Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(939 prodotti)
- Recettore dell'adenosina(242 prodotti)
- Recettore adrenergico(2.945 prodotti)
- Recettore della bombesina(30 prodotti)
- Recettore della bradichinina(59 prodotti)
- CXCR(148 prodotti)
- CaSR(32 prodotti)
- Recettore dei cannabinoidi(195 prodotti)
- Recettore della dopamina(407 prodotti)
- Recettore dell'endotelina(76 prodotti)
- Recettore GNRH(73 prodotti)
- GPCR19(31 prodotti)
- GRK(31 prodotti)
- GTPase(21 prodotti)
- Recettore del glucagone(165 prodotti)
- Proteina Hedgehog/Smoothened(44 prodotti)
- Recettore dell'istamina(358 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(24 prodotti)
- Recettore OX(40 prodotti)
- Recettore degli oppioidi(297 prodotti)
- PAFR(11 prodotti)
- PKA(48 prodotti)
- Recettore S1P(17 prodotti)
- SGLT(30 prodotti)
- Recettore Sigma(46 prodotti)
Mostrare 18 più sottocategorie
Trovati 5352 prodotti di "Proteina G/GPCR"
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2-O-Ethyl PAF C-16
CAS:<p>2-O-Ethyl PAF C-16, a homolog of Platelet-activating Factor (PAF) and competitive ligand for the Platelet-activating Factor Receptor (PAFR), inhibits the binding of PAF antagonist WEB 2086 to PAFR with an IC50 of 21 nM [1].</p>Formula:C26H56NO6PColore e forma:SolidPeso molecolare:509.709TASP0412098
CAS:<p>TASP0412098 is a potent, selective CRTH2 antagonist with oral activity.</p>Formula:C27H23ClN2O3Purezza:98%Colore e forma:SolidPeso molecolare:458.94Lidamidine
CAS:<p>Lidamidine (Lidamidinum) is an effective antidiarrheal agent that inhibits intestinal secretion, reduces intestinal transit, and inhibits smooth muscle</p>Formula:C11H16N4OPurezza:99.98%Colore e forma:SolidPeso molecolare:220.27UNC9994
CAS:<p>UNC9994 is a β-arrestin-biased dopamine D₂ receptor agonist (β-arrestin EC50 = 50 nM; Emax = 97%) with robust in vivo antipsychotic drug-like activities.</p>Formula:C21H22Cl2N2OSColore e forma:SolidPeso molecolare:421.38GLP-1R agonist 12
CAS:<p>GLP-1R agonist 12 (Compound 123) 是一种 GLP-1R 激动剂，能够用于研究糖尿病。</p>Formula:C34H36N6O4Colore e forma:SolidPeso molecolare:592.69AH13205
CAS:<p>AH13205 is an agonist of EP2 prostanoid receptor.</p>Formula:C24H36O4Purezza:98%Colore e forma:SolidPeso molecolare:388.54GLP-1R agonist 9
CAS:<p>GLP-1R agonist 9 acts as a GLP-1R agonist, demonstrating efficacy with EC50 values of 1.1 nM and 11 nM against CHO GLP-1R Clone H6 and Clone C6, respectively.</p>Formula:C32H30ClF2N3O5Colore e forma:SolidPeso molecolare:610.05AR-08
CAS:<p>AR-08 is a potent α2-adrenergic receptor agonist for the study of ADHD and attention deficit.</p>Formula:C12H12N6Purezza:99.7%Colore e forma:SolidPeso molecolare:240.26Encaleret
CAS:<p>Encaleret( JIT-305) is an antagonist of oral calcium-sensing receptor (CaSR), it is used for the treatment of osteoporosis.</p>Formula:C29H33ClFNO4Colore e forma:SolidPeso molecolare:514.03Foropafant
CAS:<p>Foropafant (SR27417) is a highly potent and selective platelet-activating factor (PAF) receptor antagonist (Ki: 57 pM).</p>Formula:C28H40N4SPurezza:99.67%Colore e forma:SolidPeso molecolare:464.71Casopitant mesylate
CAS:<p>Casopitant mesylate (GW679769B): Selective, brain-permeable NK1 receptor blocker, oral antiemetic.</p>Formula:C31H39F7N4O5SPurezza:98%Colore e forma:SolidPeso molecolare:712.7211(Z),14(Z)-Eicosadienoic acid
CAS:<p>11(Z),14(Z)-Eicosadienoic acid is an unsaturated fatty acid and metabolite that inhibits the binding of [3H]LTB4 to neutrophil modules (Ki=3 μm).</p>Formula:C20H36O2Purezza:99.94%Colore e forma:SolidPeso molecolare:308.5S1p receptor agonist 2
CAS:<p>S1P5-selective agonist; less so for S1P1/S1P3; useful for CNS disorders.</p>Formula:C24H23ClN2O4Colore e forma:SolidPeso molecolare:438.9Lazuvapagon
CAS:<p>Lazuvapagon is a vasopressin V2 receptor agonist that can be used to study enuresis.</p>Formula:C27H32N4O3Colore e forma:SolidPeso molecolare:460.57(2R,3S)-E1R
CAS:<p>(2R,3S)-E1R, an enantiomer of E1R, is a sigma-1 receptor modulator for treating cognitive disorders.</p>Formula:C13H16N2O2Purezza:98%Colore e forma:SolidPeso molecolare:232.28GSK2263167
CAS:<p>GSK2263167 is an agonist of S1P1 receptor.</p>Formula:C25H26N4O4Colore e forma:SolidPeso molecolare:446.5CB1 antagonist 1
CAS:<p>CB1 antagonist 1 is a CB1 receptor antagonist, used in the research of obesity and metabolic syndrome, neuroinflammatory disorders, cognitive disorders, and</p>Formula:C26H22Cl2N4Purezza:98%Colore e forma:SolidPeso molecolare:461.39NGD9002
CAS:<p>NGD9002 is a novel generation, topology 2 selective corticotropin releasing factor-1 (CRF-1) receptor antagonist agent.</p>Formula:C20H31N5OPurezza:98%Colore e forma:SolidPeso molecolare:357.49Prostaglandin D2 serinol amide
CAS:<p>Prostaglandin D2 serinol amide serves as a mild inhibitor against the hydrolysis of [3H]2-oleoylglycerol [1].</p>Formula:C23H39NO6Colore e forma:SolidPeso molecolare:425.566Bunazosin Hydrochloride
CAS:<p>Bunazosin Hydrochloride (E 1015) is an alpha(1)-adrenoceptor antagonist used as a systemic antihypertensive and an ocular hypotensive drug.</p>Formula:C19H28ClN5O3Purezza:99.12%Colore e forma:SolidPeso molecolare:409.91ACT 335827
CAS:<p>ACT-335827: oral, brain-penetrant OXR1 selective antagonist; IC50: 6 nM (OXR1), 417 nM (OXR2); for neurological research.</p>Formula:C31H38N2O5Colore e forma:SolidPeso molecolare:518.64BAY 73-1449
CAS:<p>BAY 73-1449 is a selective and potent antagonist of the prostacyclin receptor(IC50<0.1 nM).</p>Formula:C26H23N3O3Purezza:99.77%Colore e forma:SolidPeso molecolare:425.48LGD-6972 sodium
CAS:<p>LGD-6972 sodium is a glucagon receptor antagonist.</p>Formula:C43H46N2NaO5SPurezza:98%Colore e forma:SolidPeso molecolare:725.9PD-140548
