CymitQuimica logo
Proteasi/Proteasoma

Proteasi/Proteasoma

Gli inibitori delle proteasi e del proteasoma sono composti che bloccano l'attività delle proteasi e del proteasoma, che sono coinvolti nella degradazione e nel turnover delle proteine. Questi inibitori sono fondamentali per studiare la regolazione dell'omeostasi proteica, il controllo del ciclo cellulare e l'apoptosi. Gli inibitori delle proteasi e del proteasoma vengono anche utilizzati nel trattamento di malattie come il cancro, dove la degradazione anomala delle proteine svolge un ruolo nella progressione della malattia. Inibendo le proteasi o il proteasoma, questi composti possono indurre la morte cellulare nelle cellule tumorali e sono strumenti critici sia per la ricerca di base che per lo sviluppo terapeutico. Presso CymitQuimica, offriamo una vasta gamma di inibitori delle proteasi e del proteasoma di alta qualità per supportare la tua ricerca in biochimica, biologia cellulare e sviluppo di farmaci.

Sottocategorie di "Proteasi/Proteasoma"

Mostrare 3 più sottocategorie

Trovati 1094 prodotti di "Proteasi/Proteasoma"

Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
prodotti per pagina.
  • VA4 TG2 inhibitor
    Targetmol
    + Info

    VA4 TG2 inhibitor

    CAS:
    VA4 is a novel irreversible TG2 transamidase site-specific inhibitor.
    Formula:C33H41N5O6S
    Colore e forma:Solid
    Peso molecolare:635.77

    Ref: TM-T69933

  • AZD5248
    Targetmol
    + Info

    AZD5248

    CAS:
    AZD-5248 is a potent, selective, first generation, oral inhibitor of dipeptidyl peptidase 1 (DPP1).
    Formula:C22H22N4O2
    Colore e forma:Solid
    Peso molecolare:374.44

    Ref: TM-T71117

  • Lodelaben
    Targetmol
    + Info

    Lodelaben

    CAS:
    Lodelaben (Declaben, SC-39026) is a reversible, non-competitive,specific inhibitor of human neutrophil elastase (HNE) with high potency (IC50=0.5 μM).
    Formula:C25H41ClO3
    Purezza:99.62% - >99.99%
    Colore e forma:Solid
    Peso molecolare:425.04

    Ref: TM-T11865

  • BMS-363131
    Targetmol
    + Info

    BMS-363131

    CAS:
    BMS-363131 (BMS363131) is a potent and selective trypsin inhibitor with an IC50 value of <1.7 nM.
    Formula:C28H40N6O5
    Purezza:97.99%
    Colore e forma:Solid
    Peso molecolare:540.65

    Ref: TM-T30519

  • p-APMSF (hydrochloride)
    Targetmol
    + Info

    p-APMSF (hydrochloride)

    CAS:
    p-APMSF irreversibly inhibits several serine proteases; Ki: 1.02-1.54 μM; selective over chymotrypsin and acetylcholinesterase.
    Formula:C8H10ClFN2O2S
    Colore e forma:Solid
    Peso molecolare:252.69

    Ref: TM-T37019

  • α-Glucosidase-IN-5
    Targetmol
    + Info

    α-Glucosidase-IN-5

    CAS:
    α-Glucosidase-IN-5 (compound 8) is isolated from a twig extract of Polyalthia cinnamomea which is a potent α-glucosidase inhibitor with an IC50 of 57.9 µM.
    Formula:C15H13NO3
    Colore e forma:Solid
    Peso molecolare:255.27

    Ref: TM-T60389

  • p-Aminobenzamidine dihydrochloride
    Targetmol
    + Info

    p-Aminobenzamidine dihydrochloride

    CAS:
    <p>4-Aminobenzamidine dihydrochloride (p-Aminobenzamidine dihydrochloride) is a strong trypsin inhibitor and a relatively weak inhibitor of urokinase type</p>
    Formula:C7H11Cl2N3
    Purezza:99.00% - 99.56%
    Colore e forma:Solid
    Peso molecolare:208.088

