Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(1 prodotti)
- Caspasi(154 prodotti)
- FOXO1(2 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(134 prodotti)
- PDK(9 prodotti)
- PERK(23 prodotti)
- Chinasi di serina/treonina(17 prodotti)
- Survivin(14 prodotti)
- TNF(93 prodotti)
- c-RET(61 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 6223 prodotti di "Apoptosi"
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Inauhzin
CAS:Inauhzin (INZ) reactivates p53, inhibits SIRT1, induces Y cell apoptosis without genotoxic stress (IC50=3 uM in A549).Formula:C25H19N5OS2Purezza:98% - 99.36%Colore e forma:SolidPeso molecolare:469.58Tenovin-6 Hydrochloride
CAS:Tenovin-6 HCl: Inhibits SIRT1 (21µM), SIRT2 (10µM), HDAC8; potent p53 activator.Formula:C25H35ClN4O2SPurezza:99.36%Colore e forma:SolidPeso molecolare:491.09Ref: TM-T8480
1mg39,00€2mg51,00€5mg70,00€1mL*10mM (DMSO)73,00€10mg88,00€25mg140,00€50mg226,00€100mg376,00€S-(5'-Adenosyl)-L-methionine tosylate
CAS:S-(5'-Adenosyl)-L-methionine tosylate (SAMe) is a ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNAFormula:C22H30N6O8S2Purezza:80% - 98.18%Colore e forma:SolidPeso molecolare:570.64Azoramide
CAS:Azoramide, a small-molecule modulator, has the antidiabetic activity of unfolded protein response.Formula:C15H17ClN2OSPurezza:99.08% - 99.85%Colore e forma:SolidPeso molecolare:308.83Thalidomide-5-methyl
CAS:Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand. Thalidomide-5-methyl is used in the recruitment of CRBN protein.Formula:C14H12N2O4Purezza:99.48%Colore e forma:SolidPeso molecolare:272.26Ref: TM-T40503
1mg65,00€1mL*10mM (DMSO)130,00€5mg144,00€10mg210,00€25mg359,00€50mg504,00€100mg680,00€200mg919,00€AZD3759 hydrochloride
CAS:AZD3759 hydrochloride is an oral, CNS-penetrant EGFR inhibitor with IC50s of 0.2/0.3/0.2 nM.Formula:C22H24Cl2FN5O3Purezza:99.62%Colore e forma:SolidPeso molecolare:496.36Ref: TM-T4249
2mg34,00€5mg46,00€1mL*10mM (DMSO)49,00€10mg62,00€25mg94,00€50mg167,00€100mg265,00€200mg385,00€Ciprofloxacin hydrochloride monohydrate
CAS:Ciprofloxacin hydrochloride monohydrate (Bay-09867 hydrochloride monohydrate) is a fluoroquinolone antibiotic with potent antibacterial activity.
Formula:C17H21ClFN3O4Purezza:99.23% - 99.85%Colore e forma:White Or Yellowish Crystalline PowderPeso molecolare:385.82Laquinimod
CAS:Laquinimod (LAQ) is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral
Formula:C19H17ClN2O3Purezza:98.42% - 98.84%Colore e forma:SolidPeso molecolare:356.8Tenovin-3
CAS:Tenovin-3 acts as a p53 activator.Formula:C18H21N3OSPurezza:99.72% - ≥95%Colore e forma:SolidPeso molecolare:327.44Demethoxycurcumin
CAS:Demethoxycurcumin: antioxidant, anti-inflammatory, anti-proliferative, anti-acanthamoebic, enhances chemo for resistant cancers, inhibits cancer pathways.Formula:C20H18O5Purezza:94.54% - 99.86%Colore e forma:SolidPeso molecolare:338.35Ref: TM-T6S1683
5mg42,00€10mg52,00€1mL*10mM (DMSO)52,00€25mg88,00€50mg149,00€100mg212,00€200mg314,00€A-419259
CAS:A-419259 (RK-20449) is an apoptosis inducer that selectively inhibits the Src family of kinases, including Src,LCK, and Lyn, with an IC50=3 to 9 nM.Formula:C29H34N6OPurezza:99.48%Colore e forma:SolidPeso molecolare:482.62Ro-3306