CAS:<p>PD-140548 is a potent, CCKA receptor-selective antagonist.</p>Formula:C33H39N3O5Purezza:98%Colore e forma:SolidPeso molecolare:557.68Sulmazole
CAS:<p>Sulmazole (AR-L 115-BS) is a small molecule Sulmazole is a small molecule cGMP-PDE inhibitor.Sulmazole is a competitive inhibitor of A1 adenosine receptors.</p>Formula:C14H13N3O2SPurezza:99.94%Colore e forma:SolidPeso molecolare:287.34S1P5 receptor agonist-1
CAS:<p>S1P5 Receptor Agonist-1 (example 6) is a highly potent and selective agonist for the S1P5 receptor, exhibiting an EC50 value of 20 nM.</p>Formula:C20H24F3NO3Colore e forma:SolidPeso molecolare:383.4L-796568 free base
CAS:<p>L-796568 is a potent β3 agonist for obesity with 600x selectivity over β1/β2 receptors (EC50: 3.6 nM).</p>Formula:C31H27F3N4O3S2Colore e forma:SolidPeso molecolare:624.7INT-777 R-enantiomer
CAS:<p>INT-777 is the R-enantiomer of INT-777, less potent than INT-777,EC50 of 4.79 μM for TGR5.</p>Formula:C27H46O5Purezza:98%Colore e forma:SolidPeso molecolare:450.65Dihydrexidine
CAS:<p>Dihydrexidine is a full efficacy D1-like dopamine receptor (D1/D5) agonist (IC50: 10 nM for D1 receptor). It also shows potent antiparkinsonian activity.</p>Formula:C17H17NO2Purezza:98%Colore e forma:SolidPeso molecolare:267.32LM-1484
CAS:<p>LM-1484 displays a higher affinity for 3H-LTC4 sites and is an antagonist of CysLT1 receptor.</p>Formula:C28H24N4O3Purezza:98%Colore e forma:SolidPeso molecolare:464.52COR659
CAS:<p>COR659: suppresses alcohol/chocolate intake in rats; enhances GABAB receptor, blocks CB1 receptor.</p>Formula:C16H16ClNO3SPurezza:99.75%Colore e forma:SolidPeso molecolare:337.82Cipralisant maleate
CAS:<p>Cipralisant maleate is a potent, selective Histamine H3 receptor antagonist.</p>Formula:C18H24N2O4Colore e forma:SolidPeso molecolare:332.39TCS 2510
CAS:<p>TCS 2510 (CAY10598) 是一种选择性 PGE2 和 EP4 受体激动剂，可增强细胞内 cAMP 浓度和活性 β-caten 的丰度。TCS 2510 抑制TNF-α 产生，可用于研究代谢紊乱带来的疾病。</p>Formula:C21H29N5O2Purezza:98%Colore e forma:SolidPeso molecolare:383.49Ginkgolic acid 2-phosphate
CAS:<p>Ginkgolic acid 2-phosphate, a potent sphingosine 1-phosphate (S1P) agonist, induces ERK phosphorylation and interacts with S1P1 [1].</p>Formula:C22H37O6PColore e forma:SolidPeso molecolare:428.5RXFP1 receptor agonist-3
CAS:<p>RXFP1 receptor agonist-3 (Example 223) is an agonist of the RXFP1 receptor that inhibits cyclic AMP (cAMP) production in HEK293 cells stably expressing human</p>Formula:C42H34F9N3O5Colore e forma:SolidPeso molecolare:831.72Prostaglandin K2
CAS:<p>Prostaglandin K2 (PGK2), a 9,11-diketone derivative, results from PGE2 or PGD2 oxidation. Its biological presence remains speculative; however, it demonstrates resistance to in vitro metabolism by 15-hydroxy PGDH.</p>Formula:C20H30O5Colore e forma:SolidPeso molecolare:350.455Ono-RS 347
CAS:<p>Ono-RS 347 is a leukotriene antagonists with the activity of SRS-A antagonist.</p>Formula:C26H25N5O4Purezza:98%Colore e forma:SolidPeso molecolare:471.51Quinpirole dihydrochloride
CAS:<p>Quinpirole dihydrochloride is an agonist of the D2-like dopamine receptor.</p>Formula:C13H23Cl2N3Purezza:98%Colore e forma:SolidPeso molecolare:292.25PSB-SB1202
CAS:<p>PSB-SB1202 (Compound 21a), a phenyl coumarin compound, acts as a CB1/CB2 agonist. It demonstrates EC50 values of 56 and 14 nM and K i values of 32 and 49 nM for CB1 and CB2 receptors, respectively [1].</p>Formula:C23H26O4Colore e forma:SolidPeso molecolare:366.454-hydroxy Nebivolol hydrochloride
CAS:<p>4-Hydroxy Nebivolol, a primary metabolite of Nebivolol, results from the enzymatic hydroxylation of Nebivolol by the cytochrome P450 (CYP) isoform CYP2D6.</p>Formula:C22H25F2NO5HClColore e forma:SolidPeso molecolare:457.9(S)-Bexicaserin
CAS:<p>(S)-Bexcaserin (compound 2) serves as a 5-HT2C receptor agonist, presenting research possibilities in obesity and psychiatric disorders [1].</p>Formula:C15H19F2N3OPurezza:98%Colore e forma:SolidPeso molecolare:295.33Tradipitant
CAS:<p>Tradipitant (VLY-686) is an antagonist of neurokinin-1.</p>Formula:C28H16ClF6N5OPurezza:99.42%Colore e forma:SolidPeso molecolare:587.9Vatinoxan hydrochloride
CAS:<p>Vatinoxan hydrochloride is an antagonist of the peripheral α2 adrenergic receptors.</p>Formula:C20H27ClN4O4SPurezza:98%Colore e forma:SolidPeso molecolare:454.97Ebrotidine
CAS:<p>Ebrotidine (FI3542) is a competitive H2-receptor antagonist with Ki of 127.5 nM. Ebrotidine has a potent antisecretory activity and evidenced gastroprotection.</p>Formula:C14H17BrN6O2S3Purezza:97.519%Colore e forma:SolidPeso molecolare:477.42L 691678
CAS:<p>L 691678 is a potent leukotriene biosynthesis inhibitor.</p>Formula:C36H30IN5O5SPurezza:98%Colore e forma:SolidPeso molecolare:771.63Tedalinab
CAS:<p>Tedalinab is an effective and selective cannabinoid receptor 2 agonist.</p>Formula:C19H21F2N3OPurezza:98%Colore e forma:SolidPeso molecolare:345.39DCOIT
CAS:<p>DCOIT, an isothiazolinone derivative, stimulates the synthesis of follicle-stimulating hormone and luteinizing hormone in the brain by activating the gonadotropin-releasing hormone receptor (GnRHR). Additionally, it interferes with G protein-coupled receptors, MAPK, and Ca 2+ signaling pathways [1].</p>Formula:C11H17Cl2NOSColore e forma:SolidPeso molecolare:282.22Brilaroxazine
CAS:<p>Brilaroxazine (RP5063): multimodal dopamine/5-HT modulator, partial agonist at D2/D3/D4, 5-HT1A/2A, and antagonist at 5-HT2B/7.</p>Formula:C22H25Cl2N3O3Purezza:99.36%Colore e forma:SolidPeso molecolare:450.36H3 receptor antagonist 1
CAS:<p>H3 receptor antagonist 1 is used in the study of neurological diseases, histamine H3 receptor antagonist.</p>Formula:C20H28F2N2OPurezza:98%Colore e forma:SolidPeso molecolare:350.45Dansyl-NECA
