-87877 disodium
CAS:NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2. NSC-87877 also inhibits EGF-induced Erk1/2 activation in HEK293 cells.Formula:C19H13N3O7S2·2NaPurezza:97.89%Colore e forma:SolidPeso molecolare:503.42Lenaldekar
CAS:<p>Lenaldekar (LDK) inhibits T-cell expansion and autoimmune encephalomyelitis.</p>Formula:C18H14N4Purezza:97.73%Colore e forma:SolidPeso molecolare:286.33Hederacolchiside A1
CAS:Hederacolchiside A1 exhibits anti-leishmanial and anticancer activities by disrupting cell membranes and inducing apoptosis via the PI3K/Akt/mTOR pathway.Formula:C47H76O16Purezza:98.76% - 99.92%Colore e forma:SolidPeso molecolare:897.1Bicyclol
CAS:<p>Bicyclol is an oral anti-hepatitis drug, decreasing ALT/AST levels by 50% and inhibiting HBV/HCV, boosting efficacy with interferon/lamivudine/adefovir.</p>Formula:C19H18O9Purezza:99.64% - 99.85%Colore e forma:SolidPeso molecolare:390.34Calcium dobesilate
CAS:Calcium dobesilate(CaD) has angioprotective properties and protects endothelial cells partly by ameliorating HG induced inflammation.Formula:C6H5O5SCa0Purezza:98.39%Colore e forma:White Or Almost PowderPeso molecolare:229.2ZYN57939
CAS:<p>ZYN57939 (MTR-106), an RNA polymerase I inhibitor, treats related diseases with a 0.855 μM IC50 against HT-29 cells.</p>Formula:C28H27N7O2SPurezza:99.81%Colore e forma:SolidPeso molecolare:525.62CBL0137 hydrochloride
CAS:<p>CBL0137 hydrochloride (Curaxin-137 hydrochloride) is an inhibitor of the histone chaperone FACT, which also activates p53 and inhibits NF-κB.Cost-effective and quality-assured.</p>Formula:C21H25ClN2O2Purezza:99.35% - 99.86%Colore e forma:SolidPeso molecolare:372.88Trametinib (DMSO solvate)
CAS:<p>Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) is a Highly Potent and Selective MEK Inhibitor that specifically inhibits MEK1/2(IC50 :2 nM)</p>Formula:C28H29FIN5O5SPurezza:98.82% - 99.92%Colore e forma:SolidPeso molecolare:693.53TCS PrP Inhibitor 13
CAS:TCS PrP Inhibitor 13 (5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One) is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation.Formula:C15H11N3O3Purezza:99.7%Colore e forma:SolidPeso molecolare:281.27Cladribine
CAS:Cladribine (2CdA), an adenosine deaminase inhibitor, is utilized in the treatment of lymphoproliferative diseases.Formula:C10H12ClN5O3Purezza:99.58% - >99.99%Colore e forma:White Crystalline SolidPeso molecolare:285.69Talampanel
CAS:Talampanel (LY-300164), an oral selective AMPA receptor antagonist, exhibits anti-seizure and neuroprotective properties.Formula:C19H19N3O3Purezza:98.3%Colore e forma:SolidPeso molecolare:337.37ENMD-1068 hydrochloride
CAS:<p>ENMD-1068 hydrochloride: selective PAR2 antagonist, counters liver fibrosis, hinders endometrial cell growth, and induces apoptosis in studies.</p>Formula:C15H30ClN3O2Colore e forma:SolidPeso molecolare:319.87Glycochenodeoxycholic acid sodium salt
CAS:GCDCA, a bile acid-glycine salt, is a secondary bile acid from colonic microbes.Formula:C26H42NNaO5Purezza:95.48% - 99.82%Colore e forma:SolidPeso molecolare:471.61Birinapant
