Cellule staminali e Derivati
Gli inibitori delle cellule staminali sono composti che bersagliano specificamente le vie di segnalazione e le proteine coinvolte nel mantenimento, nella differenziazione e nella proliferazione delle cellule staminali. Questi inibitori sono cruciali per comprendere la biologia delle cellule staminali e per sviluppare strategie per manipolare le cellule staminali a fini terapeutici, come la medicina rigenerativa e il trattamento del cancro. Controllando il destino delle cellule staminali, questi inibitori possono aiutare a guidare la differenziazione delle cellule staminali in tipi cellulari specifici o a prevenire una crescita cellulare indesiderata. Presso CymitQuimica, offriamo una selezione di inibitori delle cellule staminali di alta qualità per supportare la tua ricerca in biologia delle cellule staminali, biologia dello sviluppo e medicina rigenerativa.
Sottocategorie di "Cellule staminali e Derivati"
- Gamma-secretasi(62 prodotti)
- Proteina Hedgehog/Smoothened(49 prodotti)
- Via di segnalazione Hippo(7 prodotti)
- JAK(247 prodotti)
- Proteina Porcupine(9 prodotti)
- ROCK(66 prodotti)
- STAT(97 prodotti)
- Cellule staminali(460 prodotti)
- TGF-beta/Smad(60 prodotti)
- Wnt/beta-catenina(63 prodotti)
Mostrare 2 più sottocategorie
Trovati 679 prodotti di "Cellule staminali e Derivati"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
JAK-IN-1
CAS:JAK-IN-1 shows improved selectivity for JAK3 over JAK1. JAK-IN-1 is a JAK1/2/3 inhibitor with IC50s of 0.26, 0.8 and 3.2 nM, respectively.Formula:C20H24N6O2Purezza:98%Colore e forma:SolidPeso molecolare:380.44BMS-983970
CAS:BMS-983970 is an oral inhibitor of pan-Notch, and for the treatment of multiplecancers.Formula:C26H26F4N4O3Colore e forma:SolidPeso molecolare:518.5Tubulin/JAK2-IN-1
CAS:Tubulin/JAK2-IN-1 (compound 7g) serves as a potent dual inhibitor targeting both Janus kinase 2 (JAK2) and microtubules, demonstrating significantFormula:C22H20N6O3Colore e forma:SolidPeso molecolare:416.43Yhhu-3792 hydrochloride
CAS:Yhhu-3792 hydrochloride is a compound that bolsters the self-renewal capacity of neural stem cells (NSCs), catalyzes the Notch signaling pathway, and upregulates expression of Hes3 and Hes5. It augments the NSC pool, stimulates endogenous neurogenesis in the mouse hippocampal dentate gyrus (DG), and enhances mice's spatial and episodic memory skills. This compound shows promise for researching learning and memory impairments linked to DG dysfunction [1].Formula:C24H25ClN4O2Colore e forma:SolidPeso molecolare:436.93JAK-IN-3
CAS:JAK-IN-3 is a potent JAK inhibitor that inhibits JAK3, JAK1, TYK2, and JAK2, and can be used for the study of immune system disorders.Formula:C18H20N4O3Purezza:98.04% - 98.19%Colore e forma:SolidPeso molecolare:340.38ROCK-IN-1
CAS:ROCK-IN-1 is a potent ROCK inhibitor that inhibits ROCK2-mediated signaling with an IC50 value of 1.2 nM.ROCK-IN-1 can be used in the study of neurologicalFormula:C20H18FN3OPurezza:>99.99%Colore e forma:SolidPeso molecolare:335.37H-1152 dihydrochloride
