Aminopeptidasi
Le aminopeptidasi sono un gruppo di enzimi che catalizzano la scissione degli amminoacidi dall'estremità N-terminale di peptidi e proteine, svolgendo un ruolo cruciale nella maturazione e degradazione delle proteine. Questi enzimi sono coinvolti in vari processi fisiologici, tra cui la presentazione degli antigeni, la regolazione degli ormoni peptidici e l'omeostasi cellulare. Gli inibitori delle aminopeptidasi sono di interesse per il trattamento di malattie come il cancro, l'infiammazione e le malattie infettive. Presso CymitQuimica, offriamo una varietà di inibitori delle aminopeptidasi per supportare la tua ricerca in proteomica, sviluppo di farmaci e trattamento delle malattie.
Trovati 75 prodotti di "Aminopeptidasi"
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ERAP1-IN-1
CAS:ERAP1-IN-1 inhibits and allosterically activates ERAP1, affecting fluorogenic, chromogenic, and nonamer peptide substrates.Formula:C20H21F3N2O5SPurezza:98.95%Colore e forma:SolidPeso molecolare:458.45Bufexamac
CAS:Bufexamac (Bufexamic acid) is a COX inhibitor for IFN-α release with anti-inflammatory, analgesic, and antipyretic action.Formula:C12H17NO3Purezza:99.73%Colore e forma:Acicular CrystalPeso molecolare:223.27Probestin
CAS:Probestin is an aminopeptidase M inhibitor, isolated from Streptomyces azureus MH663-2F6.Formula:C26H38N4O6Purezza:98%Colore e forma:SolidPeso molecolare:502.60Aminopeptidase N inhibitor 2
<p>AminopeptidaseN inhibitor 2 is an APN inhibitor (IC50: 4.3 μM) with antitumor properties.</p>Formula:C12H16F2N2O4SColore e forma:SolidPeso molecolare:322.07988BAY-277
<p>BAY-277 is a degrader of METAP2, with IC50 values of 5.8 nM for human METAP2 (hMETAP2) and 5.9 nM for mouse METAP2 (mMETAP2).</p>Formula:C44H52N8O5Colore e forma:SolidPeso molecolare:772.93LTA4H-IN-4
<p>LTA4H-IN-4 (compound 3) is an orally active inhibitor of LTA4H. It exhibits an IC50 value of 156 μM against hERG and is applicable for inflammation-related research.</p>Leuhistin
CAS:Leuhistin is an aminopeptidases N inhibitor isolated from Bacillus laterosporus BMI156-14F1.Formula:C11H19N3O3Purezza:98%Colore e forma:White To Off-White SolidPeso molecolare:241.29Matlystatin A
CAS:Matlystatin A is an inhibitor of aminopeptidase. It shows multiple inhibitory activities against both aminopeptidase N and matrix metalloproteinases.Formula:C27H47N5O8SColore e forma:SolidPeso molecolare:601.76SDUY817
<p>SDUY817 is a dual APN/NEP inhibitor with IC50 values of 0.29 μM for APN and 7.4 μM for NEP. It exhibits analgesic effects in a concentration- and time-dependent manner, making it a potential candidate for research in the field of neuropathic pain disorders.</p>Formula:C18H16IN3O3Colore e forma:SolidPeso molecolare:449.24CD13-IN-1
<p>CD13-IN-1 (Compound 5f) is a CD13 inhibitor with an IC50 value of 1.71 μM. It effectively suppresses the proliferation of various tumor cells, demonstrating antitumor activity.</p>Colore e forma:Odour SolidAmastatin hydrochloride
CAS:Amastatin HCl is an inhibitor of aminopeptidase. It also induces vasoconstriction.Formula:C21H39ClN4O8Colore e forma:White To Off-White PowderPeso molecolare:511.01ecMetAP-IN-1
CAS:ecMetAP-IN-1 可用作 QSAR 模型，以使用多元线性回归研究蛋氨酸氨基肽酶抑制剂作为抗癌剂。Formula:C13H11N3Purezza:99.34%Colore e forma:SolidPeso molecolare:209.25NGR peptide
CAS:Cell-penetrating peptideFormula:C20H36N10O8S2Purezza:98%Colore e forma:SolidPeso molecolare:608.69JNJ-40929837 succinate
CAS:JNJ-40929837 succinate is a selective, orally active inhibitor of LTA 4 H (leukotriene A 4 hydrolase). This compound effectively inhibits aminopeptidase activity, leading to the accumulation of Pro-Gly-Pro in serum, and can be utilized in asthma research [1].Formula:C22H24N4O2S·xC4H6O4Colore e forma:SolidBDM_92499
BDM_92499 is a nanomolar, selective IRAP inhibitor with an IC50 of 3.4 nM. It also inhibits ERAP1 and ERAP2, with IC50 values of 0.46 μM and 4.2 μM, respectively.Colore e forma:Odour SolidAclimostat
CAS:<p>Aclimostat (ZGN-1061) is a MetAP2 inhibitor with strong preclinical results, improving obesity-related metrics and gene expression.</p>Formula:C26H42N2O6Colore e forma:SolidPeso molecolare:478.63Relzomostat
CAS:Relzomostat inhibits MetAP2, with research potential for obesity and type 2 diabetes.Formula:C24H36F2N2O5Colore e forma:SolidPeso molecolare:470.558SDUY816
<p>SDUY816 is an orally active dual APN/NEP inhibitor, with IC50 values of 0.68 μM for APN and 6.9 μM for NEP. It exhibits analgesic properties and demonstrates good safety and pharmacokinetic profiles, having an oral bioavailability of 27% and a half-life of 4.02 hours in rats (oral, 10 mg/kg). SDUY816 is applicable for research in the field of neuropathic pain disorders.</p>Formula:C18H16IN3O3Colore e forma:SolidPeso molecolare:449.24ERAP1-IN-3
ERAP1-IN-3 (compound 13) is a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1), with a pIC50 value of 8.6. ERAP1-IN-3 shows potential for research in cancer immunotherapy and autoimmune disease studies.Formula:C22H22N2O4SColore e forma:SolidPeso molecolare:410.49Antho-rwamide I
CAS:Antho-rwamide I is an anthozoan neuropeptide.Formula:C31H46N10O7Colore e forma:SolidPeso molecolare:670.76
