Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(1 prodotti)
- Caspasi(154 prodotti)
- FOXO1(2 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(135 prodotti)
- PDK(9 prodotti)
- PERK(23 prodotti)
- Chinasi di serina/treonina(17 prodotti)
- Survivin(14 prodotti)
- TNF(93 prodotti)
- c-RET(61 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 6225 prodotti di "Apoptosi"
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Sulindac sodium
CAS:Sulindac (sodium) (MK-231) is an NSAID used for arthritis pain, swelling, gout, and as an immunomodulator in CRC therapy.Formula:C20H16FNaO3SColore e forma:SolidPeso molecolare:378.39DCH36_06
CAS:DCH36_06 ((5E)-1-(3-chloro-4-methylphenyl)-5-[(2E)-3-(furan-2-yl)prop-2-en-1-ylidene]-2-thioxodihydropyrimidine-4,6(1H,5H)-dione) as a bona fide is a potentFormula:C18H13ClN2O3SPurezza:97.78%Colore e forma:SolidPeso molecolare:372.83Ref: TM-T9373
1mg39,00€5mg85,00€1mL*10mM (DMSO)89,00€10mg123,00€25mg240,00€50mg386,00€100mg615,00€200mg827,00€Onvansertib
CAS:Onvansertib (NMS-1286937) is a PLK1 inhibitor with high selectivity and oral activity. Onvansertib has antitumor activity. Cost-effective and quality-assured.Formula:C24H27F3N8O3Purezza:98.3% - 99.88%Colore e forma:SolidPeso molecolare:532.52Ref: TM-T6247
1mg34,00€5mg66,00€1mL*10mM (DMSO)78,00€10mg93,00€25mg142,00€50mg215,00€100mg356,00€500mg747,00€Tofacitinib
CAS:Tofacitinib (Tasocitinib) is an orally Janus kinase inhibitor. Tofacitinib is used for the treatment of rheumatoid arthritis. Cost effective and quality assured.Formula:C16H20N6OPurezza:99% - >99.99%Colore e forma:SolidPeso molecolare:312.37Fenobam hydrate
CAS:Fenobam hydrate blocks mGluR5, preventing calcium mobilization, and may reduce stress, anxiety, and pain.Formula:C11H13ClN4O3Colore e forma:SolidPeso molecolare:284.7Benidipine
CAS:Benidipine: potent oral calcium blocker, boosts nitric oxide synthase, enhances coronary flow, protects heart cells post-ischemia.Formula:C28H31N3O6Colore e forma:SolidPeso molecolare:505.56Amuvatinib
CAS:Amuvatinib (MP470) is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity.Formula:C23H21N5O3SPurezza:99.38% - >99.99%Colore e forma:SolidPeso molecolare:447.51D-Pantothenic acid sodium
CAS:D-Pantothenic acid sodium, a sodium salt of D-pantothenate, is a vital B5 derivative, aiding fat, carb, and amino acid oxidation.Formula:C9H16NNaO5Purezza:97.98%Colore e forma:White PowderPeso molecolare:241.22β-mangostin
CAS:β-Mangostin: a xanthone in Cratoxylum arborescens, fights bacteria, malaria, tuberculosis (MIC 6.25μg/mL), and cancer.Formula:C25H28O6Purezza:98.01% - 99.97%Colore e forma:Faintly Yellow PowderPeso molecolare:424.49EPI-001
CAS:EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ～6 μM and a selective PPAR-gamma modulator.Formula:C21H27ClO5Purezza:99% - 99.67%Colore e forma:SolidPeso molecolare:394.89Ref: TM-T6829
2mg34,00€5mg48,00€1mL*10mM (DMSO)49,00€10mg73,00€25mg120,00€50mg192,00€100mg286,00€200mg425,00€7,8-Dihydroxyflavone
CAS:7,8-Dihydroxyflavone (7,8-DHF) is a naturally-occurring flavone and exist in Tridax procumbens, Godmania aesculifolia, and primula tree leaves.Formula:C15H10O4Purezza:98.48% - 99.81%Colore e forma:SolidPeso molecolare:254.24Chelerythrine chloride
