Proteasi/Proteasoma
Gli inibitori delle proteasi e del proteasoma sono composti che bloccano l'attività delle proteasi e del proteasoma, che sono coinvolti nella degradazione e nel turnover delle proteine. Questi inibitori sono fondamentali per studiare la regolazione dell'omeostasi proteica, il controllo del ciclo cellulare e l'apoptosi. Gli inibitori delle proteasi e del proteasoma vengono anche utilizzati nel trattamento di malattie come il cancro, dove la degradazione anomala delle proteine svolge un ruolo nella progressione della malattia. Inibendo le proteasi o il proteasoma, questi composti possono indurre la morte cellulare nelle cellule tumorali e sono strumenti critici sia per la ricerca di base che per lo sviluppo terapeutico. Presso CymitQuimica, offriamo una vasta gamma di inibitori delle proteasi e del proteasoma di alta qualità per supportare la tua ricerca in biochimica, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Proteasi/Proteasoma"
- Acetil-CoA carbossilasi(36 prodotti)
- Cisteina proteasi(110 prodotti)
- DPP-4(21 prodotti)
- Glutaminasi(45 prodotti)
- Proteasi HIV(508 prodotti)
- PAI-1(26 prodotti)
- Inibitori della proteasi(50 prodotti)
- Ricettore attivato dalla proteasi(54 prodotti)
- Proteasoma(95 prodotti)
- Proteasi serina(55 prodotti)
- p97(15 prodotti)
Mostrare 3 più sottocategorie
Trovati 1082 prodotti di "Proteasi/Proteasoma"
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Isobutylamido thiazolyl resorcinol
CAS:Isobutylamido thiazolyl resorcinol is a tyrosinase (Tyrosinase) inhibitor that prevents pigment deposition induced by ultraviolet radiation.Formula:C13H14N2O3SColore e forma:SolidPeso molecolare:278.33Tyrosinase-IN-37
CAS:Tyrosinase-IN-37 (Compound 3c) is a potent inhibitor of tyrosinase, with an IC50 value of 1.02 μM, which is 14 times more effective than kojic acid (IC50 of 14.74 μM). This compound effectively prevents the browning of Rosa roxburghii and can also inhibit browning not caused by tyrosinase.Formula:C12H12N6SColore e forma:SolidPeso molecolare:272.333-Aminobenzene-1,2-diol
CAS:3-Aminobenzene-1,2-diol (compound C8) is an inhibitor of matrix metalloproteinases (MMP), with IC50 values of 20, 26, 16, and 16.3 μM against MMP-2, MMP-8, MMP-9, and MMP-14, respectively.Formula:C6H7NO2Colore e forma:SolidPeso molecolare:125.13GB111-NH2
CAS:GB111-NH2, a cysteine cathepsin inhibitor, is applicable in cancer research [1].Formula:C33H39N3O6Colore e forma:SolidPeso molecolare:573.68Matriptase-IN-2 free base
CAS:Matriptase-IN-2 free base, a matriptase inhibitor with a K i of 5 nM, has potential applications in musculoskeletal system disorder research (WO2011023958A1; compound 432) [1].Formula:C29H33Cl2N5O3SColore e forma:SolidPeso molecolare:602.58ABT-072
CAS:ABT-072 is a nonnucleoside NS5B polymerase inhibitor and a candidate drug evaluated for treatment of hepatitis C virus.Formula:C24H27N3O5SPurezza:98%Colore e forma:SolidPeso molecolare:469.55UK 356618
CAS:<p>UK 356618 is a potent and selective inhibitor of matrix metalloprotease-3 (IC50: 5.9 nM).</p>Formula:C34H43N3O4Purezza:98%Colore e forma:SolidPeso molecolare:557.72Cyclophilin inhibitor 1