CAS:<p>Dansyl-NECA is a selective agonist of fluorescent adenosine A1 receptor.</p>Formula:C30H40N8O6SColore e forma:SolidPeso molecolare:640.75CP 154,526
CAS:<p>CP 154,526 is a selective CRF1 receptor antagonist (Ki = 2.7 nM). CP 154,526 blocks CRF-induced activation of adenylate cyclase and the HPA axis.</p>Formula:C23H32N4Colore e forma:SolidPeso molecolare:364.53SDZ-NVI-085
CAS:<p>SDZ-NVI-085 is an α1 adrenergic receptor agonist and a competitive antagonist of 5-hydroxytryptamine.</p>Formula:C15H21NO2SColore e forma:SolidPeso molecolare:279.4GT-2331
CAS:<p>GT-2331 is a histamine H3 receptor antagonist.</p>Formula:C14H20N2Colore e forma:SolidPeso molecolare:216.32AJ-76 hydrochloride
CAS:<p>AJ-76 hydrochloride ((+)-AJ 76 hydrochloride) serves as a dopamine autoreceptor antagonist, exhibiting pK i values of 6.95 for hD3, 6.67 for hD4, 6.37 for hD2S, 6.21 for hD2L, and 6.07 for rD2 receptors, indicating its binding affinity strength across these receptor types.</p>Formula:C15H24ClNOColore e forma:SolidPeso molecolare:269.81Fiboflapon sodium
CAS:<p>Fiboflapon sodium, an oral 5-LOX-activating protein inhibitor, binds FLAP at 2.9 nM, inhibits LTB4 at 76 nM.</p>Formula:C38H43N3NaO4SColore e forma:SolidPeso molecolare:660.83Aganepag isopropyl
CAS:<p>Aganepag isopropyl can be used to treat Glaucoma.</p>Formula:C27H37NO4SColore e forma:SolidPeso molecolare:471.65R-96544
CAS:<p>R-96544 is an orally active antagonist of the 5-HT2A receptor that has demonstrated the ability to inhibit platelet aggregation in vitro [1].</p>Formula:C22H30ClNO3Colore e forma:SolidPeso molecolare:391.93GLP-1 receptor agonist 3
CAS:<p>GLP-1 receptor agonist 3 is a GLP-1 receptor agonist,Example 4A-1, has EC50s of 1.1 nM and 13 nM in Clone H6 and Clone C6 cell lines assay, respectively.</p>Formula:C31H30FN5O4Purezza:98%Colore e forma:SolidPeso molecolare:555.6ACT-209905
CAS:<p>ACT-209905 is an agonist of S1P1 receptor.</p>Formula:C26H35N5O5Purezza:98%Colore e forma:SolidPeso molecolare:497.59PSB-1901 free base
CAS:<p>PSB-1901: potent A2B Adenosine Receptor Antagonist; Ki=0.0835 nM; >10,000x selective; effective in mice for preclinical studies.</p>Formula:C24H25BrN6O4SColore e forma:SolidPeso molecolare:573.465-HT3 antagonist 1
CAS:<p>5-HT3 antagonist 1 is a potent and selective antagonist of 5-HT3 receptor.</p>Formula:C22H27N5OPurezza:98%Colore e forma:SolidPeso molecolare:377.48FTY720 (S)-Phosphate
CAS:<p>FTY720 (S)-Phosphate is an active FTY720 derivative modulating S1P receptors, preventing lymphocyte egress, enhancing barrier integrity, aiding immune research.</p>Formula:C19H34NO5PPurezza:99.37%Colore e forma:SolidPeso molecolare:387.45APJ receptor agonist 5
CAS:<p>Potent oral APJ agonist (EC 50:0.4 nM); improves cardiac function in HF, with good pharmacokinetics and safety.</p>Formula:C26H29N3O6Colore e forma:SolidPeso molecolare:479.52ZINC49534341
CAS:<p>ZINC49534341 is a potent MRGPRX2 antagonist, exhibiting a K_i (inhibition constant) of 32 nM [1].</p>Formula:C12H9N3OS2Colore e forma:SolidPeso molecolare:275.35BIM-23056 TFA
CAS:<p>BIM 23056 TFA, a potent linear octapeptide antagonist of sst3 and sst5 somatostatin receptors, exhibits inhibition constants (K_i) of 10.8 for sst3 and 5.7 for</p>Formula:C73H82F3N11O11Colore e forma:SolidPeso molecolare:1346.49I-287
CAS:<p>I-287 is a selective, orally active PAR2 inhibitor that functions as a negative allosteric modulator of Gαq and Gα12/13 activity and their downstream effectors.</p>Formula:C30H30ClFN4O4Colore e forma:SolidPeso molecolare:565.0411-keto Fluprostenol
CAS:<p>11-Keto Fluprostenol, a potent analog of prostaglandin F2α (PGF2α), primarily interacts with the FP receptor. It is a structurally modified derivative of prostaglandin D2 (PGD2) designed to enhance its potency and extend its half-life. The compound is produced by oxidizing fluprostenol at the C-11 position, which results in 11-keto fluprostenol. This modification allows 11-keto Fluprostenol to exhibit moderate affinity for the CRTH2/DP2 receptor, though it shows negligible activity at the DP1 receptor, distinguishing its action from that of PGD2.</p>Formula:C23H27F3O6Colore e forma:SolidPeso molecolare:456.458PD 168368
CAS:<p>PD 168368 is a mixed neuromodulin B receptor (NMB-R) antagonist and potent FPR1/FPR2/FPR3 agonist that inhibits the gastrin-releasing peptide receptor.</p>Formula:C31H34N6O4Purezza:98.44%Colore e forma:SolidPeso molecolare:554.64FAUC-312
CAS:<p>FAUC-312 is a potent and selective agonist of the dopamine D4 receptor.</p>Formula:C21H26N4Purezza:98%Colore e forma:SolidPeso molecolare:334.462-Chloro-ATP
CAS:2-Chloro-ATP is a soluble inhibitor of guanylate cyclase (guanylate cyclase) that can increase intracellular calcium ion concentrations at low concentrations through a mechanism independent of inositol phosphate production.Formula:C10H15ClN5O13P3Colore e forma:SolidPeso molecolare:541.63AGN-191129
CAS:<p>AGN-191129 (PGF2α-OMe) is a PGF2α analog with C-1 carboxyl replaced by O-methyl; it lowers eye pressure, but its receptors are unclear.</p>Formula:C21H38O4Colore e forma:SolidPeso molecolare:354.52JNJ-37822681 dihydrochloride
CAS:<p>JNJ-37822681 dihydrochloride 是特异性的、有中枢活性的，可快速解离的多巴胺 D2受体拮抗剂，与多巴胺 D2L 受体结合的亲和力适中 (Ki=158 nM)。JNJ-37822681 dihydrochloride 在精神分裂症和躁郁症领域有研究价值。</p>Formula:C17H19Cl2F5N4Purezza:99.78%Colore e forma:SolidPeso molecolare:445.26T 98475
CAS:<p>gonadotropin-releasing hormone (GnRH, LHRH) receptor antagonist,orally active</p>Formula:C37H37F2N3O4SPurezza:98%Colore e forma:SolidPeso molecolare:657.77[D-Ala6]-LH-RH