CAS:<p>Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of</p>Formula:C42H56F2N8O6Purezza:97.08% - ≥95%Colore e forma:SolidPeso molecolare:806.94σ1 Receptor antagonist-1
CAS:σ1 Receptor antagonist-1 is a selective sigma 1 receptor antagonist.Formula:C21H23NOSPurezza:99.8%Colore e forma:SolidPeso molecolare:337.48IMM-01
CAS:<p>IMM-01 is a novel class of small-molecule agonists of the mammalian Diaphanous (mDia)-related formins, which act downstream of Rho GTPases to assemble actin</p>Formula:C12H17N3O2SPurezza:98.87%Colore e forma:SolidPeso molecolare:267.35Topotecan
CAS:<p>Topotecan (NSC-609669) is a Topoisomerase I inhibitor,and is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases.</p>Formula:C23H23N3O5Purezza:96.14% - 98.23%Colore e forma:Light Yellow Needle Crystal Or Crystalline PowderPeso molecolare:421.45DRB
CAS:<p>DRB is a nucleoside analog that inhibits several carboxyl-terminal domain (CTD) kinases including casein kinase II (IC50 range of 4-10 μM)</p>Formula:C12H12Cl2N2O4Purezza:99.46% - 99.83%Colore e forma:White To Off-White Crystalline SolidPeso molecolare:319.14Inauhzin
CAS:<p>Inauhzin (INZ) reactivates p53, inhibits SIRT1, induces Y cell apoptosis without genotoxic stress (IC50=3 uM in A549).</p>Formula:C25H19N5OS2Purezza:98% - 99.36%Colore e forma:SolidPeso molecolare:469.58Tenovin-6 Hydrochloride
CAS:Tenovin-6 HCl: Inhibits SIRT1 (21µM), SIRT2 (10µM), HDAC8; potent p53 activator.Formula:C25H35ClN4O2SPurezza:99.36%Colore e forma:SolidPeso molecolare:491.09S-(5'-Adenosyl)-L-methionine tosylate
CAS:<p>S-(5'-Adenosyl)-L-methionine tosylate (SAMe) is a ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNA</p>Formula:C22H30N6O8S2Purezza:80% - 98.18%Colore e forma:SolidPeso molecolare:570.64Azoramide
CAS:<p>Azoramide, a small-molecule modulator, has the antidiabetic activity of unfolded protein response.</p>Formula:C15H17ClN2OSPurezza:99.08% - 99.85%Colore e forma:SolidPeso molecolare:308.83Thalidomide-5-methyl
CAS:Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand. Thalidomide-5-methyl is used in the recruitment of CRBN protein.Formula:C14H12N2O4Purezza:99.48%Colore e forma:SolidPeso molecolare:272.26AZD3759 hydrochloride
CAS:<p>AZD3759 hydrochloride is an oral, CNS-penetrant EGFR inhibitor with IC50s of 0.2/0.3/0.2 nM.</p>Formula:C22H24Cl2FN5O3Purezza:99.62%Colore e forma:SolidPeso molecolare:496.36Ciprofloxacin hydrochloride monohydrate
CAS:<p>Ciprofloxacin hydrochloride monohydrate (Bay-09867 hydrochloride monohydrate) is a fluoroquinolone antibiotic with potent antibacterial activity.</p>Formula:C17H21ClFN3O4Purezza:99.23% - 99.85%Colore e forma:White Or Yellowish Crystalline PowderPeso molecolare:385.82Laquinimod
CAS:<p>Laquinimod (LAQ) is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral</p>Formula:C19H17ClN2O3Purezza:98.42% - 98.84%Colore e forma:SolidPeso molecolare:356.8Tenovin-3
CAS:Tenovin-3 acts as a p53 activator.Formula:C18H21N3OSPurezza:99.72% - ≥95%Colore e forma:SolidPeso molecolare:327.44Demethoxycurcumin
CAS:Demethoxycurcumin: antioxidant, anti-inflammatory, anti-proliferative, anti-acanthamoebic, enhances chemo for resistant cancers, inhibits cancer pathways.Formula:C20H18O5Purezza:94.54% - 99.86%Colore e forma:SolidPeso molecolare:338.35A-419259
