CymitQuimica logo
Proteina G/GPCR

Proteina G/GPCR

Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.

Sottocategorie di "Proteina G/GPCR"

Mostrare 18 più sottocategorie

Trovati 5352 prodotti di "Proteina G/GPCR"

Ordinare per

Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
prodotti per pagina.
  • BI 639667

    CAS:
    <p>BI 639667, an azaindazole-class compound, potently inhibits CCR1 (IC50=1.8 nM in calcium flux assays).</p>
    Formula:C22H18FN5O3S
    Purezza:99.86%
    Colore e forma:Solid
    Peso molecolare:451.47
  • SB-423557

    CAS:
    <p>SB-423557 is an orally active antagonist of calcium-sensing receptor (CaR) with IC50 of 520 nM</p>
    Formula:C28H36N2O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:464.60
  • LTD4 antagonist 1

    CAS:
    <p>LTD4 antagonist 1 is a potent and orally active antagonist of leukotriene D4 (LTD4; Ki: 0.57 nM).</p>
    Formula:C31H32F3N3O5S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:615.66
  • Pareptide monohydrochloride

    CAS:
    <p>Pareptide monohydrochloride is a metabolically stable analog of melatonin inhibitor (MIF).</p>
    Formula:C14H27ClN4O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:334.84
  • PD 136450

    CAS:
    <p>PD-136,450: partial stomach secretory agonist, full pancreas agonist in rats; potential acid-reducing drug, adjuvant for gastrin-sensitive tumors.</p>
    Formula:C35H40N4O6
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:612.72
  • (1R,2S,3R)-Aprepitant

    CAS:
    <p>(1R,2S,3R)-Aprepitant (Compound ent-4) is a competitive antagonist of the human neurokinin-1 (NK-1) receptor. It holds potential for research in the treatment of nausea and vomiting related to cancer or postoperative conditions.</p>
    Formula:C23H21F7N4O3
    Colore e forma:Solid
    Peso molecolare:534.427
  • AL 8810

    CAS:
    <p>AL-8810 is an 11β-fluoro analog of PGF 2α with selective antagonist effects at the PGF 2α receptor (FP receptor) [1].</p>
    Formula:C24H31FO4
    Colore e forma:Solid
    Peso molecolare:402.5
  • Zafirlukast metabolite M1

    CAS:
    <p>Zafirlukast metabolite M1 (compound 15) is an inhibitor used in the treatment of asthma and other allergic pulmonary conditions, effectively antagonizing leukotriene activity.</p>
    Formula:C25H25N3O4S
    Colore e forma:Solid
    Peso molecolare:463.549
  • PF-06372222

    CAS:
    <p>PF-06372222: a small-molecule that modulates GCGR and antagonizes GLP-1R, affecting insulin and glucagon.</p>
    Formula:C26H28F3N5O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:515.53
  • GHSR-1a agonist-1

    CAS:
    <p>GHSR-1a agonist-1 (Compound 4b) is an orally active agonist of the human growth hormone secretagogue receptor 1a (GHSR-1a) with an EC50 of 0.49 nM. It effectively stimulates the release of endogenous growth hormone by activating GHSR-1a. Doses as low as 0.1 mg/kg (administered orally) can increase body weight and length in 4-week-old rats. GHSR-1a agonist-1 is applicable in research on pediatric growth and developmental delays.</p>
    Formula:C30H37N5O4
    Colore e forma:Solid
    Peso molecolare:531.646
  • Gemilukast

    CAS:
    <p>Gemilukast (ONO-6950) is a cysteinyl leukotriene 1 and 2 receptor inhibitor that inhibits bronchoconstriction and is used in the treatment of asthma.</p>
    Formula:C36H37F2NO5
    Purezza:98.27% - 99.5%
    Colore e forma:Solid
    Peso molecolare:601.68
  • GnRH-R antagonist 1

    CAS:
    <p>Compound 21a: Oral GnRH-R antagonist, IC50=0.57 nM, potent against prostate cancer/prevents LH surges.</p>
    Formula:C31H28F5N7O6S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:721.65
  • SGLT inhibitor-1

    CAS:
    <p>SGLT inhibitor-1 is a potentsodium glucose co-transporter proteins (SGLTs) dual inhibitor(hSGLT1 and hSGLT2 with IC50s of 43 nM and 9 nM, respectively).</p>
    Formula:C24H27FO8
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:462.46
  • (S)-Praziquantel

    CAS:
    <p>(S)-Praziquantel is the inactive isomer of R-praziquantel.</p>
    Formula:C19H24N2O2
    Colore e forma:Solid
    Peso molecolare:312.406
  • ZK118182 isopropyl ester

    CAS:
    <p>ZK118182 isopropyl ester is a PG analog with potent DP-agonist activity (EC50 = 16.5 nM) and high affinity for the DP receptor (Ki = 74 nM).</p>
    Formula:C23H37ClO5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:428.99
  • BIBO3304 diTFA

    CAS:
    <p>BIBO3304 (diTFA), a selective neuropeptide Y (NPY) Y1 receptor antagonist, demonstrates oral efficacy. It exhibits high affinity for Y1 receptors in both humans and rats, with IC50 values of 0.38 nM and 0.72 nM, respectively. Additionally, BIBO3304 (diTFA) enhances bone-tendon healing via the Wnt/β-catenin signaling pathway [1] [2] [3].</p>
    Formula:C33H37F6N7O7
    Colore e forma:Solid
    Peso molecolare:757.68
  • KF26777

    CAS:
    <p>KF26777 is a potent and selective antagonist of adenosine A3 receptor.</p>
    Formula:C16H16BrN5O
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:374.23
  • KMN-80

    CAS:
    <p>KMN-80 is a potent, selective EP4 agonist with IC50 3 nM, spurring osteoblast differentiation, and showing in vivo bone repair efficacy.</p>
    Formula:C21H33NO4
    Colore e forma:Solid
    Peso molecolare:363.49
  • Butopamine hydrochloride

    CAS:
    <p>Butopamine hydrochloride is an orally active inotropic compound that is more effective at increasing heart rate compared to Dobutamine.</p>
    Formula:C18H24ClNO3
    Colore e forma:Solid
    Peso molecolare:337.84
  • D4R antagonis-2


    <p>Potent D4R antagonist-2: selective, IC50=6.52 μM, good in vitro PK and brain penetration, potential for Parkinson's research.</p>
    Formula:C21H23ClF2N2O2
    Colore e forma:Solid
    Peso molecolare:408.87
  • BI-113823

    CAS:
    <p>BI-113823 is an orally active and selective bradykinin B1 receptor antagonist. It alleviates mechanical hyperalgesia induced by complete Freund's adjuvant in rats. BI-113823 is applicable for research on chronic inflammatory pain.</p>
    Formula:C26H44N4O5S
    Colore e forma:Solid
    Peso molecolare:524.716
  • Zaladenant

    CAS:
    <p>Zaladenant is an adenosine receptor antagonist with antitumor properties.</p>
    Formula:C19H15F3N6O
    Colore e forma:Solid
    Peso molecolare:400.357
  • D3/5-HT receptor modulator-1

