Proteasi/Proteasoma
Gli inibitori delle proteasi e del proteasoma sono composti che bloccano l'attività delle proteasi e del proteasoma, che sono coinvolti nella degradazione e nel turnover delle proteine. Questi inibitori sono fondamentali per studiare la regolazione dell'omeostasi proteica, il controllo del ciclo cellulare e l'apoptosi. Gli inibitori delle proteasi e del proteasoma vengono anche utilizzati nel trattamento di malattie come il cancro, dove la degradazione anomala delle proteine svolge un ruolo nella progressione della malattia. Inibendo le proteasi o il proteasoma, questi composti possono indurre la morte cellulare nelle cellule tumorali e sono strumenti critici sia per la ricerca di base che per lo sviluppo terapeutico. Presso CymitQuimica, offriamo una vasta gamma di inibitori delle proteasi e del proteasoma di alta qualità per supportare la tua ricerca in biochimica, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Proteasi/Proteasoma"
- Acetil-CoA carbossilasi(50 prodotti)
- Cisteina proteasi(120 prodotti)
- DPP-4(27 prodotti)
- Glutaminasi(46 prodotti)
- Proteasi HIV(487 prodotti)
- PAI-1(30 prodotti)
- Inibitori della proteasi(49 prodotti)
- Ricettore attivato dalla proteasi(57 prodotti)
- Proteasoma(91 prodotti)
- Proteasi serina(70 prodotti)
- p97(15 prodotti)
Mostrare 3 più sottocategorie
Trovati 921 prodotti per "Proteasi/Proteasoma".
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KP-457
CAS:KP-457 is a ADAM17 and a TNFα converting enzyme TACE inhibitor that blocks the production of soluble TNF (sTNF).Formula:C21H24N2O7S2Purezza:98.33%Colore e forma:SolidPeso molecolare:480.56Ref: TM-T77778
1mg96,00€5mg205,00€1mL*10mM (DMSO)219,00€10mg334,00€25mg620,00€50mg982,00€100mg1.333,00€Danoprevir
CAS:Danoprevir (RG7227) is a peptidomimetic inhibitor of the NS3/4A protease(IC50=0.2-3.5 nM) of hepatitis C virus (HCV).Formula:C35H46FN5O9SPurezza:98% - 99.80%Colore e forma:Yellow SolidPeso molecolare:731.83PSI
CAS:PSI is a proteasome inhibitor.Formula:C32H50N4O8Purezza:97% - 98.33%Colore e forma:SolidPeso molecolare:618.76Triton X-45(n=4)
CAS:Triton X-45: nonionic, low HLB surfactant, dispersible in water, high Krafft point, relevant for HCV research.Formula:C22H38O5Colore e forma:SolidPeso molecolare:382.53KZR-504
CAS:KZR-504 is a selective inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2) (IC50s: 51 nM, 4.274 μM for LMP2 and LMP7, respectively).Formula:C21H23N3O6Colore e forma:SolidPeso molecolare:413.42Nelfinavir Mesylate
CAS:Formula:C32H45N3O4S·CH4O3SPurezza:>97.0%(HPLC)Colore e forma:White to Almost white powder to crystalPeso molecolare:663.89(-)-Gallocatechin Gallate
CAS:Formula:C22H18O11Purezza:>95.0%(HPLC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:458.38ALLM
CAS:ALLM (Calpain inhibitor II), a potent calpain and cathepsin protease inhibitor, not only prevents neuronal cell death but also enhances chronic neurological function following spinal cord injury (SCI)[1][2].Formula:C19H35N3O4SPurezza:98%Colore e forma:SolidPeso molecolare:401.56S 2160
CAS:S 2160 is a synthetic chromogenic substrate for thrombin.Formula:C33H40N8O6Colore e forma:SolidPeso molecolare:644.72HCV-IN-30