CAS:Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect toFormula:C21H18ClNO4Purezza:95% - 99.19%Colore e forma:Yellow To Orange SolidPeso molecolare:383.83Ref: TM-T3419
2mg34,00€5mg50,00€1mL*10mM (DMSO)65,00€10mg84,00€25mg145,00€50mg205,00€100mg289,00€200mg432,00€Tomivosertib HCl
CAS:Tomivosertib (eFT508) is a MNK1/2 inhibitor that blocks eIF4E phosphorylation, hindering tumor growth and immune signaling.Formula:C17H21ClN6O2Colore e forma:SolidPeso molecolare:376.845YUM70
CAS:YUM70 inhibits GRP78 (IC50: 1.5μM), inducing ER stress and apoptosis in pancreatic cancer.Formula:C21H19ClN2O4Purezza:97.25%Colore e forma:SolidPeso molecolare:398.84Ref: TM-T8901
1mg46,00€1mL*10mM (DMSO)90,00€5mg92,00€10mg128,00€25mg250,00€50mg369,00€100mg525,00€200mg710,00€INH6
CAS:INH6, an effective Hec1 inhibitor, selectively disrupts the Hec1/Nek2 interaction and induces chromosome mis-alignment.Formula:C19H18N2OSPurezza:98.81%Colore e forma:SolidPeso molecolare:322.42Trigonelline
CAS:Trigonelline (Trigenolline), an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.Formula:C7H7NO2Purezza:97.585% - 99.49%Colore e forma:Prisms Aqueous From Alcohol + Water SolidPeso molecolare:137.14Lanreotide acetate
CAS:Lanreotide acetate (BIM 23014 acetate) is a somatostatin analogue with antineoplastic activity, used for carcinoid syndromeFormula:C56H73N11O12S2Purezza:>99.99%Colore e forma:SolidPeso molecolare:1156.39Tetramethylcurcumin
CAS:Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it alsoFormula:C25H28O6Purezza:97.69% - 99.94%Colore e forma:SolidPeso molecolare:424.49Ivachtin
CAS:Ivachtin (Caspase-3 Inhibitor VII) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor(IC50 = 23 nM) and is a modest inhibitor of the remainingFormula:C20H21N3O7SPurezza:99.74%Colore e forma:SolidPeso molecolare:447.46Tauroursodeoxycholate sodium
CAS:Tauroursodeoxycholate sodium (TUDC) is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis.Formula:C26H44NNaO6SPurezza:97.90%Colore e forma:SolidPeso molecolare:521.69Cinobufagin
CAS:Cinobufagin (Cinobufagine) is a selective Na+/K+-ATPase inhibitor. The activity of Cinobufagin is same as ouabain.Formula:C26H34O6Purezza:97.77% - 99.97%Colore e forma:SolidPeso molecolare:442.54Ref: TM-T3432
1mg49,00€5mg90,00€1mL*10mM (DMSO)90,00€10mg137,00€25mg203,00€50mg281,00€100mg439,00€500mg954,00€CHIR-124
CAS:CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM). It has 2, 000-fold selectivity against Chk2, 500- to 5, 000-fold less activity against Cdc2 and CDK2/4.Formula:C23H22ClN5OPurezza:96.33% - 98.35%Colore e forma:SolidPeso molecolare:419.91Ref: TM-T6350
1mg39,00€2mg49,00€5mg77,00€1mL*10mM (DMSO)82,00€10mg99,00€25mg161,00€50mg227,00€100mg339,00€Euphorbia Factor L2
CAS:Euphorbia Factor L2 alleviates lipopolysaccharide-induced acute lung injury and inflammation through inhibits NF-κB activation.Formula:C38H42O9Purezza:99.53% - 99.96%Colore e forma:SolidPeso molecolare:642.73LYN-1604 dihydrochloride