    CAS:
    <p>D3/5-HT receptor modulator-1 (compound 5i) is a selective antagonist of the dopamine D3 and 5-HT2A receptors, and a partial agonist at the 5-HT1A receptor. It exhibits Ki values of 4.5 nM, 11.9 nM, and 15.3 nM for the dopamine D3, 5-HT2A, and 5-HT1A receptors respectively. The compound shows lower affinity for the dopamine D2 receptor, 5-HT2C receptor, and hERG channel. D3/5-HT receptor modulator-1 possesses atypical antipsychotic properties.</p>
    Formula:C24H29N3O2
    Colore e forma:Solid
    Peso molecolare:391.506
  • 25B-NBOH hydrochloride

    CAS:
    <p>25B-NBOH hydrochloride is a phenethylamine that exhibits high affinity for serotonin (5-HT) receptors 5-HT2A and 5-HT2C, with pKi values of 8.3 and 9.4, respectively.</p>
    Formula:C17H21BrClNO3
    Colore e forma:Solid
    Peso molecolare:402.711
  • CCR7 Ligand 1

    CAS:
    <p>CCR7-Cmp2105 is a thiadiazole-dioxide allosteric antagonist for CCR7 with a Kd of 3 nM and IC50 of 7.3 μM against arrestin binding.</p>
    Formula:C22H29N5O5S
    Colore e forma:Solid
    Peso molecolare:475.56
  • MRGPRX2 modulator-1

    CAS:
    <p>MRGPRX2 modulator-1 (example 17), a modulator of the mas-related G-protein receptor X2 (MRGPRX2), is employed in studies focused on inflammation, pain, and autoimmune disorders [1].</p>
    Formula:C20H19F6N5O
    Colore e forma:Solid
    Peso molecolare:459.39
  • LY3154207

    CAS:
    <p>LY3154207: selective, potent oral human dopamine D1 receptor PAM, low agonist activity, EC50=3 nM.</p>
    Formula:C24H29Cl2NO3
    Colore e forma:Solid
    Peso molecolare:450.4
  • RU 52583

    CAS:
    <p>RU 52583 is an alpha 2-adrenergic receptor antagonist.</p>
    Formula:C18H20N2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:264.36
  • Elzasonan hydrochloride

    CAS:
    <p>Elzasonan hydrochloride is a serotonin 1B and serotonin 1D receptor antagonist. It is utilized in the study of depression.</p>
    Formula:C22H24Cl3N3OS
    Colore e forma:Solid
    Peso molecolare:484.87
  • GRK6-IN-5

    CAS:
    <p>GRK6-IN-5 is an inhibitor of the GRK6 polypeptide, with an IC50 of 4.48 μM. GRK6-IN-5 is utilized in research focused on hematological malignancies, inflammatory diseases, and autoimmune disorders.</p>
    Formula:C23H21N3O2
    Colore e forma:Solid
    Peso molecolare:371.432
  • Mrgx2 antagonist-3

    CAS:
    <p>Mrgx2 antagonist-3 (Compound B-40) is a highly selective antagonist of the MrgX2 receptor, with an IC50 range of 0.042-2.5 nM. It blocks downstream G protein signaling and β-arrestin recruitment, inhibiting Mrgx2 receptor-mediated calcium influx and cell degranulation. Mrgx2 antagonist-3 shows potential for research in inflammation-associated diseases and pruritus, such as chronic urticaria and allergic asthma.</p>
    Formula:C15H15F2N3O
    Colore e forma:Solid
    Peso molecolare:291.30
  • EP4 receptor agonist 3

    CAS:
    <p>EP4 receptor agonist 3 is an activator of the EP4 receptor and is useful for research in the DSS-induced colitis mouse model.</p>
    Formula:C21H27F2NO4
    Colore e forma:Solid
    Peso molecolare:395.44
  • SR 140333

    CAS:
    <p>SR 140333 is a NK1 receptor antagonist.</p>
    Formula:C37H45Cl3N2O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:656.12
  • Rodatristat ethyl

    CAS:
    <p>Rodatristat ethyl is an oral TPH1 inhibitor reducing 5-HT levels &amp; lowering PAH at low doses.</p>
    Formula:C29H31ClF3N5O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:590.04
  • BRD50837

    CAS:
    <p>BRD50837 is a potent and selective inhibitor of Sonic Hedgehog (Shh).</p>
    Formula:C26H32ClN3O6S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:550.07
  • Aplaviroc hydrochloride

    CAS:
    <p>Aplaviroc, a potent CCR5 inhibitor, binds selectively, blocking HIV entry and specific monoclonal antibody attachment in vitro.</p>
    Formula:C33H44ClN3O6
    Colore e forma:Solid
    Peso molecolare:614.17
  • Abarelix acetate

    CAS:
    <p>Abarelix acetate: synthetic GnRHR antagonist, spikes histamine, lowers LH and testosterone temporarily, used in advanced prostate cancer.</p>
    Formula:C72H95ClN14O14·xC2H4O2
    Colore e forma:Solid
    Peso molecolare:1476.14
  • L-657926

    CAS:
    <p>L-657926 is a stereoselective antagonist of the thromboxane A2 (TxA2) receptor, composed of (-)-9-chlorobenzyl-6-fluoro-1,2,3,4-tetrahydrocarbazol-1-yl acetic acid and (+)-9-chlorobenzyl-6-fluoro-1,2,3,4-tetrahydrocarbazol-1-yl acetic acid. The IC50 values for the (-) and (+) configurations against TxA2 are 0.27 nM and 124 nM, respectively.</p>
    Formula:C21H19ClFNO2
    Colore e forma:Solid
    Peso molecolare:371.832
  • Tebideutorexant

    CAS:
    <p>Tebideutorexant, an orexin-1 receptor antagonist, shows anti-panic effects in rodents and humans, providing a tool for stress response and psychiatric research.</p>
    Formula:C23H16D2F4N4O2
    Purezza:98.89%
    Colore e forma:Solid
    Peso molecolare:460.42
  • BNS808

    CAS:
    <p>BNS808 is an orally active, selective CB1R antagonist with an IC50 of 0.8 nM, demonstrating significant selectivity for CB2R and minimal brain penetration. It is being studied for the treatment of obesity and related metabolic complications, such as metabolic dysfunction-associated steatotic liver disease (MASLD). BNS808 reduces drug exposure to the central nervous system, enhancing safety, and minimizes drug interactions through high plasma protein binding.</p>
    Formula:C25H20Cl3N3O3S
    Colore e forma:Solid
    Peso molecolare:548.869
  • MK-0812

    CAS:
    <p>MK-0812 is a dual antagonist of the CCR2 and CCR5 receptors that can alleviate adipose inflammation in ob/ob mice.</p>
    Formula:C24H34F3N3O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:469.54
  • 5-HT6R/MAO-B modulator 1


    <p>5-HT6R/MAO-B modulator 1 blocks 5-HT6R and permanently inhibits MAO-B, protects glial cells, and reverses memory loss.</p>
    Formula:C33H38N4O3S
    Colore e forma:Solid
    Peso molecolare:570.74
  • CCG258208