CAS:<p>[D-Ala6]-LH-RH, a Luteinizing-hormone-releasing hormone (LHRH) analogue, functions as a gonadotropin-releasing hormone (GnRH) receptor agonist [1].</p>Formula:C56H77N17O13Colore e forma:SolidPeso molecolare:1196.32GSK1842799
CAS:<p>GSK1842799 is a selective S1P1 receptor agonist with good oral bioavailability.</p>Formula:C24H30F9N3O6SColore e forma:SolidPeso molecolare:659.56(Rac)-Modipafant
CAS:<p>(Rac)-Modipafantis a PAFR antagonist that inhibits PAF-induced aggregation of washed platelets in rabbits.</p>Formula:C34H29ClN6O3Purezza:97.96% - 98.09%Colore e forma:SolidPeso molecolare:605.09TRAP-6-IN-1
CAS:<p>TRAP-6-IN-1 inhibits collagen/TRAP-6, IC50: 17.12/11.88 μM, blocks platelet aggregation.</p>Formula:C18H20O3Colore e forma:SolidPeso molecolare:284.35Dibenamine hydrochloride
CAS:<p>Dibenamine hydrochloride is a competitive and irreversible blocking agent of the β-adrenergic receptor.</p>Formula:C16H19Cl2NPurezza:96.43%Colore e forma:Oily Liquid SolidPeso molecolare:296.23BMS-763534
CAS:<p>BMS-763534 is a potent antagonist of corticotropin-releasing factor/hormone receptor 1 (CRHR-1).</p>Formula:C18H21ClF2N4O3Colore e forma:SolidPeso molecolare:414.83YM543 free base
CAS:<p>"YM543 is an effective, oral SGLT2 inhibitor that lowers blood glucose, useful for diabetes research."</p>Formula:C23H24O6Colore e forma:SolidPeso molecolare:396.43Tachykinin angatonist 1
CAS:<p>Tachykinin antagonist 1 is an antagonist of neurokinin receptors.</p>Formula:C24H35Cl2N5O3SPurezza:98%Colore e forma:SolidPeso molecolare:544.54GSK-554418A
CAS:<p>GSK-554418A, a novel azaindole CB(2) agonists, is used for the treatment of chronic pain. It is efficacious in the acute model and the chronic joint pain model.</p>Formula:C19H19ClN4O2Colore e forma:SolidPeso molecolare:370.839-keto Fluprostenol
CAS:<p>9-Keto Fluprostenol, a potent analog of prostaglandin E2 (PGE2), features structural modifications aimed at enhancing its half-life and potency. It derives from Fluprostenol, a thoroughly researched, potent analog of PGF2α, primarily interacting with the FP receptor. The creation of 9-Keto Fluprostenol through the oxidation at C-9 of Fluprostenol suggests a high affinity for EP receptors, potentially functioning as a PGE2 agonist.</p>Formula:C23H27F3O6Colore e forma:SolidPeso molecolare:456.458Siramesine Fumarate
CAS:<p>Siramesine Fumarate, a sigma receptor agonist, is used potentially for the treatment of generalized anxiety disorder.</p>Formula:C34H35FN2O5Purezza:98%Colore e forma:SolidPeso molecolare:570.65SSTR5 antagonist 1
CAS:<p>SSTR5 antagonist 1: selective, oral SSTR5 blocker; IC50: 9.6 nM (human), 57 nM (mouse).</p>Formula:C28H34FN3O5Purezza:98%Colore e forma:SolidPeso molecolare:511.59(S)-Renzapride
<p>(S)-Renzapride (BRL 24924), 5-HT4 agonist (Ki 115 nM), 5HT2b/5HT3 antagonist, for C-IBS study.</p>Formula:C16H22ClN3O2Colore e forma:SolidPeso molecolare:323.82(±)-Fabesetron hydrochloride
CAS:<p>FK1052 hydrochloride is a potent 5-HT3 and 5-HT4 receptor dual antagonist.</p>Formula:C18H20ClN3OPurezza:98%Colore e forma:SolidPeso molecolare:329.82CB-52
CAS:<p>CB-52 acts as a neutral antagonist and ligand for the CB2 cannabinoid receptor [1].</p>Formula:C26H43NO3Colore e forma:SolidPeso molecolare:417.62S1R agonist 1 hydrochloride
CAS:<p>S1R Agonist 1 (Compound 6b) hydrochloride is a selective S1R agonist, displaying K i values of 0.93 nM for S1R and 72 nM for S2R, and has demonstrated</p>Formula:C20H26ClNOPurezza:98%Colore e forma:SolidPeso molecolare:331.88ONO-2050297
CAS:<p>ONO-2050297 is the first potent dual CysLT1 and CysLT2 antagonist with IC50 values of 0.017 μM (CysLT1) and 0.00087 μM (CysLT2), respectively.</p>Formula:C31H34N2O7Colore e forma:SolidPeso molecolare:546.61Satigrel
CAS:<p>Satigrel is a new antiplatelet agent. It also inhibits platelet accumulation in prosthetic arterial grafts.</p>Formula:C20H19NO4Purezza:98%Colore e forma:SolidPeso molecolare:337.37GLP-1R agonist 10
CAS:<p>GLP-1R agonist 10 is a GLP-1 agonist (EC50: 0.051 nM).</p>Formula:C29H29ClFN5O4Colore e forma:SolidPeso molecolare:566.02SLIGRL-NH2 TFA
CAS:<p>SLIGRL-NH2 TFA, also known as Protease-Activated Receptor-2 Activating Peptide TFA, is a Protease-Activated Receptor-2 (PAR-2) agonist [1].</p>Formula:C31H57F3N10O9Colore e forma:SolidPeso molecolare:770.84CYM50260
CAS:<p>CYM50260 is a potent and exquisitely selective agonist of sphingosine-1-phosphate 4 receptor (S1P4-R, EC50= nM) with no activity against S1P1-R, S1P2-R, S1P3-R</p>Formula:C14H11Cl3FNO2Purezza:99.88%Colore e forma:SolidPeso molecolare:350.6Dothiepin
CAS:<p>Dothiepin (Dosulepin; Dothep), an antidepressant with sedative/anxiolytic properties, preferentially inhibits noradrenaline over serotonin uptake, enhancing</p>Formula:C19H21NSPurezza:98%Colore e forma:SolidPeso molecolare:295.44Phentolamine Analogue 1
CAS:<p>Phentolamine Analogue 1 is an analogue of phentolamine. Phentolamine is a nonselective antagonist of α-adrenergic.</p>Formula:C17H19N3OPurezza:99.96%Colore e forma:SolidPeso molecolare:281.35Quinotolast sodium
CAS:<p>Quinotolast sodium inhibits histamine, LTC4 and PGD2 release in a concentration-dependent manner in the concentration range of 1-100 μg/mL.</p>Formula:C17H12N6NaO3Purezza:98%Colore e forma:SolidPeso molecolare:371.312URB447
CAS:<p>URB447, a peripherally restricted CB1 cannabinoid antagonist with IC50 values of 313 nM for rat CB1 receptor and 41 nM for human CB2 receptor, effectively reduces food intake and body weight gain in mice. It achieves these effects without penetrating the brain or antagonizing central CB1-dependent responses, making it a potential research tool for obesity studies [1].</p>Formula:C25H21ClN2OColore e forma:SolidPeso molecolare:400.9SKF 81297 hydrobromide
