Proteasi/Proteasoma
Gli inibitori delle proteasi e del proteasoma sono composti che bloccano l'attività delle proteasi e del proteasoma, che sono coinvolti nella degradazione e nel turnover delle proteine. Questi inibitori sono fondamentali per studiare la regolazione dell'omeostasi proteica, il controllo del ciclo cellulare e l'apoptosi. Gli inibitori delle proteasi e del proteasoma vengono anche utilizzati nel trattamento di malattie come il cancro, dove la degradazione anomala delle proteine svolge un ruolo nella progressione della malattia. Inibendo le proteasi o il proteasoma, questi composti possono indurre la morte cellulare nelle cellule tumorali e sono strumenti critici sia per la ricerca di base che per lo sviluppo terapeutico. Presso CymitQuimica, offriamo una vasta gamma di inibitori delle proteasi e del proteasoma di alta qualità per supportare la tua ricerca in biochimica, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Proteasi/Proteasoma"
- Acetil-CoA carbossilasi(36 prodotti)
- Cisteina proteasi(110 prodotti)
- DPP-4(21 prodotti)
- Glutaminasi(45 prodotti)
- Proteasi HIV(508 prodotti)
- PAI-1(26 prodotti)
- Inibitori della proteasi(50 prodotti)
- Ricettore attivato dalla proteasi(54 prodotti)
- Proteasoma(95 prodotti)
- Proteasi serina(55 prodotti)
- p97(15 prodotti)
Mostrare 3 più sottocategorie
Trovati 1082 prodotti di "Proteasi/Proteasoma"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Asunaprevir
CAS:Asunaprevir (BMS-650032) is an effective hepatitis C virus (HCV) NS3 protease inhibitor.Formula:C35H46ClN5O9SPurezza:99.34% - 99.8%Colore e forma:SolidPeso molecolare:748.29Ref: TM-T4474
1mg52,00€5mg111,00€10mg180,00€25mg354,00€50mg540,00€100mg778,00€500mg1.605,00€1mL*10mM (DMSO)173,00€PSI-6130
CAS:PSI-6130 (R 1656) is a potent and selective HCV NS5B polymerase inhibitor. PSI-6130 inhibits HCV replication with a mean IC50 of 0.6 μM.Formula:C10H14FN3O4Purezza:98.63% - 99.79%Colore e forma:SolidPeso molecolare:259.23Ref: TM-T7607
1mg38,00€5mg94,00€10mg122,00€25mg212,00€50mg313,00€100mg457,00€200mg618,00€1mL*10mM (DMSO)73,00€Rilpivirine
CAS:Rilpivirine (R278474) is a diarylpyrimidine derivative and reverse transcriptase inhibitor with antiviral activity against HIV-1 that is used in the treatmentFormula:C22H18N6Purezza:97.22% - 98.83%Colore e forma:SolidPeso molecolare:366.42Ref: TM-T2330
2mg38,00€5mg55,00€10mg88,00€25mg145,00€50mg243,00€100mg338,00€200mg500,00€1mL*10mM (DMSO)62,00€Z-Gly-Gly-Arg-AMC TFA (66216-78-2 free base)
CAS:Z-Gly-Gly-Arg-AMC TFA (66216-78-2 free base) is a thrombin-specific fluorogenic substrate for testing thrombin generation in PRP and platelet-poor plasma (PPP).Formula:C30H34F3N7O9Purezza:99.77%Colore e forma:SolidPeso molecolare:693.63Ref: TM-T8556
1mg88,00€5mg170,00€10mg259,00€25mg425,00€50mg598,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)251,00€BMS-707035
CAS:BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2.Formula:C17H19FN4O5SPurezza:99.78%Colore e forma:SolidPeso molecolare:410.42EIDD-1931
CAS:<p>EIDD-1931 (Beta-d-N4-hydroxycytidine) is a ribonucleoside analog with antiviral activity. It inhibits replication of SARS-CoV, MERS-CoV, and SARS-CoV-2.</p>Formula:C9H13N3O6Purezza:99.14% - 99.73%Colore e forma:SolidPeso molecolare:259.22RN-18
CAS:RN-18 is an inhibitor of HIV-1 viral infectivity factor (IC50: 6 μM in nonpermissive H9 cells).Formula:C20H16N2O4SPurezza:97.21% - 98.39%Colore e forma:SolidPeso molecolare:380.423-O-Ethyl-L-ascorbic acid