CAS:LYN-1604 is a novel ULK1 activator.It inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.Formula:C33H45Cl4N3O2Purezza:98.95% - 99.92%Colore e forma:SolidPeso molecolare:657.54Ref: TM-T8808L
1mg35,00€5mg78,00€1mL*10mM (DMSO)101,00€10mg117,00€25mg212,00€50mg316,00€100mg447,00€200mg628,00€AZD1208 hydrochloride
CAS:AZD1208 hydrochloride is a highly selective, potent and orally active PIM inhibitor.Formula:C21H22ClN3O2SColore e forma:SolidPeso molecolare:415.94Maduramicin ammonium
CAS:Maduramicin ammonium (Maduramycin Ammonium) is an anticoccidial agent for the the treatment of Eimeria spp., E.Formula:C47H83NO17Purezza:99.83%Colore e forma:White Crystalline PowderPeso molecolare:934.20OSU-T315
CAS:OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.Formula:C30H30F3N5OPurezza:98.69%Colore e forma:SolidPeso molecolare:533.59Ref: TM-T5485
1mg88,00€5mg187,00€1mL*10mM (DMSO)220,00€10mg298,00€25mg533,00€50mg755,00€100mg1.008,00€200mg1.359,00€M50054
CAS:Apoptosis Inhibitor was a novel inhibitor of programmed cell death associate with caspase-3 inhibition.Formula:C13H16O4Purezza:97.8%Colore e forma:SolidPeso molecolare:236.26SBE13 Hydrochloride
CAS:SBE13 Hydrochloride (SBE 13 HCl) is an effective and specific PLK1 inhibitor (IC50: 0.2 nM); no inhibition om Aurora A kinase, Plk2/3.Formula:C24H28Cl2N2O4Purezza:99.00% - ≥95%Colore e forma:SolidPeso molecolare:479.4Moexipril hydrochloride
CAS:Moexipril hydrochloride (Moexipril HCl) is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment ofFormula:C27H34N2O7·HClPurezza:97.8%Colore e forma:A Fine White To Off-White PowderPeso molecolare:535.03Pinosylvin
CAS:Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.Formula:C14H12O2Purezza:99.89% - 99.91%Colore e forma:SolidPeso molecolare:212.24Meisoindigo
CAS:Meisoindigo (Natura-α) is a derivative of indigo natural, might induces apoptosis and myeloid differentiation of acute myeloid leukemia (AML).Formula:C17H12N2O2Purezza:98.03% - 98.19%Colore e forma:SolidPeso molecolare:276.29Coenzyme Q9
CAS:Coenzyme Q9 (Ubiquinone 9) (CoQ9) is a normal constituent of human plasma.Formula:C54H82O4Purezza:98.2% - 99.47%Colore e forma:SolidPeso molecolare:795.23T-1101 tosylate
CAS:T-1101 tosylate (TAI-95 tosylate) is an inhibitor of Hec1/Nek2, with antitumor activity.Formula:C31H31N5O6S3Purezza:98.1%Colore e forma:SolidPeso molecolare:665.8Ref: TM-T8216
2mg39,00€5mg58,00€1mL*10mM (DMSO)86,00€10mg93,00€25mg137,00€50mg222,00€100mg371,00€200mg530,00€PF-573228
CAS:PF-573228 is an ATP-competitive FAK inhibitor. In a cell-free assay, the IC50 of FAK is 4 nM.Formula:C22H20F3N5O3SPurezza:96.58% - 99.51%Colore e forma:SolidPeso molecolare:491.49Polyphyllin VI
CAS:1. Polyphyllin VI has hemostasis , expectorant , bacteriostasis, anticytotoxic, anti pregnancy kill sperm effects.Formula:C39H62O13Purezza:99.69% - 99.72%Colore e forma:SolidPeso molecolare:738.90Ref: TM-T6S2315
1mg37,00€5mg71,00€10mg90,00€1mL*10mM (DMSO)103,00€25mg147,00€50mg208,00€100mg309,00€200mg447,00€Citric acid monohydrate
CAS:Citric Acid Monohydrate: tricarboxylic, from citrus, antioxidant, stabilizes drugs, preservative.Formula:C6H10O8Purezza:99.78% - 99.87%Colore e forma:White Solid CrystallinePeso molecolare:210.14Protosappanin B