CAS:RO-3306: ATP-competitive CDK1 inhibitor, Ki 20 nM, >15x more selective than other human kinases.Formula:C18H13N3OS2Purezza:97.67% - 99.79%Colore e forma:SolidPeso molecolare:351.45PKD-IN-1 dihydrochloride (956121-30-5 free base)
CAS:CRT0066101 dihydrochloride is an inhibitor of PKD.Formula:C18H21Cl3N4OPurezza:99.5%Colore e forma:SolidPeso molecolare:415.75Tauroursodeoxycholate
CAS:Tauroursodeoxycholate (UR 906), a hydrophilic bile acid, low in humans, may treat PBC, insulin resistance, and ALS.Formula:C26H45NO6SPurezza:98.77% - 99.93%Colore e forma:White SolidPeso molecolare:499.7PEAQX
CAS:PEAQX (NVP-AAM077) is an oral NMDA antagonist, inhibits 1A/2A receptors (IC50: 270 nM), less so 1A/2B (IC50: 29,600 nM).Formula:C17H17BrN3O5PPurezza:98% - 99.9%Colore e forma:SolidPeso molecolare:454.21Ref: TM-T4171
1mg33,00€2mg43,00€5mg71,00€1mL*10mM (DMSO)92,00€10mg118,00€25mg205,00€50mg319,00€100mg445,00€200mg643,00€AR42
CAS:AR42 (OSU-HDAC42) is an HDAC inhibitor (IC50: 30 nM).Formula:C18H20N2O3Purezza:98.46% - 98.96%Colore e forma:SolidPeso molecolare:312.36Ref: TM-T6392
1mg38,00€5mg80,00€1mL*10mM (DMSO)88,00€10mg120,00€25mg236,00€50mg385,00€100mg587,00€200mg825,00€Emricasan
CAS:Emricasan (IDN-6556) is a pan-caspase inhibitor with irreversible properties.Formula:C26H27F4N3O7Purezza:98.13% - 99%Colore e forma:SolidPeso molecolare:569.5Aloperine
CAS:Aloperine exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.Formula:C15H24N2Purezza:98% - 99.88%Colore e forma:Yellow Crystalline PowderPeso molecolare:232.361400W dihydrochloride
CAS:1400W dihydrochloride (N-(3-(Aminomethyl)benzyl)acetamidine) is a highly effective and specific inhibitor of inducible NOS2 (iNOS).Formula:C10H17Cl2N3Purezza:98% - 99.94%Colore e forma:SolidPeso molecolare:250.17Ref: TM-T3491
5mg48,00€1mL*10mM (DMSO)50,00€10mg71,00€25mg118,00€50mg207,00€100mg354,00€200mg460,00€500mg747,00€Bilobalide
CAS:Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations.Formula:C15H18O8Purezza:98.81% - 99.92%Colore e forma:White SolidPeso molecolare:326.30Ipatasertib
CAS:Ipatasertib (GDC-0068) is a selective, ATP-competitive pan-Akt inhibitor that can lead to p53-independent PUMA activation.Cost-effective and quality-assured.Formula:C24H32ClN5O2Purezza:98.28% - 99.79%Colore e forma:SolidPeso molecolare:458Sulforaphane
CAS:Sulforaphane is a natural isothiocyanate that activates Nrf2. Sulforaphane has antitumor and anti-inflammatory activities. Cost-effective and quality-assured.Formula:C6H11NOS2Purezza:95% - 99.79%Colore e forma:Light Yellow LiquidPeso molecolare:177.29Nω-Hydroxy-nor-L-Arginine Dihydrochloride
CAS:Nω-Hydroxy-nor-L-Arginine Dihydrochloride is a competitive and reversible inhibitor of arginaseFormula:C5H14Cl2N4O3Purezza:99.12% - 99.84%Colore e forma:SolidPeso molecolare:249.10Ref: TM-T9096
500mgPrezzo su richiesta1mg38,00€2mg50,00€5mg84,00€10mg116,00€25mg225,00€50mg335,00€100mg469,00€ZZW-115 hydrochloride
CAS:ZZW-115 hydrochloride inhibits the activity of NUPR1.Formula:C24H34Cl3F3N4SPurezza:99.97%Colore e forma:SolidPeso molecolare:573.97Ref: TM-T9465
1mg87,00€5mg178,00€1mL*10mM (DMSO)233,00€10mg281,00€25mg480,00€50mg692,00€100mg973,00€500mg1.945,00€Chromium picolinate
