Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(1 prodotti)
- Caspasi(154 prodotti)
- FOXO1(2 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(127 prodotti)
- PDK(9 prodotti)
- PERK(23 prodotti)
- Chinasi di serina/treonina(17 prodotti)
- Survivin(14 prodotti)
- TNF(90 prodotti)
- c-RET(61 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 6170 prodotti di "Apoptosi"
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GSK4112
CAS:GSK4112 (SR6452) is a Rev-erbα agonist with EC50 of 0.4 μM, also is a small molecule chemical probe for the cell biology of the nuclear heme receptor Rev-erbα.Formula:C18H21ClN2O4SPurezza:99.69%Colore e forma:SolidPeso molecolare:396.89Triglycidyl isocyanurate
CAS:Triglycidyl isocyanurate (Teroxirone) is a cancer-research chemical with DNA-altering properties, also used in metal finishing.Formula:C12H15N3O6Purezza:99.01%Colore e forma:White Solid ParticulatesPeso molecolare:297.26Isolongifolene
CAS:Isolongifolene ((-)-Isolongifolene), a tricyclic sesquiterpene isolated from Murraya koenigii, exhibits antioxidant, anti-inflammatory, anticancer, andFormula:C15H24Purezza:90.13% - 99.46%Colore e forma:Colorless Or Light Yellow LiquidPeso molecolare:204.35Cichoric Acid
CAS:Cichoric Acid (Dicaffeoyltartaric acid) is a potent inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues.Formula:C22H18O12Purezza:97.87% - 98.77%Colore e forma:SolidPeso molecolare:474.37ELR510444
CAS:ELR510444 (LR510444) is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM.Formula:C19H16N2O2S2Purezza:97.67% - 98.69%Colore e forma:SolidPeso molecolare:368.47Benidipine hydrochloride
CAS:Benidipine hydrochloride (Coniel) , a hydrochloride salt form of benidipine, is used as a blocker of dihydropyridine calcium channel.Formula:C28H32ClN3O6Purezza:99.80%Colore e forma:SolidPeso molecolare:542.03Caudatin
CAS:Caudatin is one of the species of C-21 steroidal glycosides mainly isolated from the root of Cynanchum bungei Decne and exhibits potent anticancer activities.Formula:C28H42O7Purezza:98.83% - 99.84%Colore e forma:SolidPeso molecolare:490.63Ref: TM-T3150
1mg52,00€5mg100,00€1mL*10mM (DMSO)119,00€10mg166,00€25mg279,00€50mg398,00€100mg532,00€200mg705,00€Apilimod 2HCl
CAS:Apilimod 2HCl (STA 5326 2HCl) is a PIKFYVE kinase inhibitor used in the study of amyotrophic lateral sclerosis.Formula:C23H28Cl2N6O2Purezza:98.41%Colore e forma:SolidPeso molecolare:491.41Abacavir monosulfate
CAS:Abacavir monosulfate: oral HIV inhibitor, anticancer; crosses blood-brain barrier, suppresses telomerase.Formula:C14H20N6O5SColore e forma:SolidPeso molecolare:384.41CM-272
CAS:CM-272 is a dual G9a/DNA methyltransferases (DNMTs) inhibitor.Formula:C28H38N4O3Purezza:97.83%Colore e forma:SolidPeso molecolare:478.63PK11000
CAS:PK11000 is a p53 targeting compound, has anti-tumor activities through activation of unstable p53.Formula:C6H5ClN2O4SPurezza:99.70%Colore e forma:SolidPeso molecolare:236.63Taurodeoxycholic acid sodium hydrate