    CAS:
    <p>GRKs-IN-1 has remarkable potency against and selectivity for G protein-coupled receptor kinase 2 GRK2 (IC50: 130 nM) and GRK5 (IC50: 7.1 μM).</p>
    Formula:C24H25FN4O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:452.48
  • D1R antagonist 1

    CAS:
    <p>Compound 12a (D1R antagonist 1) is a D1R antagonist that participates in both G-protein-coupled and β-arrestin-mediated signaling pathways [1].</p>
    Formula:C22H26BrNO4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:448.35
  • 5-HT7R antagonist 3

    CAS:
    <p>Compound 6.4, also known as 5-HT7R antagonist 3, is a selective antagonist of the 5-HT7R with a Ki of 8 nM. It exhibits significantly less affinity towards D2R, 5-HT1AR, and 5-HT2AR with Ki values of 511 nM, 8930 nM, and 5786 nM, respectively. In mice, 5-HT7R antagonist 3 demonstrates anti-depressant and anti-anxiety activities.</p>
    Formula:C30H33FN4O3
    Colore e forma:Solid
    Peso molecolare:516.61
  • GLP-1 receptor agonist 15

    CAS:
    <p>GLP-1 receptor agonist 15 (Example 4) is a GLP receptor agonist with an EC50 of 0.74 nM. It exhibits an IC50 of 10.1 μM against the hERG potassium ion channel. This compound is applicable for research in the diabetes field.</p>
    Formula:C32H31ClFN3O5
    Colore e forma:Solid
    Peso molecolare:592.057
  • M1069


    <p>M1069 is an oral A2A/A2B receptor antagonist, 100x more selective over A1/A3, with antitumor properties by blocking adenosine's immunosuppressive effects.</p>
    Formula:C25H30N4O8S
    Colore e forma:Solid
    Peso molecolare:546.59
  • MRS2279

    CAS:
    <p>Selective, high affinity competitive antagonist of the P2Y1 receptor</p>
    Formula:C13H18ClN5O8P2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:469.71
  • AFP-07

    CAS:
    <p>AFP-07 is a highly selective and potent agonist. It was used for the prostacyclin receptor.</p>
    Formula:C22H29F2NaO5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:434.45
  • F 14679

    CAS:
    <p>F 14679 is a potent 5-HT1A agonist (pKi=10.23) with a maximum Ca2t response similar to 5-HT.</p>
    Formula:C21H25ClF2N4O
    Purezza:99.09%
    Colore e forma:Solid
    Peso molecolare:422.9
  • HU 433

    CAS:
    <p>HU 433, a synthetic cannabinoid, acts as a CB2 receptor agonist and is an enantiomer of HU 308. It provides anti-inflammatory and neuroprotective effects by binding to the CB2 receptor, primarily found on immune cells, thereby modulating immune responses and inflammation. Additionally, HU 433 influences microglial signaling pathways, particularly LPS and IFNγ-mediated routes, affecting the phosphorylation of MAPKs, including ERK1/2, JNK, p38, and Akt. This compound is valuable in researching neuroinflammation and retinal diseases.</p>
    Formula:C27H42O3
    Colore e forma:Solid
    Peso molecolare:414.62
  • Leukotriene B4 dimethyl amide

    CAS:
    <p>LTB4 dimethyl amide: inhibits human neutrophil degranulation and rat lysozyme release; antagonizes LTB4 receptor on guinea pig lung membranes (Ki = 130 nM).</p>
    Formula:C22H37NO3
    Colore e forma:Solid
    Peso molecolare:363.53
  • BAY 38-7271

    CAS:
    <p>BAY 38-7271: potent neuroprotective, selective CB1/CB2 agonist, Ki of 1.85 nM (CB1) &amp; 5.96 nM (CB2).</p>
    Formula:C20H21F3O5S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:430.44
  • Nocloprost

    CAS:
    <p>Nocloprost (SH 475) is a prostaglandin E2 (PGE2) analog, an EP1 and EP3 receptor agonist with local gastric protection and ulcer healing effects.</p>
    Formula:C22H37ClO4
    Colore e forma:Solid
    Peso molecolare:400.98
  • UR-AK49

    CAS:
    <p>UR-AK49 (compound 11) is an agonist for the human histamine H1 and H2 receptors. It exhibits an EC50 of 23 nM in the GTPase assay involving hH2R-Gsalpha fusion protein expressed in Sf9 insect cells. UR-AK49 is applicable in neurologically related research.</p>
    Formula:C16H27N5O
    Colore e forma:Solid
    Peso molecolare:305.42
  • UNC10099984A

    CAS:
    <p>UNC10099984A (Compound 6) is a functionally selective ligand for the dopamine D2 receptor, exhibiting a Ki value of 4.6 nM and an EC50 of 6.2 nM for β-arrestin. This compound is useful for research into central nervous system diseases related to the D2 receptor.</p>
    Formula:C24H29Cl2N3O2
    Colore e forma:Solid
    Peso molecolare:462.41
  • Tixanox sodium

    CAS:
    <p>Tixanox sodium effectively blocks histamine release in the lungs triggered by anti-IgE. It has also been demonstrated that when administered orally, Tixanox sodium can successfully counteract exercise-induced asthma.</p>
    Formula:C15H9NaO5S
    Colore e forma:Solid
    Peso molecolare:324.28
  • YM-49598 iodide

    CAS:
    <p>YM-49598 iodide is a tachykinin NK-1 receptor antagonist. It inhibits drug-induced bladder contractions in rats with an IC50 of 11 μg/kg.</p>
    Formula:C36H45Cl2IN2O2
    Colore e forma:Solid
    Peso molecolare:735.57
  • PAR4 antagonist 3

    CAS:
    <p>PAR4 antagonist3 (Compound 36) is a selective antagonist of protease-activated receptor 4 (PAR4). It exhibits antiplatelet activity with an IC50 of 26.1 nM and enhances metabolic stability in human liver microsomes, with a half-life (T1/2) of 97.6 minutes.</p>
    Formula:C22H16FN3O5S
    Peso molecolare:453.44
  • GnRH antagonist 2

    CAS:
    <p>GnRH antagonist 2 is a GnRH receptor antagonist, useful for studying endocrine diseases.</p>
    Formula:C28H27F2N9O5
    Purezza:98.08%
    Colore e forma:Solid
    Peso molecolare:607.57
  • R-96544 hydrochloride

    CAS:
    <p>5-HT2 receptor antagonist</p>
    Formula:C22H29NO3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:355.47
  • (R)-MrgprX2 antagonist-3

    CAS:
    <p>(R)-MrgprX2 antagonist-3 is an antagonist of MrgprX2. It is applicable in the study of inflammatory skin diseases. For more detailed information, please refer to compound E118 in patent document WO2021092240A1.</p>
    Formula:C16H20FN3O2S
    Peso molecolare:337.41
  • Alixorexton

