Proteasi/Proteasoma
Gli inibitori delle proteasi e del proteasoma sono composti che bloccano l'attività delle proteasi e del proteasoma, che sono coinvolti nella degradazione e nel turnover delle proteine. Questi inibitori sono fondamentali per studiare la regolazione dell'omeostasi proteica, il controllo del ciclo cellulare e l'apoptosi. Gli inibitori delle proteasi e del proteasoma vengono anche utilizzati nel trattamento di malattie come il cancro, dove la degradazione anomala delle proteine svolge un ruolo nella progressione della malattia. Inibendo le proteasi o il proteasoma, questi composti possono indurre la morte cellulare nelle cellule tumorali e sono strumenti critici sia per la ricerca di base che per lo sviluppo terapeutico. Presso CymitQuimica, offriamo una vasta gamma di inibitori delle proteasi e del proteasoma di alta qualità per supportare la tua ricerca in biochimica, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Proteasi/Proteasoma"
- Acetil-CoA carbossilasi(36 prodotti)
- Cisteina proteasi(110 prodotti)
- DPP-4(20 prodotti)
- Glutaminasi(45 prodotti)
- Proteasi HIV(506 prodotti)
- PAI-1(26 prodotti)
- Inibitori della proteasi(50 prodotti)
- Ricettore attivato dalla proteasi(54 prodotti)
- Proteasoma(95 prodotti)
- Proteasi serina(55 prodotti)
- p97(15 prodotti)
Mostrare 3 più sottocategorie
Trovati 1095 prodotti di "Proteasi/Proteasoma"
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L-006235
CAS:L-006235 is a potent and reversible inhibitor of cathepsin K with IC50 of 0.25 nM.Formula:C24H30N6O2SPurezza:99.37%Colore e forma:SolidPeso molecolare:466.6Ref: TM-T21616
2mg42,00€5mg64,00€10mg97,00€25mg187,00€50mg316,00€100mg455,00€200mg635,00€1mL*10mM (DMSO)65,00€Tegobuvir
CAS:Tegobuvir (GS 333126) is a specific and covalent HCV NS5B polymerase inhibitor.Formula:C25H14F7N5Purezza:99.21%Colore e forma:SolidPeso molecolare:517.4Ref: TM-T17029
1mg88,00€5mg187,00€10mg311,00€25mg532,00€50mg750,00€100mg1.035,00€1mL*10mM (DMSO)213,00€Proteasome inhibitor IX
CAS:Proteasome inhibitor IX (PS-IX) is an inhibitor of chymotrypsin-like activity of the 20S proteasome (IC50 ~1 μM).Formula:C20H21B2NO5Purezza:99.77%Colore e forma:SolidPeso molecolare:377.01Grazoprevir hydrate
CAS:Grazoprevir: Hepatitis C protease inhibitor effective against various genotypes, including drug-resistant strains.Formula:C38H52N6O10SPurezza:98%Colore e forma:SolidPeso molecolare:784.927-Amino-4-methylcoumarin-3-acetic acid
CAS:7-Amino-4-methylcoumarin-3-acetic acid (7-Amino-4-methylcoumarin) is more suitable as a substrate for enteropeptidase than GD(4)K-NA.Formula:C12H11NO4Purezza:98.38%Colore e forma:SolidPeso molecolare:233.222-PMPA
CAS:2-PMPA (2-(Phosphonomethyl)pentanedioic acid) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) (IC50=300 pM).Formula:C6H11O7PPurezza:97.4% - 99.5%Colore e forma:SolidPeso molecolare:226.12FT011
CAS:FT011, a direct anti-fibrotic agent,attenuates cardiac remodelling and dysfunction in experimental diabetic cardiomyopathy.Formula:C20H17NO5Purezza:98.98%Colore e forma:SolidPeso molecolare:351.35VCH-916
CAS:VCH-916 is a new nonnucleoside inhibitor of HCV NS5B polymerase.Formula:C26H36KNO4SPurezza:98%Colore e forma:SolidPeso molecolare:497.73PythiDC
