Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(3 prodotti)
- Caspasi(153 prodotti)
- FOXO1(2 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(92 prodotti)
- PDK(9 prodotti)
- PERK(26 prodotti)
- Chinasi di serina/treonina(18 prodotti)
- Survivin(14 prodotti)
- TNF(49 prodotti)
- c-RET(60 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 6026 prodotti di "Apoptosi"
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PARP1-IN-15
PARP1-IN-15 (Compound 6) is a PARP1 inhibitor that also inhibits tankyrase (TNKS) and promotes DNA double-strand breaks, leading to tumor cell apoptosis.Formula:C16H12N2O2Purezza:98%Colore e forma:SolidPeso molecolare:264.28A011
A011, a potent and selective ataxia-telangiectasia mutated (ATM) inhibitor, exhibits an IC50 of 1.0 nM and triggers apoptosis as well as G2/M phase cell cycleFormula:C27H28N6OPurezza:98%Colore e forma:SolidPeso molecolare:452.55C-Reactive Protein (CRP) (174-185)
CAS:CRP protein and its fragment (174-185, RS-83277) boost human monocyte and macrophage cancer-killing effects in vitro.Formula:C62H93N13O16Purezza:98%Colore e forma:SolidPeso molecolare:1276.48Poly(I:C):Kanamycin (1:1) sodium
Poly(I:C):Kanamycin (1:1) sodium is a complex.Poly(I:C) is a TLR3 and RIG-I/MDA5 agonist.Kanamycin is an antimicrobial,Gram-negative and positive bacteria.
Purezza:99%Colore e forma:SolidDCZ3301
CAS:DCZ3301 is a novel aryl-guanidino inhibitor.Formula:C20H16ClF3N6O2Purezza:99.89%Colore e forma:SolidPeso molecolare:464.83Ref: TM-T9658
1mg73,00€5mg149,00€10mg213,00€25mg319,00€50mg450,00€100mg605,00€200mg802,00€1mL*10mM (DMSO)166,00€RD-23
CAS:RD-23 is an orally active and selective RET PROTAC degrader. It facilitates the ubiquitination and degradation of the RETG810C mutant with a DC50 value of 11.7 nM. Additionally, RD-23 inhibits the activation of downstream Shc signaling and induces apoptosis (Apoptosis). It is useful for studying RET-related cancers.Formula:C52H56N12O4Colore e forma:SolidPeso molecolare:913.079FeTPPS
CAS:FeTPPS, a decomposition catalyst for 5,10,15,20-tetrakis(4-sulfonatophenyl) porphyrin iron(III) chloride peroxynitrite, neuroprotective.Formula:C44H28ClFeN4O12S4Colore e forma:SolidPeso molecolare:1024.27RET ligand-1
CAS:RETligand-1 is a target protein ligand that specifically interacts with RET and can be utilized in the synthesis of the PROTAC LDD39.Formula:C28H24F2N6O3Colore e forma:SolidPeso molecolare:530.525Z-WEHD-FMK
CAS:Z-WEHD-FMK is a cell-permeable and irreversible inhibitor of caspase-1/5. It also shows a robust inhibitory effect on cathepsin B activity (IC50: 6 μM).Formula:C37H42FN7O10Purezza:98%Colore e forma:SolidPeso molecolare:763.78ADPM06
CAS:ADPM06: nonporphyrin PDT agent; leads in apoptosis, strong IC50 in µM against human tumors.Formula:C34H24BBr2F2N3O2Colore e forma:SolidPeso molecolare:715.19Diazepinomicin
CAS:Diazepinomicin, from Micromonospora, blocks EGF-Ras-ERK pathway and induces apoptosis; an anti-tumor agent for K-Ras mutants.Formula:C28H34N2O4Purezza:98%Colore e forma:SolidPeso molecolare:462.58PROTAC RIPK degrader-2
CAS:PROTAC RIPK degrader-2 is a nonpeptidic PROTAC ,and potently targets serine-threonine kinase RIPK2 and has highly selective for RIPK2 degradation.Formula:C52H65N7O11S3Purezza:98%Colore e forma:SolidPeso molecolare:1060.31Psalmotoxin 1
CAS:Psalmotoxin 1 is a potent and selective acid-sensing ion channel 1a (ASIC1a) blocker.Formula:C200H312N62O57S6Purezza:98%Colore e forma:SolidPeso molecolare:4689.41SP3N hydrochloride
SP3N hydrochloride is a specific degrader of the prolyl isomerase (FKBP12). Its alkylamine moiety is metabolized into an active aldehyde (SP3CHO), which recruits the SCFFBXO22 ligase for the degradation of FKBP12. SP3N hydrochloride is applicable in cancer research.Colore e forma:Odour SolidSuramin
CAS:Suramin is an RdRp and PTPase inhibitor with anti-parasitic, anti-tumor, and anti-angiogenic activities, inhibiting sirtuins and DNA topoisomerase II.Formula:C51H40N6O23S6Purezza:99.80%Colore e forma:SolidPeso molecolare:1297.28Shepherdin (79-87)
CAS:Shepherdin 79-87: Amino acid fragment 79-87 of Hsp90/Survivin antagonist with anticancer properties.Formula:C41H64N12O12SPurezza:98%Colore e forma:SolidPeso molecolare:949.09MSU-42011
CAS:MSU-42011: oral RXR-like agonist, inhibits iNOS & p-ERK, antitumor in lung cancer model, effective preclinical treatment.Formula:C24H34N2O2Purezza:99.6%Colore e forma:SoildPeso molecolare:382.54p38-α MAPK-IN-8
p38-α MAPK-IN-8 (Compound 13) is a lipophilic cationic derivative. It exhibits cytotoxicity toward various tumor cells, inducing cell cycle arrest and apoptosis, as well as increasing reactive oxygen species (ROS) production and causing mitochondrial membrane potential depolarization. Its antitumor activity may be related to the p38α MAPK pathway, making it a potential candidate for cancer research.Formula:C49H62BrO4PColore e forma:SolidPeso molecolare:825.892β-Apopicropodophyllin
CAS:β-Apopicropodophyllin, a natural product isolated from Hyptis wticillata, promotes apoptosis through mechanisms including microtubule disruption, DNA damage,Formula:C22H20O7Colore e forma:SolidPeso molecolare:396.39EGFR T790M/L858R-IN-2
EGFRT790M/L858R-IN-2: selective inhibitor, IC50: 3.5 nM (mutant), 1290 nM (WT); reduces p-EGFR/AKT/ERK1/2, triggers apoptosis, G1 arrest, anti-cancer.Formula:C28H28FN7OColore e forma:SolidPeso molecolare:497.57