CAS:Chromium picolinate causes DNA damage and mutation. It is an activator of p38.Formula:C18H12CrN3O6Purezza:99.64%Colore e forma:Violet-Red Crystalline PowderPeso molecolare:418.30Thalidomide-NH-PEG1-NH2 hydrochloride
CAS:Thalidomide-NH-PEG1-NH2 hydrochloride (4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl) is a synthetic E3 ligase ligand-Formula:C17H21ClN4O5Purezza:97.13%Colore e forma:SolidPeso molecolare:396.83Trolox
CAS:Trolox is a vitamin E analogue, used in reducing oxidative stress or damage.Formula:C14H18O4Purezza:98.90% - 99.90%Colore e forma:White To Fainly Beige Crystalline PowderPeso molecolare:250.29Thalidomide-NH-CH2-COOH
CAS:Thalidomide-NH-CH2-COOH ((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine) is a synthesized E3 ligase ligand-linker conjugate containing aFormula:C15H13N3O6Purezza:96.3800%Colore e forma:SolidPeso molecolare:331.28Tetrahydroxyquinone monohydrate
CAS:Anticataract compound; redox-active; forms ROS via semiquinone radical cycle.Formula:C6H6O7Colore e forma:SolidPeso molecolare:190.11Apocynin
CAS:Apocynin (NSC 2146) is a specific NADPH-oxidase inhibitor (IC50: 10 μM).Formula:C9H10O3Purezza:99.71% - 99.98%Colore e forma:Yellowish To Brown PowderPeso molecolare:166.17Alda-1
CAS:Alda-1 activates ALDH2*1 and ALDH2*2, permeates cells, and targets mitochondrial aldehyde dehydrogenase 2.Formula:C15H11Cl2NO3Purezza:98.5% - 99.63%Colore e forma:SolidPeso molecolare:324.16Ref: TM-T2662
5mg39,00€10mg58,00€1mL*10mM (DMSO)64,00€25mg73,00€50mg93,00€100mg147,00€200mg185,00€500mg419,00€Metamizole magnesium
CAS:Metamizole magnesium (Metamizolemagnesiumsalt) is a pain reliever, which can antispasmodic.Formula:C26H32MgN6O8S2Purezza:93.51%Colore e forma:SolidPeso molecolare:645.01ARRY 520 hydrochloride
CAS:'ARRY 520 hydrochloride: a KSP inhibitor causing apoptosis and strong anti-proliferative effects.'Formula:C20H23ClF2N4O2SPurezza:98.06% - 99.62%Colore e forma:SolidPeso molecolare:456.94Ref: TM-TQ0318L
1mg59,00€5mg116,00€1mL*10mM (DMSO)149,00€10mg170,00€25mg304,00€50mg437,00€100mg615,00€200mg830,00€Eltrombopag Olamine
CAS:Eltrombopag Olamine (Eltrombopag diethanolamine salt) is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietinFormula:C29H36N6O6Purezza:99.59% - 99.89%Colore e forma:SolidPeso molecolare:564.63Ref: TM-T6825
2mg40,00€5mg60,00€1mL*10mM (DMSO)86,00€10mg95,00€25mg133,00€50mg168,00€100mg217,00€200mg323,00€500mg533,00€HA15
CAS:HA15 targets BiP/GRP78/HSPA5, showing anti-cancer effects on all tested melanoma cells, resistant or patient-derived.Formula:C23H22N4O3S2Purezza:99.77% - 99.86%Colore e forma:SolidPeso molecolare:466.58Ref: TM-T6855
1mg35,00€2mg48,00€5mg72,00€1mL*10mM (DMSO)74,00€10mg96,00€25mg187,00€50mg283,00€100mg439,00€ISRIB (trans-isomer)
CAS:ISRIB (trans-isomer) is a potent inhibitor of PERK that rescues protein translation and prevents SG formation in the presence of P-eIF2α. Cost effective and quality assured.Formula:C22H24Cl2N2O4Purezza:97.86% - 99.27%Colore e forma:SolidPeso molecolare:451.34Thalidomide 4-fluoride
CAS:Thalidomide 4-fluoride (E3 ligase Ligand 4) (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand.Formula:C13H9FN2O4Purezza:99.12%Colore e forma:SolidPeso molecolare:276.22Thalidomide-O-amido-C6-NH2 hydrochloride
CAS:Thalidomide-O-amido-C6-NH2 HCl, a cereblon ligand-linker for PROTAC synthesis.Formula:C21H27ClN4O6Purezza:97.33%Colore e forma:SolidPeso molecolare:466.915CA-4948
