Tirosinasi
La tirosinasi è un enzima coinvolto nella sintesi della melanina, il pigmento responsabile del colore della pelle, dei capelli e degli occhi. La tirosinasi catalizza l'ossidazione della tirosina in DOPA e successivamente in DOPAchinone, portando alla formazione della melanina. Gli inibitori della tirosinasi sono di interesse per il trattamento dei disturbi dell'iperpigmentazione e sono anche utilizzati nell'industria cosmetica per ridurre la pigmentazione della pelle. Presso CymitQuimica, offriamo una vasta gamma di inibitori della tirosinasi e reagenti di alta qualità per supportare la tua ricerca in dermatologia, enzimologia e scienza cosmetica.
Trovati 72 prodotti di "Tirosinasi"
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KW-2450 Formate
KW-2450 Formate is an IGF-1R/IR tyrosine kinase inhibitor with antitumor effects that acts through inhibition of Aurora A and B kinases.KW-2450 Formate inhibits the growth of TNBC xenografts and induces tetraploid accumulation.Formula:C29H31N5O5SPurezza:99.28%Colore e forma:SolidPeso molecolare:561.655-Feruloylquinic acid
CAS:5-Feruloylquinic acid, a potent Sirt1 activator, may aid in developing anti-aging drugs.Formula:C17H20O9Purezza:99.03%Colore e forma:SolidPeso molecolare:368.344-Chlorosalicylic acid
CAS:<p>4-Chlorosalicylic acid (4-Chloro-2-hydroxybenzoic acid, 4-chloro salicylic acid) is antimicrobial compositions comprising a metal salt and a benzoic acid analog</p>Formula:C7H5ClO3Purezza:98.59%Colore e forma:Off-White To Light Beige PowderPeso molecolare:172.57Flanvotumab
CAS:Flanvotumab (IMC-20D7S) is a humanized antibody targeting TYRP1 with strong antitumor effects via NK cells and ADCC.Purezza:> 95%Colore e forma:LiquidPeso molecolare:145.42 kDaArbutin
CAS:Arbutin, a bearberry extract, blocks melanin by inhibiting tyrosinase.Formula:C12H16O7Purezza:99.58% - 99.93%Colore e forma:Colorless Elongated Prisms From Moist Ethyl Acetate White PowderPeso molecolare:272.252,3-Dihydroisoginkgetin
CAS:2,3-Dihydroisoginkgetin is a Tyrosinase inhibitor with 36.84% inhibition at 0.1 mM.Formula:C32H24O10Purezza:98%Colore e forma:SolidPeso molecolare:568.53hTYR/AbTYR-IN-1
CAS:hTYR/AbTYR-IN-1 is a dual hTYR/AbTYR inhibitor with inhibitory effects on hTYR and AbTYR, with IC50s of 5.4 μM and 3.52 μM, respectively.Formula:C18H20N2O3Purezza:99.73%Colore e forma:SoildPeso molecolare:312.36Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2
CAS:Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effectFormula:C47H64N14O10Colore e forma:SolidPeso molecolare:985.1Tyrosinase-IN-34
Tyrosinase-IN-34 (compound 5a), a human tyrosinase inhibitor (IC 50: 3.5 μM), shows promise in regulating melanogenesis and pigmentation.Formula:C19H14BrClN4OColore e forma:SolidPeso molecolare:429.7Tyrosinase
CAS:<p>Tyrosinase (Polyphenol oxidase) is a key rate-limiting enzyme encoded by the TYR gene that controls melanin production and catalyzes tyrosine oxidation.</p>Colore e forma:Solid(Z)-SU14813
CAS:<p>(Z)-SU14813 is a tyrosine kinase inhibitor with anticardiogenic and antitumor activity.</p>Formula:C23H27FN4O4Purezza:98.18%Colore e forma:SolidPeso molecolare:442.48Tyrosinase-IN-13
Tyrosinase-IN-13 (compound 3c), stemming from Flurbiprofen, acts as a potent non-competitive inhibitor of tyrosinase, exhibiting IC50 and Ki values of 68 μM andFormula:C23H18ClFN4OSPurezza:98%Colore e forma:SolidPeso molecolare:452.93Swertiajaponin
