Sirtuina
Le sirtuine sono una famiglia di deacetilasi dipendenti dal NAD+ che svolgono un ruolo cruciale nella regolazione di processi cellulari come la riparazione del DNA, l'invecchiamento, il metabolismo e la resistenza allo stress. Le sirtuine influenzano la riparazione del DNA deacetilando le proteine coinvolte nelle vie di riparazione, modulandone così l'attività. Gli inibitori e gli attivatori delle sirtuine sono strumenti preziosi nella ricerca sull'invecchiamento, il cancro e le malattie metaboliche, dove la regolazione della riparazione del DNA e della longevità cellulare è di interesse. Presso CymitQuimica, offriamo una gamma di modulatori di sirtuine di alta qualità per supportare la tua ricerca sulla riparazione del DNA, l'invecchiamento cellulare e la regolazione metabolica.
Trovati 95 prodotti per "Sirtuina".
Filtra per
Percentuale di purezza
0
100
|
0
|
50
|
90
|
95
|
100
- Prezzo più basso
- Prezzo più alto
- Purezza più bassa
- Purezza più alta
- Consegna più veloce
Nicotinamide riboside
CAS:Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-Formula:C11H15N2O5Purezza:99.58% - 99.89%Colore e forma:White SolidPeso molecolare:255.25Resveratrol
CAS:Resveratrol (SRT 501) is a polyphenolic natural product, a plant antitoxin with antioxidant and chemopreventive activities.Formula:C14H12O3Purezza:99.82% - 99.96%Colore e forma:SolidPeso molecolare:228.2433MC3482
CAS:MC3482 is a specific inhibitor of sirtuin5 (SIRT5).Formula:C33H38N4O8Purezza:98.56% - 99.90%Colore e forma:Yellow SolidPeso molecolare:618.6768SIRT-IN-2
CAS:SIRT-IN-2 is a potent SIRT1/2/3 inhibitor(IC50s of 4, 1, 7 μM, respectively).Formula:C15H21N5O3S2Purezza:98.26%Colore e forma:SolidPeso molecolare:383.489SIRT3 activator 1
SIRT3 Activator 1 (Compound 5v) is a selective activator of SIRT3. It enhances the expression of SIRT3, leading to upregulation of SOD2 and OPA1. This activity effectively mitigates mitochondrial dysfunction, alleviates oxidative stress, and maintains the vitality of cardiac myocytes. SIRT3 Activator 1 is useful in the study of cardiovascular diseases.Formula:C32H41N2NaO5Colore e forma:SolidPeso molecolare:556.67WAY-323061
CAS:WAY-323061 is a SIRT2 inhibitor.Formula:C25H21N5O2SPurezza:99.33%Colore e forma:SolidPeso molecolare:455.532MIND4-19
CAS:MIND4-19 is an inhibitor of SIRT2 with antitumor activity.Formula:C22H19N3OSPurezza:99.99%Colore e forma:SolidPeso molecolare:373.471Benzamide, 3-methoxy-N-(3-thiazolo[5,4-b]pyridin-2-ylphenyl)
CAS:3-Methoxybenzamide derivative modulates sirtuins; may boost cell lifespan and treat diseases.Formula:C20H15N3O2SPurezza:99.32%Colore e forma:SolidPeso molecolare:361.417Sirt1/2-IN-4
Sirt1/2-IN-4 (compound PS3) is a potent triple inhibitor of SIRT1, SIRT2, and SIRT3, exhibiting IC50 values of 1.2 μM (SIRT1), 1.9 μM (SIRT2), and 18.6 μM (Formula:C21H20N4O3S2Purezza:98%Colore e forma:SolidPeso molecolare:440.54SIRT2-IN-16
SIRT2-IN-16 (compound 17) is a SIRT2 inhibitor targeted at prostate-specific membrane antigen (PSMA).Formula:C55H91N9O15SColore e forma:SolidPeso molecolare:1150.43SIRT1-IN-1
CAS:SIRT1-IN-1 is a selective inhibitor of SIRT1 with an IC50 of 205 nM.Cost-effective and quality-assured.Formula:C14H16N2OPurezza:99.58%Colore e forma:SolidPeso molecolare:228.2896SIRT2-IN-12
SIRT2-IN-12 (Compound 3) is a SIRT2 inhibitor with an IC50 value of 50 μM.Formula:C23H21Cl2NO3Colore e forma:SolidPeso molecolare:429.08985SIRT-IN-5
SIRT-IN-5, a selective inhibitor of SIRT3 with an IC50 of 2.88 μM, facilitates the differentiation of multiple myeloma cells. This differentiation is associated with increased expression of the differentiation antigens CD49e and human immunoglobulin light chains λ and κ.Colore e forma:Odour SolidEt-29
CAS:Et-29 is a selective inhibitor of SIRT5 inhibitor with a Ki of 40 nM.Formula:C34H46N6O6SPurezza:99.52%Colore e forma:White SolidPeso molecolare:666.831Sirtuin modulator 2
CAS:Sirtuin modulator 2 (N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methoxybenzamide) exhibits antidiabetic, anti-inflammatory and antitumor activities.Formula:C19H15N3O2SPurezza:99.67%Colore e forma:Yellow SolidPeso molecolare:349.406SIRT5 inhibitor 8
CAS:SIRT5 inhibitor 8 (compound 10) is a moderately selective and substrate-competitive SIRT5 inhibitor with IC50=5.38 μM, with potential anticancer effects.Formula:C22H25ClN8O2SPurezza:99.56%Colore e forma:SolidPeso molecolare:501Z26395438
CAS:Z26395438 is an inhibitor of Sirtuin-1 with IC50 of 1.6 μM.Formula:C17H15FN2OPurezza:99.54%Colore e forma:White SolidPeso molecolare:282.3122SIRT6 activator 3
SIRT6 activator3 (Compound 24) is a SIRT6 activator with an EC50 of 5 μM. It demonstrates histone deacetylation activity and is applicable in cancer research.SIRT5 inhibitor 9
CAS:SIRT5 inhibitor 9 (compound 14) is a moderately selective and substrate-competitive SIRT5 inhibitor with IC50=4.07 μM and has potential anticancer effects.Formula:C24H29ClN8O4SPurezza:98.68%Colore e forma:SolidPeso molecolare:561.06HD-800
CAS:HD-800 is a highly selective SIRT2 inhibitor; IC50 37 nM; increases tubulin acetylation; regulates mitosis; cancer and neuroprotection research tool.Formula:C15H15N3O2Peso molecolare:269.3
![Benzamide, 3-methoxy-N-(3-thiazolo[5,4-b]pyridin-2-ylphenyl)](https://static.cymitquimica.com/products/TM/thumb-webp/T60001.webp)