CAS:Cyclophilin inhibitor 1: orally available, Kd 5 nM, potent against HCV, EC50 for HCV 2a is 98 nM.Formula:C31H39N5O7Purezza:98%Colore e forma:SolidPeso molecolare:593.67CatD-IN-1
CAS:CatD-IN-1 (Compound 5) is a Cathepsin D inhibitor with an IC50 of 0.44 μM, and it shows potential for research in the field of osteoarthritis.Formula:C18H18Cl2N4O5Colore e forma:SolidPeso molecolare:441.265Marizomib
CAS:Marizomib is a novel irreversible brain-permeable proteasome inhibitor that inhibits CT-L, CT-T-laspase-like, and trypsin-like 20S proteasomes.Cost-effective and quality-assured.Formula:C15H20ClNO4Purezza:98.03% - 99.41%Colore e forma:SolidPeso molecolare:313.78Tyrosinase-IN-20
CAS:<p>Tyrosinase-IN-20 (compound 6a) acts as a potent Tyrosinase inhibitor, demonstrating an IC 50 value of 28.50 μM [1].</p>Formula:C17H18N2O2SColore e forma:SolidPeso molecolare:314.4Tyrosinase-IN-29
CAS:Tyrosinase-IN-29 (compound 5c) is an effective inhibitor of abTYR tyrosinase, demonstrating an IC50 value of 6.11 μM. It is suitable for further research into the inhibition of excessive skin pigmentation.Formula:C10H9NO2Colore e forma:SolidPeso molecolare:175.18BMT-052
CAS:BMT-052 is a potent and selective Pan-genotypic HCV NS5B Polymerase Inhibitor (EC50 = 7 nM).Formula:C30H17D9F4N6O5Purezza:98%Colore e forma:SolidPeso molecolare:635.61SSR-182289A (Free)
CAS:SSR-182289A (Free) is a thrombin inhibitor.Formula:C30H33F2N5O4SPurezza:98%Colore e forma:SolidPeso molecolare:597.68SAR107375
CAS:SAR107375 is a potent, orally active dual inhibitor of thrombin and factor Xa, with K_i values of 1 nM and 8 nM for factor Xa and thrombin, respectively [1].Formula:C24H30ClN5O5S2Colore e forma:SolidPeso molecolare:568.11HCV-IN-40
CAS:HCV-IN-39 is a potent oral drug inhibiting HCV, effective on GT1a (EC50: 0.259μM), GT1b (EC50: 0.434μM), GT1b CES1 (EC50: 0.069μM) replicons.Formula:C21H26BrFN3O9PColore e forma:SolidPeso molecolare:594.32Valopicitabine
CAS:<p>Valopicitabine is an effective prodrug of the effective anti-HCV drug 2'-C-methylcytidine and can be used as a promising antiviral drug for the study of chronic</p>Formula:C15H24N4O6Purezza:98%Colore e forma:SolidPeso molecolare:356.37SBI-581
SBI-581: oral, potent TAO3 inhibitor, IC50=42nM, alters TKS5α at RAB11+ vesicles, blocks invadopodia, good mouse pharmacokinetics, anti-tumor.Formula:C24H21N3O2Colore e forma:SolidPeso molecolare:383.44Plasma kallikrein-IN-2
Plasma kallikrein-IN-2: PKal inhibitor, IC50=0.1 nM. Used in angioedema, diabetic eye disease research.Formula:C28H24ClF3N8O3Colore e forma:SolidPeso molecolare:612.99Beclabuvir
CAS:Beclabuvir blocks HCV NS5B polymerase at thumb site 1, effective on genotypes 1, 3, 4, 5 with IC50 <28 nM.Formula:C36H45N5O5SPurezza:99.87% - 99.93%Colore e forma:SolidPeso molecolare:659.84TMPRSS6-IN-1 TFA