CAS:HCV-IN-30 is an HCV NS5A replication complex inhibitor (IC50s: 901 and 102 nM for genotypes 1a and 1b replicons).Formula:C36H44N6O4Purezza:99.6%Colore e forma:White SolidPeso molecolare:624.77AGG-523
CAS:AGG-523, an aggrecanase inhibitor, may slow cartilage wear after joint injury by reducing ARG-aggrecan in rats.Formula:C28H29FN2O4Colore e forma:SolidPeso molecolare:476.54NVP-DPP728 dihydrochloride
CAS:NVP-DPP728 dihydrochloride is a potent, selective DPP-IV inhibitor with a Ki of 11 nM, useful in diabetes research.Formula:C15H20Cl2N6OColore e forma:SolidPeso molecolare:371.27Carboxypeptidase G2 (CPG2) Inhibitor
CAS:Carboxypeptidase G2 (CPG2) Inhibitor (CPG2 Inhibitor) is a new CPG2 Inhibitor with antitumor activity.Formula:C13H15NO6SPurezza:99.96%Colore e forma:SolidPeso molecolare:313.33Cathepsin Inhibitor 1
CAS:Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.Formula:C20H24ClN5O2Purezza:99.78%Colore e forma:SolidPeso molecolare:401.89Ref: TM-T6015
1mg46,00€5mg90,00€1mL*10mM (DMSO)100,00€10mg144,00€25mg236,00€50mg371,00€100mg522,00€200mg743,00€Flovagatran
CAS:Flovagatran (TGN 255) is a potent, and selective inhibitor of thrombin and parenteral direct factor II.Flovagatran is used to study venous thromboembolism.Formula:C27H36BN3O7Purezza:99.56%Colore e forma:SolidPeso molecolare:525.4ER 27319 maleate
CAS:Selective inhibitor of Syk kinaseFormula:C22H24N2O5Purezza:98.45%Colore e forma:Yellow SolidPeso molecolare:396.44Diprotin B
CAS:Diprotin B is a dipeptidyl peptidase IV inhibitor.Formula:C16H29N3O4Purezza:98%Colore e forma:SolidPeso molecolare:327.42Tyrosinase-IN-4
CAS:Tyrosinase-IN-4, a potent inhibitor, has uses in skin-whitening, food preservation, cosmetics, agriculture, and medicine.Formula:C15H9ClO3Colore e forma:SolidPeso molecolare:272.68YD-3
CAS:YD-3 is a PAR4 antagonist that significantly inhibits thrombin-induced platelet aggregation in rabbits (IC(50)=28.3 microM). In addition, YD-3 suppresses thrombin-induced proliferation of vascular smooth muscle cells (VSMCs) and reduces neointimal thickening after balloon injury. Through Ras- and ERK1/2-mediated signaling pathways, YD-3 impedes thrombin-driven VSMC proliferation. When analyzed with Western blot, YD-3 primarily inhibits thrombin-induced expression of vascular endothelial growth factor receptor 2 (Flk-1) without affecting extracellular signal-regulated kinase 1/2 phosphorylation. YD-3 could potentially have value in elucidating the pathophysiology of thrombin-induced angiogenesis.Formula:C23H20N2O2Colore e forma:SolidPeso molecolare:356.42MyoMed 205
CAS:MyoMed-205 is an inhibitor of MuRF1 (muscle ring finger protein 1) activity. It effectively prevents early diaphragm contractile dysfunction and atrophy following 12 hours of unilateral phrenic nerve denervation. By inhibiting MuRF1, MyoMed-205 reduces muscle protein ubiquitination and subsequent proteasome degradation. It also increases the protein levels of phosphorylated Akt (ser473), an essential signaling molecule for muscle growth and maintenance. MyoMed-205 is applicable in the research and treatment of diaphragm dysfunction and atrophy (DIDD) due to early disuse, particularly in clinical situations such as diaphragm paralysis or mechanical ventilation.Formula:C26H25N3O5SColore e forma:SolidPeso molecolare:491.56