CAS:Swertiajaponin possesses antimicrobial activity.Formula:C22H22O11Purezza:99.85%Colore e forma:SolidPeso molecolare:462.4Potassium iodide
CAS:Potassium iodide 用于治疗过度活跃的甲状腺，并保护甲状腺免受吞咽或吸入放射性碘的辐射影响。可在意外接触放射性碘后或服用含放射性碘的药物前后使用。Formula:IKColore e forma:White Solid CrystallinePeso molecolare:166.01Tyrosinase-IN-32
<p>Tyrosinase-IN-32 (compound 11), a hydroxamate-based alkaloid extracted from black pepper (Piper nigrum L.), functions as an inhibitor of mushroom tyrosinase. In addition to its inhibitory properties, it exhibits antioxidant activity.</p>Formula:C15H19NO3Colore e forma:SolidPeso molecolare:261.32[Asp371]-Tyrosinase (369-377), human
CAS:Tyrosinase (369-377,YMDGTMSQV) originates from tyrosinase and needs TAP and proteosome for cell presentation.Formula:C42H66N10O16S2Purezza:98%Colore e forma:SolidPeso molecolare:1031.16Tyrosinase-IN-15
Tyrosinase-IN-15 (Compound 39), with an IC50 of 7.12 μM and a Ki of 11.8 μM, functions as a tyrosinase inhibitor [1].Purezza:98%Colore e forma:Odour SolidTyrosinase-IN-26
Tyrosinase-IN-26 (compound 13) is a non-competitive inhibitor of tyrosinase, with an IC50 value of 68.86 µM. It is capable of inhibiting melanin production.Formula:C25H24N2O6Peso molecolare:448.16344Tyrosinase-IN-14
<p>Tyrosinase-IN-14 (compound 7m), a tyrosinase inhibitor, modulates the enzyme's secondary structure to diminish its catalytic function, exhibits low cytotoxicity</p>Formula:C21H13Br2N3O3SPurezza:98%Colore e forma:SolidPeso molecolare:547.22Tyrosinase-IN-40
Tyrosinase-IN-40 (Compound 9r) is a competitive inhibitor of tyrosinase, boasting an IC50 value of 17.02 µM and a Ki value of 14.87 µM. This compound also exhibits antioxidant activity and can be utilized in studies related to melanin.Formula:C34H29N9O10Colore e forma:SolidPeso molecolare:723.648Tyrosinase-IN-21
Tyrosinase-IN-21 (compound 3g) is a tyrosinase inhibitor with an IC50 value of 80.93 μM.Formula:C23H20N4O3S2Peso molecolare:464.09768Diaminopropionoyl tripeptide-33
CAS:Diaminopropionoyl Tripeptide-33 is a bioactive peptide that safeguards skin cells against UVA-induced DNA damage and is utilized as a cosmetic ingredient [1].Formula:C17H27N7O6Purezza:98%Colore e forma:SolidPeso molecolare:425.44Tyrosinase-IN-19
Tyrosinase-IN-19 (compound 9), a competitive tyrosinase inhibitor, exhibits potent antioxidant activities by neutralizing ROS, ABTS+, and DPPH radicals andPurezza:98%Colore e forma:Odour SolidTyrosinase-IN-36
<p>Tyrosinase-IN-36 is a moderately potent inhibitor of tyrosine, exhibiting an inhibition percentage of 42.75% compared to kojic acid at a concentration of 100 μM and possesses antioxidant activity.</p>Colore e forma:Odour SolidTyrosinase-IN-38
Tyrosinase-IN-38 (compound 6b) is a competitive inhibitor of tyrosinase, demonstrating an IC50 of 25.82 μM and exhibits antioxidant activity.Colore e forma:Odour SolidAnti-Tyrosinase/TYR Antibody (7Z445)
Anti-Tyrosinase/TYR Antibody (7Z445) is an antibody targeting Tyrosinase/TYR. Anti-Tyrosinase/TYR Antibody (7Z445) can be used in ELISA, IF.Colore e forma:Odour LiquidIsoastilbin
CAS:Isoastilbin is a dihydroflavonol glycoside compound in Rhizoma Smilacis glabrae and Astragalus membranaceus.Formula:C21H22O11Purezza:99.54% - 99.95%Colore e forma:SolidPeso molecolare:450.39Methyl rosmarinate
