Proteasi/Proteasoma
Gli inibitori delle proteasi e del proteasoma sono composti che bloccano l'attività delle proteasi e del proteasoma, che sono coinvolti nella degradazione e nel turnover delle proteine. Questi inibitori sono fondamentali per studiare la regolazione dell'omeostasi proteica, il controllo del ciclo cellulare e l'apoptosi. Gli inibitori delle proteasi e del proteasoma vengono anche utilizzati nel trattamento di malattie come il cancro, dove la degradazione anomala delle proteine svolge un ruolo nella progressione della malattia. Inibendo le proteasi o il proteasoma, questi composti possono indurre la morte cellulare nelle cellule tumorali e sono strumenti critici sia per la ricerca di base che per lo sviluppo terapeutico. Presso CymitQuimica, offriamo una vasta gamma di inibitori delle proteasi e del proteasoma di alta qualità per supportare la tua ricerca in biochimica, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Proteasi/Proteasoma"
- Acetil-CoA carbossilasi(36 prodotti)
- Cisteina proteasi(110 prodotti)
- DPP-4(20 prodotti)
- Glutaminasi(45 prodotti)
- Proteasi HIV(506 prodotti)
- PAI-1(26 prodotti)
- Inibitori della proteasi(50 prodotti)
- Ricettore attivato dalla proteasi(54 prodotti)
- Proteasoma(95 prodotti)
- Proteasi serina(55 prodotti)
- p97(15 prodotti)
Mostrare 3 più sottocategorie
Trovati 1095 prodotti di "Proteasi/Proteasoma"
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IETD-CHO TFA
IETD-CHO TFA (Caspase-8-IN-1) functions as a potent inhibitor of caspase-8 [1].Formula:C95H162N20O26·xC2HF3O2Purezza:98%Colore e forma:SolidPeso molecolare:2000.42 (free acid)Ac-PAL-AMC
CAS:Ac-PAL-AMC is a β1i/LMP2-specific substrate that fluoresces when cleaved; useful for measuring immunoproteasome activity.Formula:C26H34N4O6Colore e forma:SolidPeso molecolare:498.576,6′-Dihydroxythiobinupharidine
CAS:6,6′-Dihydroxythiobinupharidine, a cysteine proteases inhibitor, amplifies DNA cleavage facilitated by human topoisomerase IIα and IIβ by approximately 8-foldFormula:C30H42N2O4SColore e forma:SolidPeso molecolare:526.73Bortezomib analog
Bortezomibanalog (Compound 13) is an analog of Bortezomib, functioning as an active control ligand for the 20S proteasome subunit β5.Colore e forma:Odour SolidGrazoprevir potassium salt
CAS:<p>Grazoprevir, a drug for hepatitis C, is a second-gen NS3/4a protease inhibitor.</p>Formula:C38H49KN6O9SColore e forma:SolidPeso molecolare:805Rivulariapeptolides 1185
Rivulariapeptolides 1185 inhibits serine proteases; IC50: chymotrypsin 13.17 nM, elastase 23.59 nM, proteinase K 55.26 nM.Formula:C61H87N9O15Colore e forma:SolidPeso molecolare:1186.39Fotagliptin benzoate
CAS:Fotagliptin benzoate, a DPP-4 inhibitor (IC50=2.27 nM), is safe in rats/dogs, useful for Type 2 diabetes research.Formula:C24H25FN6O3Colore e forma:SolidPeso molecolare:464.4915,16-Dihydrotanshindiol C
15,16-Dihydrotanshindiol C is a useful organic compound for research related to life sciences and the catalog number is T123985.Formula:C18H18O5Colore e forma:SolidPeso molecolare:314.337FiVe1
