Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1473 prodotti di "Autofagia"
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Silmitasertib sodium salt
CAS:Silmitasertib sodium salt (CX-4945 sodium salt) is a potent and orally bioavailable, highly selective inhibitor of CK2(IC50 of 1 nM, CK2α).Formula:C19H11ClN3NaO2Purezza:99.49% - 99.62%Colore e forma:SolidPeso molecolare:371.75Pravastatin sodium
CAS:Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.Formula:C23H35NaO7Purezza:97.14% - 99.97%Colore e forma:White Crystalline PowderPeso molecolare:446.52NBDHEX
CAS:NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1).Formula:C12H15N3O4SPurezza:97.38%Colore e forma:SolidPeso molecolare:297.33Sunitinib Malate
CAS:<p>Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor.</p>Formula:C26H33FN4O7Purezza:98% - 99.26%Colore e forma:SolidPeso molecolare:532.56Matrine
CAS:<p>Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.</p>Formula:C15H24N2OPurezza:97.16% - >99.99%Colore e forma:SolidPeso molecolare:248.36Paclitaxel
CAS:<p>Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer.</p>Formula:C47H51NO14Purezza:98% - 99.92%Colore e forma:White PowderPeso molecolare:853.91Crustecdysone
CAS:<p>Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.</p>Formula:C27H44O7Purezza:99.06% - 99.67%Colore e forma:Canary Yellow Fine PowderPeso molecolare:480.63Nicardipine hydrochloride
CAS:<p>Nicardipine hydrochloride is a potent calcium channel blocker used to dilate cerebral and coronary vessels.</p>Formula:C26H30ClN3O6Purezza:99.58% - 99.89%Colore e forma:Yellow SolidPeso molecolare:515.99BIX 02565
CAS:BIX 02565 is a potent inhibitor of ribosomal S6 kinase 2 (RSK2, IC50: 1.1 nM).Formula:C26H30N6O2Purezza:97.44% - 99.7%Colore e forma:SolidPeso molecolare:458.56Oxaliplatin
CAS:Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis.Formula:C8H14N2O4PtPurezza:97% - 99.93%Colore e forma:SolidPeso molecolare:397.29Colistin sulfate
CAS:<p>Colistin sulfate (Colistin sulfate (1066-17-7 free base)) is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.</p>Formula:C53H100N16O17SPurezza:98%Colore e forma:PowderPeso molecolare:1253.51Irinotecan Hydrochloride
CAS:<p>Irinotecan HCl, a camptothecin derivative prodrug, becomes active metabolite SN-38, inhibiting topoisomerase I to trigger apoptosis.</p>Formula:C33H39ClN4O6Purezza:98% - 99.94%Colore e forma:Yellow Crystalline PowderPeso molecolare:623.14Lomustine
CAS:Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors.Formula:C9H16ClN3O2Purezza:98.36% - 99.44%Colore e forma:Solid SolidPeso molecolare:233.7Itraconazole
CAS:Itraconazole (R51211) is a triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.Formula:C35H38Cl2N8O4Purezza:98% - 99.90%Colore e forma:Off-White Crystalline SolidPeso molecolare:705.63Phenformin hydrochloride
CAS:Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.Formula:C10H16ClN5Purezza:97.11% - 99.80%Colore e forma:Lactic AcidosisPeso molecolare:241.72Memantine hydrochloride
CAS:<p>Memantine hydrochloride (Memantine HCl) is an AMANTADINE derivative that has some dopaminergic effects.</p>Formula:C12H22ClNPurezza:99.56% - 99.96%Colore e forma:Crystalline SolidPeso molecolare:215.76Oxidopamine hydrobromide
CAS:<p>Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.</p>Formula:C8H12BrNO3Purezza:98.22% - 99.88%Colore e forma:Beige To Brown Fine Crystalline PowderPeso molecolare:250.09Doxorubicin hydrochloride