CAS:Protosappanin B enhances cell survival, growth protein 43; degrades p53 via MDM2 ubiquitination.Formula:C16H16O6Purezza:98% - 98.86%Colore e forma:SolidPeso molecolare:304.29Fosbretabulin Disodium
CAS:Fosbretabulin Disodium (CA 4P), a water-soluble prodrug of Combretastatin A4 (CA4), is a microtubule-targeting agent that binds β-tubulin (Kd: 0.4 μM).Formula:C18H19O8P·2NaPurezza:97.43% - 99.96%Colore e forma:White SolidPeso molecolare:440.29TCS JNK 5a
CAS:TCS JNK 5a (SC202671) is an effective, specific inhibitor of JNK3(pIC50= 6.7), JNK2(pIC50=6.5).Formula:C20H16N2OSPurezza:99.22% - 99.51%Colore e forma:SolidPeso molecolare:332.42PF-3758309 dihydrochloride
PF-3758309 dihydrochloride is a potent PAK4 inhibitor (Kd = 2.7 nM, Ki = 18.7 nM), oral, ATP-competitive; blocks cell growth, induces apoptosis.Formula:C25H32Cl2N8OSColore e forma:SolidPeso molecolare:563.55Voreloxin hydrochloride
CAS:Voreloxin hydrochloride (SNS-595 hydrochloride) is a potent inhibitor of Topoisomerase II with broad-spectrum anti-tumor activity.Formula:C18H20ClN5O4SPurezza:99.84%Colore e forma:SolidPeso molecolare:437.9Ripretinib
CAS:Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.Formula:C24H21BrFN5O2Purezza:99.07% - 99.62%Colore e forma:SolidPeso molecolare:510.36Ref: TM-T8482
1mg71,00€2mg92,00€5mg157,00€1mL*10mM (DMSO)192,00€10mg260,00€25mg409,00€50mg655,00€100mg1.063,00€200mg1.459,00€Prexasertib dihydrochloride
CAS:Prexasertib dihydrochloride (LY2606368) inhibits CHK1 (Ki: 0.9 nM); IC50: CHK2 8 nM, RSK 9 nM.Formula:C18H21Cl2N7O2Purezza:98.46% - 99.82%Colore e forma:SolidPeso molecolare:438.31Ref: TM-T4327
1mg43,00€2mg56,00€5mg93,00€1mL*10mM (DMSO)96,00€10mg137,00€25mg259,00€50mg405,00€100mg597,00€500mg1.251,00€Prosapogenin A
CAS:Prosapogenin A (Progenin III) has anticancer activity.Formula:C39H62O12Purezza:99.60% - 99.75%Colore e forma:SolidPeso molecolare:722.90Ref: TM-T5S1252
1mg46,00€5mg92,00€1mL*10mM (DMSO)148,00€10mg152,00€25mg250,00€50mg371,00€100mg530,00€Atezolizumab
CAS:Atezolizumab is an antibody inhibitor, a humanized monoclonal antibody, IgG1, which targets PD-L1. Atezolizumab has antitumor effect. Cost-effective and quality-assured.Purezza:95.10% - 99.3% （SEC-HPLC）Colore e forma:LiquidPeso molecolare:144.6 kDaSophoraflavanone G
CAS:Sophoraflavanone G (Kushenol F) (Kushenol F), isolated from Sophora flavescens, induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-relatedFormula:C25H28O6Purezza:97.09% - 99.77%Colore e forma:SolidPeso molecolare:424.49Importazole
CAS:Importazole is an inhibitor of the nuclear transport receptor importin-β.Formula:C20H22N4Purezza:99.6% - >99.99%Colore e forma:SolidPeso molecolare:318.42Ref: TM-T3445
5mg49,00€1mL*10mM (DMSO)54,00€10mg69,00€25mg144,00€50mg215,00€100mg356,00€200mg532,00€500mg852,00€3,4-Dicaffeoylquinic acid
CAS:3,4-Dicaffeoylquinic acid (Isochlorogenic acid B) has antioxidant activity.Formula:C25H24O12Purezza:96.33% - 98.82%Colore e forma:SolidPeso molecolare:516.45Ref: TM-T6S1525
1mg40,00€5mg80,00€10mg101,00€1mL*10mM (DMSO)103,00€25mg167,00€50mg240,00€100mg355,00€500mg845,00€