    Ref: TM-T60248

  • SAP2-IN-1
    Targetmol
    + Info

    SAP2-IN-1

    CAS:
    SAP2-IN-1 inhibits secreted aspartate protease 2 (IC50: 0.92 μM), doesn't work in vitro, and helps research infections.
    Formula:C34H29NO7
    Colore e forma:Solid
    Peso molecolare:563.6

    Ref: TM-T63986

  • MK-2048
    Targetmol
    + Info

    MK-2048

    CAS:
    <p>MK-2048 is a potent inhibitor of integrase (IN) and INR263K with IC50 of 2.6 nM and 1.5 nM, respectively.</p>
    Formula:C21H21ClFN5O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:461.87

    Ref: TM-T6589

  • PF-06279794
    Targetmol
    + Info

    PF-06279794

    CAS:
    PF-06279794 is a potent, selective and ATP-competitive TNIK inhibitor.
    Formula:C22H20N4O
    Colore e forma:Solid
    Peso molecolare:356.42

    Ref: TM-T28370

  • Glutaminase-IN-4
    Targetmol
    + Info

    Glutaminase-IN-4

    CAS:
    <p>Glutaminase-IN-4 (compound 2a) is a glutaminase (GLS) inhibitor (IC50: 2.3 μM).</p>
    Formula:C23H22N6O2S2
    Colore e forma:Solid
    Peso molecolare:478.59

    Ref: TM-T63137

  • L 658758
    Targetmol
    + Info

    L 658758

    CAS:
    L 658758 is an inhibitor of serine proteinase.
    Formula:C16H20N2O9S
    Colore e forma:Solid
    Peso molecolare:416.4

    Ref: TM-T24311

  • (S)-BI-1001
    Targetmol
    + Info

    (S)-BI-1001

    CAS:
    (S)-BI-1001 is an active S-enantiomer of BI-1001. (S)-BI-1001 has antiviral potency against HIV-1 integrase (IC50: 28 nM, and EC50: 450 nM and a Kd: 4.7 μM).
    Formula:C19H15BrClNO3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:420.68

    Ref: TM-T16829

  • AZD-1236
    Targetmol
    + Info

    AZD-1236

    CAS:
    AZD1236 is a selective inhibitor for human MMP-9/MMP-12, less effective in rodents, and reduces lung injury and inflammation.
    Formula:C15H19ClN4O5S
    Colore e forma:Solid
    Peso molecolare:402.85

    Ref: TM-T69230

  • MMP13-IN-4
    Targetmol
    + Info

    MMP13-IN-4

    CAS:
    MMP13-IN-4 (compound 13) is a potent, selective MMP-13 inhibitor with an IC50 of 14.6 μM, implicated in the pathology of osteoarthritis (OA) [1].
    Formula:C21H17BrN4O5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:485.29

    Ref: TM-T78774

  • Butabindide
    Targetmol
    + Info

    Butabindide

    CAS:
    Butabindide (UCL-1397) selectively inhibits TPP II, protecting CCK-8, with Ki of 10 μM (TPP I) and 7 nM (TPP II).
    Formula:C17H25N3O2
    Colore e forma:Solid
    Peso molecolare:303.4

    Ref: TM-T60700

  • CP4d inhibitor
    Targetmol
    + Info

    CP4d inhibitor

    CAS:
    CP4d is a novel reversible tg2 transamidase site-specific inhibitor
    Formula:C18H13N5O5
    Colore e forma:Solid
    Peso molecolare:379.33

    Ref: TM-T71477

  • BC-23
    Targetmol
    + Info

    BC-23

    CAS:
    BC-23 (NSC 45382) is a proteasome inhibitor with antitumor and antimicrobial activity for the study of leukemia and small cell lung cancer.
    Formula:C21H14ClN3O4S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:439.87

    Ref: TM-T26754

  • Z-LLF-CHO
    Targetmol
    + Info

    Z-LLF-CHO

    CAS:
    <p>Z-LLF-CHO (Z-Leu-Leu-Phe-CHO) effectively inhibits the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex with a Ki value of 460 nM.</p>
    Formula:C29H39N3O5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:509.64

    Ref: TM-T78640

  • BR351
    Targetmol
    + Info

    BR351

    CAS:
    BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).
    Formula:C20H25FN2O5S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:424.49

    Ref: TM-T10597