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Apoptosi

Apoptosi

Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.

Sottocategorie di "Apoptosi"

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Trovati 5599 prodotti di "Apoptosi"

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  • Mitochonic Acid 35

    CAS:
    <p>Mitochonic Acid 35 is a dual TNF-α and TGF-β1 inhibitor that acts by inhibiting IκB kinase phosphorylation and Smad3 phosphorylation.</p>
    Formula:C19H19NO5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:341.36
  • Mcl-1 inhibitor 10

    CAS:
    <p>Mcl-1 inhibitor10 (compound 43) is a relatively potent MCL-1 inhibitor with an IC50 of 0.67 μM. It interacts with a specific binding site on the MCL-1 protein, disrupting its pro-survival signals and inducing apoptosis in cancer cells. This compound is useful for research on MCL-1-dependent cancers.</p>
    Formula:C21H15F3O4
    Colore e forma:Solid
    Peso molecolare:388.34
  • (S)-Elobixibat

    CAS:
    <p>(S)-Elobixibat is the S-isomer of Elobixibat. It is an orally active inhibitor of Apical Sodium-Dependent Bile (IBAT) and can reduce LDL cholesterol, increase serum GLP-1, and promote colonic motility. This compound shows potential for treating metabolic syndrome and can be studied for constipation, dyslipidemia, non-alcoholic hepatitis, and liver tumors.</p>
    Formula:C36H45N3O7S2
    Colore e forma:Solid
    Peso molecolare:695.89
  • ABD56

    CAS:
    <p>ABD56 inhibits osteoclast formation and activity in vitro and in vivo.</p>
    Formula:C17H18O3
    Colore e forma:Solid
    Peso molecolare:270.32
  • Rooperol

    CAS:
    <p>Rooperol: a norlignan with p38α inhibiting, immunomodulatory, antitumor, antibacterial, anticonvulsant, and antioxidant properties.</p>
    Formula:C17H14O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:282.29
  • MBC-11

    CAS:
    <p>MBC-11: First bone-targeting bisphosphonate-etidronate conjugate with araC, may treat TIBD.</p>
    Formula:C11H20N3O14P3
    Purezza:>99.99% - >99.99%
    Colore e forma:Solid
    Peso molecolare:511.21
  • PDMP (hydrochloride)

    CAS:
    <p>PDMP, a glucosylceramide synthase inhibitor with 4 stereoisomers, acts at 0.8μM; D-threo enantiomer also blocks lactosylceramide synthesis.</p>
    Formula:C23H39ClN2O3
    Colore e forma:Solid
    Peso molecolare:427.03
  • BP-1-108

    CAS:
    <p>BP-1-108 is a potent and selective STAT5 inhibitor.</p>
    Formula:C32H38N2O6S
    Colore e forma:Solid
    Peso molecolare:578.72
  • HDAC-IN-42

    CAS:
    <p>HDAC-IN-42, a potent HDAC inhibitor: IC50 - 0.19μM (HDAC1), 4.98μM (HDAC6); halts cancer cell growth, triggers apoptosis &amp; G2/M arrest.</p>
    Formula:C20H15NO7
    Colore e forma:Solid
    Peso molecolare:381.34
  • CS1

    CAS:
    <p>CS1: potent topoisomerase II alpha inhibitor, broad-spectrum antitumor, low toxicity, anti-resistance, induces DNA damage, G2/M arrest, apoptosis.</p>
    Formula:C16H12O3
    Colore e forma:Solid
    Peso molecolare:252.26
  • DNA topoisomerase II inhibitor 1

    CAS:
    <p>Potent DNA topoisomerase II blocker; arrests cell cycle, induces apoptosis, anti-growth effects.</p>
    Formula:C28H24N4O3S
    Colore e forma:Solid
    Peso molecolare:496.58
  • MDM2/XIAP-IN-3

    CAS:
    <p>MDM2/XIAP-IN-3 (compound 3e), a dual inhibitor of MDM2/XIAP, diminishes MDM2 and XIAP protein levels while augmenting p53 expression, consequently suppressing</p>
    Formula:C29H30N2O5S
    Colore e forma:Solid
    Peso molecolare:518.62
  • EGFR/BRAFV600E-IN-1

    CAS:
    <p>EGFR/BRAFV600E-IN-1 inhibits EGFR (0.08 μM) &amp; BRAFV600E (0.15 μM), affects A-549, MCF-7, Panc-1 &amp; HT-29 (IC50: 0.79-1.3 μM).</p>
    Formula:C24H24ClN3O3
    Colore e forma:Solid
    Peso molecolare:437.92
  • RETRA

    CAS:
    <p>RETRA is an agent of anticancer that acts by exerting anticancer activity in Ewing's sarcoma cells independent of their TP53 status.</p>
    Formula:C11H12BrNO3S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:350.25
  • A-802715

    CAS:
    <p>A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases the</p>
    Formula:C16H26N4O3
    Purezza:96.29%
    Colore e forma:Solid
    Peso molecolare:322.4
  • VEGFR-2-IN-22

    CAS:
    <p>VEGFR-2-IN-22 blocks VEGFR-2/beta-tubulin, IC50=19.82 nM, induces apoptosis.</p>
    Formula:C26H24ClFN4O6
    Colore e forma:Solid
    Peso molecolare:542.94
  • c-Fms-IN-12

    CAS:
    <p>c-Fms-IN-12 inhibits FMS/c-KIT, triggers A549 cell apoptosis, and has potential as a multi-cancer therapy.</p>
    Formula:C30H32N6O6
    Colore e forma:Solid
    Peso molecolare:572.61
  • NSC 107512

    CAS:
    <p>NSC 107512, a sangivamycin-like molecule, inhibits CDK9, curbing myeloma growth and triggering cell death.</p>
    Formula:C12H16N6O5
    Colore e forma:Solid
    Peso molecolare:324.29
  • n-Octyl caffeate

    CAS:
    <p>n-Octyl caffeate demonstrates anti-cancer and apoptosis-inducing properties in highly liver-metastatic murine colon 26-L5 carcinoma cell lines.</p>
    Formula:C17H24O4
    Colore e forma:Solid
    Peso molecolare:292.37
  • TL02-59 dihydrochloride

    CAS:
    <p>TL02-59 dihydrochloride is an orally active inhibitor of Src-family kinase Fgr (IC50: 0.03 nM).</p>
    Formula:C32H36Cl2F3N5O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:682.56