CAS:<p>FiVe1 is a vimentin-binding compound that disrupts mitosis in cancer cells, causing cell death, with an IC50 of 234 nM in FOXC2-HMLER.</p>Formula:C18H16Cl2N4Purezza:99.67%Colore e forma:SolidPeso molecolare:359.25AAF-CMK (trifluoroacetate salt)
CAS:TPPII, a serine peptidase, cleaves tripeptides from oligopeptides. AAF-CMK irreversibly inhibits TPPII at 10-100 μM, sparing proteasome activity.Formula:C18H23ClF3N3O5Colore e forma:SolidPeso molecolare:453.84Talopeptin
CAS:Talopeptin is a specific thermolysin inhibitor.Formula:C23H34N3O10PPurezza:98%Colore e forma:SolidPeso molecolare:543.50NS5A-IN-4
CAS:NS5A-IN-4 (Compound 1.12) is a hepatitis C inhibitor effective against multiple genotypes, with IC50 values ranging from 1.2 to 2296 pM.Formula:C47H48N8O6Colore e forma:SolidPeso molecolare:820.93Tyrosinase/elastase-IN-1
Tyrosinase/elastase-IN-1, a triterpenoid extracted from the leaves of Rubus fraxinifolius, exhibits inhibitory activities against both tyrosinase and elastaseFormula:C33H52O5Colore e forma:SolidPeso molecolare:528.76MMP-9-IN-6
CAS:MMP-9-IN-6: MMP-9 inhibitor, IC50 of 50 µM, anti-ulcer, potential anti-tumor, for tissue repair studies.Formula:C25H19NO2Purezza:98.96%Colore e forma:SoildPeso molecolare:365.42α 1 Antichymotrypsin, Human Plasma
CAS:Alpha 1 Antichymotrypsin, Human Plasma is an inhibitor of serine proteases. This compound is present in amyloid lesions associated with Alzheimer's disease and can be utilized in Alzheimer's research.Colore e forma:SolidRadalbuvir
CAS:Radalbuvir (GS-9669) is an investigational antiviral agent for the treatment of hepatitis C virus (HCV) infection as an NS5B inhibitor.Formula:C30H41NO6SColore e forma:SolidPeso molecolare:543.71OM-7D3-B3
OM-7D3-B3 is a monoclonal antibody that targets human tight junction protein 1 (CLDN1) with a dissociation constant (Kd) of 4 nM. This antibody inhibits the role of CLDN1 in the cellular entry of the hepatitis C virus (HCV) and holds potential for research into HCV infection.Sulodexide
CAS:Sulodexide is an orally administered combination of glycosaminoglycans, consisting of low molecular weight heparin (80%) and dermatan sulfate (20%). It demonstrates antithrombotic properties by interacting with antithrombin III (AT III) and heparin cofactor II (HC II), and by inhibiting thrombin formation. Additionally, sulodexide enhances profibrinolytic activity by releasing tissue plasminogen activator (tPA). It also offers endothelial protection, possesses anti-inflammatory effects, and alleviates chronic venous disease.Colore e forma:SolidLMP7/LMP2-IN-1
CAS:LMP7/LMP2-IN-1 (Compound 19) is an orally effective inhibitor targeting the immunoproteasome subunits LMP7 and LMP2, with respective IC50 values of 257 and 10 nM. This compound reduces the production of antibodies and downregulates the B cells in the germinal centers of the spleen and plasma cells in NP-OVA immunized mice. It has potential applications in the study of autoimmune diseases.Formula:C16H27BN4O3Colore e forma:SoildPeso molecolare:334.22Chymotrypsinogen
CAS:Chymotrypsinogen is an inactive precursor of Chymotrypsin . Chymotrypsin is a serine protease produced by the pancreas [1] [2] .Colore e forma:SolidBictegravir Sodium