    CAS:
    <p>Alixorexton is an agonist of the orexin-2 receptor (orexin-2 receptor) and is utilized in obesity research.</p>
    Formula:C21H30N2O5S
    Colore e forma:Solid
    Peso molecolare:422.538
  • Serlopitant

    CAS:
    <p>Serlopitant is a selective antagonist of Neurokinin-1 (NK-1) receptor.</p>
    Formula:C29H28F7NO2
    Colore e forma:Solid
    Peso molecolare:555.53
  • Cendifensine

    CAS:
    <p>Cendifensine functions as a monoamine reuptake inhibitor, targeting the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT).</p>
    Formula:C14H17Cl2NO
    Colore e forma:Solid
    Peso molecolare:286.197
  • AGH-107

    CAS:
    <p>AGH-107 is a highly selective 5-HT7 receptor agonist that can cross the blood-brain barrier, featuring a Ki value of 6 nM and an EC50 value of 19 nM. Demonstrating high selectivity for central nervous system targets, AGH-107 also exhibits high metabolic stability and low toxicity in HEK-293 and HepG2 cell cultures.</p>
    Formula:C13H12IN3
    Colore e forma:Solid
    Peso molecolare:337.16
  • CB2R/5-HT1AR agonist 1

    CAS:
    <p>Compound 2o, also known as CB2R/5-HT1AR agonist 1, serves as a partial orally active agonist for the CB2 receptor (EC50 = 479.6 nM) and a full agonist for the 5-HT1A receptor (EC50 = 2.7 μM). This compound demonstrates both anti-anxiety and anti-depressive effects and has favorable pharmacokinetic properties [1].</p>
    Formula:C24H33NO3
    Colore e forma:Solid
    Peso molecolare:383.52
  • Flucopride

    CAS:
    <p>Flucopride (Compound 4a) acts as an acetylcholinesterase inhibitor (AChE) with an IC50 value of 24 nM and serves as a partial agonist for the human 5-HT4 receptor (5-HT4R) with a Ki of 9.6 nM for (h)5-HT4R. It promotes non-amyloidogenic processing of APP in COS-7 cells transiently expressing (h)5-HT4R with an EC50 of 23.0 nM. Flucopride is also likely to exhibit significant gastrointestinal tract (GIT) penetration and blood-brain barrier (BBB) permeability, as determined in PAMPA experiments.</p>
    Formula:C22H33FN2O2
    Colore e forma:Solid
    Peso molecolare:376.51
  • R-137696

    CAS:
    <p>R-137696 is an orally active 5-HT1A receptor agonist that facilitates the relaxation of the proximal stomach. It is utilized in research related to functional dyspepsia.</p>
    Formula:C17H23N3O2
    Colore e forma:Solid
    Peso molecolare:301.38
  • MDA77

    CAS:
    <p>MDA77 is a CB2 agonist with an EC50 value of 5.82 nM and exhibits no activity towards CB1.</p>
    Formula:C21H23N3O3
    Colore e forma:Solid
    Peso molecolare:365.43
  • COX-2-IN-6

    CAS:
    <p>COX-2-IN-6: Potent, selective COX-2 inhibitor; oral; IC50 0.84μM, Ki 69nM; blocks PGE2 synthesis; prevents colorectal cancer.</p>
    Formula:C20H27NO6S
    Purezza:99.29% - 99.69%
    Colore e forma:Soild
    Peso molecolare:409.5
  • Protease-Activated Receptor-1 antagonist 2


    <p>Selective, orally active PAR-1 antagonist with an IC50 of 7 nM, potential for cardiovascular disease studies.</p>
    Colore e forma:Solid
  • Toladryl

    CAS:
    <p>Toladryl is a derivative of Diphenhydramine that can cross the blood-brain barrier and exhibits oral activity, with antihistamine and anticholinergic properties. Its anticholinergic effects are approximately a tenth of those seen with Diphenhydramine, yet it offers 2-4 times the protection against lethal doses of histamine in guinea pigs. The side effects of Toladryl are fewer and milder compared to Diphenhydramine; however, at higher doses, it may cause symptoms such as insomnia, agitation, and disorientation related to the central nervous system. Toladryl is utilized in the research of allergic diseases.</p>
    Formula:C18H23NO
    Colore e forma:Solid
    Peso molecolare:269.38
  • Disulergine

    CAS:
    <p>Disulergine is a dopamine receptor agonist. It also prolactin release-inhibiting 8 alpha-amino-ergoline.</p>
    Formula:C17H24N4O2S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:348.46
  • MRT-92

    CAS:
    <p>MRT-92 is an antagonist of Smoothened (Smo) with anti-cancer activity, featuring a binding affinity (Ki) of 0.7 nM. It inhibits the Hedgehog signaling pathway by obstructing the overlapping binding sites within the transmembrane domain of the Smoothened receptor and suppresses the proliferation of cerebellar granule cells in rodents (IC50=0.4 nM). MRT-92 is utilized for research into cerebellar gliomas.</p>
    Formula:C33H34N4O5
    Colore e forma:Solid
    Peso molecolare:566.65
  • LK 11

    CAS:
    <p>LK-11, an alkaloid derivative, inhibits the passive uptake of norepinephrine (NA) by synaptic vesicles in the thalamus, similarly to cocaine.</p>
    Formula:C15H26N2O3
    Colore e forma:Solid
    Peso molecolare:282.38
  • Remlifanserin

    CAS:
    <p>Remlifanserin is a potent inverse agonist of the serotonin receptor (5-HT2A).</p>
    Formula:C24H29F2N3O2
    Colore e forma:Solid
    Peso molecolare:429.50
  • RF9 hydrochloride


    <p>RF9 hydrochloride is a potent and selective Neuropeptide FF receptor antagonist that acts on hNPFF1R (Ki: 58 nM) and hNPFF2R (Ki: 7 nM).</p>
    Formula:C26H39ClN6O3
    Colore e forma:Solid
    Peso molecolare:519.08
  • CB1/2 agonist 1


    <p>Potent CB1/2 agonist 1; crosses blood-brain barrier; anti-inflammatory, analgesic; for multiple sclerosis research.</p>
    Formula:C21H24BrFN2O2
    Colore e forma:Solid
    Peso molecolare:435.33
  • Beloxepin

    CAS:
    <p>Beloxepin is an oral dual selective inhibitor of serotonin and norepinephrine uptake.</p>
    Formula:C19H21NO2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:295.38
  • NK-1 Antagonist 1

    CAS:
    <p>NK-1 Antagonist 1 is a NK-1 receptor antagonist.</p>
    Formula:C25H23F6N5O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:539.47
  • SR 142948-C3-NHMe

    CAS:
    <p>SR 142948-C3-NHMe is the methylated form of SR 142948.</p>
    Formula:C42H58N6O6
    Colore e forma:Solid
    Peso molecolare:742.946
  • Serotonin maleate

    CAS:
    <p>Serotonin hydrogen maleate serves as a monoaminergic neurotransmitter and an endogenous 5-HT receptor agonist within the central nervous system (CNS). It also functions as an inhibitor of catechol O-methyltransferase (COMT), exhibiting a Ki value of 44 μM.</p>
    Formula:C14H16N2O5
    Colore e forma:Solid
    Peso molecolare:292.287
  • Opipramol dihydrochloride

