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Proteina G/GPCR

Proteina G/GPCR

Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.

Sottocategorie di "Proteina G/GPCR"

Mostrare 18 più sottocategorie

Trovati 5352 prodotti di "Proteina G/GPCR"

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  • Bzo-poxizid
    Targetmol
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    Bzo-poxizid

    CAS:
    <p>Bzo-poxizid is a synthetic cannabinoid and a psychoactive substance.</p>
    Formula:C20H21N3O2
    Colore e forma:Solid
    Peso molecolare:335.40

    Ref: TM-T200948

  • LX2761
    Targetmol
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    LX2761

    CAS:
    <p>LX2761 is a stable inhibitor for SGLT1/2 with IC50s of 2.2/2.7 nM; it targets SGLT1 in the GI tract.</p>
    Formula:C32H47N3O6S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:601.80

    Ref: TM-T15797

  • Nedocromil sodium
    Targetmol
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    Nedocromil sodium

    CAS:
    <p>Nedocromil sodium is a pharmacologic stabilizer of mast cells, has been shown to normalize cytokine levels and attenuate cardiac remodeling.</p>
    Formula:C19H17NNaO7
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:394.335

    Ref: TM-T19472

  • Setomagpran
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    Setomagpran

    CAS:
    <p>Setomagpran is an antagonist of the mas-related G protein-coupled receptor (MRGPR) and possesses anti-inflammatory properties.</p>
    Formula:C22H19Cl2F6N5O
    Colore e forma:Solid
    Peso molecolare:554.316

    Ref: TM-T206418

  • ASN-1377642
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    ASN-1377642

    CAS:
    <p>ASN-1377642 is an NK1 receptor antagonist with a Ki value of 251 nM. It demonstrates antitumor activity in breast cancer cells with high expression of NK1R-Tr.</p>
    Formula:C21H16ClN5OS
    Colore e forma:Solid
    Peso molecolare:421.90

    Ref: TM-T207218

  • LY 292728
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    LY 292728

    CAS:
    <p>LY 292728 is a highly potent antagonist of leukotriene B4 receptor.</p>
    Formula:C34H29FO9
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:600.59

    Ref: TM-T27913

  • 8-iso Prostaglandin F3α
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    8-iso Prostaglandin F3α

    CAS:
    <p>8-iso PGF3α is an isoprostane produced from the free-radical peroxidation of EPA.</p>
    Formula:C20H32O5
    Colore e forma:Solid
    Peso molecolare:352.47

    Ref: TM-T36164

  • GLP-1 receptor agonist 16
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    GLP-1 receptor agonist 16

    CAS:
    <p>GLP-1 receptoragonist 16 (Example 53) is a GLP-1 agonist applicable for research in diabetes, obesity, or diseases related to non-alcoholic steatohepatitis.</p>
    Formula:C33H31ClFN3O4
    Colore e forma:Solid
    Peso molecolare:588.068

    Ref: TM-T204526

  • MK-0812
    Targetmol
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    MK-0812

    CAS:
    <p>MK-0812 is a dual antagonist of the CCR2 and CCR5 receptors that can alleviate adipose inflammation in ob/ob mice.</p>
    Formula:C24H34F3N3O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:469.54

    Ref: TM-TQ0182

  • KMN-80
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    KMN-80

    CAS:
    <p>KMN-80 is a potent, selective EP4 agonist with IC50 3 nM, spurring osteoblast differentiation, and showing in vivo bone repair efficacy.</p>
    Formula:C21H33NO4
    Colore e forma:Solid
    Peso molecolare:363.49

    Ref: TM-T37441

  • EP-3945
    Targetmol
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    EP-3945

    CAS:
    <p>EP-3945 is an agonist of Mas-related G protein-coupled receptors (MRGPR), exhibiting greater potency than the small molecule agonist β-Alanine targeting MRGPRD. MRGPRs play a crucial role in inflammatory itch and pain perception. These receptors interact with Gq (MRGPRX2, MRGPRX4, and MRGPRX1 are coupled with Gq; MRGPRX2 and MRGPRD couple with Gi), with EP-3945 having an EC50 value of 211.6 nM for Gq.</p>
    Formula:C24H26N4O3
    Colore e forma:Solid
    Peso molecolare:418.488

    Ref: TM-T205219

  • TAK-637
    Targetmol
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    TAK-637

    CAS:
    <p>TAK-637 is a tachykinin 1 (NK1) receptor antagonist.</p>
    Formula:C30H25F6N3O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:573.53

    Ref: TM-T28917

  • Logo CymitQuimica
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    LJ-4517

    <p>LJ-4517 is an effective A2AAR antagonist (Ki=18.3 nM). LJ-4517 can effectively replace the binding of [3H] ZM241385 at WT A2AAR.</p>
    Formula:C19H21N5O3S
    Colore e forma:Solid
    Peso molecolare:399.47

    Ref: TM-T61914

  • TAAR1 agonist 2
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    TAAR1 agonist 2

    CAS:
    <p>TAAR1 agonist 2 (compound 30), a full agonist at trace amine-associated receptor 1 (TAAR1) (pEC50=7.5), also displays agonistic properties at H1 receptors and activates various muscarinic acetylcholine receptors, including the M2 receptor (pEC50=5). This compound is utilized in researching neuropsychiatric diseases.</p>
    Formula:C9H11NO
    Colore e forma:Solid
    Peso molecolare:149.19

    Ref: TM-T200140

  • SJPYT-310
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    SJPYT-310

    CAS:
    <p>SJPYT-310 is a selective PXR antagonist, exhibiting no noticeable cytotoxicity.</p>
    Formula:C27H36N4O3
    Colore e forma:Solid
    Peso molecolare:464.6

    Ref: TM-T205404

  • DA-302168S
    Targetmol
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    DA-302168S

    CAS:
    <p>DA-302168S is an orally active, selective GLP-1R agonist with an EC50 value of 1.32 nM. It promotes insulin secretion and has a hypoglycemic effect. Additionally, DA-302168S reduces food intake. It primarily activates GLP-1R in humans and monkeys, with minimal effect on GLP-1R in rats, mice, and dogs. DA-302168S can be used for research in type 2 diabetes and obesity.</p>
    Formula:C33H24ClF2N3O5
    Colore e forma:Solid
    Peso molecolare:616.011

    Ref: TM-T206917

  • SB 243213 dihydrochloride
    Targetmol
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    SB 243213 dihydrochloride

    CAS:
    <p>SB 243213 dihydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8 for</p>
    Formula:C22H21Cl2F3N4O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:501.33

    Ref: TM-T12859L

  • MK-3207
    Targetmol
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    MK-3207

    CAS:
    <p>MK-3207 is a potent, oral CGRP receptor antagonist with high selectivity for human and monkey receptors, inhibiting blood flow in vivo.</p>
    Formula:C31H29F2N5O3
    Colore e forma:Solid
    Peso molecolare:557.59

    Ref: TM-T21558

  • Metrazoline
    Targetmol
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    Metrazoline

    CAS:
    <p>Metrazoline (o-Methyl-tracizoline) acts as a ligand for adrenergic receptors (low affinity) and imidazoline I2 receptors.</p>
    Formula:C14H16N2O4
    Colore e forma:Solid
    Peso molecolare:276.288

    Ref: TM-T204804

  • BI-44370
    Targetmol
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    BI-44370

    CAS:
    <p>BI-44370, a CGRP (calcitonin gene-related peptide) receptor antagonist, can be used to treat migraines and other chronic pain.</p>
    Formula:C35H47N5O6
    Colore e forma:Solid
    Peso molecolare:633.78

    Ref: TM-T26796