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Proteina G/GPCR

Proteina G/GPCR

Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.

Sottocategorie di "Proteina G/GPCR"

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Trovati 5378 prodotti di "Proteina G/GPCR"

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  • Logo CymitQuimica
    Targetmol
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    MrgprX2 antagonist-6

    <p>MrgprX2 antagonist-6 is a potent antiallergic agent with inhibitory effects on mast cell degranulation.</p>
    Formula:C24H23F3N6O3
    Colore e forma:Solid
    Peso molecolare:500.47

    Ref: TM-T63394

  • Aeruginosin 98-B
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    Aeruginosin 98-B

    CAS:
    <p>Aeruginosin 98-B, a protease inhibitor, effectively inhibits trypsin, plasmin, and thrombin with IC50 values of 0.6, 7.0, and 10.0 μg/mL, respectively.</p>
    Formula:C29H46N6O9S
    Colore e forma:Solid
    Peso molecolare:654.78

    Ref: TM-T72736

  • Alixorexton
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    Alixorexton

    CAS:
    <p>Alixorexton is an agonist of the orexin-2 receptor (orexin-2 receptor) and is utilized in obesity research.</p>
    Formula:C21H30N2O5S
    Colore e forma:Solid
    Peso molecolare:422.538

    Ref: TM-T205053

  • (-)-5-HT2C agonist-3
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    (-)-5-HT2C agonist-3

    CAS:
    <p>Compound (−)-19, also known as (-)-5-HT2C agonist-3, is a selective 5-HT2C agonist exhibiting a preference for Gq signaling. It demonstrates efficiency with EC50 values for 5-HT2 receptor subtypes as follows: 5-HT2C at 103 nM, 5-HT2B at 570 nM, and 5-HT2A at 72 nM. This compound is utilized in research on antipsychotics.</p>
    Formula:C19H23ClFNO2
    Colore e forma:Solid
    Peso molecolare:351.84

    Ref: TM-T200458

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    Dopamine D3 receptor ligand-1

    <p>Dopamine D 3 receptor ligand is a potent, selective, high-affinity dopamine D3 receptor ligand that is 89 times more selective for D3 (Ki: 8 nM) than D2 (Ki:</p>
    Formula:C27H29N5O
    Colore e forma:Solid
    Peso molecolare:439.55

    Ref: TM-T62528

  • AAZ-A 154 hydrobromide
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    AAZ-A 154 hydrobromide

    CAS:
    <p>AAZ-A 154 hydrobromide is a selective, competitive, non-hallucinogenic 5-HT2AR antagonist. It promotes neuronal growth in rodents and yields enduring beneficial behavioral effects.</p>
    Formula:C14H21BrN2O
    Colore e forma:Solid
    Peso molecolare:313.23

    Ref: TM-T200446

  • Nifeviroc
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    Nifeviroc

    CAS:
    <p>Nifeviroc (TD-0232) is an orally active CCR5 antagonist, useful in HIV-1 infection research.</p>
    Formula:C33H42N4O6
    Purezza:98.14%
    Colore e forma:Solid
    Peso molecolare:590.71

    Ref: TM-T28171

  • PD 140376
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    PD 140376

    CAS:
    <p>PD 140376: Selective CCK-B/gastrin receptor antagonist radioligand for guinea pig stomach &amp; brain.</p>
    Formula:C33H40N4O5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:572.69

    Ref: TM-T28335

  • SAR-114137
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    SAR-114137

    CAS:
    <p>SAR-114137 is a histone sphingomyelin kinase inhibitor used in the study of molluscum arteriosum and peripheral neuropathic pain.</p>
    Formula:C25H34N4O7S
    Purezza:99.09% - 99.91%
    Colore e forma:Solid
    Peso molecolare:534.63

    Ref: TM-T28658

  • CHF-6366
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    CHF-6366

    CAS:
    <p>CHF-6366: M3 antagonist &amp; β2 agonist (pKi 10.4/11.4), mild Ca channel blocker, used in COPD study.</p>
    Formula:C42H48N6O8
    Colore e forma:Solid
    Peso molecolare:764.87