    CAS:
    <p>Opipramol (Ensidon) is an atypical tricyclic antidepressant (TCA) primarily functioning as a sigma (σ) receptor agonist. It interacts effectively with sigma recognition sites, having a Ki value of 50 nM. Opipramol is applicable in the study of generalized anxiety disorder (GAD).</p>
    Formula:C23H31Cl2N3O
    Colore e forma:Solid
    Peso molecolare:436.418
  • CRHR1 antagonist 1

    CAS:
    <p>CRHR1 antagonist 1 (compound 10a) is a non-peptide antagonist of corticotropin-releasing hormone receptor 1 (CRHR1). It serves as a useful tool in the study of psychiatric disorders.</p>
    Formula:C24H34N4O
    Colore e forma:Solid
    Peso molecolare:394.553
  • LX2761

    CAS:
    <p>LX2761 is a stable inhibitor for SGLT1/2 with IC50s of 2.2/2.7 nM; it targets SGLT1 in the GI tract.</p>
    Formula:C32H47N3O6S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:601.80
  • Setomagpran

    CAS:
    <p>Setomagpran is an antagonist of the mas-related G protein-coupled receptor (MRGPR) and possesses anti-inflammatory properties.</p>
    Formula:C22H19Cl2F6N5O
    Colore e forma:Solid
    Peso molecolare:554.316
  • SphK1-IN-1


    <p>SphK1-IN-1: SphK1 ATPase inhibitor, IC50=2.48 μM, potential for cancer research.</p>
    Formula:C22H22N6O2
    Colore e forma:Solid
    Peso molecolare:402.45
  • RGS10 modulator-1

    CAS:
    <p>RGS10 modulator-1 (compound 15) is an effective regulator of RGS10. It significantly reverses IFNγ-induced expression of both RGS10 protein and mRNA, as well as COX-2 mRNA and iNOS expression triggered by IFNγ.</p>
    Formula:C16H15BrN2O3S2
    Colore e forma:Solid
    Peso molecolare:427.336
  • CCR1 antagonist 11 hydrochloride


    <p>Oral CCR1 antagonist A1B1 targets h/m/rCCR1 (IC50: 0.03/0.58/0.32 μM), potential for treating inflammatory diseases.</p>
    Colore e forma:Solid
  • BMS-986141

    CAS:
    <p>BMS-986141(UDM-003183) is a selective and potent protease-activated receptor-4 (PAR-4) antagonist with oral activity and an IC50 value of 0.4 nM.BMS-98614</p>
    Formula:C27H23N5O5S2
    Purezza:98.43% - 99.26%
    Colore e forma:Solid
    Peso molecolare:561.63
  • AZD5462

    CAS:
    <p>AZD5462 is a potent orally available relaxin receptor RXFP1 agonist for the study of heart failure and cancer.</p>
    Formula:C30H41FN2O6
    Purezza:98.32% - 99.63%
    Colore e forma:Solid
    Peso molecolare:544.65
  • PF-07258669

    CAS:
    <p>PF-07258669 is a selective melanocortin 4 receptor (MC4) antagonist used in the study of cachexia and loss of appetite.</p>
    Formula:C25H27FN6O2
    Purezza:99.9%
    Colore e forma:Solid
    Peso molecolare:462.52
  • BQ-788

    CAS:
    <p>BQ-788 is an ETB receptor antagonist with potential hypertensive activity that inhibits exogenous ET-1-induced elevation of coronary perfusion pressure.</p>
    Formula:C34H51N5O7
    Purezza:98.81%
    Colore e forma:Solid
    Peso molecolare:641.8
  • Vofopitant dihydrochloride

    CAS:
    <p>Vofopitant dihydrochloride (GR 205171A) is a tachykinin NK1 receptor antagonist and a potential compound for the treatment of pathologic vomiting.</p>
    Formula:C21H25Cl2F3N6O
    Purezza:98.99%
    Colore e forma:Solid
    Peso molecolare:505.36
  • Dersimelagon

    CAS:
    <p>Dersimelagon (MT-7117) is an orally active, selective melanocortin 1 receptor (MC1R) agonist.Cost-effective and quality-assured.</p>
    Formula:C36H45F4N3O5
    Purezza:97.35% - 98.23%
    Colore e forma:Solid
    Peso molecolare:675.75
  • Vofopitant

    CAS:
    <p>Vofopitant (GR 205171) is a potent NK1 receptor antagonist with anxiolytic and antiemetic activity for the study of post-traumatic stress disorder (PTSD).</p>
    Formula:C21H23F3N6O
    Purezza:97.86%
    Colore e forma:Solid
    Peso molecolare:432.44
  • AZD-5672

    CAS:
    <p>AZD-5672 is an antagonist of CCR5 with an IC50 of 0.32 nM.</p>
    Formula:C32H38F2N2O5S2
    Purezza:98.1%
    Colore e forma:Solid
    Peso molecolare:632.78
  • Treprostinil diethanolamine

    CAS:
    <p>Treprostinil diethanolamine (UT-15C) is a potent agonist of EP2, DP1 and IP, with values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1,</p>
    Formula:C27H45NO7
    Purezza:99.86%
    Colore e forma:Solid
    Peso molecolare:495.65
  • SB-224289 hydrochloride

    CAS:
    <p>SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect.</p>
    Formula:C32H33ClN4O3
    Purezza:97.82% - 98.99%
    Colore e forma:Solid
    Peso molecolare:557.08
  • SB-423562

    CAS:
    <p>SB-423562 is a calcium-sensing receptor (CaSR) antagonist and can be used in studies about osteoporosis.</p>
    Formula:C26H32N2O4
    Purezza:99.22%
    Colore e forma:Solid
    Peso molecolare:436.54
  • LSN3318839

    CAS:
    <p>LSN3318839 is a potent and orally available glucagon-like peptide-1 receptor (GLP-1R) modulator.LSN3318839 enhances GLP-1R G-protein-coupled signaling and can</p>
    Formula:C26H23Cl2N3O2
    Purezza:99.21%
    Colore e forma:Solid
    Peso molecolare:480.39
  • Rolapitant hydrochloride

    CAS:
    <p>Rolapitant HCl is a potent NK1 antagonist, non-CYP3A4 interactive, with anti-emetic effects and a Ki of 0.66 nM.</p>
    Formula:C25H27ClF6N2O2
    Purezza:98.35% - 99.79%
    Colore e forma:Solid
    Peso molecolare:536.94
  • Metipranolol hydrochloride

    CAS:
    <p>Metipranolol hydrochloride is a non-selective β-adrenergic receptor blocking agent.</p>
    Formula:C17H28ClNO4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:345.86

    Ref: TM-T16066

    1mg
    Fuori produzione
    2mg
    Fuori produzione
    Prodotto fuori produzione
  • Pumosetrag Hydrochloride

    CAS:
    <p>Pumosetrag Hydrochloride is an orally available 5-HT3 partial agonist. It is developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.</p>
    Formula:C15H18ClN3O2S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:339.84