CAS:<p>Methyl rosmarinate, from Rabdosia serra, inhibits tyrosinase (IC50: 0.28 mM), α-glucosidase, MMP-1, and has antioxidant, antifungal properties.</p>Formula:C19H18O8Purezza:98.68% - 99.62%Colore e forma:SolidPeso molecolare:374.34Deoxyarbutin
CAS:<p>DeoxyArbutin(IC50=50 nM) inhibits tyrosinase activity reversibly.</p>Formula:C11H14O3Purezza:99.04% - 99.88%Colore e forma:SolidPeso molecolare:194.23Trifolirhizin
CAS:<p>Trifolirhizin exerts varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis, and therefore, are candidates as skin-whitening agents.</p>Formula:C22H22O10Purezza:98% - 99.67%Colore e forma:SolidPeso molecolare:446.4Oxyresveratrol
CAS:1.Formula:C14H12O4Purezza:98.09% - 99.69%Colore e forma:Yellow SolidPeso molecolare:244.24BENZYLACETONE
CAS:Benzylacetone (4-Phenyl-2-butanone) is an aromatic compound extracted from incense wood. Benzylacetone has appetite-enhancing and exercise-reducing properties.Formula:C10H12OPurezza:98.79%Colore e forma:Colourless LiquidPeso molecolare:148.23-(2,4-Dihydroxyphenyl)propanoic acid
CAS:3-(2,4-Dihydroxyphenyl)propanoic acid (Hydroumbellic acid) is a metabolite that is produced by the metabolism of 3-(2, 4-dihydroxyphenyl)prop-2-enoic acid.Formula:C9H10O4Purezza:98.12%Colore e forma:SolidPeso molecolare:182.173,4-Dimethoxyphenol
CAS:3,4-Dimethoxyphenol (4-Hydroxyveratrole) is an active biochemical.Formula:C8H10O3Purezza:98.57%Colore e forma:Red Crystal PowderPeso molecolare:154.16Gnetol
CAS:Gnetol inhibits butyrylcholinesterase (IC50: 1.3 μM), tyrosinase, melanin synthesis in B16 cells, and AA-induced platelet aggregation.Formula:C14H12O4Purezza:98.55% - ≥95%Colore e forma:SolidPeso molecolare:244.24Glycolic acid
CAS:Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation,and used in skincare productsFormula:C2H4O3Purezza:97.36%Colore e forma:Colourless Solid CrystallinePeso molecolare:76.05Tropolone
CAS:Tropolone, a metal chelator, possesses weak antioxidative and radical-scavenging properties and shows a strong affinity for ferric ionFormula:C7H6O2Purezza:99.89%Colore e forma:Light Yellow-Cream SolidPeso molecolare:122.123',4'-Dihydroxyacetophenone
CAS:3',4'-Dihydroxyacetophenone (Qingxintong) is an active constituent of Chinese medicine.Formula:C8H8O3Purezza:99.63% - 99.85%Colore e forma:Light Yellow To Dark Yellow LiquidPeso molecolare:152.153-O-Ethyl-L-ascorbic acid
CAS:3-O-Ethyl-L-ascorbic acid is a cosmetic tyrosinase inhibitor with whitening ability and is a stabilized vitamin C derivative.Formula:C8H12O6Purezza:97.35% - 99.99%Colore e forma:White To Very Pale Yellow Crystalline Powder Solid PowderPeso molecolare:204.18D-Tyrosine
CAS:D-Tyrosine inhibits melanin production and biofilm formation, promoting biofilm dispersal without hindering bacterial growth.Formula:C9H11NO3Purezza:99.86%Colore e forma:White CrystalsPeso molecolare:181.19α-Arbutin
CAS:<p>α-Arbutin (4-hydroxyphenyl-D-lucopyranoside) is a synthetic and functional active ingredient for skin lightening.</p>Formula:C12H16O7Purezza:99.82%Colore e forma:Solid PowderPeso molecolare:272.252-Ketoglutaric acid Sodium
CAS:2-Ketoglutaric acid Sodium (AKG) is a key molecule in the TCA cycle.Formula:C5H5NaO5Purezza:97.77%Colore e forma:SolidPeso molecolare:168.084-Butylresorcinol
CAS:4-Butylresorcinol (Butylresorcinol) is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.Formula:C10H14O2Purezza:99.48% - ≥95%Colore e forma:Light Beige Solid PowderPeso molecolare:166.22β-Tocopherol