TMPRSS6-IN-1 (TFA) is a potent inhibitor of TMPRSS6 (Matriptase-2), a member of the TTSP family (a type of transmembrane serine protease). TMPRSS6 is a type II TTSP, and genetically reduced levels of TMPRSS6 have been shown to improve symptoms of hemochromatosis and β-thalassemia in mice.Formula:C35H41F3N8O6S2Colore e forma:SolidPeso molecolare:790.875TG-2-IN-4
CAS:TG-2-IN-4 (compound 8), an inhibitor of transglutaminase 2 (TG2) with an IC 50 value of less than 0.5 mM, is utilized in the study of inflammatory disorders [1].Formula:C34H40N6O5Colore e forma:SolidPeso molecolare:612.72DPP-4-IN-15
CAS:DPP-4-IN-15 (Compound 22) is a non-competitive inhibitor of dipeptidyl peptidase-4 (DPP-4) with an IC50 value of 8.24 μM.Formula:C17H14F3N3O2SColore e forma:SolidPeso molecolare:381.372BI 224436
CAS:BI 224436 is an inhibitor of HIV-1 noncatalytic site integrase. With EC50 values of less than 15 nM against different HIV-1 laboratory strains.Formula:C27H26N2O4Colore e forma:SolidPeso molecolare:442.51BI-1915
CAS:<p>BI-1915 is a selective inhibitor of Cathepsin S, with an IC50 of 17 nM. It is utilized in the research of autoimmune diseases.</p>Formula:C21H37N5O3Colore e forma:SolidPeso molecolare:407.55HCV NS5B polymerase-IN-2
CAS:HCVNS5B polymerase-IN-2 (Compound 298) is an inhibitor of the Ns5b polymerase. It holds potential for research into the treatment of hepatitis C virus (HCV) infections.Formula:C26H24N2O4Colore e forma:SolidPeso molecolare:428.48SMCypI C31
SMCypIC31, a non-peptide cyclophilin inhibitor, blocks PPIase at 0.1 μM IC50 and fights various HCV genotypes (EC50: 1.20-7.76 μM).Formula:C27H30N4O2SColore e forma:SolidPeso molecolare:474.62Cathepsin C-IN-3
Cathepsin C-IN-3 is a potent inhibitor of histone C (IC50: 61.79 nM) and also inhibits THP-1 cells (IC50: 101.5 nM) and U937 cells (IC50: 86.5 nM).Formula:C28H21F3N6OSColore e forma:SolidPeso molecolare:546.57CM-352
CAS:CM-352 is a metalloproteinase inhibitor that reduces brain damage and improves functional recovery in rat models of cerebral hemorrhage.Formula:C24H29N3O6SPurezza:97.24%Colore e forma:SolidPeso molecolare:487.57Anti-infective agent 10
CAS:Anti-infective agent 10 (Compound Example 30) is an ns5b polymerase inhibitor that functions as an anti-HCV agent.Formula:C26H25N3O7SColore e forma:SolidPeso molecolare:523.56Cathepsin C-IN-4
Cathepsin C-IN-4 is a potent inhibitor (IC50: 65.6 nM) of histone C. Cathepsin C-IN-4 inhibits THP-1 cells (IC50: 203.4 nM) and U937 cells (IC50: 177.6 nM).Formula:C21H14ClF3N4SColore e forma:SolidPeso molecolare:446.88Faldaprevir
CAS:Faldaprevir is an orally effective, selective, non-covalent HCV NS3/4A protease inhibitor with high inhibitory activity against HCV 1a and 1b genotype.Formula:C40H49BrN6O9SPurezza:99.04% - 99.19%Colore e forma:SolidPeso molecolare:869.82Freselestat quarterhydrate
ONO-6818 quarterhydrate: oral neutrophil elastase inhibitor, Ki 12.2 nM; >100x less effective on other proteases; strong anti-inflammatory.Formula:C23H30N6O5Colore e forma:SolidPeso molecolare:457.03Freselestat
CAS:Freselestat (ONO-6818) inhibits neutrophil elastase, reduces interleukin 8, C5B-9, and inflammation in cardiopulmonary bypass.Formula:C23H28N6O4Colore e forma:SolidPeso molecolare:452.51MeO-Suc-Ala-Ala-Pro-Ala-CMK