CAS:<p>SKF 81297 hydrobromide, a selective agonist of the dopamine D1-like receptor，exhibits central activity and is widely used to study the neuromodulatory effects.</p>Formula:C16H17BrClNO2Purezza:99.52%Colore e forma:SolidPeso molecolare:370.67Sigma-1 receptor antagonist 3
CAS:<p>Sigma-1 receptor antagonist 3 is a more potent and selective antagonist of Sigma-1 (σ1) receptor (Ki = 1.14 nM) than σ2 receptor(Ki = 1239 nM).</p>Formula:C19H23ClFN3OPurezza:99.95%Colore e forma:SolidPeso molecolare:363.86AZD2423
CAS:<p>AZD2423 is a potent, selective, orally bioavailable, and non-competitive CCR2 chemokine receptor negative allosteric modulator and it has an IC50 of 1.2 nM for</p>Formula:C20H29ClFN5O2Purezza:98%Colore e forma:SolidPeso molecolare:425.935-HT2C agonist-3
CAS:<p>5-HT2C agonist-3 ((+)-19), a selective 5-HT2C agonist (EC 50: 24 nM, Ki: 78 nM), exhibits antipsychotic-like activity by blocking amphetamine-induced</p>Formula:C19H23ClFNO2Purezza:98%Colore e forma:SolidPeso molecolare:351.84PF-04634817
CAS:<p>PF-0463481: safe, well-tolerated, dual CCR2/CCR5 antagonist for diabetic nephropathy; similar human/rodent CCR2 potency, less rodent CCR5 effect.</p>Formula:C25H36F3N5O3Purezza:98%Colore e forma:SolidPeso molecolare:511.58Osemozotan Free Base
CAS:<p>Osemozotan Free Base is a 5-HT(1A) receptor agonist.</p>Formula:C19H21NO5Colore e forma:SolidPeso molecolare:343.372-Thio-UTP tetrasodium
CAS:<p>2-Thio-UTP tetrasodium, a potent agonist for P2Y2, P2Y4, and P2Y6 receptors, serves as a crucial compound in cancer research [1].</p>Formula:C9H11N2Na4O14P3SColore e forma:SolidPeso molecolare:588.13IIIM-8
CAS:<p>IIIM-8 is a melanogenesis inhibitor that suppresses pigment production in both in vitro and in vivo settings, exhibiting no cytotoxic effects on Human Adult</p>Formula:C14H17NO4Purezza:98%Colore e forma:SolidPeso molecolare:263.29GSA-10
CAS:<p>GSA-10 is a potent Smoothened (Smo) receptor agonist with an EC50 of 1.2 μM.</p>Formula:C26H30N2O5Purezza:99.71%Colore e forma:SolidPeso molecolare:450.53PSB-1115 potassium salt
CAS:<p>PSB-1115 potassium salt, a selective A2B Adenosine Receptor antagonist, inhibits the 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced contraction inhibition of acetylcholine (ACh) [1].</p>Formula:C14H13KN4O5SColore e forma:SolidPeso molecolare:388.44(2S,3S)-E1R
CAS:<p>(2R,3R)-E1R is a sigma-1 receptor modulator for cognitive/memory disorder treatment.</p>Formula:C13H16N2O2Purezza:98%Colore e forma:SolidPeso molecolare:232.285-HT2 agonist-1
CAS:<p>Compound 24, a 5-HT2 agonist-1, selectively activates 5-HT2A, 5-HT2B, and 5-HT2C receptors with IC50 values of 10 nM, 8.3 nM, and 1.6 nM, respectively.</p>Formula:C19H23ClN2O2Purezza:98%Colore e forma:SolidPeso molecolare:346.85Prostaglandin F2α serinol amide
CAS:<p>Prostaglandin F2α serinol amide, a serinolamide G protein-coupled receptor, elevates calcium levels in human non-small cell lung cancer cells. Additionally, Prostaglandin F2α functions as a luteinizing hormone in sheep and potentially serves as a nociceptive mediator in the spinal cord [1] [2] [3].</p>Formula:C23H41NO6Colore e forma:SolidPeso molecolare:427.582CB2R-IN-1
CAS:<p>CB2R-IN-1 is a potent inverse agonist of the cannabinoid CB2 receptor (Ki: 0.9 nM).</p>Formula:C23H27F3N4O6S3Purezza:98%Colore e forma:SolidPeso molecolare:608.67Celiprolol hydrochloride
CAS:Celiprolol hydrochloride (Selectrol) is a cardioselective beta-1 adrenergic antagonist that has intrinsic sympathomimetic activity.Formula:C20H33N3O4·HClColore e forma:White Crystalline SolidPeso molecolare:415.96CCR2 antagonist 4
CAS:<p>CCR2 antagonist 4 (Teijin compound 1) is a potent and specific antagonist of CCR2(IC50s of 180 nM), and potently inhibits MCP-1-induced chemotaxis(IC50 of 24 nM</p>Formula:C21H21ClF3N3O2Purezza:99.86%Colore e forma:SolidPeso molecolare:439.86BVFP
CAS:<p>BVFP is a PGRN-SORT1 inhibitor/SORT1 antagonist that binds to key residues 588-593 of PGRN,blocking PGRN-SORT1 binding and having potential for FTLD-TDP.</p>Formula:C13H8BrF3N2OPurezza:98.74%Colore e forma:SolidPeso molecolare:345.12CaSR antagonist-1
CAS:<p>CaSR Antagonist-1 is a potent inhibitor of the calcium-sensing receptor (CaSR) with an inhibitory concentration (IC50) of 50 nM, suitable for the investigation</p>Formula:C29H24FN3O2SPurezza:98%Colore e forma:SolidPeso molecolare:497.58(S)-FTY720-phosphonate
CAS:<p>FTY720 (S)-Phosphate, an S1P receptor 1 (S1PR1) agonist, is utilized in studying acute inflammatory diseases, including acute lung injury.</p>Formula:C20H36NO4PPurezza:98%Colore e forma:SolidPeso molecolare:385.48CB-25
CAS:<p>CB-25 is a partial agonist ligand of CB1 cannabinoid receptors, augmenting Forskolin-induced cAMP formation in cancer cells, though not affecting hCB1-CHO cells</p>Formula:C25H41NO3Purezza:98%Colore e forma:SolidPeso molecolare:403.6Droxicam
CAS:<p>Droxicam (Droxicamum) is a non-steroidal anti-inflammatory compound and can be used for research on the relief of inflammation and pain in musculoskeletal</p>Formula:C16H11N3O5SPurezza:99.04%Colore e forma:SolidPeso molecolare:357.34L-736380
CAS:<p>L-736380, a CCK-B antagonist, reduces gastric acid (ID50: 0.064mg/kg) and blocks [(125)I]CCK-8S in mouse brains (ED50: 1.7mg/kg).</p>Formula:C25H29N9O2Colore e forma:SolidPeso molecolare:487.56Hedgehog IN-2
CAS:<p>Hedgehog IN-2 (Compound 20) functions as an inhibitor of the Hedgehog signaling pathway, exhibiting an IC50 of <0.003 μM in C3H10T1/2 cells [1].</p>Formula:C24H22N4O2Colore e forma:SolidPeso molecolare:398.46Domesticine, (-)-