CAS:Beta-Tocopherol has effects on human erythroleukemia cell (HEL) adhesion induced by phorbol 12-myristate 13-acetate (PMA).Cost-effective and quality-assured.Formula:C28H48O2Purezza:99.8% - 99.92%Colore e forma:SolidPeso molecolare:416.682-Hydroxy-4-methoxybenzaldehyde
CAS:<p>2-Hydroxy-4-methoxybenzaldehyde (4-Methoxysalicylaldehyde) is an isomer of Vanillin, and a potent tyrosinase inhibitor, could be used to synthesis Urolithin M7.</p>Formula:C8H8O3Purezza:99.78%Colore e forma:Colorless Needle-Like CrystalPeso molecolare:152.15SU 4942
CAS:<p>SU-4942 is a modulator of tyrosine kinase signaling.</p>Formula:C15H10BrNOPurezza:99% - 99.32%Colore e forma:SolidPeso molecolare:300.15SU5214
CAS:SU5214 is a modulator of tyrosine kinase signal transduction.Formula:C16H13NO2Purezza:99.45% - 99.55%Colore e forma:SolidPeso molecolare:251.28lavendustin B
CAS:Lavendustin B inhibits Tyrosine Kinase and HIV-1 integrase-LEDGF/p75 interaction.Formula:C21H19NO5Purezza:95.72%Colore e forma:Off-White SolidPeso molecolare:365.38Benzoyloxypaeoniflorin
CAS:Benzoyloxypaeoniflorin, a natural compound, enhances blood flow by inhibiting platelet aggregation and coagulation.Formula:C30H32O13Purezza:98.52% - 99.96%Colore e forma:SolidPeso molecolare:600.57Mirificin
CAS:<p>Mirificin (BCP10902) is an active ingredient in Tongmai formula (TMF) which is a well-known Chinese medicinal preparation. Anti-oxidant.</p>Formula:C26H28O13Purezza:99.33% - 99.80%Colore e forma:SolidPeso molecolare:548.49Taxifolin
CAS:Taxifolin (Dihydroquercetin) is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.Formula:C15H12O7Purezza:94.91% - 98.9%Colore e forma:Yellowish PowderPeso molecolare:304.25XMD16-5
CAS:XMD16-5 blocks TNK2, linked to advanced lung/prostate cancers and breast cancer metastasis in mice; disrupts signaling in several tumors.Formula:C23H24N6O2Purezza:98.89% - 99.98%Colore e forma:SolidPeso molecolare:416.48XMD8-87
CAS:XMD8-87 (ACK1-B19), a TNK2 inhibitor, strongly blocks TNK2 phosphorylation and mutations in tumors.Formula:C24H27N7O2Purezza:98.05% - 99.89%Colore e forma:SolidPeso molecolare:445.522-Methoxycinnamic acid
CAS:1. 2-Methoxycinnamic acid (o-Methoxycinnamic acid) can enhance inhibition of tyrosinase activity.Formula:C10H10O3Purezza:99.68%Colore e forma:Light Yellow Crystalline PowderPeso molecolare:178.18ZAP-180013
CAS:<p>ZAP-180013 is an inhibitor of zeta-chain-associated protein kinase 70 (ZAP70,IC50 : 1.8 μM).</p>Formula:C19H17Cl2N3O4SPurezza:98.89%Colore e forma:SolidPeso molecolare:454.33Methyl cinnamate
CAS:<p>Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects.</p>Formula:C10H10O2Purezza:99.88%Colore e forma:Colorless To Pale Yellow Solid CrystallinePeso molecolare:162.192-Ketoglutaric acid
CAS:2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM). 2-Ketoglutaric acid is an intermediate of the Krebs cycle. High-Quality, Low-Cost!Formula:C5H6O5Purezza:99.28%Colore e forma:SolidPeso molecolare:146.1Mulberroside A
CAS:1.Formula:C26H32O14Purezza:99.05% - 99.4%Colore e forma:SolidPeso molecolare:568.52(R)-Trolox
CAS:(R)-Trolox is a selective tyrosinase inhibitor used in food, cosmetics, and pharmaceutical products.Formula:C14H18O4Purezza:99.88%Colore e forma:SolidPeso molecolare:250.29Tyrosinase