    Ref: TM-T16683

    1mg
    Fuori produzione
    Prodotto fuori produzione
  • BIBP3226 TFA

    CAS:
    <p>BIBP3226 TFA is an effective and selective antagonist of neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor (Kis: 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF).</p>
    Formula:C29H32F3N5O5
    Colore e forma:Solid
    Peso molecolare:587.59

    Ref: TM-T10540

    1mg
    Fuori produzione
    Prodotto fuori produzione
  • Protease-Activated Receptor-4

    CAS:
    <p>Protease-Activated Receptor-4 (PAR4) is a proteinase-activated receptor-4 agonist used in antiplatelet therapy.</p>
    Formula:C33H46N8O7
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:666.77

    Ref: TM-T7380

    1mg
    Fuori produzione
    Prodotto fuori produzione
  • JMV 2959

    CAS:
    <p>JMV 2959 is an antagonist of growth hormone secretagogue receptor type 1a (GHS-R1a) (IC50: 32 nM).</p>
    Formula:C30H32N6O2
    Colore e forma:Solid
    Peso molecolare:508.61

    Ref: TM-T11719L

    1mg
    Fuori produzione
    2mg
    Fuori produzione
    Prodotto fuori produzione
  • (Rac)-Rotigotine hydrochloride

    CAS:
    <p>(Rac)-Rotigotine hydrochloride is a racemate of Rotigotine. Rotigotine is a full agonist of dopamine receptor, a partial the 5-HT1A receptor agonist.</p>
    Formula:C19H26ClNOS
    Colore e forma:Solid
    Peso molecolare:351.93

    Ref: TM-T12676

    1ml*10 (DMSO)
    Fuori produzione
    Prodotto fuori produzione
  • Arotinolol

    CAS:
    <p>Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radioligand [125I-ICYP] to [5HT1B-serotonergic] receptor sites. It is an antihypertensive agent.</p>
    Formula:C15H21N3O2S3
    Colore e forma:White Solid
    Peso molecolare:371.54

    Ref: TM-T10371

    1mg
    Fuori produzione
    Prodotto fuori produzione
  • 7-Desmethyl-agomelatine

    CAS:
    <p>7-Desmethyl-agomelatine, a metabolite of Agomelatine, exhibits lower activity than Agomelatine, which functions as a melatonergic (MT1 and MT2) agonist and 5-HT2C antagonist.</p>
    Formula:C14H15NO2
    Colore e forma:Solid
    Peso molecolare:229.27

    Ref: TM-T10193

    1mg
    Fuori produzione
    Prodotto fuori produzione
  • SR 146131

    CAS:
    <p>SR 146131 is a potent and selective agonist of the nonpeptide receptor.</p>
    Formula:C32H36ClN3O5S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:610.16

    Ref: TM-T16935

    1mg
    Fuori produzione
    Prodotto fuori produzione
  • CYM 9484

    CAS:
    <p>CYM 9484 is a selective and potent neuropeptide Y (NPY) Y2 receptor antagonist with an IC50 value of 19 nM.</p>
    Formula:C27H31N3O3S2
    Colore e forma:Solid
    Peso molecolare:509.68

    Ref: TM-T10921

    1mg
    Fuori produzione
    2mg
    Fuori produzione
    Prodotto fuori produzione
  • SB-399885 hydrochloride

    CAS:
    <p>SB-399885 hydrochloride is an antagonist of 5-HT6 receptor.</p>
    Formula:C18H22Cl3N3O4S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:482.81

    Ref: TM-T12843

    1mg
    Fuori produzione
    Prodotto fuori produzione
  • Beraprost sodium

    CAS:
    <p>Beraprost sodium is a stable and orally active prodrug of PGI2.</p>
    Formula:C24H29NaO5
    Colore e forma:Solid
    Peso molecolare:420.481

    Ref: TM-T13859

    1mg
    Fuori produzione
    Prodotto fuori produzione
  • ML-00253764 hydrochloride

    CAS:
    <p>ML-00253764 hydrochloride is an antagonist of nonpeptidic melanocortin receptor 4 (MC4R) (Ki and IC50 of 0.16 µM and 0.103 µM, respectively).</p>
    Formula:C18H19BrClFN2O
    Colore e forma:Solid
    Peso molecolare:413.71

    Ref: TM-T12072

    1mg
    Fuori produzione
    Prodotto fuori produzione
  • HOKU-81

    CAS:
    <p>HOKU-81is a new bronchodilator and is one of the metabolites of tulobuterol.</p>
    Formula:C12H18ClNO2
    Colore e forma:Solid
    Peso molecolare:243.73

    Ref: TM-T15498

    1mg
    Fuori produzione
    Prodotto fuori produzione
  • SHA 68

    CAS:
    <p>SHA 68 is a potent and selective non-peptide antagonist of neuropeptide S receptor (NPSR) with IC50 values of 22.0 nM for NPSR Asn107 and 23.8 nM for NPSR Ile107.</p>
    Formula:C26H24FN3O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:445.49

    Ref: TM-T12895

    1mg
    Fuori produzione
    Prodotto fuori produzione
  • ML-290

    CAS:
    <p>ML-290 is an effective relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes. It shows an EC50 of 94 nM.</p>
    Formula:C24H21F3N2O5S
    Colore e forma:Solid
    Peso molecolare:506.49

    Ref: TM-T16101

    1mg
    Fuori produzione
    Prodotto fuori produzione
  • TAK-683

    CAS:
    <p>TAK-683: a full KISS1R agonist, IC50=170 pM; a nonapeptide metastin analog with human EC50=0.96 nM, rat EC50=1.6 nM.</p>
    Formula:C64H83N17O13
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1298.45

    Ref: TM-TP2156L

    100mg
    Fuori produzione
    500mg
    Fuori produzione
    Prodotto fuori produzione
  • 3-Hydroxybenzylamine

    CAS:
    <p>3-Hydroxybenzylamine is a useful organic compound for research related to life sciences. The catalog number is T124305 and the CAS number is 73604-31-6.</p>
    Formula:C7H9NO
    Colore e forma:Solid
    Peso molecolare:123.155

    Ref: TM-T124305

    ne
    Fuori produzione
    Prodotto fuori produzione
  • Picumeterol

    CAS:
    <p>Picumeterol(GR 114297A) is a potent and selective β2 adrenergic receptor agonist. In vitro and in vivo trials, Picumeterol produced long-lasting airway smooth muscle relaxation. Picumeterol is a pure R enantiomer that can be used to improve lung function and reduce airway hyperreactivity in patients with asthma.</p>
    Formula:C21H29Cl2N3O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:426.38

    Ref: TM-T68129

    ne
    Fuori produzione
    Prodotto fuori produzione
  • TAK-448

    CAS:
    <p>TAK-448 (MVT-602), a potent KISS1R agonist, IC50: 460 pM, EC50: 632 pM, trialed for Prostate Cancer and Hypogonadism.</p>
    Formula:C58H80N16O14
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1225.36