CAS:Bictegravir Sodium is an HIV-1 integrase inhibitor with 7.5 nM IC50, offering strong, selective anti-HIV effects and minimal toxicity.Formula:C21H17F3N3NaO5Purezza:99.97%Colore e forma:SolidPeso molecolare:471.36Sofosbuvir impurity L
Sofosbuvir impurity L is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.Formula:C22H29FN3O10PPurezza:98%Colore e forma:SolidPeso molecolare:545.45Phaeosphaone D
CAS:Phaeosphaone D, a thiodiketopiperazine from Phaeosphaeria fuckelii fungus, inhibits mushroom tyrosinase (IC50 = 33.2 μM).Formula:C20H27N3O3S2Colore e forma:SolidPeso molecolare:421.58MMP-3 Inhibitor
CAS:MMP-3 Inhibitor is a peptide matrix metalloproteinase-3 (MMP-3) inhibitor with a Ki value of 95 nM.MMP-3 inhibitor has anticancer and antitumor activity.Formula:C27H46N10O9SPurezza:98.87%Colore e forma:SolidPeso molecolare:686.78Ref: TM-T37048
1mg81,00€5mg208,00€10mg309,00€25mg525,00€50mg757,00€100mg1.035,00€500mg2.110,00€1mL*10mM (DMSO)221,00€HCV-IN-4
CAS:HCV-IN-4: Potent, oral HCV NS5A inhibitor; effective vs GT1a/b, GT2b, GT3a, Y93H, L31V; EC90s: 3 pM-0.02 nM.Formula:C52H58FN9O8Purezza:98%Colore e forma:SolidPeso molecolare:956.07Iso-VQA-ACC acetate
Iso-VQA-ACC acetate serves as a substrate for the constitutive proteasome.Colore e forma:Odour SolidDutogliptin tartrate
CAS:Dutogliptin tartrate is an effective and selective oral dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.Formula:C14H26BN3O9Purezza:98%Colore e forma:SolidPeso molecolare:391.18Sadopeptins B
Sadopeptins B, a natural product isolated from Streptomyces sp., is a potent proteasome inhibitor [1].Formula:C48H69N9O13SColore e forma:SolidPeso molecolare:1012.18NS5A-IN-1
NS5A-IN-1 is a proagent of the HCV NS5A inhibitor Pibrentasvir (ABT-530).Formula:C72H86F5N10O14PColore e forma:SolidPeso molecolare:1441.48JC-10
CAS:JC-10 is a potent inhibitor of metalloproteinases and is often used as a probe.Formula:C25H29Cl2IN4Purezza:95%Colore e forma:SolidPeso molecolare:583.34Sofigatran
CAS:Sofigatran (MCC-977) is an oral anticoagulant targeting thrombin for cardiovascular research.Formula:C24H44N4O4SColore e forma:SolidPeso molecolare:484.7Isoleucylvaline
CAS:Isoleucylvaline is a dipeptide.Formula:C11H22N2O3Colore e forma:SolidPeso molecolare:230.30Phosphorylase Kinase β-Subunit Fragment (420-436)
CAS:Phosphorylase Kinase β-Subunit Fragment (420-436) is a peptide fragment (430-436) derived from the β-Subunit of phosphorylase kinase.Formula:C79H131N31O25SPurezza:98%Colore e forma:SolidPeso molecolare:1947.14MMP-9-IN-7
CAS:N-[2-[(5-Cl-2-methoxyphenyl)amino]-4'-methyl[4,5'-bithiazol]-2'-yl]acetamide inhibits pro-MMP activation, treats MMP9/MMP13 syndromes.Formula:C16H15ClN4O2S2Purezza:97.65%Colore e forma:SolidPeso molecolare:394.9Ref: TM-T72069
1mg64,00€5mg131,00€10mg188,00€25mg325,00€50mg487,00€100mg708,00€500mg1.483,00€1mL*10mM (DMSO)131,00€FFAGLDD
"FFAGLDD: MMP9 peptide for controlled DOX delivery inside cells."Formula:C37H49N7O12Purezza:98%Colore e forma:SolidPeso molecolare:783.82PSI-7409
CAS:<p>PSI-7409 is the active 5'-triphosphate metabolite of Sofosbuvir (PSI-7977).</p>Formula:C10H16FN2O14P3Purezza:98%Colore e forma:SolidPeso molecolare:500.16Saxagliptin hydrochloride