CAS:3-O-Ethyl-L-ascorbic acid is a cosmetic tyrosinase inhibitor with whitening ability and is a stabilized vitamin C derivative.Formula:C8H12O6Purezza:97.35% - 99.99%Colore e forma:White To Very Pale Yellow Crystalline Powder Solid PowderPeso molecolare:204.18Fulacimstat
CAS:Fulacimstat (BAY1142524) (BAY1142524) is a chymase inhibitor, with IC50s of 3, 4 nM for hamster and human chymase enzyme, respectively.Formula:C23H16F3N3O6Purezza:99.77%Colore e forma:SolidPeso molecolare:487.38Ref: TM-TQ0035
1mg106,00€5mg227,00€10mg329,00€25mg540,00€50mg777,00€100mg1.026,00€1mL*10mM (DMSO)244,00€Chlorcyclizine
CAS:CHLORCYCLIZINE is a histamine H1 antagonist and a potent hepatitis C virus (HCV) entry inhibitor.Formula:C18H21ClN2Purezza:98.75%Colore e forma:SolidPeso molecolare:300.83(S,S)-TAPI-1
CAS:"(S,S)-TAPI-1, an isomer of TAPI-1, inhibits MMPs and TACE (ADAM17), reducing cell surface protein shedding."Formula:C26H37N5O5Colore e forma:SolidPeso molecolare:499.6KGP94
CAS:KGP94 is a potent, selective, and competitive inhibitor of the lysosomal endopeptidase enzyme.Formula:C14H12BrN3OSPurezza:99.6%Colore e forma:SolidPeso molecolare:350.23Ref: TM-T27730
1mg69,00€5mg145,00€10mg226,00€25mg379,00€50mg538,00€100mg730,00€200mg979,00€1mL*10mM (DMSO)160,00€Tenofovir alafenamide hemifumarate
CAS:<p>Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an oral phosphonoamidate prodrug of the HIV reverse transcriptase nucleotide inhibitor tenofovir.</p>Formula:C21H29N6O5PC4H4O4Purezza:99.33% - 99.96%Colore e forma:SolidPeso molecolare:534.51ML281
CAS:ML281 is a potent and selective STK33 inhibitor with IC50 of 14 nM.Formula:C22H19N3O2SPurezza:99.12% - 99.87%Colore e forma:SolidPeso molecolare:389.47Ref: TM-T3423
1mg35,00€5mg80,00€10mg97,00€25mg188,00€50mg311,00€100mg500,00€500mg1.093,00€1mL*10mM (DMSO)88,00€S-methyl-KE-298
CAS:S-methyl-KE-298 is the second main metabolite in plasma,is a methyl conjugate of deacetyl-KE-298.KE-298 inhibits matrix metalloproteinase (MMP-1) productionFormula:C13H16O3SPurezza:97.33%Colore e forma:SolidPeso molecolare:252.33Ref: TM-T4282
1mg88,00€5mg210,00€10mg338,00€25mg625,00€50mg938,00€100mg1.264,00€1mL*10mM (DMSO)188,00€HZ-1157
CAS:HZ-1157 (DHFR-inhibitor) is a hepatitis C virus (HCV) inhibitor with inhibitory activities toward HCV NS3/4A protease.Formula:C12H16N4OPurezza:98.23%Colore e forma:SolidPeso molecolare:232.28Darunavir
CAS:Darunavir (TMC114) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS.Formula:C27H37N3O7SPurezza:99.67% - 99.76%Colore e forma:White Amorphous SolidPeso molecolare:547.66PSI-6206
CAS:PSI-6206 (RO 2433) (RO2433) is a selective HCV RNA polymerase inhibitor.Formula:C10H13FN2O5Purezza:98% - 99.79%Colore e forma:SolidPeso molecolare:260.22VCH-916 free acid(1200133-34-1 free base)
CAS:VCH-916 is a novel nonnucleoside HCV NS5B polymerase inhibitor.Formula:C26H37NO4SPurezza:98.45%Colore e forma:SolidPeso molecolare:459.64Ivachtin
CAS:<p>Ivachtin (Caspase-3 Inhibitor VII) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor(IC50 = 23 nM) and is a modest inhibitor of the remaining</p>Formula:C20H21N3O7SPurezza:99.74%Colore e forma:SolidPeso molecolare:447.46SB-3CT
CAS:SB-3CT is a potent and specific gelatinase inhibitor for MMP-2(Ki=13.9 nM) and MMP-9(Ki=600 nM).Formula:C15H14O3S2Purezza:98% - 99.38%Colore e forma:SolidPeso molecolare:306.4Ref: TM-T2009
1mg48,00€2mg65,00€5mg88,00€10mg159,00€25mg246,00€50mg368,00€100mg547,00€500mg1.198,00€1mL*10mM (DMSO)88,00€Picolamine