CAS:PythiDC is a selective collagen prolyl 4-hydroxylase inhibitor, neither causing general toxicity nor disrupting iron homeostasis.Formula:C10H6N2O4SPurezza:98.13%Colore e forma:SolidPeso molecolare:250.23HCV-IN-31
CAS:HCV-IN-31 is a HCV inhibitor with an EC50/EC95 of 15.7 μM.Formula:C12H17FN6O3Purezza:99.83%Colore e forma:SolidPeso molecolare:312.3Ivachtin
CAS:<p>Ivachtin (Caspase-3 Inhibitor VII) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor(IC50 = 23 nM) and is a modest inhibitor of the remaining</p>Formula:C20H21N3O7SPurezza:99.74%Colore e forma:SolidPeso molecolare:447.46VCH-916 free acid(1200133-34-1 free base)
CAS:VCH-916 is a novel nonnucleoside HCV NS5B polymerase inhibitor.Formula:C26H37NO4SPurezza:98.45%Colore e forma:SolidPeso molecolare:459.64Delavirdine mesylate
CAS:Delavirdine mesylate (BHAP-U 90152 (mesylate)) is a non-nucleoside reverse transcriptase inhibitor (NNRTI).Formula:C23H32N6O6S2Purezza:99.99%Colore e forma:Light Brown SolidPeso molecolare:552.67Coblopasvir
CAS:Coblopasvir is a pan-genotypic non-structural protein 5A (NS5A) inhibitor. It can be used to study chronic hepatitis C virus infection.Formula:C41H50N8O8Purezza:99.33%Colore e forma:SolidPeso molecolare:782.88Histatin 5 acetate
Histatin 5 acetate inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively.Formula:C135H199N51O35Purezza:98.72%Colore e forma:SolidPeso molecolare:3096.35Rolipram
CAS:Rolipram (SB 95952) is a phosphodiesterase 4 inhibitor with antidepressant properties.Formula:C16H21NO3Purezza:99.22% - >99.99%Colore e forma:SolidPeso molecolare:275.342-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one
CAS:2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one is an human neutrophil elastase inhibitor.Formula:C14H7BrClNO2Purezza:97.36%Colore e forma:SolidPeso molecolare:336.57Proteinase K
CAS:Proteinase K (Protease K) is a non-specific serine protease. Proteinase K hydrolyzes peptide bonds and is used for protein digestion. Cost-effective and quality-assured.Formula:C29H27N2O12PPurezza:98%Colore e forma:SolidPeso molecolare:626.511Ombitasvir
CAS:Ombitasvir (ABT-267) inhibits HCV protein NS5A, effective orally, EC50: 0.82-19.3 pM (genotypes 1-5), 366 pM (genotype 6a).Formula:C50H67N7O8Purezza:97.27% - 99.56%Colore e forma:SolidPeso molecolare:894.11Ref: TM-T7158
2mg43,00€5mg80,00€10mg111,00€25mg227,00€50mg329,00€100mg487,00€500mg1.026,00€1mL*10mM (DMSO)111,00€Trovirdine
CAS:Trovirdine (LY300046) is a thiourea non-nucleoside reverse transcriptase inhibitor.Formula:C13H13BrN4SPurezza:98.12% - 98.50%Colore e forma:SolidPeso molecolare:337.24Boceprevir
CAS:Boceprevir (SCH 503034), an oral HCV NS3 protease inhibitor, has a Ki of 14 nM and EC90 of 350 nM.Formula:C27H45N5O5Purezza:95% - 99.16%Colore e forma:SolidPeso molecolare:519.68Ref: TM-T4988
1mg35,00€5mg70,00€10mg96,00€25mg144,00€50mg187,00€100mg274,00€200mg378,00€1mL*10mM (DMSO)80,00€Lersivirine
CAS:Lersivirine (UK-453061)(UK 453061) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for HIV infection therapy.Formula:C17H18N4O2Purezza:98.01%Colore e forma:SolidPeso molecolare:310.35Clemizole
CAS:Clemizole is an H1 histamine receptor antagonist, can inhibit NS4B's RNA binding and hepatitis C virus (HCV) replication.Formula:C19H20ClN3Purezza:98% - 99.65%Colore e forma:SolidPeso molecolare:325.84Ref: TM-T1822