CAS:Saxagliptin: oral DPP-4 inhibitor, enhances incretins, manages type 2 diabetes by reducing glucose levels.Formula:C18H26ClN3O2Colore e forma:SolidPeso molecolare:351.87Alogliptin (13CD3)
CAS:Alogliptin (SYR-322) 13CD3 is the deuterium-labeled Alogliptin. Alogliptin is a selective inhibitor of DPP-4.Formula:C18H21N5O2Purezza:98%Colore e forma:SolidPeso molecolare:343.4Tripeptide-32
CAS:Tripeptide-32 is a bioactive peptide recognized for its anti-aging properties, commonly utilized as an ingredient in cosmetics [1].Formula:C12H22N4O5Purezza:98%Colore e forma:SolidPeso molecolare:302.33E-64d [for Biochemical Research]
CAS:Formula:C17H30N2O5Purezza:>95.0%(HPLC)Colore e forma:White to Almost white powder to crystalPeso molecolare:342.44Ilomastat
CAS:Formula:C20H28N4O4Purezza:>95.0%(HPLC)(qNMR)Colore e forma:White to Light yellow powder to crystalPeso molecolare:388.47Thrombin inhibitor 5
CAS:Thrombin inhibitor 5 (compound 385), IC50: 0.1-1 μM, used in venous thromboembolism studies.Formula:C11H9FN4O3Purezza:99.58%Colore e forma:SolidPeso molecolare:264.21Ref: TM-T9845
2mg38,00€5mg59,00€10mg90,00€25mg162,00€50mg235,00€100mg339,00€200mg457,00€1mL*10mM (DMSO)58,00€CTS-1027
CAS:CTS-1027 is a small molecule inhibitor of MMPs (IC50s: 0.3 nM, 0.5 nM for MMP2, MMP13). It has > 1,000 fold selectivity over MMP1.Formula:C19H20ClNO6SColore e forma:SolidPeso molecolare:425.88Glutaminase-IN-3
CAS:Glutaminase-IN-3 is a potent Glutaminase 1 inhibitor with potential antitumor activity and inhibits GLS1 for cancer research.Formula:C19H19F3N6O2SPurezza:98.51%Colore e forma:SolidPeso molecolare:452.45Tenofovir hydrate
CAS:Tenofovir hydrate (GS 1278 hydrate) is a nucleotide reverse transcriptase inhibitor with antiviral activity.Formula:C9H16N5O5PPurezza:99.63%Colore e forma:SolidPeso molecolare:305.23Ubenimex Hydrochloride [for Biochemical Research]
CAS:Formula:C16H24N2O4·HClPurezza:>97.0%(HPLC)Colore e forma:White to Almost white powder to crystalPeso molecolare:344.84PSI-6206 13C,d3
CAS:<p>PSI-6206 13CD3 is the deuterium labeled PSI-6206. PSI-6206 is a potent and selective HCV NS5B polymerase inhibitor.</p>Formula:C10H13FN2O5Purezza:98%Colore e forma:SolidPeso molecolare:264.23LN5P45
LN5P45, an OTUB2 inhibitor (IC50: 2.3 μM), promotes monoubiquitination of OTUB2 at lysine 31 and is utilized in the study of tumor progression and metastasis [1Formula:C13H15ClN2O2Colore e forma:SolidPeso molecolare:266.726-Chloro-7-deazapurine-2F-β-D-arabinofuranose
CAS:6-Chloro-7-deazapurine-2F-β-D-arabinofuranose is a Nucleoside - 7-deazapurine nucleoside, fluoronucleoside, halo nucleoside; Arabino-nucleoside.Formula:C11H11ClFN3O3Colore e forma:SolidPeso molecolare:287.67Ref: TM-TNU0055
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiesta500mgPrezzo su richiestaDabigatran ethyl ester
CAS:Dabigatran ethyl ester (Dabigatran (ethyl ester)) is an emerging oral anticoagulant and it also is a direct inhibitor of thrombin activity.Formula:C27H29N7O3Purezza:99.98%Colore e forma:SolidPeso molecolare:499.56
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