CAS:MeO-Suc-Ala-Ala-Pro-Ala-CMK (MSACK) is an inhibitor of human neutrophil elastase (HNE) with an IC50 of 20.3 μM. It effectively inhibits the hydrolysis of substrates like lung tissue elastin by HNE and is applicable in studies related to conditions such as chronic obstructive pulmonary disease (COPD).Formula:C20H31ClN4O7Colore e forma:SolidPeso molecolare:474.936HCV-IN-38
Potent oral HCV inhibitor HCV-IN-38 has 15 nM EC50, 431 SI, high efficacy, and low toxicity.Formula:C22H24ClF3N4O4Colore e forma:SolidPeso molecolare:500.9Ciluprevir
CAS:Ciluprevir is a selective HCV NS3 protease inhibitor, effective against non-genotype-1 HCV; less potent for genotypes 2/3.Formula:C40H50N6O8SPurezza:98%Colore e forma:SolidPeso molecolare:774.93RO5461111
CAS:RO5461111: Oral Cathepsin S inhibitor, IC50 of 0.4 nM (human) & 0.5 nM (mouse), reduces T/B cell activation, treats lung inflammation & lupus nephritis.Formula:C27H24F6N4O4SColore e forma:SolidPeso molecolare:614.56SD-7300
CAS:SD-7300 (SC-81490) functions as an orally active inhibitor targeting MMP-2, MMP-9, and MMP-13, exhibiting potent inhibition with K_i values of 0.03, 0.01, and 0.03 nM, respectively. By inhibiting these metalloproteinases, SD-7300 effectively reduces extracellular matrix degradation by tumor cells, thereby curbing their invasion and metastasis. Additionally, this compound acts as a dose-dependent inhibitor of mouse corneal angiogenesis and prevents interleukin-1-induced degradation of bovine cartilage. SD-7300 is applicable in the study of breast cancer.Formula:C21H30F3N3O7SColore e forma:SolidPeso molecolare:525.54Tyrosinase-IN-33
CAS:Tyrosinase-IN-33 (compound 5), a pyridine-based compound, acts as an effective inhibitor of diphenolase activity in mushroom tyrosinase. It significantly reduces enzyme activity with an IC50 of 9.0 μM.Formula:C19H17NS2Colore e forma:SolidPeso molecolare:323.48M826
M826, a non-peptide, potent, selective, and reversible caspase-3 inhibitor, exhibits an IC50 of 0.005 μM and demonstrates strong anti-apoptotic activity inFormula:C28H45N7O6Purezza:98%Colore e forma:SolidPeso molecolare:575.7BI-1942
CAS:<p>BI-1942 is a chymase inhibitor with an IC50 value of 0.4 nM against human chymase. It is applicable for research in ophthalmic diseases.</p>Formula:C24H26N4O4Colore e forma:SolidPeso molecolare:434.488Tyrosinase-IN-35
CAS:Tyrosinase-IN-35 (compound 6g), exhibiting a IC 50 value of 2.09 μM, serves as a more effective inhibitor of human tyrosinase compared to Kojic Acid (IC 50: 16.38 μM). At concentrations of 4 μM and 8 μM, this compound effectively lowers melanin levels in melanoma B16F10 cells in vitro.Formula:C17H15N5OSColore e forma:SolidPeso molecolare:337.40RJF02215
CAS:RJF02215, an MMP-9 inhibitor, exhibits growth inhibitory activity against the ovarian cancer cell line SKOV3. It is utilized in tumor research.Formula:C17H12ClN3OS3Colore e forma:SolidPeso molecolare:405.95Tilpisertib fosmecarbil