CAS:<p>Domesticine, (-)- is an antagonist of alpha-1D-adrenoceptor.</p>Formula:C19H19NO4Purezza:98%Colore e forma:SolidPeso molecolare:325.36FR-181877
CAS:<p>FR-181877: nonprostanoid PGI2 agonist, ADP-induced platelet aggregation inhibitor (IC50=0.081μM), orally bioavailable (56%), long half-life (4.3h) in rats.</p>Formula:C30H28N2O4Purezza:98%Colore e forma:SolidPeso molecolare:480.55(+)-Fluprostenol
CAS:<p>(+)-Fluprostenol (AL-5848), an analogue of prostaglandin F2 alpha, is a prostaglandin F2α receptor PTGFR agonist and decreases the expression of Oviductal</p>Formula:C23H29F3O6Purezza:97.35%Colore e forma:SolidPeso molecolare:458.47BLT2 antagonist-1
CAS:<p>BLT2 antagonist-1 (compound 15b) is a selective inhibitor of the BLT2 receptor, impeding the chemotaxis of CHO-BLT2 cells at an IC50 of 224 nM, while not</p>Formula:C26H26FNO4Purezza:98%Colore e forma:SolidPeso molecolare:435.49LTB4 antagonist 1
CAS:<p>LTB4 Antagonist 1, a carboxamide-acid derivative, potently inhibits Leukotriene B4 (LTB4) activity with an IC50 value of 288 nM and exhibits notable anti-</p>Formula:C26H23NO6Purezza:98%Colore e forma:SolidPeso molecolare:445.46Isopropyl dodec-11-enylfluorophosphonate
CAS:<p>Isopropyl dodec-11-enylfluorophosphonate (IDEFP) is an organophosphorus ester functioning as a central cannabinoid receptor (CB1) antagonist and exhibits</p>Formula:C15H30FO2PPurezza:98%Colore e forma:SolidPeso molecolare:292.37TG6-129
CAS:<p>TG6-129 is an EP2 receptor antagonist, blocking PGE2 effects, reducing inflammatory markers with 1.6 µM IC50.</p>Formula:C20H18FN5O3S3Purezza:99.55%Colore e forma:SolidPeso molecolare:491.5817-Phenyl trinor prostaglandin A2
CAS:<p>17-Phenyl trinor prostaglandin A2 is a synthetic analog of prostaglandin [1].</p>Formula:C23H28O4Colore e forma:SolidPeso molecolare:368.473BMS-639623
CAS:<p>BMS-639623 is a CCR3 antagonist with a picomolar inhibitory effect on eosinophilic chemotaxis and can be used in the treatment of asthma.</p>Formula:C25H32FN7O2Colore e forma:SolidPeso molecolare:481.57RS 17053 hydrochloride
CAS:<p>RS 17053 hydrochloride: selective α1A adrenoceptor antagonist, pKi 9.1, pA2 9.8.</p>Formula:C24H30Cl2N2O2Purezza:99.27%Colore e forma:SolidPeso molecolare:449.41NNC 26-9100
CAS:<p>Somatostatin sst4 receptor agonist</p>Formula:C22H25BrCl2N6SPurezza:98%Colore e forma:SolidPeso molecolare:556.35BMS-764459
CAS:<p>BMS-764459 is a potent antagonist of corticotropin-releasing factor/hormone receptor 1 (CRHR-1).</p>Formula:C19H21F2N5O3Colore e forma:SolidPeso molecolare:405.4Bufuralol (hydrochloride)
CAS:<p>Bufuralol hydrochloride is a potent, non-selective, orally active β-blocker with partial agonist effects and a CYP2D6 probe.</p>Formula:C16H24ClNO2Colore e forma:SolidPeso molecolare:297.82MRS3558
CAS:<p>MRS3558 is an agonist of A3 adenosine receptors.</p>Formula:C20H20Cl2N6O3Colore e forma:SolidPeso molecolare:463.32VKGILS-NH2 TFA
CAS:<p>VKGILS-NH2 TFA, a non-impacting control peptide for PAR2 agonist SLIGKV-NH2, doesn't affect DNA synthesis.</p>Formula:C30H55F3N8O9Colore e forma:SolidPeso molecolare:728.8PNU109291
CAS:<p>PNU109291, a potent and selective agonist of the 5-HT1D receptor, effectively mitigates dural plasma extravasation induced by trigeminal ganglion stimulation.</p>Formula:C24H31N3O3Purezza:98%Colore e forma:SolidPeso molecolare:409.52CCR4 antagonist 4
CAS:<p>CCR4 Antagonist 4 (Compound 22) is a potent and selective antagonist of the CC chemokine receptor-4 (CCR4), displaying an IC50 value of 0.02 μM. It also inhibits MDC-mediated chemotaxis and Ca2+ mobilization, with IC50 values of 0.007 μM and 0.003 μM, respectively. This compound is utilized in research on allergic inflammation [1].</p>Formula:C24H27Cl2N7OColore e forma:SolidPeso molecolare:500.42EP4 receptor agonist 2
CAS:<p>EP4 receptor agonist 2 (compound 31) is a potent EP4 receptor agonist, demonstrating an EC50 value of 0.8 nM and K_i values of >100,000, 38,000, and 3.1 nM for the EP2, EP3, and EP4 receptors, respectively [1].</p>Formula:C27H32ClNO4Colore e forma:SolidPeso molecolare:470.01Fiboflapon
CAS:<p>Fiboflapon (GSK2190915), an oral 5-lipoxygenase inhibitor, binds FLAP at 2.9 nM, inhibits LTB4 with 76 nM IC50.</p>Formula:C38H43N3O4SPurezza:97.01%Colore e forma:SolidPeso molecolare:637.83Indeloxazine hydrochloride
CAS:<p>Indeloxazine HCl: Serotonin releaser, NE reuptake inhibitor, NMDA antagonist; antidepressant that boosts acetylcholine in rats.</p>Formula:C14H18ClNO2Purezza:98%Colore e forma:SolidPeso molecolare:267.75O-2050
CAS:<p>O-2050: strong CB1 antagonist (Ki 2.5 nM), CB2 inhibitor (Ki 0.2 nM); reduces mouse food intake, increases activity.</p>Formula:C23H31NO4SPurezza:98%Colore e forma:SolidPeso molecolare:417.56NBI-35965
CAS:<p>NBI-35965 is a CRF1 receptor antagonist.</p>Formula:C21H22Cl2N4Colore e forma:SolidPeso molecolare:401.33PF-02575799
CAS:<p>PF-02575799 is an inhibitor of microsomal triglyceride transfer protein (MTP) (IC50: 0.77±0.29 nM).</p>Formula:C42H37FN4O4Purezza:98%Colore e forma:SolidPeso molecolare:680.77Abediterol
CAS:<p>Abediterol (LAS100977): potent, long-acting beta-2 agonist for asthma and COPD treatment.</p>Formula:C25H30F2N2O4Colore e forma:SolidPeso molecolare:460.51L 163255
CAS:<p>L 163255 is a type of growth hormone secretagogue (GHS).</p>Formula:C28H38N4O4SColore e forma:SolidPeso molecolare:526.69Prostaglandin E1 ethanolamide
CAS:<p>Prostaglandin E1 ethanolamide, an analog of Prostaglandin E1 (PGE1), can potentially inhibit the GLI2-induced expression of target genes such as Gli1 and Ptch1, thereby reducing tumor growth [1].</p>Formula:C22H39NO5Colore e forma:SolidPeso molecolare:397.55Cyanopindolol fumarate