CAS:Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat.Formula:C26H46NNaO7SPurezza:99.95%Colore e forma:SolidPeso molecolare:539.70Z-YVAD-FMK
CAS:AA-Z-YVAD-FMK is a Irreversible caspase-1 inhibitor,with anti-inflammatory and anti-tumor activities.Formula:C31H39FN4O9Purezza:98.00%Colore e forma:SolidPeso molecolare:630.66SC99
CAS:SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.Formula:C15H8Cl2FN3OPurezza:99.56%Colore e forma:SolidPeso molecolare:336.15Ref: TM-T8719
1mg43,00€5mg87,00€1mL*10mM (DMSO)94,00€10mg133,00€25mg227,00€50mg344,00€100mg429,00€200mg597,00€MG-132
CAS:MG-132 (Z-Leu-Leu-Leu-al) is a 26S proteasome inhibitor, cell-permeable and reversible,an autophagy activator, induces apoptosis. High-Quality, Low-Cost!Formula:C26H41N3O5Purezza:95% - 99.99%Colore e forma:White To Off-White PowderPeso molecolare:475.62Ref: TM-T2154
1mL*10mM (DMSO)44,00€10mg46,00€25mg84,00€50mg137,00€100mg205,00€200mg356,00€500mg447,00€Clodronate disodium tetrahydrate
CAS:Clodronate disodium tetrahydrate (Clastoban) inhibits bone resorption and soft tissue calcification.Formula:CH10Cl2Na2O10P2Purezza:98%Colore e forma:SolidPeso molecolare:360.92Benzydamine
CAS:Benzydamine: analgesic, antipyretic, anti-inflammatory; reduces pain, swelling, aids healing post-surgery/trauma.Formula:C19H23N3OPurezza:97.872% - 98.34%Colore e forma:SolidPeso molecolare:309.41Rimiducid
CAS:Rimiducid, a tacrolimus analogue, dimerizes FKBP domains to activate Caspase 9 and induce apoptosis; binds FKBP12 weakly.Formula:C78H98N4O20Purezza:99.54%Colore e forma:SolidPeso molecolare:1411.63Ref: TM-T14298
1mg129,00€2mg177,00€5mg285,00€10mg420,00€25mg692,00€50mg973,00€100mg1.305,00€500mg2.602,00€GW 5074
CAS:GW 5074 (Raf1 Kinase Inhibitor I)(IC50=9 nM) is an effective and specific c-Raf inhibitor.Formula:C15H8Br2INO2Purezza:99.32%Colore e forma:SolidPeso molecolare:520.94Sulfaphenazole
CAS:Sulfaphenazole (Plisulfan) is an inhibitor of CYP2C9 (Ki: 0.3 μM) that demonstrates at least 100-fold selectivity over other CYP450 isoforms (Ki: 63/29 μM for
Formula:C15H14N4O2SPurezza:97.53% - 99.67%Colore e forma:SolidPeso molecolare:314.36Verteporfin
CAS:Verteporfin (BPD-MA) is a YAP inhibitor that inhibits YAP-TEAD interactions.Formula:C41H42N4O8Purezza:95.37% - 99.82%Colore e forma:Dark Green To Black SolidPeso molecolare:718.79Ref: TM-T3112
1mg38,00€2mg49,00€5mg80,00€10mg109,00€1mL*10mM (DMSO)114,00€25mg213,00€50mg346,00€100mg437,00€Britannin
CAS:Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.Formula:C19H26O7Purezza:98% - 99.98%Colore e forma:SolidPeso molecolare:366.41LCL161
CAS:LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP and cIAP1. LCL161 has potential antitumor activity. Cost-effective and quality-assured.Formula:C26H33FN4O3SPurezza:99.13% - 99.87%Colore e forma:SolidPeso molecolare:500.63Thalidomide-NH-C6-NH2 hydrochloride
CAS:Pomalidomide-C6-NH2 HCl is a synthetic conjugate for PROTAC, combining CRBN ligand and linker.Formula:C19H25ClN4O4Purezza:99.27%Colore e forma:SolidPeso molecolare:408.88Sodium Oxamate