CAS:H-1152 2HCl: ROCK inhibitor, IC50=12 nM, Ki=1.6 nM. Blocks PKA, PKC, PKG, Aurora A, CaMKII with higher IC50s.Formula:C16H23Cl2N3O2SPurezza:99.85%Colore e forma:SolidPeso molecolare:392.34GNE-7883
CAS:GNE-7883 is an inhibitor targeting TEAD transcription factor, inhibits cell proliferation and suppresses YAP/TAZ activation, and can be used to study YAP/TAZ-dependent tumors.Formula:C28H29FN6O2Purezza:97.61%Colore e forma:SolidPeso molecolare:500.57STAT6-IN-2
CAS:STAT6-IN-2(R)-84 is a STAT6 inhibitor that inhibits the secretion of eotaxin-3 and the tyrosine phosphorylation of STAT6.Formula:C28H31N5O2Purezza:99.67%Colore e forma:SolidPeso molecolare:469.58GSK-3 inhibitor 1
CAS:GSK-3 inhibitor 1 is a GSK-3 inhibitor.Formula:C22H17ClFN5O2Purezza:98.42%Colore e forma:SolidPeso molecolare:437.85(3S,4R)-Tofacitinib
CAS:(3S,4R)-Tofacitinib is an less active enantiomer of Tofacitinib. Tofacitinib is a JAK3 inhibitor(IC50 : 1 nM).Formula:C16H20N6OPurezza:98%Colore e forma:SolidPeso molecolare:312.37CDK8-IN-11
CAS:CDK8-IN-11 is a CDK8 inhibitor that demonstrates anti-proliferative activity against colon cancer cell lines and inhibits the activation of WNT/β-catenin.Formula:C19H15F3N4O2Purezza:99.74%Colore e forma:SolidPeso molecolare:388.34TEAD-IN-1
CAS:<p>TEAD-IN-1 (Compound 2) is an effective inhibitor of TEAD auto-palmitoylation with an IC50 of 603 nM. It enhances the interaction between TEAD and VGLL4, while diminishing the interaction between YAP and TEAD. TEAD-IN-1 is applicable for cancer research.</p>Formula:C15H20F2N2O3SColore e forma:SolidPeso molecolare:346.393JAK1/TYK2-IN-3
JAK1/TYK2-IN-3, orally active, selectively inhibits TYK2 (IC50: 6 nM), JAK1 (37 nM), JAK2 (140 nM), JAK3 (362 nM), and has anti-inflammatory effects.Colore e forma:SolidSTAT3-IN-8
CAS:"STAT3-IN-8 (compound H172) is a potent inhibitor of STAT3 with potential applications in cancer research [1]."Formula:C19H7F7N2O3Purezza:98%Colore e forma:SolidPeso molecolare:444.26lirucitinib
CAS:<p>Lirucitinib is a JAK inhibitor known for its anti-inflammatory properties.</p>Formula:C16H25N5OSColore e forma:SolidPeso molecolare:335.468JAK3-IN-11
CAS:JAK3-IN-11: potent oral JAK3 inhibitor (IC50=1.7 nM), noncytotoxic, >588-fold selectivity, blocks T-cell growth; useful in autoimmune research.Formula:C23H23N5O2Colore e forma:SolidPeso molecolare:401.46(+)-ITD-1
CAS:(+)-ITD-1 is an inhibitor of TGF-β, effectively inhibiting TGF-β2 with an IC50 of 0.46 μM. It promotes the degradation of the TGF-β type II receptor (TGFBR2) and the differentiation of cardiomyocytes. Additionally, it suppresses the formation of the mesoderm during the early differentiation of mouse embryonic stem cells (mESCs).Formula:C27H29NO3Colore e forma:SolidPeso molecolare:415.52CEE321
CAS:CEE321 is an effective pan-JAK inhibitor with an IC50 of 54 nM. It effectively inhibits biomarkers associated with atopic dermatitis.Formula:C18H16ClN5OColore e forma:SolidPeso molecolare:353.806Tyk2-IN-3
CAS:Tyk2-IN-3 is an inhibitor of Tyk2 pseudokinase (IC50: 485 nM).Formula:C25H24N6O3S2Purezza:98%Colore e forma:SolidPeso molecolare:520.63