1mg44,00€5mg87,00€10mg106,00€25mg160,00€50mg270,00€100mg487,00€500mg1.026,00€1mL*10mM (DMSO)87,00€Vesnarinone
CAS:Vesnarinone (Arkin) (INN) is a mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, butFormula:C22H25N3O4Purezza:96.69% - 98.13%Colore e forma:SolidPeso molecolare:395.45Ref: TM-T3465
2mg35,00€5mg52,00€10mg80,00€25mg117,00€100mg313,00€200mg452,00€1mL*5mM (DMSO)49,00€50mg*5mM (DMSO)210,00€Sofosbuvir
CAS:Sofosbuvir (GS 7977) is a uridine monophosphate analog inhibitor of hepatitis C virus (HCV) polymerase NS5B that is used as an antiviral agent in the treatmentFormula:C22H29FN3O9PPurezza:99.77% - 99.82%Colore e forma:SolidPeso molecolare:529.45ONX-0914
CAS:ONX-0914 (PR-957) is an effective and specific immunoproteasome inhibitor, which has minimal cross-reactivity for the constitutive proteasome.Formula:C31H40N4O7Purezza:98.24% - 99.31%Colore e forma:SolidPeso molecolare:580.67NBD-557
CAS:<p>NBD-557 is a potentially HIV-1 inhibitor.</p>Formula:C17H24BrN3O2Purezza:99.52%Colore e forma:SolidPeso molecolare:382.3Ac-DEVD-AMC
CAS:<p>Ac-DEVD-AMC (AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN) is the substrate of Caspase-3 .</p>Formula:C30H37N5O13Purezza:98.20%Colore e forma:White PowderPeso molecolare:675.64(R)-MG-132
CAS:(R)-MG-132 (Z-Leu-D-leu-leu-al) is the enantiomer of MG-132. (R)-MG-132 stereoisomer is a more potent proteasome inhibitor than MG-132.Formula:C26H41N3O5Purezza:99.90%Colore e forma:SolidPeso molecolare:475.62Ref: TM-T12628
2mg40,00€5mg60,00€10mg84,00€25mg127,00€50mg187,00€100mg283,00€200mg419,00€1mL*10mM (DMSO)74,00€2-Benzylsuccinic acid
CAS:2-Benzylsuccinic acid (DL-Benzylsuccinic acid) is a bacterial xenobiotic metabolite.Formula:C11H12O4Purezza:99.01% - ≥95%Colore e forma:SolidPeso molecolare:208.21Ilomastat
CAS:<p>Ilomastat (GM6001) (GM6001, Galardin) is a broad spectrum matrix metalloprotease (MMP) inhibitor.</p>Formula:C20H28N4O4Purezza:97.04% - 99.51%Colore e forma:SolidPeso molecolare:388.46Trelagliptin succinate
CAS:Trelagliptin succinate (SYR-472 succinate) is a long-acting inhibitor of dipeptidyl peptidase-4 (DPP-4), being developed for the treatment of type 2 diabetes (Formula:C22H26FN5O6Purezza:99.27% - 99.92%Colore e forma:SolidPeso molecolare:475.47Tenofovir alafenamide hemifumarate
CAS:<p>Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an oral phosphonoamidate prodrug of the HIV reverse transcriptase nucleotide inhibitor tenofovir.</p>Formula:C21H29N6O5PC4H4O4Purezza:99.33% - 99.96%Colore e forma:SolidPeso molecolare:534.51Elbasvir
CAS:<p>Elbasvir (MK-8742) is an NS5A inhibitor developed for chronic HCV treatment.</p>Formula:C49H55N9O7Purezza:98.95% - 99.85%Colore e forma:SolidPeso molecolare:882.02S-methyl-KE-298
CAS:S-methyl-KE-298 is the second main metabolite in plasma,is a methyl conjugate of deacetyl-KE-298.KE-298 inhibits matrix metalloproteinase (MMP-1) productionFormula:C13H16O3SPurezza:97.33%Colore e forma:SolidPeso molecolare:252.33Ref: TM-T4282
1mg88,00€5mg210,00€10mg338,00€25mg625,00€50mg938,00€100mg1.264,00€1mL*10mM (DMSO)188,00€SB-3CT
CAS:SB-3CT is a potent and specific gelatinase inhibitor for MMP-2(Ki=13.9 nM) and MMP-9(Ki=600 nM).Formula:C15H14O3S2Purezza:98% - 99.38%Colore e forma:SolidPeso molecolare:306.4Ref: TM-T2009