CAS:CA-4948 (Emavusertib) is a potent IRAK4/FLT3 inhibtor. CA-4948 with anti-tumor activity.Formula:C24H25N7O5Purezza:99.35% - 99.88%Colore e forma:SolidPeso molecolare:491.5Ref: TM-T9027
1mg34,00€2mg49,00€5mg73,00€1mL*10mM (DMSO)79,00€10mg93,00€25mg166,00€50mg295,00€100mg507,00€Tenovin-6
CAS:Tenovin-6 is a p53 transcriptional activity agonist.Formula:C25H34N4O2SPurezza:98.89% - >99.99%Colore e forma:SolidPeso molecolare:454.63Ref: TM-T1818
1mg40,00€2mg52,00€5mg73,00€1mL*10mM (DMSO)74,00€10mg93,00€25mg148,00€50mg219,00€100mg371,00€500mg882,00€Dacarbazine citrate
CAS:Dacarbazine citrate treats lymphatic cancers, malignant melanoma, islet cell carcinoma, and soft tissue sarcoma.Formula:C12H18N6O8Colore e forma:SolidPeso molecolare:374.31FOXO4-DRI acetate
FOXO4-DRI acetate is a bioactive chemical.Formula:C36H64N14O14SPurezza:99.10%Colore e forma:SolidPeso molecolare:5358.06Periplocin
CAS:Periplocin fights lung cancer, induces apoptosis, stunts growth via beta-catenin/Tcf, and treats rheumatoid arthritis/traditional ailments.Formula:C36H56O13Purezza:99.66% - 99.74%Colore e forma:SolidPeso molecolare:696.82Ref: TM-T5S1982
1mg35,00€5mg77,00€10mg106,00€1mL*10mM (DMSO)107,00€25mg170,00€50mg253,00€100mg375,00€500mg892,00€TrxR1-IN-B19
CAS:TrxR1-IN-B19 (TrxR1 IN B19), a TrxR1 inhibitor, selectively kills gastric cancer cells by a small molecule via targeting TrxR1 and ROS-mediated ER stressFormula:C21H22O5Purezza:98.6%Colore e forma:SolidPeso molecolare:354.4Ref: TM-T29017
1mg92,00€2mg109,00€5mg161,00€1mL*10mM (DMSO)170,00€10mg256,00€25mg420,00€50mg587,00€100mg793,00€200mg1.063,00€Thalidomide-O-amido-C3-NH2 TFA
CAS:Thalidomide-based E3 ligase linker for PROTAC tech; cereblon ligand conjugate.Formula:C20H21F3N4O8Purezza:98.47%Colore e forma:SolidPeso molecolare:502.4Thalidomide-O-COOH
CAS:Thalidomide-O-COOH is a Cereblon ligand for CRBN protein recruitment and PROTAC construction with a linker.Formula:C15H12N2O7Purezza:98% - 98.29%Colore e forma:SolidPeso molecolare:332.27Methoxychlor
CAS:Methoxychlor, an organochlorine pesticide, is thought to be an endocrine disrupter that affects Ca2 homeostasis and cell viability in different cell models.Formula:C16H15Cl3O2Purezza:98.82% - ≥95%Colore e forma:Colorless Crystals (Technical Grey Powder) To The Environment Immediate Steps Should Be Taken To Limit Its Spread To The Environment IfPeso molecolare:345.65Liproxstatin-1 hydrochloride
CAS:Liproxstatin-1 hydrochloride is a high-potency ferroptosis inhibitor capable of effectively preventing ferroptotic cell death, with an IC50 value of 22 nM [1].Formula:C19H22Cl2N4Colore e forma:SolidPeso molecolare:377.31GSK778 hydrochloride
CAS:GSK778 hydrochloride is a selective BET BD1 bromodomain inhibitor, with IC50s ranging from 41 to 143 nM, effective in cancer models.Formula:C30H34ClN5O3Purezza:97.26% - 98.35%Colore e forma:SolidPeso molecolare:548.08Ref: TM-T9703L
1mg109,00€5mg235,00€1mL*10mM (DMSO)303,00€10mg349,00€25mg532,00€50mg745,00€100mg999,00€Thalidomide-4-OH
CAS:Thalidomide-4-OH, a Thalidomide-derived Cereblon binder, recruits CRBN and serves as a PROTAC linker.Formula:C13H10N2O5Purezza:99.59%Colore e forma:SolidPeso molecolare:274.23