CAS:A-419259 (RK-20449) is an apoptosis inducer that selectively inhibits the Src family of kinases, including Src,LCK, and Lyn, with an IC50=3 to 9 nM.Formula:C29H34N6OPurezza:99.48%Colore e forma:SolidPeso molecolare:482.62Ro-3306
CAS:<p>RO-3306: ATP-competitive CDK1 inhibitor, Ki 20 nM, >15x more selective than other human kinases.</p>Formula:C18H13N3OS2Purezza:97.67% - 99.79%Colore e forma:SolidPeso molecolare:351.45PKD-IN-1 dihydrochloride (956121-30-5 free base)
CAS:<p>CRT0066101 dihydrochloride is an inhibitor of PKD.</p>Formula:C18H21Cl3N4OPurezza:99.5%Colore e forma:SolidPeso molecolare:415.75Tauroursodeoxycholate
CAS:Tauroursodeoxycholate (UR 906), a hydrophilic bile acid, low in humans, may treat PBC, insulin resistance, and ALS.Formula:C26H45NO6SPurezza:98.77% - 99.93%Colore e forma:White SolidPeso molecolare:499.7PEAQX
CAS:<p>PEAQX (NVP-AAM077) is an oral NMDA antagonist, inhibits 1A/2A receptors (IC50: 270 nM), less so 1A/2B (IC50: 29,600 nM).</p>Formula:C17H17BrN3O5PPurezza:98% - 99.9%Colore e forma:SolidPeso molecolare:454.21AR42
CAS:<p>AR42 (OSU-HDAC42) is an HDAC inhibitor (IC50: 30 nM).</p>Formula:C18H20N2O3Purezza:98.46% - 98.96%Colore e forma:SolidPeso molecolare:312.36Emricasan
CAS:<p>Emricasan (IDN-6556) is a pan-caspase inhibitor with irreversible properties.</p>Formula:C26H27F4N3O7Purezza:98.13% - 99%Colore e forma:SolidPeso molecolare:569.5Aloperine
CAS:<p>Aloperine exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.</p>Formula:C15H24N2Purezza:98% - 99.88%Colore e forma:Yellow Crystalline PowderPeso molecolare:232.361400W dihydrochloride
CAS:1400W dihydrochloride (N-(3-(Aminomethyl)benzyl)acetamidine) is a highly effective and specific inhibitor of inducible NOS2 (iNOS).Formula:C10H17Cl2N3Purezza:98% - 99.94%Colore e forma:SolidPeso molecolare:250.17Bilobalide
CAS:<p>Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations.</p>Formula:C15H18O8Purezza:98.81% - 99.92%Colore e forma:White SolidPeso molecolare:326.3Ipatasertib
CAS:<p>Ipatasertib (GDC-0068) is a selective, ATP-competitive pan-Akt inhibitor that can lead to p53-independent PUMA activation.Cost-effective and quality-assured.</p>Formula:C24H32ClN5O2Purezza:98.28% - 99.21%Colore e forma:SolidPeso molecolare:458Sulforaphane
CAS:Sulforaphane is a natural isothiocyanate that activates Nrf2. Sulforaphane has antitumor and anti-inflammatory activities. Cost-effective and quality-assured.Formula:C6H11NOS2Purezza:95% - 99.79%Colore e forma:Light Yellow LiquidPeso molecolare:177.29Nω-Hydroxy-nor-L-Arginine Dihydrochloride
CAS:<p>Nω-Hydroxy-nor-L-Arginine Dihydrochloride is a competitive and reversible inhibitor of arginase</p>Formula:C5H14Cl2N4O3Purezza:99.12% - 99.84%Colore e forma:SolidPeso molecolare:249.10ZZW-115 hydrochloride
CAS:ZZW-115 hydrochloride inhibits the activity of NUPR1.Formula:C24H34Cl3F3N4SPurezza:99.97%Colore e forma:SolidPeso molecolare:573.97Chromium picolinate
CAS:<p>Chromium picolinate causes DNA damage and mutation. It is an activator of p38.</p>Formula:C18H12CrN3O6Purezza:99.64%Colore e forma:Violet-Red Crystalline PowderPeso molecolare:418.30