1mg48,00€2mg65,00€5mg88,00€10mg159,00€25mg246,00€50mg368,00€100mg547,00€500mg1.198,00€1mL*10mM (DMSO)88,00€Odanacatib
CAS:Odanacatib is an inhibitor of cathepsin K with potential anti-osteoporotic activity.Formula:C25H27F4N3O3SPurezza:98.53% - 99.53%Colore e forma:SolidPeso molecolare:525.56Ref: TM-T6035
2mg35,00€5mg52,00€10mg80,00€25mg120,00€50mg188,00€100mg354,00€200mgPrezzo su richiesta1mL*10mM (DMSO)60,00€Picolamine
CAS:Picolamine acts as a potential inhibitor of DPP-4.Formula:C6H8N2Purezza:98.3%Colore e forma:Light Yellow LiquidPeso molecolare:108.14BMS-707035
CAS:BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2.Formula:C17H19FN4O5SPurezza:99.78%Colore e forma:SolidPeso molecolare:410.42CGS 27023A
CAS:CGS 27023A is a non-peptidic, potent, and orally active stromelysin inhibitor.Formula:C18H24ClN3O5SPurezza:99.08%Colore e forma:SolidPeso molecolare:429.924-Chloro-2-(trifluoroacetyl)aniline hydrochloride
CAS:<p>4-Chloro-2-(trifluoroacetyl)aniline hydrochloride is an inhibitor of HIV-1 RT (HIV reverse transcriptase) .</p>Formula:C8H6Cl2F3NOPurezza:97.15%Colore e forma:SolidPeso molecolare:260.04Telaprevir
CAS:Telaprevir (Incivek) (VX-950) is an effective inhibitor of HCV NS3-4A serine protease (IC50: 0.35 μM).Formula:C36H53N7O6Purezza:96.9% - 98.89%Colore e forma:SolidPeso molecolare:679.85Darunavir
CAS:Darunavir (TMC114) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS.Formula:C27H37N3O7SPurezza:99.67% - 99.76%Colore e forma:White Amorphous SolidPeso molecolare:547.66Elvitegravir
CAS:Elvitegravir (JTK-303) is an HIV integrase inhibitor and CYP2C9 inducer.Formula:C23H23ClFNO5Purezza:98.43% - 99.57%Colore e forma:SolidPeso molecolare:447.88NSC 405020
CAS:NSC 405020 is a noncatalytic inhibitor of MT1-MMP.Formula:C12H15Cl2NOPurezza:96.93% - 99.07%Colore e forma:SolidPeso molecolare:260.16Etravirine
CAS:Etravirine (R165335) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.Formula:C20H15BrN6OPurezza:97.61% - 99.74%Colore e forma:White To Off-White SolidPeso molecolare:435.28Ref: TM-T2551
2mg35,00€5mg52,00€10mg80,00€25mg149,00€50mg216,00€100mg329,00€200mg485,00€1mL*10mM (DMSO)52,00€Belnacasan
CAS:Belnacasan (VX-765) is an orally active IL-converting enzyme/caspase-1 inhibitor.Formula:C24H33ClN4O6Purezza:96.53% - 99.5%Colore e forma:SolidPeso molecolare:508.99Ref: TM-T6090
2mg37,00€5mg50,00€10mg86,00€25mg170,00€50mg235,00€100mg419,00€200mg617,00€1mL*10mM (DMSO)56,00€Lusutrombopag
CAS:Lusutrombopag (Mulpleta) is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist for chronic liver disease (CLD) patients withFormula:C29H32Cl2N2O5SPurezza:99.96%Colore e forma:SolidPeso molecolare:591.55Ref: TM-TQ0223
1mg64,00€2mg92,00€5mg137,00€10mg208,00€25mg416,00€50mg628,00€100mg938,00€200mg1.293,00€1mL*10mM (DMSO)170,00€Batimastat
CAS:Batimastat (BB94) (BB-94) is an effective, broad-spectrum matrix metalloprotease (MMP) inhibitor.Formula:C23H31N3O4S2Purezza:98.15% - 99.5%Colore e forma:SolidPeso molecolare:477.64Bemnifosbuvir hemisulfate
CAS:Bemnifosbuvir hemisulfate (AT-527) is a potent inhibitor of HCV virus replication.Formula:C48H68F2N14O18P2SPurezza:99.98%Colore e forma:SolidPeso molecolare:1261.15