CAS:Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).Formula:C27H29NO11·HClPurezza:98% - 99.52%Colore e forma:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Peso molecolare:579.99Glibenclamide
CAS:<p>Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.</p>Formula:C23H28ClN3O5SPurezza:99.05% - 99.75%Colore e forma:SolidPeso molecolare:494.00Fluvastatin sodium
CAS:Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterolFormula:C24H25FNNaO4Purezza:98.54% - 99.56%Colore e forma:Light Yellow Solid PowderPeso molecolare:433.45Erlotinib
CAS:Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.Formula:C22H23N3O4Purezza:98.19% - 99.98%Colore e forma:White To Off-White PowderPeso molecolare:393.44AZD7624
CAS:AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.Formula:C27H30FN5O3Purezza:98.82%Colore e forma:SolidPeso molecolare:491.56Reserpine
CAS:<p>Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.</p>Formula:C33H40N2O9Purezza:98.85% - 99.81%Colore e forma:White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)Peso molecolare:608.68ZX-29
CAS:ZX-29: Strong ALK inhibitor; IC50 - ALK 2.1 nM, L1196M 1.3 nM, G1202R 3.9 nM; triggers autophagy; anti-cancer.Formula:C23H28ClN7O3SPurezza:98.32%Colore e forma:SolidPeso molecolare:518.03Carboplatin
CAS:<p>Carboplatin (JM-8) is a cisplatin derivative, a DNA synthesis inhibitor.</p>Formula:C6H12N2O4PtPurezza:98% - 99.72%Colore e forma:White Crystalline PowderPeso molecolare:371.25Vancomycin hydrochloride
CAS:Vancomycin hydrochloride (Vancomycin HCl) targets peptidoglycan in bacterial cell wall synthesis. High-Quality, Low-Cost!Formula:C66H76Cl3N9O24Purezza:97.20% - 99.19%Colore e forma:Off White PowderPeso molecolare:1485.71Raloxifene hydrochloride
CAS:Raloxifene HCl treats postmenopausal osteoporosis, acts as estrogen on bone/cholesterol, and blocks it in breast/uterus.Formula:C28H28ClNO4SPurezza:98% - 99.97%Colore e forma:Light Yellow SolidPeso molecolare:510.044LG-100064
CAS:LG-100064 is an agonist of retinoid-X-receptor (RXR)(EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ)Formula:C23H26O3Purezza:98.65%Colore e forma:SolidPeso molecolare:350.45Pyrazinamide
CAS:Pyrazinamide (Pyrazinecarboxamide), an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amideFormula:C5H5N3OPurezza:99.71% - 99.9%Colore e forma:Crystals Physical Description White Powder Sublimes From 318°F (Ntp 1992)Peso molecolare:123.11Amiodarone hydrochloride
CAS:<p>Amiodarone HCl: Antianginal, class III antiarrhythmic. Lengthens heart muscle action, slows heart rate, reduces vascular resistance.</p>Formula:C25H29I2NO3·HClPurezza:99.82% - ≥95%Colore e forma:White To Cream Crystalline PowderPeso molecolare:681.78Dexamethasone
CAS:Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.Formula:C22H29FO5Purezza:98% - 99.91%Colore e forma:Crystals From Ether (Ntp 1992)Peso molecolare:392.46Avermectin B1
CAS:Avermectin B1 is served as anthelmintic and insecticide.Formula:C48H72O14Purezza:mixture - mixtureColore e forma:White PowderPeso molecolare:873.09Mevastatin
CAS:Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum.Formula:C23H34O5Purezza:99.12%Colore e forma:White-Yellowish To Yellow Powder Solid PowderPeso molecolare:390.51Cytarabine
CAS:Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM).Formula:C9H13N3O5Purezza:99.83% - 99.93%Colore e forma:Fine Off-White Crystalline PowderPeso molecolare:243.22Thalidomide