CAS:Sodium Oxamate (Oxamic acid sodium salt) is an LDH inhibitor that specifically inhibits LDHA.Formula:C2H2NNaO3Purezza:99.23% - ≥98%Colore e forma:White Crystalline PowderPeso molecolare:111.03Alisertib
CAS:Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib(MLN 8237) is >200-fold higher for Aurora A than Aurora B.Formula:C27H20ClFN4O4Purezza:98.31% - >99.99%Colore e forma:SolidPeso molecolare:518.92Ref: TM-T2241
5mg52,00€1mL*10mM (DMSO)59,00€10mg92,00€25mg146,00€50mg215,00€100mg334,00€200mg430,00€500mg705,00€Thalidomide-propargyl
CAS:Thalidomide-propargyl, a Cereblon ligand, links proteins in PROTAC formation.Formula:C16H12N2O5Purezza:95.14%Colore e forma:SolidPeso molecolare:312.28Ketorolac hemicalcium
CAS:Ketorolac hemicalcium: NSAID, COX-1/COX-2 inhibitor (IC50: 20/120 nM), treats eye inflammation & pain, used in cancer research.Formula:C30H24CaN2O6Colore e forma:SolidPeso molecolare:548.608Thapsigargin
CAS:Thapsigargin is a natural product, an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) and an endoplasmic reticulum stress inducer.Formula:C34H50O12Purezza:99.07% - 99.3%Colore e forma:Colourless FilmPeso molecolare:650.75Psoralen
CAS:Psoralen (Ficusin) is a furocoumarin that intercalates with DNA, inhibiting DNA synthesis and cell division.
Formula:C11H6O3Purezza:99.3% - 99.87%Colore e forma:Crystals From Ether Crystalline SolidPeso molecolare:186.16Perhexiline
CAS:Perhexiline: oral CPT1/2 inhibitor, limits fat metabolism, crosses BBB, anti-cancer, induces liver cell apoptosis, for cancer/cardio research.Formula:C19H35NColore e forma:SolidPeso molecolare:277.49KRCA-0008
CAS:KRCA-0008 is an effective and specific ALK/Ack1 inhibitor (IC50: 12/4 nM); displays drug-like properties without hERG liability.Formula:C30H37ClN8O4Purezza:96.19%Colore e forma:SolidPeso molecolare:609.12Carnosic acid
CAS:Carnosic acid is a lipid absorption inhibitor, endowed with antioxidative, antimicrobial, photoprotective potential, and antiproliferative properties.Formula:C20H28O4Purezza:98.31% - 99.5%Colore e forma:Yellow PowderPeso molecolare:332.43Tubeimoside I
CAS:Tubeimoside I (Tubeimoside-1)(Lobatoside-H) is an extract from Chinese herbal medicine Bolbostemma paniculatum (MAXIM).Formula:C63H98O29Purezza:98.89% - 99.94%Colore e forma:SolidPeso molecolare:1319.43Ref: TM-T2715
5mg34,00€10mg42,00€1mL*10mM (DMSO)52,00€25mg58,00€50mg81,00€100mg105,00€200mg152,00€500mg245,00€K858 (Racemic)
CAS:K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.Formula:C13H15N3O2SPurezza:>99.99%Colore e forma:SolidPeso molecolare:277.34Bigelovin
CAS:Bigelovin: RXRα agonist, inhibits mTOR via ROS, induces apoptosis/autophagy, anti-tumor sesquiterpene from Inula sp.Formula:C17H20O5Purezza:99.61% - 99.72%Colore e forma:SolidPeso molecolare:304.34Ref: TM-TN6735
1mg96,00€1mL*10mM (DMSO)203,00€5mg205,00€10mg268,00€25mg465,00€50mg662,00€100mg888,00€Thalidomide-O-amido-PEG3-C2-NH2 TFA
CAS:Synthetic E3 ligase ligand-linker, Thalidomide-O-amido-PEG3-C2-NH2 TFA, used in PROTAC with cereblon ligand and PEG.Formula:C25H31F3N4O11Purezza:99.82%Colore e forma:SolidPeso molecolare:620.54OICR-9429