    Ref: TM-TP1094

    1mg
    Fuori produzione
    5mg
    Fuori produzione
    Prodotto fuori produzione
  • dapitant

    CAS:
    <p>Dapitant, a non-peptide, selective antagonist of human NKI receptors, is representative of the 7,7,4-triarylperhydroisoindol-4-ols.</p>
    Formula:C37H39NO4
    Colore e forma:Solid
    Peso molecolare:561.71

    Ref: TM-T68049

    ne
    Fuori produzione
    Prodotto fuori produzione
  • 4-Hydroxypropranolol hydrochloride

    CAS:
    <p>4-Hydroxypropranolol hydrochloride is an active metabolite of Propranolol, with a potency comparable to Propranolol. It inhibits β1- and β2-adrenergic receptors (pA2s: 8.24 and 8.26).</p>
    Formula:C16H22ClNO3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:311.8

    Ref: TM-T10150

    100mg
    Fuori produzione
    500mg
    Fuori produzione
    Prodotto fuori produzione
  • Desmethyl cariprazine

    CAS:
    <p>Desmethyl cariprazine is a Cariprazine active metabolite. Cariprazine, an antipsychotic drug candidate, shows a high affinity for the D3 (Ki: 0.085 nM) and D2 (Ki: 0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (2.6 nM).</p>
    Formula:C20H30Cl2N4O
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:413.38

    Ref: TM-T15100

    100mg
    Fuori produzione
    500mg
    Fuori produzione
    Prodotto fuori produzione
  • BRL 15572

    CAS:
    <p>BRL 15572 is a useful organic compound for research related to life sciences. The catalog number is T64501 and the CAS number is 734517-40-9.</p>
    Formula:C25H27ClN2O
    Colore e forma:Solid
    Peso molecolare:406.95

    Ref: TM-T64501

    ne
    Fuori produzione
    Prodotto fuori produzione
  • 4-Hydroxyatomoxetine

    CAS:
    <p>4-Hydroxyatomoxetine, an active metabolite of Atomoxetine, is metabolized by CYP2D6. Atomoxetine is a noradrenaline reuptake inhibitor.</p>
    Formula:C17H21NO2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:271.35

    Ref: TM-T10145

    100mg
    Fuori produzione
    500mg
    Fuori produzione
    Prodotto fuori produzione
  • CRTh2 antagonist 3

    CAS:
    <p>CRTh2 antagonist 3, a potent molecule, activates PDK1 (EC50=2μM, Kd=8.4μM) and may cause cardiovascular inflammation.</p>
    Formula:C19H20N2O3S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:356.44

    Ref: TM-T10890

    100mg
    Fuori produzione
    500mg
    Fuori produzione
    Prodotto fuori produzione
  • Propiram fumarate HCl

    CAS:
    <p>Propiram fumarate HClis an orally available Opioid receptors agonist with analgesic activity for the study of musculoskeletal pain.</p>
    Formula:C16H25N3O·xClH
    Purezza:99.25%
    Colore e forma:Soild

    Ref: TM-T28453L

    1mg
    Fuori produzione
    5mg
    Fuori produzione
    10mg
    Fuori produzione
    25mg
    Fuori produzione
    50mg
    Fuori produzione
    100mg
    Fuori produzione
    500mg
    Fuori produzione
    Prodotto fuori produzione
  • Sarizotan

    CAS:
    <p>Sarizotan (EMD 128130) is an orally active compound that acts as an agonist for serotonin 5-HT 1A receptors and dopamine receptors, with IC50 values of 6.5 nM for rat 5-HT 1A, 0.1 nM for human 5-HT 1A, 15.1 nM for rat D 2, 17 nM for human D 2, 6.8 nM for human D 3, and 2.4 nM for human D 4.2.</p>
    Formula:C22H21FN2O
    Colore e forma:Solid
    Peso molecolare:348.421

    Ref: TM-T40439

    ne
    Fuori produzione
    Prodotto fuori produzione
  • 1-Oleoyl Lysophosphatidic Acid

    CAS:
    <p>1-Oleoyl Lysophosphatidic Acid (1-Oleoyl LPA) is a biologically active phospholipid that can be used to study cancer and atherosclerosis.</p>
    Formula:C21H41O7P
    Colore e forma:Solid
    Peso molecolare:436.52

    Ref: TM-T36907

    22.91mM*1
    Fuori produzione
    22.91mM*100
    Fuori produzione
    22.91mM*2.5
    Fuori produzione
    22.91mM*500
    Fuori produzione
    Prodotto fuori produzione
  • Patecibart

    CAS:
    <p>Patecibart is a humanized immunoglobulin G4-kappa monoclonal antibody that functions as an antagonist to the endothelin receptor A (EDNRA).</p>
    Purezza:98%
    Colore e forma:Liquid

    Ref: TM-T81538

    ne
    Fuori produzione
    1mg
    Fuori produzione
    5mg
    Fuori produzione
    50mg
    Fuori produzione
    Prodotto fuori produzione
  • (R)-(-)-α-Methylhistamine dihydrochloride

    CAS:
    <p>R(-)-alpha-Methylhistamine 2HCl is an effective and selective agonist of the H3 histamine receptor.</p>
    Formula:C6H13Cl2N3
    Colore e forma:Solid
    Peso molecolare:198.09

    Ref: TM-T24698

    ne
    Fuori produzione
    Prodotto fuori produzione
  • Vornorexant

    CAS:
    <p>Vornorexant (ORN-0829; TS-142) is a potent dual OX1R and OX2R antagonist with IC50 values of 1.05 nM and 1.27 nM, respectively. It exhibits potent sleep-promoting effects in vivo and can be used for insomnia treatment research.</p>
    Formula:C23H22FN7O2
    Colore e forma:Solid
    Peso molecolare:447.474

    Ref: TM-T39004

    ne
    Fuori produzione
    Prodotto fuori produzione
  • Amelubant

    CAS:
    <p>Amelubant (BIIL 284) is a prodrug of active metabolites BIIL 260 and BIIL 315 with anti-inflammatory activity[1]. It is a potent, oral, long-acting LTB4 receptor antagonist that negligibly binds to the LTB4 receptor, exhibiting Kis of 221 nM and 230 nM in vital cells and membranes.</p>
    Formula:C33H34N2O5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:538.63

    Ref: TM-T14210

    100mg
    Fuori produzione
    500mg
    Fuori produzione
    Prodotto fuori produzione
  • (Rac)-Zevaquenabant

    CAS:
    <p>(Rac)-Zevaquenabant ((Rac)-MRI-1867, compound 6b) is a potent and selective antagonist of cannabinoid receptor type 1 (CB1R) and inducible nitric oxide synthase (iNOS), with a binding affinity (Ki) of 5.7 nM for CB1R. It holds promise as an investigative tool in liver fibrosis research due to these characteristics.</p>
    Formula:C25H21ClF3N5O2S
    Colore e forma:Solid
    Peso molecolare:547.98

    Ref: TM-T39074

    ne
    Fuori produzione
    Prodotto fuori produzione
  • BX471 hydrochloride

    CAS:
    <p>BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with a Ki of 1 nM for human CCR1, exhibiting 250-fold selectivity over CCR2, CCR5, and CXCR4.</p>
    Formula:C21H25Cl2FN4O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:471.35