CAS:<p>Cyanopindolol fumarate is a 5-HT receptor antagonist [1].</p>Formula:C16H21N3O2C4H4O4Colore e forma:SolidPeso molecolare:345.4Vemtoberant
CAS:<p>Vemtoberant is a β3 adrenergic antagonist used in β3-related disorder research like heart failure.</p>Formula:C29H37N3O8S2Colore e forma:SolidPeso molecolare:619.75E1R
CAS:<p>E1R is a positive sigma-1 receptor (Sig1R PAM) allosteric modulator. It has a cognition-enhancing activity.</p>Formula:C13H16N2O2Colore e forma:SolidPeso molecolare:232.28LY320954
CAS:<p>LY320954 is an antagonist of 5-HT2A receptor.</p>Formula:C21H26N4O3Purezza:98%Colore e forma:SolidPeso molecolare:382.46GP3269
CAS:<p>GP3269 is a selective, potent, orally active human adenosine kinase (AK) inhibitor (IC50: 11 nM) with anticonvulsant effects in rats.</p>Formula:C23H21FN4O3Colore e forma:SolidPeso molecolare:420.4411-deoxy-16,16-dimethyl Prostaglandin E2
CAS:<p>11-Deoxy-16,16-dimethyl Prostaglandin E2 (11-deoxy-16,16-dimethyl PGE2) is a stable synthetic analog of Prostaglandin E2 (PGE2), acting as an agonist for both EP2 and EP3 receptors. It effectively inhibits gastric acid secretion and ulcer formation in rats, with ED50 values of 1 mg/kg and 0.021 mg/kg, respectively. This compound is also 900 times more potent than Prostaglandin F2α (PGF2α) in inducing contraction of human respiratory tract smooth muscle in vitro.</p>Formula:C22H36O4Colore e forma:SolidPeso molecolare:364.526MSX-2
CAS:<p>MSX-2 is an A2A adenosine receptor antagonist.</p>Formula:C21H22N4O4Purezza:98%Colore e forma:SolidPeso molecolare:394.42GR 127935 hydrochloride
CAS:<p>5-HT1B/1D receptor antagonist</p>Formula:C29H32ClN5O3Purezza:98%Colore e forma:SolidPeso molecolare:534.05PD 165929
CAS:<p>PD 165929 is a selective antagonist of Bombesin BB1.</p>Formula:C37H47N5O2Purezza:98%Colore e forma:SolidPeso molecolare:593.8CRTH2-IN-1
CAS:<p>CRTH2-IN-1 is a selective prostaglandin D2 receptor DP2 (CRTH2) antagonist, a Ramatroban analog, with an IC50 of 6 nM in the human DP2 binding assay.</p>Formula:C21H21FN2O4SPurezza:98%Colore e forma:SolidPeso molecolare:416.47Velagliflozin proline hydrate
CAS:<p>Velagliflozin proline hydrate, an oral SGLT2 inhibitor, reduces blood sugar by inhibiting renal glucose reabsorption.</p>Formula:C28H36N2O8Colore e forma:SolidPeso molecolare:528.59TASP0376377
CAS:<p>TASP0376377 is a potent antagonist of CRTH2.</p>Formula:C25H16Cl2N2O4Colore e forma:SolidPeso molecolare:479.31YM44778
CAS:<p>YM44778 is a NK1-receptor antagonist for treating restless legs syndrome.</p>Formula:C34H39Cl2N3O5Colore e forma:SolidPeso molecolare:640.6MRS 1754
CAS:<p>MRS 1754 is a selective antagonist radioligand for the A2B adenosine receptor. It has a very low affinity for A1 and A3 receptors of both humans and rats.</p>Formula:C26H26N6O4Purezza:97.57% - 99.3%Colore e forma:SolidPeso molecolare:486.52Ubrogepant
CAS:<p>Ubrogepant (MK-1602) is an antagonist of calcitonin gene-related peptide receptor that can be used in the acute treatment of migraine studies.</p>Formula:C29H26F3N5O3Purezza:99.452% - 99.78%Colore e forma:SolidPeso molecolare:549.54KUC-7322
CAS:<p>Ritobegron is used as a selective β3-adrenoceptor agonist and the prodrug of the active compound, KUC-7322.</p>Formula:C21H27NO5Colore e forma:SolidPeso molecolare:373.44Sonepiprazole
CAS:<p>Sonepiprazole (PNU-101387G) is a chemical compound known for its selective antagonistic properties toward D4 dopamine receptors, exhibiting dissociation</p>Formula:C21H27N3O3SPurezza:99.81%Colore e forma:SolidPeso molecolare:401.52Hh-Ag1.5
CAS:<p>Hh-Ag1.5 is a dual Hedgehog/Smo agonist (EC50/Ki: 0.5-2.3 nM), reprograms hepatic stem cells, and differentiates hiPSCs into neural/skin cells.</p>Formula:C28H26ClF2N3OSPurezza:99.8%Colore e forma:SolidPeso molecolare:526.04LX-1031
CAS:<p>LX-1031 is an effective inhibitor of tryptophan 5-hydroxylase. LX-1031 decreases serotonin (5-HT) synthesis peripherally.</p>Formula:C28H25F3N4O4Purezza:97.123% - 98.97%Colore e forma:SolidPeso molecolare:538.52GR-127935
CAS:<p>GR-127935 is a potent and selective 5-HT1B/1D receptor antagonist.</p>Formula:C29H31N5O3Colore e forma:SolidPeso molecolare:497.59ATL802
CAS:<p>ATL802 is an adenosine A2B Receptor antagonist.</p>Formula:C24H22F3N7O3Purezza:98%Colore e forma:SolidPeso molecolare:513.47TASP 0277308
CAS:<p>NH2-UAMC1110 TFA is an aminobutoxy derivative of UAMC1110 used in the synthesis of FAPI-QS. UAMC1110 is a fibroblast activating protein (fap) inhibitor.</p>Formula:C23H28Cl2N6O3SColore e forma:SolidPeso molecolare:539.48Firazorexton hydrate
CAS:<p>Firazorexton hydrate (TAK-994) is a brain-penetrant and orally active agonist of the orexin type 2 receptor (OX2R) with a potent EC50 of 19 nM.</p>Formula:C22H25F3N2O4SH2OColore e forma:SolidPeso molecolare:497.53NAD 299 hydrochloride
CAS:<p>Selective, high affinity 5-HT1A receptor antagonist</p>Formula:C18H24ClFN2O2Purezza:98%Colore e forma:SolidPeso molecolare:354.85NAS-181
CAS:<p>NAS-181 is a potent and selective rat 5-hydroxytryptamine 1B (r5-HT1B) antagonist (Ki: 47 nM).NAS-181 enhances the accumulation of 5-HTP in rat brain regions.</p>Formula:C20H30N2O7SColore e forma:SolidPeso molecolare:442.53RP-23618
CAS:<p>RP-23618 is a non-peptidic antagonist of RANTES.</p>Formula:C30H35N5O3S2Purezza:98%Colore e forma:SolidPeso molecolare:577.76IWP-051
CAS:<p>IWP-051: potent oral sGC stimulator, >99% protein bound, stable, permeable, no Caco-2 efflux, potential for daily dose.</p>Formula:C17H11F2N5O2Colore e forma:SolidPeso molecolare:355.3MK3577
CAS:<p>MK3577 is a glucagon receptor antagonist.</p>Formula:C30H30ClFN2O3Colore e forma:SolidPeso molecolare:521.02Dersalazine sodium