CAS:Picolamine acts as a potential inhibitor of DPP-4.Formula:C6H8N2Purezza:98.3%Colore e forma:Light Yellow LiquidPeso molecolare:108.14Etravirine
CAS:Etravirine (R165335) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.Formula:C20H15BrN6OPurezza:97.61% - 99.74%Colore e forma:White To Off-White SolidPeso molecolare:435.28Ref: TM-T2551
2mg35,00€5mg52,00€10mg80,00€25mg149,00€50mg216,00€100mg329,00€200mg485,00€1mL*10mM (DMSO)52,00€CGS 27023A
CAS:CGS 27023A is a non-peptidic, potent, and orally active stromelysin inhibitor.Formula:C18H24ClN3O5SPurezza:99.08%Colore e forma:SolidPeso molecolare:429.92Alloxan monohydrate
CAS:<p>Alloxan Monohydrate is a glucose analog used to induce diabetes by destroying beta-cells.</p>Formula:C4H4N2O5Purezza:99.01% - 99.42%Colore e forma:Off-White To Beige-Yellowish Crystalline PowderPeso molecolare:160.09PythiDC
CAS:PythiDC is a selective collagen prolyl 4-hydroxylase inhibitor, neither causing general toxicity nor disrupting iron homeostasis.Formula:C10H6N2O4SPurezza:98.13%Colore e forma:SolidPeso molecolare:250.234-Chloro-2-(trifluoroacetyl)aniline hydrochloride
CAS:<p>4-Chloro-2-(trifluoroacetyl)aniline hydrochloride is an inhibitor of HIV-1 RT (HIV reverse transcriptase) .</p>Formula:C8H6Cl2F3NOPurezza:97.15%Colore e forma:SolidPeso molecolare:260.04Telaprevir
CAS:Telaprevir (Incivek) (VX-950) is an effective inhibitor of HCV NS3-4A serine protease (IC50: 0.35 μM).Formula:C36H53N7O6Purezza:96.9% - 98.89%Colore e forma:SolidPeso molecolare:679.85Lusutrombopag
CAS:Lusutrombopag (Mulpleta) is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist for chronic liver disease (CLD) patients withFormula:C29H32Cl2N2O5SPurezza:99.96%Colore e forma:SolidPeso molecolare:591.55Ref: TM-TQ0223
1mg64,00€2mg92,00€5mg137,00€10mg208,00€25mg416,00€50mg628,00€100mg938,00€200mg1.293,00€1mL*10mM (DMSO)170,00€Elvitegravir
CAS:Elvitegravir (JTK-303) is an HIV integrase inhibitor and CYP2C9 inducer.Formula:C23H23ClFNO5Purezza:98.43% - 99.57%Colore e forma:SolidPeso molecolare:447.88FT011
CAS:FT011, a direct anti-fibrotic agent,attenuates cardiac remodelling and dysfunction in experimental diabetic cardiomyopathy.Formula:C20H17NO5Purezza:98.98%Colore e forma:SolidPeso molecolare:351.35Dabigatran Etexilate Mesylate
CAS:Dabigatran Etexilate Mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor.Formula:C34H41N7O5·CH4O3SPurezza:99.91%Colore e forma:SolidPeso molecolare:723.84Ref: TM-T5133
5mg42,00€10mg57,00€25mg74,00€50mg95,00€100mg111,00€200mg169,00€500mg240,00€1mL*10mM (DMSO)64,00€Anagliptin hydrochloride
CAS:Anagliptin (SK-0403) hydrochloride: potent, selective oral DPP-4 inhibitor; IC50: DPP-4 3.8 nM, DPP-8 68 nM, DPP-9 60 nM.Formula:C19H26ClN7O2Colore e forma:SolidPeso molecolare:419.91Batimastat
CAS:Batimastat (BB94) (BB-94) is an effective, broad-spectrum matrix metalloprotease (MMP) inhibitor.Formula:C23H31N3O4S2Purezza:98.15% - 99.5%Colore e forma:SolidPeso molecolare:477.642,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)-
CAS:2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)- (Ulinastatin) ,as an urinary trypsin inhibitor (UTI), is a glycoprotein that is isolated from healthy human urineFormula:C13H16O3Purezza:99.53% - 99.81%Colore e forma:SolidPeso molecolare:220.26Ref: TM-T8802
1mg87,00€5mg172,00€10mg258,00€25mg425,00€50mg598,00€100mg810,00€500mg1.605,00€1mL*10mM (DMSO)155,00€Delavirdine mesylate