CAS:Tilpisertib fosmecarbil is a potent inhibitor of serine/threonine kinases with anti-inflammatory properties.Formula:C35H36ClN8O7PColore e forma:SolidPeso molecolare:747.14RXP03
CAS:RXP03 is an MMPs inhibitor with K_i values of 20 nM for MMP-2, 2.5 nM for MMP-8, 10 nM for MMP-9, 5 nM for MMP-11, and 105 nM for MMP-14 [1].Formula:C39H43N4O6PColore e forma:SolidPeso molecolare:694.76RBx-0597
CAS:RBx-0597 is a selective DPP-IV inhibitor with IC50 values of 32 nM, 31 nM, and 39 nM for human, mouse, and rat plasma DPP-IV, respectively. It is utilized in research focused on type 2 diabetes.Formula:C19H20F2N4O2Colore e forma:SolidPeso molecolare:374.384Gemigliptin tartrate hydrate
CAS:Gemigliptin (LC15-0444) tartrate hydrate is a selective, reversible, and competitive inhibitor of dipeptidyl peptidase 4 (DPP-4), with an IC50 value of 10.3 nM for human recombinant DPP-4. It exhibits strong anti-glycation properties and is used in research on advanced glycation end product-related diabetic complications.Formula:C22H27F8N5O9Colore e forma:SolidPeso molecolare:657.47UK-370106
CAS:UK-370106 is a potent and highly selective inhibitor of MMP-3 with IC50 of 23 nM and MMP-12 with IC50 of 42 nM, and potently inhibits cleavage of [3H]-Formula:C35H44N2O5Purezza:98%Colore e forma:SolidPeso molecolare:572.73SD-2590 HCl
CAS:SD-2590 HCl is an MMP-2,-3, -9, -8, 13, and -14 inhibitor.Formula:C22H26ClF3N2O7SPurezza:98%Colore e forma:SolidPeso molecolare:554.96PNU-248686A
CAS:PNU-248686A is an inhibitor of matrix metalloproteinase (MMP).Formula:C22H18ClNaO5S2Purezza:98%Colore e forma:SolidPeso molecolare:484.95Monosodium 2-sulfoterephthalate
CAS:<p>Monosodium 2-sulfoterephthalate (8) is an inhibitor of glutamate carboxypeptidase II.</p>Formula:C8H5NaO7SColore e forma:SolidPeso molecolare:268.176Faldaprevir sodium
CAS:Faldaprevir sodium: HCV treatment, inhibits NS3/NS4A protease, P-glycoprotein, CYP3A4, UGT1A1.Formula:C40H48BrN6NaO9SColore e forma:SolidPeso molecolare:891.81GSK-2878175
CAS:GSK-2878175, a NS5B inhibitor, is used potentially for the treatment of HCV infection.Formula:C27H23BClFN2O6SPurezza:98%Colore e forma:SolidPeso molecolare:568.81Pyridoxatin
CAS:Pyridoxatin: fungal metabolite; blocks TBARS production, prevents AAPH-induced hemolysis, and acts against C. albicans.Formula:C15H21NO3Colore e forma:SolidPeso molecolare:263.33Kallikrein-IN-1
CAS:Kallikrein-IN-1 (Formula A) is an inhibitor of the kinin-releasing enzyme Kallikrein.Formula:C28H26FN5O4Colore e forma:SolidPeso molecolare:515.54PLGLAG
CAS:PLGLAG is a peptide chain that acts as a linker in activatable cell-penetrating peptides (ACPPs). ACPPs containing the PLGLAG linker are primarily sensitive to MMP-2 and MMP-9 in vivo. PLGLAG is applicable in cancer research.Formula:C24H42N6O7Colore e forma:SolidPeso molecolare:526.63Valopicitabine dihydrochloride
CAS:Valopicitabine, a NS5B inhibitor, is used potentially for the treatment of HCV infection.Formula:C15H25ClN4O6Colore e forma:SolidPeso molecolare:392.84Antiplatelet agent 3