    Ref: TM-T14845

    ne
    Fuori produzione
    Prodotto fuori produzione
  • Canagliflozin-d4

    CAS:
    <p>Canagliflozin D4 is a deuterium-labeled Canagliflozin. Canagliflozin is an SGLT2 inhibitor.</p>
    Formula:C24H25FO5S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:448.54

    Ref: TM-T10669

    1mg
    Fuori produzione
    5mg
    Fuori produzione
    10mg
    Fuori produzione
    25mg
    Fuori produzione
    Prodotto fuori produzione
  • 2-Methyl-5-HT hydrochloride

    CAS:
    <p>2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.</p>
    Formula:C11H15ClN2O
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:226.7

    Ref: TM-T10075L2

    25mg
    Fuori produzione
    50mg
    Fuori produzione
    100mg
    Fuori produzione
    Prodotto fuori produzione
  • AM-2232

    CAS:
    <p>AM-2232 (UNII-40KCH8YIKP) is a potent and unselective agonist of the cannabinoid receptors.</p>
    Formula:C24H20N2O
    Purezza:99.37%
    Colore e forma:Solid
    Peso molecolare:352.43

    Ref: TM-T21450

    1mg
    Fuori produzione
    2mg
    Fuori produzione
    5mg
    Fuori produzione
    10mg
    Fuori produzione
    25mg
    Fuori produzione
    50mg
    Fuori produzione
    100mg
    Fuori produzione
    500mg
    Fuori produzione
    1ml*10 (DMSO)
    Fuori produzione
    1mL*10mM (DMSO)_old
    Fuori produzione
    Prodotto fuori produzione
  • Pamoic acid

    CAS:
    <p>Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.</p>
    Formula:C23H16O6
    Purezza:99.99%
    Colore e forma:Fine Yellow Powder
    Peso molecolare:388.37

    Ref: TM-T8353

    1g
    Fuori produzione
    1ml*10 (DMSO)
    Fuori produzione
    Prodotto fuori produzione
  • Flumexadol

    CAS:
    <p>Flumexadol is a selective 5-HT2C receptor agonist with an affinity (Ki) of 25 nM for the (+)-enantiomer and exhibits 40-fold selectivity over the 5-HT2A receptor. It is an orally active, non-narcotic analgesic.</p>
    Formula:C11H12F3NO
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:231.21

    Ref: TM-T11302

    50mg
    Fuori produzione
    100mg
    Fuori produzione
    Prodotto fuori produzione
  • Neurokinin antagonist 1

    CAS:
    <p>Neurokinin antagonist 1 is a potent is a neuropeptide antagonist that can be used to study neurological disorders.</p>
    Formula:C38H40N4O3
    Purezza:>99.99%
    Colore e forma:Solid
    Peso molecolare:600.75

    Ref: TM-T10056

    1mg
    Fuori produzione
    5mg
    Fuori produzione
    Prodotto fuori produzione
  • 2-Arachidonoylglycerol

    CAS:
    <p>In the central nervous system, 2-Arachidonoylglycerol is a second endogenous cannabinoid ligand</p>
    Formula:C23H38O4
    Purezza:95%
    Colore e forma:Liquid
    Peso molecolare:378.55

    Ref: TM-T14011

    5mg
    Fuori produzione
    26.4mM*100
    Fuori produzione
    Prodotto fuori produzione
  • MEN11467

    CAS:
    <p>MEN11467 is a novel, orally available, potent and selective peptidomimetic tachykinin NK 1 receptor antagonist for the study of acute colon cancer.</p>
    Formula:C38H40N4O3
    Purezza:>99.99%
    Colore e forma:Solid
    Peso molecolare:600.75

    Ref: TM-T12000

    1mg
    Fuori produzione
    5mg
    Fuori produzione
    Prodotto fuori produzione
  • Imetit dihydrobromide

    CAS:
    <p>Imetit dihydrobromide is a high affinity and effective agonist of histamine H3 and H4 receptors (Ki: 0.3 and 2.7 nM). Imetit mimics the histamine effect in triggering a shape change in eosinophils (EC50: 25 nM).</p>
    Formula:C6H12Br2N4S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:332.06

    Ref: TM-T15565

    50mg
    Fuori produzione
    100mg
    Fuori produzione
    Prodotto fuori produzione
  • GR 218,231

    CAS:
    <p>GR 218,231 is a selective antagonist of D3 dopamine receptor.</p>
    Formula:C24H33NO3S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:415.59

    Ref: TM-T27431

    25mg
    Fuori produzione
    50mg
    Fuori produzione
    100mg
    Fuori produzione
    Prodotto fuori produzione
  • AEF0117

    CAS:
    <p>AEF0117 is a signaling inhibitor of CB1-SSi that inhibits cannabinoid self-administration and can be used to study cannabis withdrawal.</p>
    Formula:C29H40O3
    Purezza:99.58%
    Colore e forma:Solid
    Peso molecolare:436.63

    Ref: TM-T79909

    ne
    Fuori produzione
    1mg
    Fuori produzione
    5mg
    Fuori produzione
    10mg
    Fuori produzione
    25mg
    Fuori produzione
    50mg
    Fuori produzione
    100mg
    Fuori produzione
    500mg
    Fuori produzione
    Prodotto fuori produzione
  • S1P1 agonist 6

    CAS:
    <p>Compound I (S1P1 agonist 6) is an S1P1 agonist that mitigates autoimmune activity by inhibiting lymphocyte trafficking and has potential as an immunosuppressive</p>
    Formula:C25H26F3NO3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:445.47

    Ref: TM-T79816

    ne
    Fuori produzione
    5mg
    Fuori produzione
    50mg
    Fuori produzione
    Prodotto fuori produzione
  • Dimethandrolone Undecanoate

    CAS:
    <p>Dimethandrolone Undecanoate (DMAU) is a novel orally available androgen with progestational activity and is a potential male contraceptive compound.</p>
    Formula:C31H50O3
    Purezza:99.65% - >99.99%
    Colore e forma:Solid
    Peso molecolare:470.73

    Ref: TM-T27176

    1mg
    Fuori produzione
    5mg
    Fuori produzione
    25mg
    Fuori produzione
    50mg
    Fuori produzione
    100mg
    Fuori produzione
    Prodotto fuori produzione
  • 2-MNG

    CAS:
    <p>2-MNG (2-Mercaptonicotinoyl glycine) is a novel melanogenesis inhibitor. 2-MNG inhibits two mechanisms of UV-induced skin pigmentation in vivo.</p>
    Formula:C8H8N2O3S
    Colore e forma:Liquid
    Peso molecolare:212.23

    Ref: TM-T89029

    1mg
    Fuori produzione
    5mg
    Fuori produzione
    10mg
    Fuori produzione
    25mg
    Fuori produzione
    50mg
    Fuori produzione
    100mg
    Fuori produzione
    1mL*10mM (DMSO)
    Fuori produzione
    Prodotto fuori produzione