CAS:OICR-9429 blocks WDR5 binding to MLL/Histone 3, hindering acute myeloid leukemia cell growth in vitro.Formula:C29H32F3N5O3Purezza:97.07% - 99.93%Colore e forma:SolidPeso molecolare:555.59Ref: TM-T6916
1mg34,00€2mg49,00€5mg71,00€1mL*10mM (DMSO)92,00€10mg105,00€25mg177,00€50mg295,00€100mg475,00€Quizartinib
CAS:Quizartinib (AC220) is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases.Formula:C29H32N6O4SPurezza:98% - 99.42%Colore e forma:SolidPeso molecolare:560.67Ref: TM-T2066
5mg58,00€1mL*10mM (DMSO)71,00€10mg79,00€25mg97,00€50mg127,00€100mg202,00€200mg300,00€500mg507,00€Pinosylvin
CAS:Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.Formula:C14H12O2Purezza:99.89% - 99.91%Colore e forma:SolidPeso molecolare:212.24Juglanin
CAS:Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis and autophagy on human breast cancer cells.Formula:C20H18O10Purezza:98.8% - 99.33%Colore e forma:SolidPeso molecolare:418.35Levistolide A
CAS:1. Levistolide A (Diligustilide) inhibits liver fibrosis and angiogenesis.Formula:C24H28O4Purezza:98.93% - 99.22%Colore e forma:SolidPeso molecolare:380.48Ref: TM-T6S1292
1mg34,00€5mg65,00€1mL*10mM (DMSO)73,00€10mg94,00€25mg137,00€50mg193,00€100mg286,00€200mg423,00€GSK547
CAS:GSK547 (GSK'547) is a highly selective and potent inhibitor of RIP1 kinase,inhibits macrophage-mediated adaptive immune tolerance in pancreatic cancer.Formula:C20H18F2N6OPurezza:99.17%Colore e forma:SolidPeso molecolare:396.39Cabozantinib S-malate
CAS:Cabozantinib S-malate (XL184) is the salt form of cabozantinib, an orally bioavailable, small molecule RTK inhibitor with potential antineoplastic activity.Formula:C32H30FN3O10Purezza:98% - >99.99%Colore e forma:SolidPeso molecolare:635.59BRD3308
CAS:BRD3308 is a highly selective inhibitor of HDAC3(IC50 of 54 nM), attenuating PE-mediated phosphorylation of ERK but not JNK.Formula:C15H14FN3O2Purezza:97%Colore e forma:SolidPeso molecolare:287.29Ref: TM-T8233
2mg42,00€5mg62,00€1mL*10mM (DMSO)66,00€10mg92,00€25mg178,00€50mg295,00€100mg462,00€200mg655,00€Olanzapine HCl
CAS:Olanzapine HCl, an FDA-approved atypical antipsychotic for schizophrenia and bipolar disorder, resembles clozapine and quetiapine.Formula:C17H21ClN4SColore e forma:SolidPeso molecolare:348.89Tomivosertib
CAS:Tomivosertib (eFT508) is a potent, highly selective MNK1 and MNK2 inhibitor with IC50 value of 1-2 nM.Formula:C17H20N6O2Purezza:97.34% - 99.72%Colore e forma:SolidPeso molecolare:340.382-tert-Butyl-1,4-benzoquinone
CAS:TBQ, a BHA metabolite, activates Nrf2 and S-arylates Keap1 in RAW264.7 cells.Formula:C10H12O2Purezza:97.19%Colore e forma:SolidPeso molecolare:164.2SKF-86002
CAS:SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).Formula:C16H12FN3SPurezza:98% - 99.85%Colore e forma:SolidPeso molecolare:297.351,4-Naphthoquinone
CAS:1,4-Naphthoquinone used as inhibitor for monoamine oxidase, DNA topoisomerase, and acetyltransferase.Formula:C10H6O2Purezza:99.24% - 99.56%Colore e forma:SolidPeso molecolare:158.15