CAS:Antiplatelet agent 3 (Compound K-10) is a compound with antiplatelet aggregation activity, exhibiting IC50 values of 2.55, 3.22, and 2.09 mg/mL for platelet aggregation induced by ADP, AA, and COL, respectively. It holds potential for research in cardiovascular diseases.Formula:C38H32N2O5Colore e forma:SolidPeso molecolare:596.671Plodicitinib
CAS:Plodicitinib is an inhibitor of Janus tyrosine kinase 3/TEC family kinase, exhibiting anti-inflammatory properties.Formula:C19H22FN7O2Colore e forma:SolidPeso molecolare:399.422MMP-13-IN-1
CAS:MMP-13-IN-1, with an IC50 value of 16 nM, is a potent and selective inhibitor of MMP-13, suitable for atherosclerosis research [1].Formula:C19H16F3N3O3Colore e forma:SolidPeso molecolare:391.34AEP-IN-1
APE-IN-1, a potent AEP inhibitor (IC50: 89 nM), aids Alzheimer's diagnosis and drug research.Formula:C18H27N3O3Colore e forma:SolidPeso molecolare:333.43Dup-714
CAS:Dup-714 is a thrombin inhibitor.Formula:C21H33BN6O5Purezza:98%Colore e forma:SolidPeso molecolare:460.33JBIR-22
CAS:JBIR-22 is a natural inhibitor for protein−protein interaction of the homodimer of proteasome assembly factor 3.Formula:C23H33NO6Colore e forma:SolidPeso molecolare:419.51(1R,3S)-THCCA-Asn
(1R,3S)-THCCA-Asn (4j) is a selective inhibitor of thrombin (IC50: 0.07-0.14 μM) with anti-thrombotic effects.Formula:C24H24N4O6Colore e forma:SolidPeso molecolare:464.47RDN2150
CAS:RDN2150 (Compound 25), a ZAP-70 inhibitor with an IC50 of 14.6 nM, covalently binds to the C346 residue of ZAP-70, suppressing the expression of CD25 and CD69Formula:C28H29ClN8O4Colore e forma:SolidPeso molecolare:577.03AMG-222 tosylate
CAS:AMG-222 tosylate is a DPP-IV inhibitor in clinical development for type II diabetes.Formula:C39H47N9O6SColore e forma:SolidPeso molecolare:769.91JTK-109
CAS:JTK-109 is an inhibitor of hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor and inhibits G1b and G3a subgenomic replicons and recombinant enzymes.Formula:C37H33ClFN3O4Purezza:98.48% - 99.68%Colore e forma:SolidPeso molecolare:638.13Ref: TM-T27696
1mg313,00€5mg758,00€10mg1.035,00€25mg1.568,00€50mg2.118,00€100mg2.783,00€1mL*10mM (DMSO)Prezzo su richiestaIDX184
CAS:IDX184 is a potent, orally active, targeted HCV polymerase inhibitor and nucleoside polymerase.IDX184 effectively inhibits HCV polymerase (IC50=0.31 μM, Ki=52.3Formula:C25H35N6O9PSPurezza:97.15%Colore e forma:SolidPeso molecolare:626.62MIV-247
CAS:MIV-247 is a cathepsin S inhibitor that attenuates mechanically abnormal pain in preclinical neuropathic pain models and can be used to study myocardial injury.Formula:C17H24F3N3O4Purezza:99.27%Colore e forma:SolidPeso molecolare:391.39Vaniprevir
CAS:Vaniprevir is a competitive HCV NS3/4A protease inhibitor, an antiviral(hepatitis C virus) drug that acts directly and blocks the viral replication process.Formula:C38H55N5O9SPurezza:97.41%Colore e forma:SolidPeso molecolare:757.94PD 151746
CAS:PD151746: calpain inhibitor, Ki μ-calpain=0.26μM, Ki m-calpain=5.33μM; reduces oxLDL cytotoxicity.Formula:C11H8FNO2SPurezza:98.63% - ≥95%Colore e forma:SolidPeso molecolare:237.25Sebetralstat