CAS:Thalidomide, a glutamic acid derivative, has teratogenic and immunomodulatory effects.Formula:C13H10N2O4Purezza:98.88% - 99.88%Colore e forma:White SolidPeso molecolare:258.23Doxazosin mesylate
CAS:Doxazosin mesylate (UK 33274 mesylate)(UK 33274) is a quinazoline-derivative. It is a selectively antagonizes postsynaptic α1-adrenergic receptors.Formula:C24H29N5O8SPurezza:99.92%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:547.58Trimetazidine dihydrochloride
CAS:Trimetazidine, an anti-ischemic agent, enhances myocardial glucose use, inhibits fat metabolism, and helps with angina.Formula:C14H24Cl2N2O3Purezza:99.58%Colore e forma:Crystalline SolidPeso molecolare:339.258Pictilisib dimethanesulfonate
CAS:Pictilisib dimethanesulfonate (GDC-0941 2 MeSO3H salt) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) andFormula:C25H35N7O9S4Purezza:99.63%Colore e forma:SolidPeso molecolare:705.85Ketanserin
CAS:Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.Formula:C22H22FN3O3Purezza:99.19% - 99.73%Colore e forma:SolidPeso molecolare:395.43Hydroxyurea
CAS:Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.Formula:CH4N2O2Purezza:99.85% - 99.92%Colore e forma:SolidPeso molecolare:76.05MLi-2
CAS:MLi-2: Novel, potent CNS-active LRRK2 inhibitor; IC50s: 0.76nM in vitro, 1.4nM cellular, 3.4nM binding.Formula:C21H25N5O2Purezza:98.96%Colore e forma:SolidPeso molecolare:379.46Lapatinib Ditosylate
CAS:Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).Formula:C29H26ClFN4O4S·2C7H8O3SPurezza:99.41%Colore e forma:Yellow SolidPeso molecolare:925.46Dihydroartemisinin
CAS:Dihydroartemisinin (Artenimol) is an antimalarial drug. High-Quality, Low-Cost!Formula:C15H24O5Purezza:98% - 99.41%Colore e forma:White SolidPeso molecolare:284.35Lapatinib ditosylate monohydrate
CAS:<p>Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.</p>Formula:C29H26ClFN4O4S·2(C7H8O3S)·H2OPurezza:98% - 99.41%Colore e forma:Colourless To Light-Yellow CrystalPeso molecolare:943.47Sophocarpine monohydrate
CAS:Sophocarpine monohydrate, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.Formula:C15H22N2OPurezza:99.55%Colore e forma:SolidPeso molecolare:246.35Dexamethasone acetate
CAS:<p>Dexamethasone acetate (NSC 39471) is a potent anti-inflammatory steroid, blocks NF-kB, and lacks salt-retention.</p>Formula:C24H31FO6Purezza:99.22% - 99.65%Colore e forma:White Or Almost White Crystalline PowderPeso molecolare:434.50Spironolactone
CAS:Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.Formula:C24H32O4SPurezza:99.87%Colore e forma:White PowderPeso molecolare:416.57Chenodeoxycholic acid
CAS:<p>Chenodeoxycholic acid (CDCA) is a bile acid that inhibits 11β-HSD2 with an IC50 value of 22 mM. High-Quality, Low-Cost!</p>Formula:C24H40O4Purezza:99.70% - 99.93%Colore e forma:White - Almost White Solid PowderPeso molecolare:392.57TTNPB
CAS:TTNPB (Ro 13-7410,AGN-191183), a potent RAR agonist, inhibits binding of [3H]tRA of human RARα (IC50: 5.1 nM), β (IC50: 4.5 nM), and γ (IC50: 9.3 nM),Formula:C24H28O2Purezza:99.55%Colore e forma:White SolidPeso molecolare:348.48Naringin
CAS:Naringin: flavanone glycoside with blood lipid-reducing, antioxidant, anticancer properties, inhibits cytochrome P450.Formula:C27H32O14Purezza:99.23%Colore e forma:Beige Creamish Powder Solid Solid Particulate/PowderPeso molecolare:580.53