    Ref: TM-T70376

  • Logo CymitQuimica
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    AM8936

    <p>AM8936: potent CB1 agonist, EC50 rCB1=8.6nM/hCB1=1.4nM, Ki rat CB1=0.55nM; potential for CNS, metabolic, pain, glaucoma research.</p>
    Formula:C25H33NO3
    Colore e forma:Solid
    Peso molecolare:395.53

    Ref: TM-T61849

  • BAY-3153
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    BAY-3153

    CAS:
    <p>BAY-3153 is a selective CCR1 ( C-C motif chemokine receptor 1 ) antagonist (human IC 50 =3 nM ; rat IC 50 =11 nM ; mice IC 50 =81 nM) .</p>
    Formula:C25H29Cl2N3O4
    Colore e forma:Solid
    Peso molecolare:506.42

    Ref: TM-T73371

  • PF-07054894
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    PF-07054894

    CAS:
    <p>PF-07054894: potent CCR6 antagonist, targets GPCR, for inflammatory bowel disease research.</p>
    Formula:C24H30N6O4
    Colore e forma:Solid
    Peso molecolare:466.53

    Ref: TM-T73005

  • Logo CymitQuimica
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    Protease-Activated Receptor-1 antagonist 1

    <p>Compound 13 is a PAR-1 antagonist with a 3 nM IC50, useful for thrombosis and heart disease research.</p>
    Formula:C25H24F2N2O3
    Colore e forma:Solid
    Peso molecolare:438.47

    Ref: TM-T62507

  • GLP-1 receptor agonist 16
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    GLP-1 receptor agonist 16

    CAS:
    <p>GLP-1 receptoragonist 16 (Example 53) is a GLP-1 agonist applicable for research in diabetes, obesity, or diseases related to non-alcoholic steatohepatitis.</p>
    Formula:C33H31ClFN3O4
    Colore e forma:Solid
    Peso molecolare:588.068

    Ref: TM-T204526

  • L-657926
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    L-657926

    CAS:
    <p>L-657926 is a stereoselective antagonist of the thromboxane A2 (TxA2) receptor, composed of (-)-9-chlorobenzyl-6-fluoro-1,2,3,4-tetrahydrocarbazol-1-yl acetic acid and (+)-9-chlorobenzyl-6-fluoro-1,2,3,4-tetrahydrocarbazol-1-yl acetic acid. The IC50 values for the (-) and (+) configurations against TxA2 are 0.27 nM and 124 nM, respectively.</p>
    Formula:C21H19ClFNO2
    Colore e forma:Solid
    Peso molecolare:371.832

    Ref: TM-T204805

  • LB-102
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    LB-102

    CAS:
    <p>LB-102 is an orally active inhibitor of dopamine D2, D3, and serotonin 5-HT7 receptors, utilized in the study of schizophrenia and other psychiatric disorders.</p>
    Formula:C18H29N3O4S
    Colore e forma:Solid
    Peso molecolare:383.51

    Ref: TM-T200914

  • BD-1047
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    BD-1047

    CAS:
    <p>BD-1047 is a selective functional antagonist of sigma receptors. It can alleviate climbing behavior induced by Apomorphine and head twitching caused by Phencyclidine.</p>
    Formula:C13H20Cl2N2
    Colore e forma:Solid
    Peso molecolare:275.217

    Ref: TM-T205677

  • Taranabant
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    Taranabant

    CAS:
    <p>Taranabant: potent CB1 receptor inverse agonist; inhibits agonists with 0.13 nM Ki in vitro.</p>
    Formula:C27H25ClF3N3O2
    Purezza:99.06% - 99.06%
    Colore e forma:Solid
    Peso molecolare:515.96

    Ref: TM-T13080L

  • Logo CymitQuimica
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    (R)-MrgprX2 antagonist-3

    CAS:
    <p>(R)-MrgprX2 antagonist-3 is an antagonist of MrgprX2. It is applicable in the study of inflammatory skin diseases. For more detailed information, please refer to compound E118 in patent document WO2021092240A1.</p>
    Formula:C16H20FN3O2S
    Peso molecolare:337.41

    Ref: TM-T208997