CAS:<p>Copper-containing enzyme that catalyzes the first step in the synthesis of melanin</p>Colore e forma:PowderTyrosinase
CAS:<p>Tyrosinase (EC 1.14.18.1) is an enzyme that oxydises phenol derivatives (e.g. tyrosine, dopamine). One unit of tyrosinase dissolved in 3mL reaction mixture will cause the absorbance at 280nm to increase by 0.001 in the presence of L-tyrosine at pH 6.5 and 25 °C. L-tyrosine is available here.Lyophilized, from mushroom. Activity ≥1000 unit/mg</p>Colore e forma:Powder3,4-Dihydroxybenzylamine hydrobromide
CAS:<p>3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase and melanoma growth, varying with tyrosinase activity.</p>Formula:C7H10BrNO2Purezza:98.49%Colore e forma:Light Beige Crystalline PowderPeso molecolare:220.06Tyrosinase-IN-7
CAS:Tyrosinase-IN-7 is a small-molecule tyrosinase inhibitor (IC50 1.57 μM) that suppresses melanin activity and cell growth with low cytotoxicity.Formula:C15H10O5Purezza:99%Colore e forma:SolidPeso molecolare:270.24Tyrosinase-IN-2
CAS:Tyrosinase-IN-2, a potent tyrosinase inhibitor, may help in skin lightening and food preservation research.Formula:C8H8N4O2SPurezza:99.78%Colore e forma:SolidPeso molecolare:224.24Plodicitinib
CAS:Plodicitinib is an inhibitor of Janus tyrosine kinase 3/TEC family kinase, exhibiting anti-inflammatory properties.Formula:C19H22FN7O2Colore e forma:SolidPeso molecolare:399.422Isobutylamido thiazolyl resorcinol
CAS:Isobutylamido thiazolyl resorcinol is a tyrosinase (Tyrosinase) inhibitor that prevents pigment deposition induced by ultraviolet radiation.Formula:C13H14N2O3SColore e forma:SolidPeso molecolare:278.33Tyrosinase-IN-39
<p>Tyrosinase-IN-39 (compound 5r) is a competitive inhibitor of tyrosinase, with an IC50 of 6.4 μM, and is used in the study of skin diseases.</p>Formula:C23H19N5O4S2Colore e forma:SolidPeso molecolare:493.56Tyrosinase-IN-37
CAS:<p>Tyrosinase-IN-37 (Compound 3c) is a potent inhibitor of tyrosinase, with an IC50 value of 1.02 μM, which is 14 times more effective than kojic acid (IC50 of 14.74 μM). This compound effectively prevents the browning of Rosa roxburghii and can also inhibit browning not caused by tyrosinase.</p>Formula:C12H12N6SColore e forma:SolidPeso molecolare:272.33Tyrosinase-IN-35
CAS:Tyrosinase-IN-35 (compound 6g), exhibiting a IC 50 value of 2.09 μM, serves as a more effective inhibitor of human tyrosinase compared to Kojic Acid (IC 50: 16.38 μM). At concentrations of 4 μM and 8 μM, this compound effectively lowers melanin levels in melanoma B16F10 cells in vitro.Formula:C17H15N5OSColore e forma:SolidPeso molecolare:337.40Tyrosinase-IN-33
CAS:<p>Tyrosinase-IN-33 (compound 5), a pyridine-based compound, acts as an effective inhibitor of diphenolase activity in mushroom tyrosinase. It significantly reduces enzyme activity with an IC50 of 9.0 μM.</p>Formula:C19H17NS2Colore e forma:SolidPeso molecolare:323.48Tyrosinase-IN-20
CAS:<p>Tyrosinase-IN-20 (compound 6a) acts as a potent Tyrosinase inhibitor, demonstrating an IC 50 value of 28.50 μM [1].</p>Formula:C17H18N2O2SColore e forma:SolidPeso molecolare:314.4Tyrosinase-IN-29
CAS:Tyrosinase-IN-29 (compound 5c) is an effective inhibitor of abTYR tyrosinase, demonstrating an IC50 value of 6.11 μM. It is suitable for further research into the inhibition of excessive skin pigmentation.Formula:C10H9NO2Colore e forma:SolidPeso molecolare:175.18
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