CAS:Delavirdine mesylate (BHAP-U 90152 (mesylate)) is a non-nucleoside reverse transcriptase inhibitor (NNRTI).Formula:C23H32N6O6S2Purezza:99.99%Colore e forma:Light Brown SolidPeso molecolare:552.67Glutaminase C-IN-1
CAS:Glutaminase C-IN-1 (Compound 968) is a Glutaminase C allosteric inhibitor.Formula:C27H27BrN2OPurezza:99.68% - >99.99%Colore e forma:SolidPeso molecolare:475.42Ref: TM-T3964
2mg42,00€5mg60,00€10mg87,00€25mg162,00€50mg273,00€100mg378,00€200mg557,00€1mL*10mM (DMSO)67,00€Coblopasvir
CAS:Coblopasvir is a pan-genotypic non-structural protein 5A (NS5A) inhibitor. It can be used to study chronic hepatitis C virus infection.Formula:C41H50N8O8Purezza:99.33%Colore e forma:SolidPeso molecolare:782.88Ledipasvir
CAS:Ledipasvir (GS-5885) is a Hepatitis C Virus NS5A Inhibitor.Formula:C49H54F2N8O6Purezza:99.96%Colore e forma:SolidPeso molecolare:889Ref: TM-T6200
1mg38,00€2mg49,00€5mg79,00€10mg88,00€25mg159,00€50mg256,00€100mg444,00€500mg1.017,00€1mL*10mM (DMSO)88,00€Teneligliptin
CAS:Teneligliptin (MP-513), potent DPP-4 inhibitor, IC50 ~1 nM, blocks DPP-4 in human/rat plasma and recombinant forms.Formula:C22H30N6OSPurezza:99.73%Colore e forma:SolidPeso molecolare:426.58(1S,2R)-Alicapistat
CAS:(1S,2R)-Alicapistat inhibits calpains 1 and 2, shows promise for Alzheimer's, and has an IC50 of 395 nM.Formula:C25H27N3O4Purezza:99.60%Colore e forma:SoildPeso molecolare:433.5Ref: TM-T60150
1mg67,00€5mg150,00€10mg208,00€25mg316,00€50mg423,00€100mg567,00€1mL*10mM (DMSO)170,00€Rilpivirine HCl
CAS:Rilpivirine HCl (Rilpivirine hydrochloride) is an NNRTI inhibitor with antiviral activity that inhibits the HIV virus.Formula:C22H19ClN6Purezza:99.48%Colore e forma:SolidPeso molecolare:402.88KP-457
CAS:KP-457 is a ADAM17 and a TNFα converting enzyme TACE inhibitor that blocks the production of soluble TNF (sTNF).Formula:C21H24N2O7S2Purezza:98.33%Colore e forma:SolidPeso molecolare:480.56Ref: TM-T77778
1mg92,00€5mg216,00€10mg354,00€25mg655,00€50mg1.035,00€100mg1.406,00€1mL*10mM (DMSO)230,00€Methylchloroisothiazolinone/Methylisothiazolinone Mixture
CAS:Methylchloroisothiazolinone/Methylisothiazolinone Mixture (Kathon 886MW),a preservative, activates MMPs in human bronchial epithelial cells.Formula:C8H9ClN2O2S2Purezza:99.76%Colore e forma:SolidPeso molecolare:264.75Sitagliptin phosphate monohydrate
CAS:Sitagliptin phosphate monohydrate (MK-0431 phosphate monohydrate) is a potent inhibitor of DPP-IV with IC50 of 19 nM in Caco-2 cell extracts.Formula:C16H15F6N5O·H3PO4·H2OPurezza:99.85% - 99.98%Colore e forma:White Or Almost White Crystalline PowderPeso molecolare:523.33(R)-Trolox
CAS:(R)-Trolox is a selective tyrosinase inhibitor used in food, cosmetics, and pharmaceutical products.Formula:C14H18O4Purezza:99.88%Colore e forma:SolidPeso molecolare:250.29Danoprevir
CAS:Danoprevir (RG7227) is a peptidomimetic inhibitor of the NS3/4A protease(IC50=0.2-3.5 nM) of hepatitis C virus (HCV).Formula:C35H46FN5O9SPurezza:98% - 99.80%Colore e forma:SolidPeso molecolare:731.83Nelfinavir
CAS:Nelfinavir (AG1341), with Ki=2 nM, is an HIV treatment and broad-spectrum anticancer drug.Formula:C32H45N3O4SPurezza:98.16% - 99.5%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:567.78PSI
CAS:PSI is a proteasome inhibitor.Formula:C32H50N4O8Purezza:97% - 98.33%Colore e forma:SolidPeso molecolare:618.76Anti-Human/Mouse denatured collagen type-I Antibody
Anti-Human/Mouse denatured collagen type-I Antibody (XL313) is an IgG1, κ inhibitor derived from mice, targeting denatured collagen type-I in both human and mouse.Colore e forma:Odour Liquid