CAS:<p>Dersalazine, potential ulcerative colitis drug, inhibits PAF & TNFα, reduces inflammation and MPO activity in rats.</p>Formula:C35H32N6NaO4Purezza:98%Colore e forma:SolidPeso molecolare:623.669NH2-c[X-R-L-S-X]-K-G-P-(D-2Nal)
CAS:<p>Compound 40, a cyclic Ape13 analogue and potent APJ agonist (Ki 5.7 nM), shows Gα12-bias and longer half-life.</p>Formula:C49H73N13O11Colore e forma:SolidPeso molecolare:1020.18SUCNR1-IN-1
CAS:<p>SUCNR1-IN-1 (Compound 20) serves as a potent SUCNR1 inhibitor, exhibiting an IC50 of 88 nM against hSUCNR1.</p>Formula:C26H22ClF3N2O4Colore e forma:SolidPeso molecolare:518.91UCB-35440
CAS:<p>UCB-35440, a 5-lipoxygenase inhibitor and a histamine H1 receptor antagonist, is used potentially for the treatment of dermatitis.</p>Formula:C31H34ClN5O4Colore e forma:SolidPeso molecolare:576.09CP-96486
CAS:<p>CP-96486 is a potent and orally active antagonist of leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor (Kis: 20 and 24 nM).</p>Formula:C31H23ClN4OPurezza:98%Colore e forma:SolidPeso molecolare:502.9916-phenoxy tetranor Prostaglandin E2
CAS:<p>16-phenoxy tetranor PGE2, the free acid form of sulprostone, results from the hydrolysis of the methylsulfonamide bond. It is identified as a minor metabolite in human plasma following the parenteral administration of sulprostone.</p>Formula:C22H28O6Colore e forma:SolidPeso molecolare:388.462-Methyl-5-HT
CAS:<p>2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.</p>Formula:C11H14N2OPurezza:97.18%Colore e forma:SolidPeso molecolare:190.24Saredutant
CAS:<p>Saredutant (SR 48968) is a selective neurokinin-2 (NK2) receptor antagonist that inhibits neurokinin A by blocking NK2 receptor, antidepressant and anxiolytic.</p>Formula:C31H35Cl2N3O2Purezza:99.12%Colore e forma:SolidPeso molecolare:552.54Tafluprost ethyl ester
CAS:<p>Tafluprost, an analog of prostaglandin F2α (PGF2α) that primarily targets the FP receptor, is employed in glaucoma treatment. Tafluprost (free acid) serves as a potent FP receptor agonist with a Ki value of 0.4 nM. Its derivative, tafluprost ethyl ester, potentially offers enhanced lipid solubility relative to its free acid form, possibly leading to superior tissue absorption and reduced effective concentration requirements.</p>Formula:C24H32F2O5Colore e forma:SolidPeso molecolare:438.512VCH-286
CAS:<p>VCH-286 is a C-C chemokine receptor type 5 (CCR5) receptor antagonist.</p>Formula:C34H50F2N4O3Purezza:98%Colore e forma:SolidPeso molecolare:600.78UWA-101 hydrochloride
CAS:<p>UWA-101 hydrochloride is a selective, non-cytotoxic inhibitor of DAT/SERT, demonstrating EC50 values of 3.6 µM for DAT and 2.3 µM for SERT inhibition. It mitigates motor disorders and other side effects associated with dopaminergic agent use (e.g., L-DOPA) without exhibiting psychotropic effects. This compound is utilized in research focused on neurodegenerative conditions like Parkinson's disease [1] [2].</p>Formula:C13H18ClNO2Colore e forma:SolidPeso molecolare:255.74MLN-3897
CAS:<p>MLN-3897 is an oral CCR1 antagonist, Ki 2.3 nM, blocks 125I-MIP-1α binding, and inhibits Akt signaling in MM cells.</p>Formula:C30H31ClN2O4Purezza:98.62%Colore e forma:SolidPeso molecolare:519.03LY3154885
CAS:<p>LY3154885 is an orally active dopamine D1 receptor orthosteric modulator (PAM) that reduces the risk of drug-drug interactions (DDI).</p>Formula:C23H23Cl2N3O2Colore e forma:SolidPeso molecolare:444.35Frovatriptan
CAS:<p>Frovatriptan, potent 5-HT 1B/D agonist, shows high cerebroselectivity and efficacy for migraine with aura.</p>Formula:C14H17N3OColore e forma:SolidPeso molecolare:243.3L 743310
CAS:<p>L 743310 is an antagonist of the neurokinin-1 receptor.</p>Formula:C30H33BrF6N4O2Purezza:98%Colore e forma:SolidPeso molecolare:675.5Obestatin(rat) TFA
CAS:<p>Obestatin(rat) TFA, a 23-amino-acid peptide, modulates appetite, gut motility, and body weight; binds GPR39; has anti-inflammatory and antioxidant effects.</p>Formula:C116H175F3N34O33Colore e forma:SolidPeso molecolare:2630.83LY-426965
CAS:<p>LY-426965 is a selective, potent, orally bioavailable 5-HT1A antagonist.</p>Formula:C28H38N2O2Colore e forma:SolidPeso molecolare:434.61CCG-63802
CAS:<p>CCG-63802 is a reversible small-molecule inhibitor of regulator of G protein signaling (RGS) proteins.</p>Formula:C26H18N4O2SPurezza:90%Colore e forma:SolidPeso molecolare:450.51NBI 35965 methanesulfonate
CAS:NBI 35965 hydrochloride is a CRF1 antagonist.Formula:C22H26Cl2N4O3SPurezza:98%Colore e forma:SolidPeso molecolare:497.44Crisdesalazine
CAS:<p>Crisdesalazine (AAD 2004) is an inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1).</p>Formula:C16H14F3NO3Purezza:98.96%Colore e forma:SolidPeso molecolare:325.282-Furoyl-LIGRLO-amide TFA
CAS:<p>2-Furoyl-LIGRLO-amide TFA is a potent and selective agonist of the proteinase-activated receptor 2 (PAR2), exhibiting a pD2 value of 7.0 [1] [2].</p>Formula:C38H64F3N11O10Colore e forma:SolidPeso molecolare:891.98A-349821
CAS:<p>A-349821 is an H3 receptor agonist radioligand.</p>Formula:C28H35F3N2O5Colore e forma:SolidPeso molecolare:536.59BMS-194449
CAS:<p>BMS-194449 is a full beta 3 agonist.</p>Formula:C24H24F4N2O6SColore e forma:SolidPeso molecolare:544.52CP-96021 hydrochloride
CAS:CP-96021 hydrochloride is a potent and orally active antagonist of leukotriene D4 (LTD4)/platelet activating factor receptor (Kis: 34 nM and 37 nM).Formula:C29H22ClFN4OSPurezza:98%Colore e forma:SolidPeso molecolare:529.03EP2 receptor agonist 4
CAS:<p>EP2 receptor agonist 4 selectively activates the EP2 receptor with an efficacy concentration (EC50) of 43 nM [1].</p>Formula:C23H36O5Colore e forma:SolidPeso molecolare:392.53