CAS:<p>Sebetralstat (KVD900) is an inhibitor of plasma kallikrein and can be used in studies about metabolic diseases.</p>Formula:C26H26FN5O4Purezza:99.85%Colore e forma:SolidPeso molecolare:491.512,7,10,12-Tetraazatridecanoic acid, 4-hydroxy-12-methyl-9-(1-methylethyl)-13-[2-(1-methylethyl)-4-thiazolyl]-8,11-dioxo-3,6-bis(phenylmethyl)-, 5-thiazolylmethyl ester, (3S,4S,6S,9S)-
CAS:Formula:C37H48N6O5S2Purezza:≥98%Colore e forma:SolidPeso molecolare:720.9442ALLM
CAS:ALLM (Calpain inhibitor II), a potent calpain and cathepsin protease inhibitor, not only prevents neuronal cell death but also enhances chronic neurological function following spinal cord injury (SCI)[1][2].Formula:C19H35N3O4SPurezza:98%Colore e forma:White PowderPeso molecolare:401.563-Deazaadenosine
CAS:3-Deazaadenosine, an inhibitor of S-adenosylhomocysteine hydrolase with a Ki of 3.9 μM, exhibits anti-inflammatory, anti-proliferative, and anti-HIV activity.Formula:C11H14N4O4Purezza:98%Colore e forma:SolidPeso molecolare:266.25ABT-072 potassium trihydrate
CAS:ABT-072, also known as potassium trihydrate, is a highly effective non-nucleoside inhibitor of the HCV NS5B polymerase, administered orally. This compound exhibits potent activity against HCV GT1a (with an EC50 of 1 nM) and HCV GT1b (with an EC50 of 0.3 nM).Formula:C24H32KN3O8SColore e forma:SolidPeso molecolare:561.69IPN60090 dihydrochloride
CAS:IPN-60090 dihydrochloride is a potent and specific inhibitor of glutaminase 1 (GLS1) with a remarkable inhibition constant (IC50) of 31 nM. It does not exhibit any inhibitory activity against GLS-2. Furthermore, IPN-60090 dihydrochloride possesses outstanding physicochemical properties and pharmacokinetic characteristics in vivo. Therefore, it is a valuable compound for researching solid tumors, including lung and ovarian cancers.Formula:C24H29Cl2F3N8O3Colore e forma:SolidPeso molecolare:605.44MMP13-IN-2
CAS:MMP13-IN-2 is a highly potent, selective, and orally active inhibitor of MMP-13. It demonstrates exceptional potency against MMP-13, with an IC50 value of 0.036 nM, and exhibits selectivities greater than 1,500-fold over MMP-1, 3, 7, 8, 9, 14, and TACE. Moreover, MMP13-IN-2 possesses the capability to effectively inhibit collagen release from cartilage in vitro. Consequently, MMP13-IN-2 holds great potential for advancing research on collagenase-related diseases.Formula:C24H19FN6O4SColore e forma:SolidPeso molecolare:506.51Oxindole
CAS:<p>Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.Oxindole structure has been used in receptor tyrosine kinases (RTKs) inhibitors such as SU4984 and intedanib, the RTK family represents an important therapeutic target for anti-cancer drug development.</p>Formula:C8H7NOPurezza:99.34%Colore e forma:Off-White Crystalline PowderPeso molecolare:133.15Butabindide oxalate
CAS:CCK-inactivating serine protease (tripeptidyl peptidase II) inhibitorFormula:C19H27N3O6Purezza:98%Colore e forma:SolidPeso molecolare:393.43Davelizomib
CAS:<p>Davelizomib is a proteasome inhibitor that exhibits antineoplastic activity [1].</p>Formula:C21H26BF2N3O7Purezza:98%Colore e forma:SolidPeso molecolare:481.25
